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PL3137605T3 - Kompozycje i sposoby modulowania ekspresji białka angiopoetynopodobnego 3 - Google Patents

Kompozycje i sposoby modulowania ekspresji białka angiopoetynopodobnego 3

Info

Publication number
PL3137605T3
PL3137605T3 PL15786207T PL15786207T PL3137605T3 PL 3137605 T3 PL3137605 T3 PL 3137605T3 PL 15786207 T PL15786207 T PL 15786207T PL 15786207 T PL15786207 T PL 15786207T PL 3137605 T3 PL3137605 T3 PL 3137605T3
Authority
PL
Poland
Prior art keywords
expression
compositions
methods
modulating angiopoietin
angiopoietin
Prior art date
Application number
PL15786207T
Other languages
English (en)
Inventor
Thazha P. Prakash
Punit P. Seth
Eric E. Swayze
Susan M. Freier
Mark J. Graham
Rosanne M. Crooke
Original Assignee
Ionis Pharmaceuticals, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ionis Pharmaceuticals, Inc. filed Critical Ionis Pharmaceuticals, Inc.
Publication of PL3137605T3 publication Critical patent/PL3137605T3/pl

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
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    • A61K31/713—Double-stranded nucleic acids or oligonucleotides
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    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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    • C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
    • C12N15/1136—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against growth factors, growth regulators, cytokines, lymphokines or hormones
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    • C12N2310/32—Chemical structure of the sugar
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PL15786207T 2014-05-01 2015-05-01 Kompozycje i sposoby modulowania ekspresji białka angiopoetynopodobnego 3 PL3137605T3 (pl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US201461987467P 2014-05-01 2014-05-01
US201462049230P 2014-09-11 2014-09-11
EP15786207.9A EP3137605B1 (en) 2014-05-01 2015-05-01 Compositions and methods for modulating angiopoietin-like 3 expression
PCT/US2015/028837 WO2015168589A2 (en) 2014-05-01 2015-05-01 Compositions and methods for modulating angiopoietin-like 3 expression

Publications (1)

Publication Number Publication Date
PL3137605T3 true PL3137605T3 (pl) 2021-04-19

Family

ID=54354816

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Application Number Title Priority Date Filing Date
PL15786207T PL3137605T3 (pl) 2014-05-01 2015-05-01 Kompozycje i sposoby modulowania ekspresji białka angiopoetynopodobnego 3

Country Status (18)

Country Link
US (4) US9382540B2 (pl)
EP (2) EP3137605B1 (pl)
JP (4) JP2017521045A (pl)
KR (1) KR102356388B1 (pl)
CN (2) CN111961669A (pl)
AU (2) AU2015252895B2 (pl)
BR (2) BR112016024850B1 (pl)
CA (1) CA2946003A1 (pl)
DK (1) DK3137605T3 (pl)
ES (1) ES2844593T3 (pl)
HU (1) HUE052931T2 (pl)
IL (1) IL248269B (pl)
MX (2) MX382230B (pl)
PL (1) PL3137605T3 (pl)
PT (1) PT3137605T (pl)
RU (1) RU2734658C2 (pl)
SI (1) SI3137605T1 (pl)
WO (1) WO2015168589A2 (pl)

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