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PT2895188T - Etanercept dobrado corretamente de pureza elevada e rendimento excelente - Google Patents

Etanercept dobrado corretamente de pureza elevada e rendimento excelente

Info

Publication number
PT2895188T
PT2895188T PT138380167T PT13838016T PT2895188T PT 2895188 T PT2895188 T PT 2895188T PT 138380167 T PT138380167 T PT 138380167T PT 13838016 T PT13838016 T PT 13838016T PT 2895188 T PT2895188 T PT 2895188T
Authority
PT
Portugal
Prior art keywords
high purity
correctly folded
excellent yield
folded etanercept
etanercept
Prior art date
Application number
PT138380167T
Other languages
English (en)
Inventor
Arakawa Tsutomu
Farrar Douglas
Original Assignee
Coherus Biosciences Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=50233493&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PT2895188(T) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Coherus Biosciences Inc filed Critical Coherus Biosciences Inc
Publication of PT2895188T publication Critical patent/PT2895188T/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/241—Tumor Necrosis Factors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A61P17/06—Antipsoriatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P19/00—Drugs for skeletal disorders
    • A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/165—Extraction; Separation; Purification by chromatography mixed-mode chromatography
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Analytical Chemistry (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Pain & Pain Management (AREA)
  • Dermatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicinal Preparation (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
PT138380167T 2012-09-11 2013-09-10 Etanercept dobrado corretamente de pureza elevada e rendimento excelente PT2895188T (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201261699552P 2012-09-11 2012-09-11

Publications (1)

Publication Number Publication Date
PT2895188T true PT2895188T (pt) 2018-02-08

Family

ID=50233493

Family Applications (1)

Application Number Title Priority Date Filing Date
PT138380167T PT2895188T (pt) 2012-09-11 2013-09-10 Etanercept dobrado corretamente de pureza elevada e rendimento excelente

Country Status (33)

Country Link
US (6) US20140072560A1 (pt)
EP (1) EP2895188B1 (pt)
JP (3) JP2015533797A (pt)
KR (2) KR102133699B1 (pt)
CN (2) CN110051823A (pt)
AR (1) AR092532A1 (pt)
AU (2) AU2013315750B9 (pt)
BR (1) BR112015005161A2 (pt)
CA (1) CA2882551A1 (pt)
CL (1) CL2015000572A1 (pt)
CO (1) CO7400876A2 (pt)
CY (1) CY1120062T1 (pt)
DK (1) DK2895188T3 (pt)
DO (1) DOP2015000055A (pt)
EA (1) EA031324B1 (pt)
EC (1) ECSP15014138A (pt)
ES (1) ES2657377T3 (pt)
HR (1) HRP20180182T1 (pt)
HU (1) HUE036524T2 (pt)
IL (2) IL237311B (pt)
IN (1) IN2015KN00452A (pt)
LT (1) LT2895188T (pt)
MX (2) MX360044B (pt)
NO (1) NO2972131T3 (pt)
PE (2) PE20200607A1 (pt)
PL (1) PL2895188T3 (pt)
PT (1) PT2895188T (pt)
RS (1) RS57013B1 (pt)
SG (1) SG11201501460RA (pt)
SI (1) SI2895188T1 (pt)
SM (1) SMT201800163T1 (pt)
TW (2) TWI716649B (pt)
WO (1) WO2014043103A1 (pt)

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CN112876567A (zh) * 2019-11-29 2021-06-01 广东菲鹏制药股份有限公司 Fc融合蛋白及其纯化方法
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Also Published As

Publication number Publication date
HUE036524T2 (hu) 2018-07-30
LT2895188T (lt) 2018-04-10
EA201590542A1 (ru) 2015-07-30
IL267452B (en) 2021-05-31
KR102133699B1 (ko) 2020-07-14
AU2013315750B2 (en) 2018-07-12
IN2015KN00452A (pt) 2015-07-17
EA031324B1 (ru) 2018-12-28
MX2015003090A (es) 2015-07-14
HRP20180182T1 (hr) 2018-04-20
AU2013315750A1 (en) 2015-03-05
CL2015000572A1 (es) 2016-02-05
AU2013315750B9 (en) 2018-11-15
ECSP15014138A (es) 2016-01-29
MX2018012749A (es) 2020-11-12
SMT201800163T1 (it) 2018-05-02
US10954293B2 (en) 2021-03-23
PL2895188T3 (pl) 2018-06-29
IL237311A0 (en) 2015-04-30
US11001627B2 (en) 2021-05-11
AR092532A1 (es) 2015-04-22
TW201803593A (zh) 2018-02-01
EP2895188A1 (en) 2015-07-22
JP6913066B2 (ja) 2021-08-04
TWI716649B (zh) 2021-01-21
KR102250937B1 (ko) 2021-05-12
NO2972131T3 (pt) 2018-04-21
RS57013B1 (sr) 2018-05-31
US10947306B2 (en) 2021-03-16
EP2895188A4 (en) 2016-05-25
US20190300602A1 (en) 2019-10-03
TWI609877B (zh) 2018-01-01
CN104902914B (zh) 2019-01-01
MX360044B (es) 2018-10-19
KR20150056601A (ko) 2015-05-26
PE20200607A1 (es) 2020-03-10
JP2021100929A (ja) 2021-07-08
US20190300600A1 (en) 2019-10-03
WO2014043103A1 (en) 2014-03-20
CN110051823A (zh) 2019-07-26
US20190330325A1 (en) 2019-10-31
SI2895188T1 (en) 2018-05-31
ES2657377T3 (es) 2018-03-05
DOP2015000055A (es) 2015-04-30
US20140072560A1 (en) 2014-03-13
US20190300601A1 (en) 2019-10-03
CN104902914A (zh) 2015-09-09
CO7400876A2 (es) 2015-09-30
KR20200085937A (ko) 2020-07-15
CA2882551A1 (en) 2014-03-20
AU2018247244A1 (en) 2018-11-01
US20180037642A1 (en) 2018-02-08
TW201425331A (zh) 2014-07-01
US10954294B2 (en) 2021-03-23
IL237311B (en) 2019-07-31
BR112015005161A2 (pt) 2017-07-04
AU2018247244B2 (en) 2020-05-28
JP2019038817A (ja) 2019-03-14
CY1120062T1 (el) 2018-12-12
US10954295B2 (en) 2021-03-23
IL267452A (en) 2019-08-29
JP2015533797A (ja) 2015-11-26
DK2895188T3 (en) 2018-02-26
EP2895188B1 (en) 2017-11-15
PE20150996A1 (es) 2015-08-01
SG11201501460RA (en) 2015-04-29

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