PT2966984T - Modificação de genes direcionada com utilização de reparação de genes mediada por oligonucleótidos - Google Patents
Modificação de genes direcionada com utilização de reparação de genes mediada por oligonucleótidosInfo
- Publication number
- PT2966984T PT2966984T PT147630727T PT14763072T PT2966984T PT 2966984 T PT2966984 T PT 2966984T PT 147630727 T PT147630727 T PT 147630727T PT 14763072 T PT14763072 T PT 14763072T PT 2966984 T PT2966984 T PT 2966984T
- Authority
- PT
- Portugal
- Prior art keywords
- efficiency
- oligonucleotide
- compositions
- methods
- repair
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
- C12N15/8213—Targeted insertion of genes into the plant genome by homologous recombination
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Plant Pathology (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
- Physiology (AREA)
- Botany (AREA)
- Developmental Biology & Embryology (AREA)
- Environmental Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201361801320P | 2013-03-15 | 2013-03-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
PT2966984T true PT2966984T (pt) | 2022-05-05 |
Family
ID=51538403
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PT147630727T PT2966984T (pt) | 2013-03-15 | 2014-03-14 | Modificação de genes direcionada com utilização de reparação de genes mediada por oligonucleótidos |
Country Status (24)
Country | Link |
---|---|
US (2) | US11434494B2 (pt) |
EP (1) | EP2966984B1 (pt) |
JP (1) | JP2016516408A (pt) |
KR (1) | KR102304487B1 (pt) |
CN (1) | CN105338805A (pt) |
AU (2) | AU2014233465A1 (pt) |
BR (1) | BR112015022848B1 (pt) |
CA (1) | CA2905135C (pt) |
CL (1) | CL2015002650A1 (pt) |
DK (1) | DK2966984T3 (pt) |
EA (1) | EA201591447A1 (pt) |
ES (1) | ES2912400T3 (pt) |
HK (1) | HK1220864A1 (pt) |
HR (1) | HRP20220521T1 (pt) |
HU (1) | HUE058351T2 (pt) |
IL (1) | IL241145B (pt) |
LT (1) | LT2966984T (pt) |
MY (1) | MY191390A (pt) |
PL (1) | PL2966984T3 (pt) |
PT (1) | PT2966984T (pt) |
RS (1) | RS63188B1 (pt) |
SI (1) | SI2966984T1 (pt) |
UA (1) | UA121099C2 (pt) |
WO (1) | WO2014144987A2 (pt) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT2966984T (pt) | 2013-03-15 | 2022-05-05 | Cibus Europe Bv | Modificação de genes direcionada com utilização de reparação de genes mediada por oligonucleótidos |
EP3325668B1 (en) * | 2015-07-23 | 2021-01-06 | Mayo Foundation for Medical Education and Research | Editing mitochondrial dna |
JP2017205104A (ja) | 2016-05-13 | 2017-11-24 | 株式会社カネカ | 植物のゲノム編集方法 |
US11499158B2 (en) | 2016-05-13 | 2022-11-15 | Kaneka Corporation | Method for modifying plant |
EP3456181A4 (en) | 2016-05-13 | 2019-12-25 | Kaneka Corporation | METHOD FOR PRODUCING A TRANSFORMED PLANT |
CN106755067A (zh) * | 2016-12-05 | 2017-05-31 | 天津吉诺沃生物科技有限公司 | 通过瞬时表达对植物基因进行定点插入的方法及获得的瞬时表达细胞、组织和突变植株 |
US11859219B1 (en) | 2016-12-30 | 2024-01-02 | Flagship Pioneering Innovations V, Inc. | Methods of altering a target nucleotide sequence with an RNA-guided nuclease and a single guide RNA |
Family Cites Families (37)
Publication number | Priority date | Publication date | Assignee | Title |
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US5100792A (en) | 1984-11-13 | 1992-03-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues |
US4945050A (en) | 1984-11-13 | 1990-07-31 | Cornell Research Foundation, Inc. | Method for transporting substances into living cells and tissues and apparatus therefor |
US5024944A (en) | 1986-08-04 | 1991-06-18 | Lubrizol Genetics, Inc. | Transformation, somatic embryogenesis and whole plant regeneration method for Glycine species |
US5008200A (en) | 1988-05-08 | 1991-04-16 | United Agriseeds, Inc. | Propagating multiple whole fertile plants from immature leguminous |
US5302523A (en) | 1989-06-21 | 1994-04-12 | Zeneca Limited | Transformation of plant cells |
US5550318A (en) | 1990-04-17 | 1996-08-27 | Dekalb Genetics Corporation | Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof |
US5484956A (en) | 1990-01-22 | 1996-01-16 | Dekalb Genetics Corporation | Fertile transgenic Zea mays plant comprising heterologous DNA encoding Bacillus thuringiensis endotoxin |
US5204253A (en) | 1990-05-29 | 1993-04-20 | E. I. Du Pont De Nemours And Company | Method and apparatus for introducing biological substances into living cells |
DE4216134A1 (de) | 1991-06-20 | 1992-12-24 | Europ Lab Molekularbiolog | Synthetische katalytische oligonukleotidstrukturen |
IT230274Y1 (it) | 1993-06-11 | 1999-06-02 | Silc Spa | Pannolone assorbente sagomato per incontinenza |
ES2149962T3 (es) | 1993-12-09 | 2000-11-16 | Univ Jefferson | Compuestos y metodos para mutaciones dirigidas al sitio en celulas eucarioticas. |
DE59510742D1 (de) | 1994-04-27 | 2003-08-14 | Novartis Ag | Nukleoside und Oligonukleotide mit 2'-Ethergruppen |
US5780296A (en) | 1995-01-17 | 1998-07-14 | Thomas Jefferson University | Compositions and methods to promote homologous recombination in eukaryotic cells and organisms |
US5888983A (en) | 1996-05-01 | 1999-03-30 | Thomas Jefferson University | Method and oligonucleobase compounds for curing diseases caused by mutations |
US5760012A (en) | 1996-05-01 | 1998-06-02 | Thomas Jefferson University | Methods and compounds for curing diseases caused by mutations |
US5731181A (en) | 1996-06-17 | 1998-03-24 | Thomas Jefferson University | Chimeric mutational vectors having non-natural nucleotides |
CN1268186A (zh) | 1997-04-30 | 2000-09-27 | 明尼苏达大学评议会 | 重组诱发剂寡核碱基校正肝细胞遗传损害的体内应用 |
US6524613B1 (en) | 1997-04-30 | 2003-02-25 | Regents Of The University Of Minnesota | Hepatocellular chimeraplasty |
JP2001512687A (ja) | 1997-08-05 | 2001-08-28 | キメラジェン,インコーポレーテッド | 植物に局在性遺伝子変化を生じさせるための混合二本鎖オリゴヌクレオチドの使用 |
US6004804A (en) | 1998-05-12 | 1999-12-21 | Kimeragen, Inc. | Non-chimeric mutational vectors |
US6010907A (en) | 1998-05-12 | 2000-01-04 | Kimeragen, Inc. | Eukaryotic use of non-chimeric mutational vectors |
US6271360B1 (en) | 1999-08-27 | 2001-08-07 | Valigen (Us), Inc. | Single-stranded oligodeoxynucleotide mutational vectors |
AR025996A1 (es) | 1999-10-07 | 2002-12-26 | Valigen Us Inc | Plantas no transgenicas resistentes a los herbicidas. |
EP1152058A1 (en) * | 2000-05-03 | 2001-11-07 | Institut Curie | Methods and compositions for effecting homologous recombination |
AU2002322435A1 (en) | 2001-08-09 | 2003-02-24 | Cibus Genetics | Non-transgenic herbicide resistant plants |
US20090263900A1 (en) * | 2008-04-14 | 2009-10-22 | Sangamo Biosciences, Inc. | Linear donor constructs for targeted integration |
BR122018070230B1 (pt) | 2007-10-05 | 2023-01-10 | Cibus Europe B.V. | Método para produção de planta resistente à herbicida |
CA2710262C (en) * | 2007-12-21 | 2015-11-03 | Keygene N.V. | An improved mutagenesis method using polyethylene glycol mediated introduction of mutagenic nucleobases into plant protoplasts |
WO2011078662A1 (en) * | 2009-12-21 | 2011-06-30 | Keygene N.V. | Dsrna for improved genetic modification of plant dna |
US20110201118A1 (en) * | 2010-06-14 | 2011-08-18 | Iowa State University Research Foundation, Inc. | Nuclease activity of tal effector and foki fusion protein |
EP2596101B1 (en) * | 2010-07-23 | 2018-12-05 | Sigma-Aldrich Co., LLC | Genome editing using targeting endonucleases and single-stranded nucleic acids |
KR102068107B1 (ko) * | 2011-04-27 | 2020-01-20 | 아미리스 인코퍼레이티드 | 게놈 변형 방법 |
EP2732029B1 (en) | 2011-07-11 | 2019-01-16 | FUJIFILM Cellular Dynamics, Inc. | Methods for cell reprogramming and genome engineering |
US20160046961A1 (en) | 2012-05-25 | 2016-02-18 | Emmanuelle Charpentier | Methods and Compositions for RNA-Directed Target DNA Modification and For RNA-Directed Modulation of Transcription |
WO2014071006A1 (en) * | 2012-10-31 | 2014-05-08 | Cellectis | Coupling herbicide resistance with targeted insertion of transgenes in plants |
PT2966984T (pt) | 2013-03-15 | 2022-05-05 | Cibus Europe Bv | Modificação de genes direcionada com utilização de reparação de genes mediada por oligonucleótidos |
US9680858B1 (en) | 2013-09-09 | 2017-06-13 | BitSight Technologies, Inc. | Annotation platform for a security risk system |
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2014
- 2014-03-14 PT PT147630727T patent/PT2966984T/pt unknown
- 2014-03-14 ES ES14763072T patent/ES2912400T3/es active Active
- 2014-03-14 BR BR112015022848-8A patent/BR112015022848B1/pt active IP Right Grant
- 2014-03-14 CN CN201480024708.9A patent/CN105338805A/zh active Pending
- 2014-03-14 HR HRP20220521TT patent/HRP20220521T1/hr unknown
- 2014-03-14 EP EP14763072.7A patent/EP2966984B1/en active Active
- 2014-03-14 WO PCT/US2014/029621 patent/WO2014144987A2/en active Application Filing
- 2014-03-14 AU AU2014233465A patent/AU2014233465A1/en not_active Abandoned
- 2014-03-14 PL PL14763072T patent/PL2966984T3/pl unknown
- 2014-03-14 HU HUE14763072A patent/HUE058351T2/hu unknown
- 2014-03-14 IL IL241145A patent/IL241145B/en unknown
- 2014-03-14 LT LTEPPCT/US2014/029621T patent/LT2966984T/lt unknown
- 2014-03-14 CA CA2905135A patent/CA2905135C/en active Active
- 2014-03-14 RS RS20220373A patent/RS63188B1/sr unknown
- 2014-03-14 KR KR1020157026632A patent/KR102304487B1/ko active Active
- 2014-03-14 MY MYPI2015703120A patent/MY191390A/en unknown
- 2014-03-14 EA EA201591447A patent/EA201591447A1/ru unknown
- 2014-03-14 DK DK14763072.7T patent/DK2966984T3/da active
- 2014-03-14 US US14/777,410 patent/US11434494B2/en active Active
- 2014-03-14 SI SI201431952T patent/SI2966984T1/sl unknown
- 2014-03-14 JP JP2016503169A patent/JP2016516408A/ja active Pending
- 2014-03-14 UA UAA201508559A patent/UA121099C2/uk unknown
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2015
- 2015-09-11 CL CL2015002650A patent/CL2015002650A1/es unknown
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2016
- 2016-07-21 HK HK16108753.2A patent/HK1220864A1/zh unknown
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2020
- 2020-08-17 AU AU2020220059A patent/AU2020220059B2/en active Active
-
2022
- 2022-09-05 US US17/902,970 patent/US20230141977A1/en active Pending
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