PT815138E - Substituto sanguineo de hemoglobina polimerizada estavel - Google Patents

Substituto sanguineo de hemoglobina polimerizada estavel

Info

Publication number: PT815138E
Authority: PT; Portugal
Prior art keywords: hemoglobin; solution; blood; polymerized; blood cells
Prior art date: 1995-03-23

Application number

PT96909855T

Other languages

English (en)

Inventor

Maria S Gawryl

William R Light

Anthony J Laccetti

Robert A Houtchens

Carl W Rausch

Edward E Jacobs Jr

Original Assignee

Biopure Corp

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1995-03-23

Filing date

1996-03-22

Publication date

2002-12-31

1995-03-23 Priority claimed from US08/409,337 external-priority patent/US5854209A/en

1995-06-07 Priority claimed from US08/487,288 external-priority patent/US5895810A/en

1995-06-07 Priority claimed from US08/471,583 external-priority patent/US5691452A/en

1995-06-07 Priority claimed from US08/484,775 external-priority patent/US5955581A/en

1995-06-07 Priority claimed from US08/478,004 external-priority patent/US5753616A/en

1996-03-22 Application filed by Biopure Corp filed Critical Biopure Corp

2002-12-31 Publication of PT815138E publication Critical patent/PT815138E/pt

Classifications

- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B15/00—Layered products comprising a layer of metal
- B32B15/04—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material
- B32B15/08—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
- B32B15/09—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin comprising polyesters
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N1/00—Preservation of bodies of humans or animals, or parts thereof
- A01N1/10—Preservation of living parts
- A01N1/12—Chemical aspects of preservation
- A01N1/122—Preservation or perfusion media
- A01N1/126—Physiologically active agents, e.g. antioxidants or nutrients
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/41—Porphyrin- or corrin-ring-containing peptides
- A61K38/42—Haemoglobins; Myoglobins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P41/00—Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/08—Plasma substitutes; Perfusion solutions; Dialytics or haemodialytics; Drugs for electrolytic or acid-base disorders, e.g. hypovolemic shock
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B15/00—Layered products comprising a layer of metal
- B32B15/04—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material
- B32B15/08—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B15/00—Layered products comprising a layer of metal
- B32B15/04—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material
- B32B15/08—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
- B32B15/085—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin comprising polyolefins
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B15/00—Layered products comprising a layer of metal
- B32B15/04—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material
- B32B15/08—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
- B32B15/088—Layered products comprising a layer of metal comprising metal as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin comprising polyamides
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B15/00—Layered products comprising a layer of metal
- B32B15/20—Layered products comprising a layer of metal comprising aluminium or copper
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/06—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material
- B32B27/08—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/32—Layered products comprising a layer of synthetic resin comprising polyolefins
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/34—Layered products comprising a layer of synthetic resin comprising polyamides
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/36—Layered products comprising a layer of synthetic resin comprising polyesters
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/795—Porphyrin- or corrin-ring-containing peptides
- C07K14/805—Haemoglobins; Myoglobins
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
- A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
- A61J1/05—Containers specially adapted for medical or pharmaceutical purposes for collecting, storing or administering blood, plasma or medical fluids ; Infusion or perfusion containers
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2311/00—Metals, their alloys or their compounds
- B32B2311/02—Noble metals
- B32B2311/04—Gold
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2311/00—Metals, their alloys or their compounds
- B32B2311/02—Noble metals
- B32B2311/08—Silver
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2311/00—Metals, their alloys or their compounds
- B32B2311/24—Aluminium
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2323/00—Polyalkenes
- B32B2323/10—Polypropylene
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2367/00—Polyesters, e.g. PET, i.e. polyethylene terephthalate
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2377/00—Polyamides

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
General Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Organic Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Animal Behavior & Ethology (AREA)
Veterinary Medicine (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
Cardiology (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Diabetes (AREA)
Dentistry (AREA)
Vascular Medicine (AREA)
Gastroenterology & Hepatology (AREA)
Environmental Sciences (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Urology & Nephrology (AREA)
Genetics & Genomics (AREA)
Molecular Biology (AREA)
Surgery (AREA)
Biochemistry (AREA)
Hospice & Palliative Care (AREA)
Epidemiology (AREA)
Immunology (AREA)
Biophysics (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
External Artificial Organs (AREA)
Medicinal Preparation (AREA)
Solid-Sorbent Or Filter-Aiding Compositions (AREA)

PT96909855T 1995-03-23 1996-03-22 Substituto sanguineo de hemoglobina polimerizada estavel PT815138E (pt)

Applications Claiming Priority (7)

Application Number	Priority Date	Filing Date	Title
US08/409,337 US5854209A (en)	1995-03-23	1995-03-23	Method for oxygenating tissue having reduced red blood cell flow
US08/458,916 US5840852A (en)	1995-03-23	1995-06-02	Method for producing ultrapure stable polmerized hemoglobin blood-substitute
US47349795A	1995-06-07	1995-06-07
US08/487,288 US5895810A (en)	1995-03-23	1995-06-07	Stable polymerized hemoglobin and use thereof
US08/471,583 US5691452A (en)	1995-03-23	1995-06-07	Method for preserving a hemoglobin blood substitute
US08/484,775 US5955581A (en)	1986-11-10	1995-06-07	Method for producing a stable polymerized hemoglobin blood-substitute
US08/478,004 US5753616A (en)	1986-11-10	1995-06-07	Method for producing a stable polymerized hemoglobin blood-substitute

Publications (1)

Publication Number	Publication Date
PT815138E true PT815138E (pt)	2002-12-31

Family

ID=27569756

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PT96909855T PT815138E (pt)	1995-03-23	1996-03-22	Substituto sanguineo de hemoglobina polimerizada estavel

Country Status (11)

Country	Link
EP (5)	EP0815138B1 (pt)
JP (2)	JP4382877B2 (pt)
AT (2)	ATE447324T1 (pt)
AU (1)	AU705225B2 (pt)
CA (1)	CA2215697C (pt)
DE (1)	DE69623267T2 (pt)
DK (1)	DK0815138T3 (pt)
ES (1)	ES2179188T3 (pt)
NZ (1)	NZ305258A (pt)
PT (1)	PT815138E (pt)
WO (1)	WO1996029346A1 (pt)

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US6139878A (en) *	1998-04-27	2000-10-31	Aventis Behring, Llc	Method for preparing a diafiltered stabilized blood product
US6518010B2 (en)	2001-02-28	2003-02-11	Biopure Corporation	Use of defibrinated blood for manufacture of a hemoglobin-based oxygen carrier
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US7001715B2 (en)	2002-02-28	2006-02-21	Biopure Corporation	Purification of red blood cells by separation and diafiltration
AU2002245600B2 (en) *	2002-02-28	2006-12-21	Biopure Corporation	Purification of red blood cells by separation and diafiltration
TW200630385A (en) *	2005-02-09	2006-09-01	Vinnolit Gmbh & Co Kg	Process for the polymerisation of vinyl-containing monomers
WO2006108047A2 (en) *	2005-04-05	2006-10-12	Biopure Corporation	Oxygenated polymerized hemoglobin solutions and their uses for tissue visualization
JP4665791B2 (ja)	2005-04-15	2011-04-06	ニプロ株式会社	酸素運搬体の脱一酸化炭素化方法、脱一酸化炭素化された酸素運搬体、その医薬組成物及び脱一酸化炭素化装置
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CN102264410B (zh)	2008-12-01	2016-08-03	通用电气公司	用于从体液分离细胞的系统和方法
US8961787B2 (en)	2008-12-01	2015-02-24	General Electric Company	Systems and methods for processing complex biological materials
WO2011014855A2 (en) *	2009-07-31	2011-02-03	University Of Pittsburgh -Of The Commonwealth System Of Higher Education	Removal of oxygen from biological fluids
CA2781866C (en) *	2009-10-12	2019-12-03	New Health Sciences, Inc.	Blood storage bag system and depletion devices with oxygen and carbon dioxide depletion capabilities
US9199016B2 (en)	2009-10-12	2015-12-01	New Health Sciences, Inc.	System for extended storage of red blood cells and methods of use
US12089589B2 (en)	2009-10-12	2024-09-17	Hemanext Inc.	Irradiation of red blood cells and anaerobic storage
US11284616B2 (en)	2010-05-05	2022-03-29	Hemanext Inc.	Irradiation of red blood cells and anaerobic storage
CA2781874A1 (en)	2009-10-12	2011-04-21	New Health Sciences, Inc.	Oxygen depletion devices and methods for removing oxygen from red blood cells
US7989593B1 (en) *	2010-05-27	2011-08-02	Bing Lou Wong	Method for the preparation of a high-temperature stable oxygen-carrier-containing pharmaceutical composition and the use thereof
ES2959120T3 (es) *	2010-08-25	2024-02-20	Hemanext Inc	Método para potenciar la calidad y la supervivencia de glóbulos rojos durante el almacenamiento
PT3539381T (pt)	2010-11-05	2023-09-26	Hemanext Inc	Irradiação de glóbulos vermelhos e armazenamento anaeróbico
US8889830B2 (en)	2011-03-01	2014-11-18	Chuo University	Hemoglobin-albumin complex, and artificial plasma expander and artificial oxygen carrier containing the complex
US9067004B2 (en)	2011-03-28	2015-06-30	New Health Sciences, Inc.	Method and system for removing oxygen and carbon dioxide during red cell blood processing using an inert carrier gas and manifold assembly
PL2550973T3 (pl)	2011-07-23	2014-03-31	Sastomed Gmbh	Sprej do ran
AU2012294269B2 (en)	2011-08-10	2016-11-24	Hemanext Inc.	Integrated leukocyte, oxygen and/or CO2 depletion, and plasma separation filter device
WO2014134503A1 (en)	2013-02-28	2014-09-04	New Health Sciences, Inc.	Gas depletion and gas addition devices for blood treatment
US10279052B2 (en)	2014-02-07	2019-05-07	Pharmacophotonics, Inc.	Compositions and methods for measuring and expanding blood volume
WO2016145210A1 (en)	2015-03-10	2016-09-15	New Health Sciences, Inc.	Oxygen reduction disposable kits, devices and methods of use thereof
KR102661405B1 (ko)	2015-04-23	2024-04-25	헤마넥스트 인코포레이티드	혐기성 혈액 저장 용기
MX2017014812A (es)	2015-05-18	2018-05-11	New Health Sciences Inc	Metodos para el almacenamiento de sangre completa y composiciones de esta.
WO2017205590A2 (en)	2016-05-27	2017-11-30	New Health Sciences, Inc.	Anaerobic blood storage and pathogen inactivation method
EP3508214A4 (en)	2016-07-06	2020-05-13	Chuo University	Therapeutic agent for ischemic diseases
CN111315770A (zh) *	2017-09-12	2020-06-19	第二医疗技术联合公司	无内毒素血红蛋白类原料药的生产系统和方法及无内毒素蛋白的纯化方法
CN110128531B (zh) *	2019-05-17	2022-03-08	润方（北京）生物医药研究院有限公司	一种无碳酸酐酶血红蛋白的制备方法
CN114514034A (zh) *	2019-10-11	2022-05-17	医疗技术协会第二股份有限公司	稳定的血红蛋白组合物及其药物制剂
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1996
- 1996-03-22 PT PT96909855T patent/PT815138E/pt unknown
- 1996-03-22 EP EP96909855A patent/EP0815138B1/en not_active Expired - Lifetime
- 1996-03-22 WO PCT/US1996/004030 patent/WO1996029346A1/en active IP Right Grant
- 1996-03-22 AT AT00204281T patent/ATE447324T1/de not_active IP Right Cessation
- 1996-03-22 ES ES96909855T patent/ES2179188T3/es not_active Expired - Lifetime
- 1996-03-22 EP EP00204284A patent/EP1094079A3/en not_active Withdrawn
- 1996-03-22 AU AU53227/96A patent/AU705225B2/en not_active Ceased
- 1996-03-22 NZ NZ305258A patent/NZ305258A/xx unknown
- 1996-03-22 EP EP02075127A patent/EP1211261A3/en not_active Ceased
- 1996-03-22 CA CA002215697A patent/CA2215697C/en not_active Expired - Fee Related
- 1996-03-22 AT AT96909855T patent/ATE222926T1/de not_active IP Right Cessation
- 1996-03-22 JP JP52865796A patent/JP4382877B2/ja not_active Expired - Fee Related
- 1996-03-22 EP EP00204281A patent/EP1093720B1/en not_active Expired - Lifetime
- 1996-03-22 DK DK96909855T patent/DK0815138T3/da active
- 1996-03-22 DE DE69623267T patent/DE69623267T2/de not_active Expired - Lifetime
- 1996-03-22 EP EP00204276A patent/EP1094078A3/en not_active Withdrawn
2007
- 2007-03-19 JP JP2007071402A patent/JP2007260393A/ja active Pending

Also Published As

Publication number	Publication date
NZ305258A (en)	2000-10-27
EP1094079A2 (en)	2001-04-25
ES2179188T3 (es)	2003-01-16
ATE222926T1 (de)	2002-09-15
WO1996029346A1 (en)	1996-09-26
EP1093720A1 (en)	2001-04-25
JPH11502821A (ja)	1999-03-09
DK0815138T3 (da)	2002-12-23
DE69623267T2 (de)	2003-04-17
CA2215697A1 (en)	1996-09-26
AU705225B2 (en)	1999-05-20
EP1093720B1 (en)	2009-11-04
DE69623267D1 (de)	2002-10-02
EP0815138B1 (en)	2002-08-28
AU5322796A (en)	1996-10-08
EP1094078A3 (en)	2001-05-02
JP4382877B2 (ja)	2009-12-16
EP1094079A3 (en)	2001-05-02
ATE447324T1 (de)	2009-11-15
EP1211261A2 (en)	2002-06-05
EP0815138A1 (en)	1998-01-07
CA2215697C (en)	2009-08-18
EP1211261A3 (en)	2004-03-17
EP1094078A2 (en)	2001-04-25
JP2007260393A (ja)	2007-10-11

Publication	Publication Date	Title
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DK1121016T3 (da)	2003-02-24	Fremgangsmåde til konservering af et hæmoglobinbloderstatningspræparat
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