PL2190837T3 - Pochodne 4-pirymidynosulfamidu - Google Patents

Pochodne 4-pirymidynosulfamidu

Info

Publication number: PL2190837T3
Authority: PL; Poland
Prior art keywords: sulfamide derivatives; pyrimidine; pyrimidine sulfamide; derivatives; sulfamide
Prior art date: 2007-08-17

Application number

PL08807330T

Other languages

English (en)

Inventor

Martin Bolli

Christoph Boss

Alexander Treiber

Original Assignee

Idorsia Pharmaceuticals Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2007-08-17

Filing date

2008-08-15

Publication date

2013-01-31

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=40140023&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=PL2190837(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2008-08-15 Application filed by Idorsia Pharmaceuticals Ltd filed Critical Idorsia Pharmaceuticals Ltd

2013-01-31 Publication of PL2190837T3 publication Critical patent/PL2190837T3/pl

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/08—Drugs for disorders of the urinary system of the prostate
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/04—Drugs for skeletal disorders for non-specific disorders of the connective tissue
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
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- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
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- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/02—Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Public Health (AREA)
General Health & Medical Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Medicinal Chemistry (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Cardiology (AREA)
Diabetes (AREA)
Biomedical Technology (AREA)
Heart & Thoracic Surgery (AREA)
Hematology (AREA)
Neurosurgery (AREA)
Neurology (AREA)
Pulmonology (AREA)
Immunology (AREA)
Urology & Nephrology (AREA)
Pain & Pain Management (AREA)
Obesity (AREA)
Ophthalmology & Optometry (AREA)
Hospice & Palliative Care (AREA)
Oncology (AREA)
Communicable Diseases (AREA)
Endocrinology (AREA)
Psychiatry (AREA)
Transplantation (AREA)
Vascular Medicine (AREA)
Rheumatology (AREA)
Emergency Medicine (AREA)
Gynecology & Obstetrics (AREA)
Reproductive Health (AREA)
Physical Education & Sports Medicine (AREA)

PL08807330T 2007-08-17 2008-08-15 Pochodne 4-pirymidynosulfamidu PL2190837T3 (pl)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
IB2007053292		2007-08-17
IB2008052571		2008-06-26
EP08807330A EP2190837B1 (en)	2007-08-17	2008-08-15	4-pyrimidinesulfamide derivative
PCT/IB2008/053282 WO2009024906A1 (en)	2007-08-17	2008-08-15	4-pyrimidinesulfamide derivative

Publications (1)

Publication Number	Publication Date
PL2190837T3 true PL2190837T3 (pl)	2013-01-31

Family

ID=40140023

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
PL08807330T PL2190837T3 (pl)	2007-08-17	2008-08-15	Pochodne 4-pirymidynosulfamidu

Country Status (31)

Country	Link
US (1)	US8324232B2 (pl)
EP (1)	EP2190837B1 (pl)
JP (1)	JP5323075B2 (pl)
KR (1)	KR101528946B1 (pl)
CN (1)	CN101772494B (pl)
AR (1)	AR070018A1 (pl)
AU (1)	AU2008290234B2 (pl)
BR (1)	BRPI0815360B8 (pl)
CA (1)	CA2695511C (pl)
CY (1)	CY1113255T1 (pl)
DK (1)	DK2190837T3 (pl)
ES (1)	ES2394584T3 (pl)
FI (1)	FIC20240041I1 (pl)
FR (1)	FR24C1047I1 (pl)
HK (1)	HK1144196A1 (pl)
HR (1)	HRP20120878T1 (pl)
HU (1)	HUS2400041I1 (pl)
IL (1)	IL203936A (pl)
MA (1)	MA31702B1 (pl)
MX (1)	MX2010001837A (pl)
MY (1)	MY152281A (pl)
NL (1)	NL301304I2 (pl)
NO (1)	NO2024053I1 (pl)
NZ (1)	NZ583990A (pl)
PL (1)	PL2190837T3 (pl)
PT (1)	PT2190837E (pl)
RU (1)	RU2485116C2 (pl)
SI (1)	SI2190837T1 (pl)
TW (1)	TWI411437B (pl)
WO (1)	WO2009024906A1 (pl)
ZA (1)	ZA201001872B (pl)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
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EP2907811A1 (en) *	2014-02-14	2015-08-19	Actelion Pharmaceuticals Ltd.	Process for manufacturing pyrimidine sulfamide derivatives
WO2017093903A1 (en) *	2015-11-30	2017-06-08	Laurus Labs Private Limited	An improved process for the preparation of macitentan
WO2017191565A1 (en) *	2016-05-04	2017-11-09	Shilpa Medicare Limited	Process for preparation of macitentan
EP3658140A1 (en) *	2017-02-27	2020-06-03	Idorsia Pharmaceuticals Ltd	Combinations of a 4-pyrimidinesulfamide derivative with active ingredients for the treatment of endothelin related diseases
US12144811B2 (en) *	2017-11-30	2024-11-19	Idorsia Pharmaceuticals Ltd	Combination of a 4-pyrimidinesulfamide derivative with an SGLT-2 inhibitor for the treatment of endothelin related diseases
CN108997223B (zh) *	2018-08-09	2020-06-30	浙江先锋科技股份有限公司	5-(4-溴苯基)-4，6-二氯嘧啶的制备方法
TWI841649B (zh)	2018-12-21	2024-05-11	瑞士商艾克泰聯製藥有限公司	用於治療肺動脈高血壓之醫藥組成物
TW202042818A (zh)	2019-01-25	2020-12-01	瑞士商艾克泰聯製藥有限公司	用於治療慢性血栓性肺高血壓之醫藥組成物
EP4056182A1 (en) *	2019-11-07	2022-09-14	Crystal Pharmaceutical (Suzhou) Co., Ltd.	Crystal form of aprocitentan, preparation method therefor and use thereof
US20230167090A1 (en)	2020-05-21	2023-06-01	Teva Pharmaceuticals International Gmbh	Solid state forms of aprocitentan and process for preparation thereof
WO2023111797A1 (en) *	2021-12-17	2023-06-22	Janssen Biotech, Inc.	Pyrimidine sulfamide derivatives and process for manufacturing them
CN119255805A (zh)	2022-05-22	2025-01-03	爱杜西亚药品有限公司	用于治疗高血压的阿普昔腾坦
KR20250019676A (ko)	2022-05-25	2025-02-10	이도르시아 파마슈티컬스 리미티드	소듐 (5-(4-브로모페닐)-6-(2-((5-브로모피리미딘-2-일)옥시)에톡시)피리미딘-4-일)(술파모일)아미드의 결정질 형태

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KR20030041577A (ko)	2001-11-20	2003-05-27	디디에스텍주식회사	난용성 약물과 치환된 시클로덱스트린을 함유하는고체분산체 및 이를 함유하는 약제학적 조성물
EP1480679B1 (en)	2002-02-26	2007-05-23	Astrazeneca AB	Pharmaceutical formulation of iressa comprising a water-soluble cellulose derivative
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AU2004216258B2 (en)	2003-02-25	2006-10-19	Eli Lilly And Company	Crystalline non-solvated 1-(4-(2-piperidinylethoxy)phenoxy)-2-(4-methanesulfonylphenyl)-6-hydroxynaphthalene hydrochloride
MY151003A (en) *	2005-09-12	2014-03-31	Actelion Pharmaceuticals Ltd	Stable pharmaceutical composition comprising a pyrimidine-sulfamide
AR062501A1 (es)	2006-08-29	2008-11-12	Actelion Pharmaceuticals Ltd	Composiciones terapeuticas
AU2009215329B2 (en)	2008-02-20	2014-08-21	Actelion Pharmaceuticals Ltd	Combination comprising paclitaxel for treating ovarian cancer
PT2315587T (pt)	2008-08-13	2018-01-31	Actelion Pharmaceuticals Ltd	Produto que contém macitentan, composição farmacêutica que o contém e uso de macitentan

2008
- 2008-02-07 MX MX2010001837A patent/MX2010001837A/es active IP Right Grant
- 2008-08-14 AR ARP080103552A patent/AR070018A1/es not_active Application Discontinuation
- 2008-08-15 PL PL08807330T patent/PL2190837T3/pl unknown
- 2008-08-15 US US12/673,413 patent/US8324232B2/en active Active
- 2008-08-15 MY MYPI20100680 patent/MY152281A/en unknown
- 2008-08-15 CN CN2008801016796A patent/CN101772494B/zh active Active
- 2008-08-15 PT PT08807330T patent/PT2190837E/pt unknown
- 2008-08-15 WO PCT/IB2008/053282 patent/WO2009024906A1/en active Application Filing
- 2008-08-15 NZ NZ583990A patent/NZ583990A/en unknown
- 2008-08-15 DK DK08807330.9T patent/DK2190837T3/da active
- 2008-08-15 KR KR1020107004945A patent/KR101528946B1/ko active IP Right Grant
- 2008-08-15 BR BRPI0815360A patent/BRPI0815360B8/pt active IP Right Grant
- 2008-08-15 ES ES08807330T patent/ES2394584T3/es active Active
- 2008-08-15 AU AU2008290234A patent/AU2008290234B2/en active Active
- 2008-08-15 TW TW097131323A patent/TWI411437B/zh active
- 2008-08-15 CA CA2695511A patent/CA2695511C/en active Active
- 2008-08-15 RU RU2010109543/04A patent/RU2485116C2/ru active
- 2008-08-15 JP JP2010520674A patent/JP5323075B2/ja active Active
- 2008-08-15 EP EP08807330A patent/EP2190837B1/en active Active
- 2008-08-15 SI SI200830785T patent/SI2190837T1/sl unknown
2010
- 2010-02-14 IL IL203936A patent/IL203936A/en active IP Right Grant
- 2010-03-12 MA MA32692A patent/MA31702B1/fr unknown
- 2010-03-16 ZA ZA2010/01872A patent/ZA201001872B/en unknown
- 2010-11-12 HK HK10110542.0A patent/HK1144196A1/xx unknown
2012
- 2012-10-25 CY CY20121101015T patent/CY1113255T1/el unknown
- 2012-10-30 HR HRP20120878AT patent/HRP20120878T1/hr unknown
2024
- 2024-11-27 HU HUS2400041C patent/HUS2400041I1/hu unknown
- 2024-12-02 FI FIC20240041C patent/FIC20240041I1/fi unknown
- 2024-12-03 NO NO2024053C patent/NO2024053I1/no unknown
- 2024-12-05 FR FR24C1047C patent/FR24C1047I1/fr active Active
- 2024-12-10 NL NL301304C patent/NL301304I2/nl unknown

Also Published As

Publication number	Publication date
BRPI0815360A8 (pt)	2017-12-26
KR20100052517A (ko)	2010-05-19
JP2010536742A (ja)	2010-12-02
NZ583990A (en)	2012-06-29
AU2008290234A1 (en)	2009-02-26
CA2695511C (en)	2015-11-03
DK2190837T3 (da)	2012-10-08
HK1144196A1 (en)	2011-02-02
FIC20240041I1 (fi)	2024-12-02
NO2024053I1 (no)	2024-12-03
CN101772494A (zh)	2010-07-07
PT2190837E (pt)	2012-10-31
BRPI0815360B1 (pt)	2018-12-04
CA2695511A1 (en)	2009-02-26
TW200927122A (en)	2009-07-01
TWI411437B (zh)	2013-10-11
KR101528946B1 (ko)	2015-06-15
AU2008290234B2 (en)	2013-11-21
WO2009024906A1 (en)	2009-02-26
IL203936A (en)	2016-03-31
ZA201001872B (en)	2011-05-25
MA31702B1 (fr)	2010-09-01
HUS2400041I1 (hu)	2024-12-28
RU2485116C2 (ru)	2013-06-20
MX2010001837A (es)	2010-03-10
ES2394584T3 (es)	2013-02-04
JP5323075B2 (ja)	2013-10-23
CY1113255T1 (el)	2016-04-13
RU2010109543A (ru)	2011-09-27
HRP20120878T1 (hr)	2012-11-30
BRPI0815360B8 (pt)	2021-05-25
NL301304I2 (nl)	2024-12-19
EP2190837B1 (en)	2012-08-15
BRPI0815360A2 (pt)	2015-02-10
AR070018A1 (es)	2010-03-10
SI2190837T1 (sl)	2012-11-30
FR24C1047I1 (fr)	2025-01-10
EP2190837A1 (en)	2010-06-02
US8324232B2 (en)	2012-12-04
CN101772494B (zh)	2013-05-15
MY152281A (en)	2014-09-15
US20120142716A1 (en)	2012-06-07

Publication	Publication Date	Title
PL2190837T3 (pl)	2013-01-31	Pochodne 4-pirymidynosulfamidu
BRPI0813707A2 (pt)	2014-12-30	Derivados de pirimidinil-piridazinona
BRPI0820112A2 (pt)	2015-05-05	Derivados de isoxazol-piridina
BRPI0809992A2 (pt)	2014-10-14	Derivados de pirrolopirimidina
BRPI0820113A2 (pt)	2015-05-05	Derivados de isoxazolo-piridazina
DK2209786T3 (da)	2013-06-03	Pyrimidinsubstituerede purinderivater
BRPI0812155A2 (pt)	2019-09-24	derivados de espiroindolinona
BRPI0817935A2 (pt)	2015-04-07	Derivados de biarila
BRPI0813836A2 (pt)	2015-01-06	Derivados pirazólicos
ES2465673T9 (es)	2014-11-14	Derivados de pirimidina
BRPI0814236A2 (pt)	2015-01-06	Derivados de quinazolinamida
BRPI0812518A2 (pt)	2015-03-31	Derivados de indazolamida
BRPI0820649A2 (pt)	2015-06-16	Derivados de isoxazalo-pirazina
ATE475662T1 (de)	2010-08-15	Dihydropyrazolopyrimidinonderivate
BRPI0816461A2 (pt)	2015-03-24	Derivados fungicidas de 2-alquiltio-2-quinolonolóxi-acetamida
BRPI0818380A2 (pt)	2014-10-07	Combinação de herbicida-protetor
ATE483711T1 (de)	2010-10-15	Spiroindolinonderivate
ATE469905T1 (de)	2010-06-15	Pyridopyrimidinonderivate
ATE512135T1 (de)	2011-06-15	Spiroindolinonderivate
DK2035394T3 (da)	2009-10-05	2-pyrazincarboxamidderivater
BRPI0915991A2 (pt)	2019-09-24	derivados de sulfamida substituída
DK2152370T3 (da)	2011-08-15	Aryletherpyridazinonderivater
DK2132326T3 (da)	2012-12-17	Fremgangsmåder
BRPI0820779A2 (pt)	2015-06-16	Derivados de 4-amino-pirimidina
DK2086968T3 (da)	2012-03-19	5-hydroxymethyl-oxazolidin-2-on-derivater