PT94188A - Processo para a purificacao de acidos aminometilenofosfonicos - Google Patents

Processo para a purificacao de acidos aminometilenofosfonicos

Info

Publication number: PT94188A
Authority: PT; Portugal
Prior art keywords: aminomethylenophosphonic; purification; acids; aminomethylenophosphonic acids
Prior art date: 1989-08-04

Application number

PT94188A

Other languages

English (en)

Other versions

PT94188B (pt

Inventor

Jaime Simon

Joseph R Garlich

Tipton T Masterson

Original Assignee

Dow Chemical Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1989-08-04

Filing date

1990-05-29

Publication date

1991-04-18

1990-05-29 Application filed by Dow Chemical Co filed Critical Dow Chemical Co

1991-04-18 Publication of PT94188A publication Critical patent/PT94188A/pt

1996-12-31 Publication of PT94188B publication Critical patent/PT94188B/pt

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/44—Amides thereof
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6524—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/025—Purification; Separation; Stabilisation; Desodorisation of organo-phosphorus compounds
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3808—Acyclic saturated acids which can have further substituents on alkyl
- C07F9/3817—Acids containing the structure (RX)2P(=X)-alk-N...P (X = O, S, Se)

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Crystallography & Structural Chemistry (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Crystals, And After-Treatments Of Crystals (AREA)

PT94188A 1989-08-04 1990-05-29 Processo para a purificacao de acidos aminometilenofosfonicos PT94188B (pt)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
US07/389,441 US4937333A (en)	1989-08-04	1989-08-04	Method for purifying aminomethylenephosphonic acids for pharmaceutical use

Publications (2)

Publication Number	Publication Date
PT94188A true PT94188A (pt)	1991-04-18
PT94188B PT94188B (pt)	1996-12-31

Family

ID=23538280

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT94188A PT94188B (pt)	1989-08-04	1990-05-29	Processo para a purificacao de acidos aminometilenofosfonicos

Country Status (38)

Country	Link
US (1)	US4937333A (pt)
EP (1)	EP0411941B1 (pt)
JP (1)	JP2922263B2 (pt)
KR (2)	KR0178779B1 (pt)
CN (2)	CN1024196C (pt)
AP (1)	AP163A (pt)
AT (1)	ATE140459T1 (pt)
AU (1)	AU634267B2 (pt)
BG (1)	BG60519B1 (pt)
BR (2)	BR9003694A (pt)
CA (1)	CA2020950C (pt)
CZ (1)	CZ290556B6 (pt)
DD (1)	DD297414A5 (pt)
DE (1)	DE69027818T2 (pt)
DK (1)	DK0411941T3 (pt)
DZ (1)	DZ1436A1 (pt)
EG (1)	EG19250A (pt)
ES (1)	ES2090105T3 (pt)
FI (1)	FI105033B (pt)
GR (1)	GR3020932T3 (pt)
HK (1)	HK1007558A1 (pt)
HU (1)	HU205128B (pt)
IE (1)	IE902812A1 (pt)
IL (3)	IL95094A (pt)
LV (1)	LV10718B (pt)
MA (1)	MA21922A1 (pt)
NO (2)	NO178196C (pt)
NZ (2)	NZ247888A (pt)
OA (1)	OA09300A (pt)
PH (1)	PH26901A (pt)
PL (2)	PL164908B1 (pt)
PT (1)	PT94188B (pt)
RO (1)	RO105967B1 (pt)
RU (1)	RU1838321C (pt)
SA (1)	SA90110175B1 (pt)
SK (1)	SK279107B6 (pt)
YU (1)	YU47368B (pt)
ZA (1)	ZA905564B (pt)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4937333A (en) *	1989-08-04	1990-06-26	The Dow Chemical Company	Method for purifying aminomethylenephosphonic acids for pharmaceutical use
MC2260A1 (fr) *	1990-06-18	1993-04-26	Dow Chemical Co	Formulations de produits radiopharmaceutiques,leur methode d'administration et leur procede de preparation
EP0494603A3 (en) *	1991-01-10	1993-10-20	Hoechst Ag	Process for extractive separation of phospho- and sulphobetaines from acidic reaction solutions
US5410043A (en) *	1991-12-06	1995-04-25	Schering Aktiengesellschaft	Process for the production of mono-N-substituted tetraaza macrocycles
US5320829A (en) *	1991-12-10	1994-06-14	The Dow Chemical Company	Oral compositions for inhibiting plaque formation
DE4218744C2 (de) *	1992-06-04	1997-11-06	Schering Ag	Verfahren zur Herstellung von N-ß-Hxdroxyalkyl-tri-N-carboxylalkyl-1,4,7,10-tetraazacyclododecan- und N-ß-Hydroxyalkyl-tri-N-carboxyalkyl-1,4,8,11-tetraazacyclotetradecan-Derivaten und deren Metallkomplexe
US5495042A (en) *	1993-11-04	1996-02-27	Cytogen Corporation	Non-alkaline purification of aminophosphonic acids
JP2003501488A (ja)	1999-06-11	2003-01-14	ネオルックスコーポレイション	骨髄抑制のための高投与量放射性核種錯体
US7094885B2 (en) *	1999-07-11	2006-08-22	Neorx Corporation	Skeletal-targeted radiation to treat bone-associated pathologies
AU1092601A (en) *	1999-10-18	2001-04-30	Dow Global Technologies Inc.	Aminoalkylenephosphonates for treatment of bone disorders
US6794371B1 (en) *	1999-10-18	2004-09-21	The Dow Chemical Company	Aminoalkylenephosphonates for treatment of bone disorders
AU2002249935A1 (en) *	2001-01-08	2002-08-19	Neorx Corporation	Radioactively labelled conjugates of phosphonates
CN100368047C (zh) *	2002-12-27	2008-02-13	住友化学株式会社	结晶方法和结晶装置
WO2006020779A2 (en) *	2004-08-10	2006-02-23	Dow Global Technologies Inc.	Targeting chelants and chelates
CN101381377B (zh) *	2008-10-23	2011-05-04	山东省泰和水处理有限公司	一种适用于电子级固体己二胺四亚甲基膦酸的制备工艺
JP5581832B2 (ja) *	2010-06-11	2014-09-03	三菱瓦斯化学株式会社	高純度アミノメチレンホスホン酸の製造方法
CN103724373A (zh) *	2014-01-02	2014-04-16	山东省泰和水处理有限公司	多聚甲醛生产氨基三亚甲基膦酸的方法
DE102014210378B4 (de)	2014-06-02	2018-10-04	Zschimmer & Schwarz Mohsdorf GmbH &Co.KG.	Verfahren zur Herstellung hochreiner Aminoalkylenphosphonsäuren
WO2015185548A1 (de) *	2014-06-02	2015-12-10	Zschimmer & Schwarz Gmbh & Co.Kg	Verfahren zur herstellung kristalliner dtpmp
CN113263580A (zh) *	2021-04-23	2021-08-17	广东工业大学	一种多功能床头柜制造设备

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US2599807A (en) *	1950-06-01	1952-06-10	Frederick C Bersworth	Alkylene polyamine methylene phosphonic acids
NL285361A (pt) *	1961-11-13	1900-01-01
US3738937A (en) *	1970-05-08	1973-06-12	Textilana Corp	Polyalkylene polyamino polykis methylene phosphonic acids and salts thereof and methods for producing same
NL7903500A (nl) *	1979-05-04	1980-11-06	Philips Nv	Verbrandingsflitslamp en flitsinrichting voorzien van verscheidene verbrandingsflitslampen.
JPS5775990A (en) *	1980-10-27	1982-05-12	Mitsubishi Gas Chem Co Inc	Preparation of n,n,n',n'-tetra(phosphonomethyl) diaminoalkane
EP0225409A1 (en) *	1985-12-02	1987-06-16	The Dow Chemical Company	Organic amine phosphonic acid complexes for the treatment of calcific tumors
US4937333A (en) *	1989-08-04	1990-06-26	The Dow Chemical Company	Method for purifying aminomethylenephosphonic acids for pharmaceutical use
GB8903023D0 (en) *	1989-02-10	1989-03-30	Parker David	Chemical compounds
DE3911816A1 (de) *	1989-04-11	1990-10-25	Hoechst Ag	Substituierte 1,4,7,10-tetraazacyclotridecane, verfahren zu deren herstellung sowie verwendung derselben zur markierung von substanzen mit radionukliden

1989
- 1989-08-04 US US07/389,441 patent/US4937333A/en not_active Expired - Lifetime
1990
- 1990-05-29 PT PT94188A patent/PT94188B/pt not_active IP Right Cessation
- 1990-07-11 NZ NZ24788890A patent/NZ247888A/en unknown
- 1990-07-11 CA CA002020950A patent/CA2020950C/en not_active Expired - Lifetime
- 1990-07-11 NZ NZ234464A patent/NZ234464A/en unknown
- 1990-07-16 IL IL9509490A patent/IL95094A/en active IP Right Grant
- 1990-07-16 IL IL11086190A patent/IL110861A/xx active IP Right Grant
- 1990-07-16 ZA ZA905564A patent/ZA905564B/xx unknown
- 1990-07-24 BR BR909003694A patent/BR9003694A/pt not_active Application Discontinuation
- 1990-07-24 JP JP2194121A patent/JP2922263B2/ja not_active Expired - Lifetime
- 1990-07-25 YU YU145390A patent/YU47368B/sh unknown
- 1990-07-26 PH PH40907A patent/PH26901A/en unknown
- 1990-07-28 CN CN90104982A patent/CN1024196C/zh not_active Expired - Lifetime
- 1990-07-28 CN CN93108500A patent/CN1031191C/zh not_active Expired - Fee Related
- 1990-07-31 SK SK3796-90A patent/SK279107B6/sk unknown
- 1990-07-31 DZ DZ900139A patent/DZ1436A1/fr active
- 1990-07-31 CZ CZ19903796A patent/CZ290556B6/cs not_active IP Right Cessation
- 1990-08-02 DE DE69027818T patent/DE69027818T2/de not_active Expired - Lifetime
- 1990-08-02 DK DK90308524.9T patent/DK0411941T3/da active
- 1990-08-02 ES ES90308524T patent/ES2090105T3/es not_active Expired - Lifetime
- 1990-08-02 AT AT90308524T patent/ATE140459T1/de not_active IP Right Cessation
- 1990-08-02 RO RO145690A patent/RO105967B1/ro unknown
- 1990-08-02 MA MA22192A patent/MA21922A1/fr unknown
- 1990-08-02 EP EP90308524A patent/EP0411941B1/en not_active Expired - Lifetime
- 1990-08-03 DD DD90343237A patent/DD297414A5/de unknown
- 1990-08-03 PL PL90300181A patent/PL164908B1/pl unknown
- 1990-08-03 IE IE281290A patent/IE902812A1/en not_active IP Right Cessation
- 1990-08-03 OA OA59828A patent/OA09300A/xx unknown
- 1990-08-03 PL PL90286349A patent/PL166453B1/pl unknown
- 1990-08-03 AP APAP/P/1990/000202A patent/AP163A/en active
- 1990-08-03 BG BG92627A patent/BG60519B1/bg unknown
- 1990-08-03 FI FI903864A patent/FI105033B/fi active IP Right Grant
- 1990-08-03 KR KR1019900011923A patent/KR0178779B1/ko not_active IP Right Cessation
- 1990-08-03 HU HU904890A patent/HU205128B/hu unknown
- 1990-08-03 NO NO903419A patent/NO178196C/no not_active IP Right Cessation
- 1990-08-03 RU SU904830923A patent/RU1838321C/ru active
- 1990-08-04 EG EG46290A patent/EG19250A/xx active
- 1990-08-06 AU AU60237/90A patent/AU634267B2/en not_active Expired
- 1990-12-18 SA SA90110175A patent/SA90110175B1/ar unknown
1993
- 1993-06-30 LV LVP-93-934A patent/LV10718B/lv unknown
1994
- 1994-09-05 IL IL11086194A patent/IL110861A0/xx unknown
1996
- 1996-09-03 GR GR960402289T patent/GR3020932T3/el unknown
1997
- 1997-02-12 NO NO970653A patent/NO970653D0/no unknown
- 1997-05-14 BR BR1101174-2A patent/BR1101174A/pt active IP Right Grant
1998
- 1998-06-25 HK HK98106634A patent/HK1007558A1/xx not_active IP Right Cessation
- 1998-06-29 KR KR1019980024928A patent/KR0178877B1/ko not_active IP Right Cessation

Also Published As

Publication number	Publication date
PL286349A1 (en)	1991-05-20
CN1049351A (zh)	1991-02-20
YU145390A (sh)	1992-09-07
HUT54698A (en)	1991-03-28
ZA905564B (en)	1992-03-25
PL166453B1 (pl)	1995-05-31
CN1091744A (zh)	1994-09-07
EG19250A (en)	1994-09-29
BR9003694A (pt)	1991-09-03
EP0411941A3 (en)	1992-04-15
HU205128B (en)	1992-03-30
DE69027818T2 (de)	1996-11-21
AP163A (en)	1992-01-11
PL164908B1 (pl)	1994-10-31
SK379690A3 (en)	1998-06-03
ES2090105T3 (es)	1996-10-16
NO903419D0 (no)	1990-08-03
AP9000202A0 (en)	1990-10-31
CA2020950A1 (en)	1991-02-05
PT94188B (pt)	1996-12-31
KR0178877B1 (ko)	1999-05-15
GR3020932T3 (en)	1996-12-31
DE69027818D1 (de)	1996-08-22
BG60519B1 (bg)	1995-07-28
ATE140459T1 (de)	1996-08-15
BR1101174A (pt)	2000-08-08
AU634267B2 (en)	1993-02-18
EP0411941B1 (en)	1996-07-17
LV10718B (en)	1996-04-20
US4937333A (en)	1990-06-26
IL110861A0 (en)	1994-11-28
DK0411941T3 (da)	1996-11-11
SK279107B6 (sk)	1998-06-03
CA2020950C (en)	2000-04-11
OA09300A (en)	1992-09-15
CN1024196C (zh)	1994-04-13
RU1838321C (ru)	1993-08-30
HK1007558A1 (en)	2003-07-10
NO178196B (no)	1995-10-30
BG92627A (bg)	1993-12-24
PH26901A (en)	1992-12-03
IL95094A (en)	1995-05-26
IE902812A1 (en)	1991-02-27
NO178196C (no)	1996-02-07
HU904890D0 (en)	1991-01-28
YU47368B (sh)	1995-01-31
RO105967B1 (ro)	1993-01-30
FI105033B (fi)	2000-05-31
SA90110175B1 (ar)	2004-03-09
NO903419L (no)	1991-02-05
KR0178779B1 (ko)	1999-05-15
KR910004642A (ko)	1991-03-29
DD297414A5 (de)	1992-01-09
CN1031191C (zh)	1996-03-06
MA21922A1 (fr)	1991-04-01
DZ1436A1 (fr)	2004-09-13
EP0411941A2 (en)	1991-02-06
JPH0366697A (ja)	1991-03-22
CZ290556B6 (cs)	2002-08-14
NZ234464A (en)	1994-06-27
LV10718A (lv)	1995-06-20
CZ379690A3 (cs)	2000-08-16
IL110861A (en)	1999-07-14
AU6023790A (en)	1991-02-07
JP2922263B2 (ja)	1999-07-19
FI903864A0 (fi)	1990-08-03
NO970653L (no)	1991-02-05
NO970653D0 (no)	1997-02-12
NZ247888A (en)	1994-07-26
IL95094A0 (en)	1991-06-10

Publication	Publication Date	Title
PT88044A (pt)	1989-06-30	Processo para a preparacao de acidos tetra-hidrocarbazole-1-alcanoicos
BR8802484A (pt)	1988-12-20	Processo para a preparacao de isocianatos
PT90293A (pt)	1989-11-10	Processo para a preparacao de macrolidos
PT92919A (pt)	1990-07-31	Processo para a preparacao de agentes ansioliticos bis-azabiciclicos
PT94188A (pt)	1991-04-18	Processo para a purificacao de acidos aminometilenofosfonicos
PT91895A (pt)	1990-04-30	Processo para a preparacao de 9h-purinas substituidas
PT92786A (pt)	1990-07-31	Processo para a preparacao de compostos de tiazol
BR8804284A (pt)	1989-03-21	Processo para a preparacao de acidos etercarboxilicos
PT89075A (pt)	1988-12-01	Processo para a preparacao de diacidos diarilestiril-quinolinicos
BR8906327A (pt)	1990-08-21	Processo para a preparacao de organoclorossilanos
PT92638A (pt)	1990-06-29	Processo para a preparacao de poliazamacrociclos mono-n-alquilados
PT90854A (pt)	1989-12-29	Processo para a preparacao de 1-aril-2-naftoilaminas
BR9001503A (pt)	1991-04-16	Processo para a preparacao de alquil-halogenossilanos
PT89039A (pt)	1988-12-01	Processo para a preparacao de l-ramnose
BR8803678A (pt)	1989-02-14	Processo para a preparacao de polieteramidas
PT89056A (pt)	1989-11-30	Processo para a preparacao de hidroxilaminas substituidas
BR8704110A (pt)	1988-04-12	Processo para a producao de anidrido ftalico
BR8903367A (pt)	1990-02-13	Processo para a preparacao de organoclorossilanos
BR8806351A (pt)	1989-08-22	Processo para a preparacao de fenil-ureias
PT90353A (pt)	1989-11-10	Processo para a producao de polipeptideos
BR9002408A (pt)	1991-08-06	Processo para a producao de poliarilatos
BR8902030A (pt)	1989-12-05	Processo para a preparacao de n-fosfonometilglicina
PT94890A (pt)	1991-04-18	Processo para a preparacao de compostos azofenilicos
BR9303969A (pt)	1994-08-02	Processo para produção de ácidos 2-arilbenzimidazol-5-sulfônicos
PT92507A (pt)	1990-06-29	Processo para a preparacao de alfa-ciano-beta-oxopropionamidas

Legal Events

Date	Code	Title	Description
1996-12-31	FG3A	Patent granted, date of granting	Effective date: 19960924
2010-04-05	MM4A	Annulment/lapse due to non-payment of fees, searched and examined patent	Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 20100324

Date

Code

Title

Description

1996-12-31

FG3A

Patent granted, date of granting

Effective date: 19960924

2010-04-05

MM4A

Annulment/lapse due to non-payment of fees, searched and examined patent

Free format text: LAPSE DUE TO NON-PAYMENT OF FEES

Effective date: 20100324