PT89075A - Processo para a preparacao de diacidos diarilestiril-quinolinicos - Google Patents
Processo para a preparacao de diacidos diarilestiril-quinolinicosInfo
- Publication number
- PT89075A PT89075A PT89075A PT8907588A PT89075A PT 89075 A PT89075 A PT 89075A PT 89075 A PT89075 A PT 89075A PT 8907588 A PT8907588 A PT 8907588A PT 89075 A PT89075 A PT 89075A
- Authority
- PT
- Portugal
- Prior art keywords
- kinolinic
- diarilestiryl
- diacids
- preparation
- kinolinic diacids
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/36—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pulmonology (AREA)
- Immunology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US12505087A | 1987-11-25 | 1987-11-25 |
Publications (2)
Publication Number | Publication Date |
---|---|
PT89075A true PT89075A (pt) | 1988-12-01 |
PT89075B PT89075B (pt) | 1993-04-30 |
Family
ID=22417988
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT89075A PT89075B (pt) | 1987-11-25 | 1988-11-24 | Processo para a preparacao de diacidos diarilestiril-quinolinicos |
Country Status (10)
Country | Link |
---|---|
EP (1) | EP0318093A3 (pt) |
JP (1) | JPH0686433B2 (pt) |
KR (1) | KR890008104A (pt) |
AU (1) | AU2589688A (pt) |
CA (1) | CA1339802C (pt) |
DK (1) | DK655288A (pt) |
IL (1) | IL88433A0 (pt) |
NZ (1) | NZ227036A (pt) |
PT (1) | PT89075B (pt) |
ZA (1) | ZA888766B (pt) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5204358A (en) * | 1987-11-25 | 1993-04-20 | Merck Frosst Canada, Inc. | Hetaryl styryl quinolines as leukotriene inhibitors |
US4968702A (en) * | 1989-01-17 | 1990-11-06 | American Cyanamid Company | Substituted quinolinecarboxylic acids |
NZ233752A (en) * | 1989-05-24 | 1993-05-26 | Merck Frosst Canada Inc | Substituted quinoline derivatives, preparation and pharmaceutical compositions thereof |
DE3927930A1 (de) * | 1989-08-24 | 1991-02-28 | Bayer Ag | Cyclisch substituierte (chinolin-2-yl-methoxy)phenyl-essig-saeure-derivate |
US5021576A (en) * | 1989-10-27 | 1991-06-04 | American Home Products Corporation | 2-Anilino phenylacetic acid derivatives |
US5856322A (en) * | 1990-10-12 | 1999-01-05 | Merck Frosst Canada, Inc. | Unsaturated hydroxyalkylquinoline acids as leukotriene antagonists |
CA2053209C (en) * | 1990-10-12 | 1998-12-08 | Michel L. Belley | Unsaturated hydroxyalkylquinoline acids as leukotriene antagonists |
EP0480716A1 (en) * | 1990-10-12 | 1992-04-15 | Merck Frosst Canada Inc. | Saturated hydroxyalkylquinoline acids as leukotriene antagonists |
DE69113735T2 (de) * | 1990-10-12 | 1996-06-13 | Merck Frosst Canada Inc | Hydroxyalkylchinolin Äther Säure als Leukotrien-Antagoniste. |
IE920499A1 (en) * | 1991-02-21 | 1992-08-26 | Merck Frosst Canada Inc | Quinoline-containing ketoacids as leukotriene antagonists |
US5149703A (en) * | 1991-09-06 | 1992-09-22 | Merck Frosst Canada, Inc. | Quinoline-substituted chromans and related compounds as leukotriene antagonists |
US5270324A (en) * | 1992-04-10 | 1993-12-14 | Merck Frosst Canada, Inc. | Fluorinated hydroxyalkylquinoline acids as leukotriene antagonists |
US5506227A (en) * | 1992-04-13 | 1996-04-09 | Merck Frosst Canada, Inc. | Pyridine-substituted benzyl alcohols as leukotriene antagonists |
EP0780127A1 (en) | 1995-12-19 | 1997-06-25 | The Procter & Gamble Company | A nasal spray containing a steroid and a antihistamine |
AU3868497A (en) * | 1996-08-26 | 1998-03-19 | Yamanouchi Pharmaceutical Co., Ltd. | Benzenesulfone compounds and salts thereof |
WO1998032734A1 (en) * | 1997-01-22 | 1998-07-30 | Rhone-Poulenc Rorer Pharmaceuticals Inc. | SUBSTITUTED β-THIOCARBOXYLIC ACIDS |
FR2761687B1 (fr) * | 1997-04-08 | 2000-09-15 | Centre Nat Rech Scient | Derives de quinoleines, possedant notamment des proprietes antivirales, leurs preparations et leurs applications biologiques |
JP4725634B2 (ja) * | 2008-11-13 | 2011-07-13 | トヨタ自動車株式会社 | 無段変速機 |
ES2781480T3 (es) | 2011-07-26 | 2020-09-02 | Sun Pharma Advanced Res Co Ltd | Antagonistas del cisteinil leucotrieno |
AU2014225550C1 (en) | 2013-03-08 | 2017-08-17 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Potent and selective inhibitors of monoamine transporters; method of making; and use thereof |
US11365195B2 (en) | 2017-11-13 | 2022-06-21 | The United States Of America, As Represented By The Secretary, Department Of Health And Human Services | Atypical inhibitors of monoamine transporters; method of making; and use thereof |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK282986A (da) * | 1985-06-18 | 1987-02-24 | Merck Frosst Canada Inc | Substitueret quinolin og farmaceutisk praeparat indeholdende en saadan forbindelse |
IE59889B1 (en) * | 1986-02-14 | 1994-04-20 | Merck Frosst Canada Inc | 2-substituted quinoline dioic acids |
ATE83376T1 (de) * | 1986-03-13 | 1993-01-15 | Rhone Poulenc Rorer Int | Chinolinylaether tetrazole als mittel zur behandlung von hyperempfindlichen krankheiten. |
-
1988
- 1988-11-21 EP EP19880202606 patent/EP0318093A3/en not_active Ceased
- 1988-11-21 IL IL88433A patent/IL88433A0/xx unknown
- 1988-11-22 CA CA000583726A patent/CA1339802C/en not_active Expired - Fee Related
- 1988-11-22 NZ NZ227036A patent/NZ227036A/xx unknown
- 1988-11-23 ZA ZA888766A patent/ZA888766B/xx unknown
- 1988-11-24 AU AU25896/88A patent/AU2589688A/en not_active Abandoned
- 1988-11-24 DK DK655288A patent/DK655288A/da unknown
- 1988-11-24 PT PT89075A patent/PT89075B/pt not_active IP Right Cessation
- 1988-11-24 KR KR1019880015470A patent/KR890008104A/ko not_active Application Discontinuation
- 1988-11-25 JP JP63296383A patent/JPH0686433B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
KR890008104A (ko) | 1989-07-08 |
DK655288D0 (da) | 1988-11-24 |
ZA888766B (en) | 1989-08-30 |
DK655288A (da) | 1989-08-04 |
CA1339802C (en) | 1998-04-07 |
JPH0686433B2 (ja) | 1994-11-02 |
IL88433A0 (en) | 1989-06-30 |
EP0318093A3 (en) | 1990-12-05 |
PT89075B (pt) | 1993-04-30 |
EP0318093A2 (en) | 1989-05-31 |
JPH02138259A (ja) | 1990-05-28 |
AU2589688A (en) | 1989-06-01 |
NZ227036A (en) | 1991-10-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG3A | Patent granted, date of granting |
Effective date: 19921008 |
|
MM3A | Annulment or lapse |
Free format text: LAPSE DUE TO NON-PAYMENT OF FEES Effective date: 19940430 |