MY191390A - Methods and compositions for increasing efficiency of increased efficiency of targeted gene modification using oligonucleotide-mediated gene repair - Google Patents

Methods and compositions for increasing efficiency of increased efficiency of targeted gene modification using oligonucleotide-mediated gene repair

Info

Publication number: MY191390A
Authority: MY; Malaysia
Prior art keywords: efficiency; oligonucleotide; compositions; methods; increased efficiency
Prior art date: 2013-03-15

Application number

MYPI2015703120A

Other languages

English (en)

Inventor

Peter R Beetham

Gregory F W Gocal

Christian Schopke

Noel Joy Sauer

James Pearce

Rosa E Segami

Jerry Mozoruk

Original Assignee

Cibus Us Llc

Cibus Europe Bv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2013-03-15

Filing date

2014-03-14

Publication date

2022-06-22

2014-03-14 Application filed by Cibus Us Llc, Cibus Europe Bv filed Critical Cibus Us Llc

2022-06-22 Publication of MY191390A publication Critical patent/MY191390A/en

Links

108090000623 proteins and genes Proteins 0.000 title abstract 4
108091034117 Oligonucleotide Proteins 0.000 title abstract 2
238000000034 method Methods 0.000 title abstract 2
238000012239 gene modification Methods 0.000 title 1
230000001404 mediated effect Effects 0.000 title 1
239000000203 mixture Substances 0.000 title 1
206010064571 Gene mutation Diseases 0.000 abstract 1
JLCPHMBAVCMARE-UHFFFAOYSA-N [3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[3-[[3-[[3-[[3-[[3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-[[5-(2-amino-6-oxo-1H-purin-9-yl)-3-hydroxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxyoxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(5-methyl-2,4-dioxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphoryl]oxy-5-(4-amino-2-oxopyrimidin-1-yl)oxolan-2-yl]methyl [5-(6-aminopurin-9-yl)-2-(hydroxymethyl)oxolan-3-yl] hydrogen phosphate Polymers Cc1cn(C2CC(OP(O)(=O)OCC3OC(CC3OP(O)(=O)OCC3OC(CC3O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c3nc(N)[nH]c4=O)C(COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3COP(O)(=O)OC3CC(OC3CO)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3ccc(N)nc3=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cc(C)c(=O)[nH]c3=O)n3cc(C)c(=O)[nH]c3=O)n3ccc(N)nc3=O)n3cc(C)c(=O)[nH]c3=O)n3cnc4c3nc(N)[nH]c4=O)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)n3cnc4c(N)ncnc34)O2)c(=O)[nH]c1=O JLCPHMBAVCMARE-UHFFFAOYSA-N 0.000 abstract 1
238000013459 approach Methods 0.000 abstract 1
230000004048 modification Effects 0.000 abstract 1
238000012986 modification Methods 0.000 abstract 1
230000008263 repair mechanism Effects 0.000 abstract 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
- C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
- C12N15/8201—Methods for introducing genetic material into plant cells, e.g. DNA, RNA, stable or transient incorporation, tissue culture methods adapted for transformation
- C12N15/8213—Targeted insertion of genes into the plant genome by homologous recombination

Landscapes

Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Genetics & Genomics (AREA)
Engineering & Computer Science (AREA)
Biomedical Technology (AREA)
Biotechnology (AREA)
Bioinformatics & Cheminformatics (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
General Engineering & Computer Science (AREA)
Zoology (AREA)
Wood Science & Technology (AREA)
Physics & Mathematics (AREA)
Cell Biology (AREA)
Plant Pathology (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Biochemistry (AREA)
General Health & Medical Sciences (AREA)
Microbiology (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
Physiology (AREA)
Botany (AREA)
Developmental Biology & Embryology (AREA)
Environmental Sciences (AREA)
Saccharide Compounds (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

MYPI2015703120A 2013-03-15 2014-03-14 Methods and compositions for increasing efficiency of increased efficiency of targeted gene modification using oligonucleotide-mediated gene repair MY191390A (en)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US201361801320P	2013-03-15	2013-03-15
PCT/US2014/029621 WO2014144987A2 (en)	2013-03-15	2014-03-14	Methods and compositions for increasing efficiency of increased efficiency of targeted gene modification using oligonucleotide-mediated gene repair

Publications (1)

Publication Number	Publication Date
MY191390A true MY191390A (en)	2022-06-22

Family

ID=51538403

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
MYPI2015703120A MY191390A (en)	2013-03-15	2014-03-14	Methods and compositions for increasing efficiency of increased efficiency of targeted gene modification using oligonucleotide-mediated gene repair

Country Status (24)

Country	Link
US (2)	US11434494B2 (pt)
EP (1)	EP2966984B1 (pt)
JP (1)	JP2016516408A (pt)
KR (1)	KR102304487B1 (pt)
CN (1)	CN105338805A (pt)
AU (2)	AU2014233465A1 (pt)
BR (1)	BR112015022848B1 (pt)
CA (1)	CA2905135C (pt)
CL (1)	CL2015002650A1 (pt)
DK (1)	DK2966984T3 (pt)
EA (1)	EA201591447A1 (pt)
ES (1)	ES2912400T3 (pt)
HK (1)	HK1220864A1 (pt)
HR (1)	HRP20220521T1 (pt)
HU (1)	HUE058351T2 (pt)
IL (1)	IL241145B (pt)
LT (1)	LT2966984T (pt)
MY (1)	MY191390A (pt)
PL (1)	PL2966984T3 (pt)
PT (1)	PT2966984T (pt)
RS (1)	RS63188B1 (pt)
SI (1)	SI2966984T1 (pt)
UA (1)	UA121099C2 (pt)
WO (1)	WO2014144987A2 (pt)

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US11859219B1 (en)	2016-12-30	2024-01-02	Flagship Pioneering Innovations V, Inc.	Methods of altering a target nucleotide sequence with an RNA-guided nuclease and a single guide RNA

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2014
- 2014-03-14 RS RS20220373A patent/RS63188B1/sr unknown
- 2014-03-14 UA UAA201508559A patent/UA121099C2/uk unknown
- 2014-03-14 CN CN201480024708.9A patent/CN105338805A/zh active Pending
- 2014-03-14 LT LTEPPCT/US2014/029621T patent/LT2966984T/lt unknown
- 2014-03-14 EA EA201591447A patent/EA201591447A1/ru unknown
- 2014-03-14 PT PT147630727T patent/PT2966984T/pt unknown
- 2014-03-14 SI SI201431952T patent/SI2966984T1/sl unknown
- 2014-03-14 WO PCT/US2014/029621 patent/WO2014144987A2/en active Application Filing
- 2014-03-14 CA CA2905135A patent/CA2905135C/en active Active
- 2014-03-14 JP JP2016503169A patent/JP2016516408A/ja active Pending
- 2014-03-14 IL IL241145A patent/IL241145B/en unknown
- 2014-03-14 DK DK14763072.7T patent/DK2966984T3/da active
- 2014-03-14 EP EP14763072.7A patent/EP2966984B1/en active Active
- 2014-03-14 PL PL14763072T patent/PL2966984T3/pl unknown
- 2014-03-14 HR HRP20220521TT patent/HRP20220521T1/hr unknown
- 2014-03-14 AU AU2014233465A patent/AU2014233465A1/en not_active Abandoned
- 2014-03-14 US US14/777,410 patent/US11434494B2/en active Active
- 2014-03-14 MY MYPI2015703120A patent/MY191390A/en unknown
- 2014-03-14 ES ES14763072T patent/ES2912400T3/es active Active
- 2014-03-14 BR BR112015022848-8A patent/BR112015022848B1/pt active IP Right Grant
- 2014-03-14 KR KR1020157026632A patent/KR102304487B1/ko active Active
- 2014-03-14 HU HUE14763072A patent/HUE058351T2/hu unknown
2015
- 2015-09-11 CL CL2015002650A patent/CL2015002650A1/es unknown
2016
- 2016-07-21 HK HK16108753.2A patent/HK1220864A1/zh unknown
2020
- 2020-08-17 AU AU2020220059A patent/AU2020220059B2/en active Active
2022
- 2022-09-05 US US17/902,970 patent/US20230141977A1/en active Pending

Also Published As

Publication number	Publication date
DK2966984T3 (da)	2022-04-25
SI2966984T1 (sl)	2022-06-30
AU2020220059B2 (en)	2023-06-15
WO2014144987A2 (en)	2014-09-18
LT2966984T (lt)	2022-05-25
HK1220864A1 (zh)	2017-05-19
UA121099C2 (uk)	2020-04-10
ES2912400T3 (es)	2022-05-25
US11434494B2 (en)	2022-09-06
CA2905135C (en)	2022-10-25
AU2020220059A1 (en)	2020-09-03
EA201591447A1 (ru)	2016-05-31
HUE058351T2 (hu)	2022-07-28
NZ711146A (en)	2021-08-27
RS63188B1 (sr)	2022-06-30
EP2966984A4 (en)	2016-09-21
EP2966984A2 (en)	2016-01-20
BR112015022848B1 (pt)	2022-10-11
CL2015002650A1 (es)	2016-03-28
HRP20220521T1 (hr)	2022-06-10
US20230141977A1 (en)	2023-05-11
BR112015022848A2 (pt)	2017-11-07
JP2016516408A (ja)	2016-06-09
KR20150132202A (ko)	2015-11-25
IL241145A0 (en)	2015-11-30
US20160304892A1 (en)	2016-10-20
AU2014233465A1 (en)	2015-09-03
EP2966984B1 (en)	2022-03-02
CA2905135A1 (en)	2014-09-18
PT2966984T (pt)	2022-05-05
KR102304487B1 (ko)	2021-09-24
CN105338805A (zh)	2016-02-17
WO2014144987A3 (en)	2014-12-04
PL2966984T3 (pl)	2022-06-13
IL241145B (en)	2022-07-01

Publication	Publication Date	Title
MY183741A (en)	2021-03-10	Methods and compositions for increasing efficiency of targeted gene modification using oligonucleotide-mediated gene repair
MY191390A (en)	2022-06-22	Methods and compositions for increasing efficiency of increased efficiency of targeted gene modification using oligonucleotide-mediated gene repair
IN2014DN09261A (pt)	2015-07-10
PH12018501376A1 (en)	2019-11-11	Processing biomass and energy
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BR112015021579A2 (pt)	2017-10-10	manipulação de genes phb para acúlumo e produção de biomassa de planta
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