NO20040632L - 2-amino-4,5-trisubstituerte tiazolylderivater. - Google Patents

2-amino-4,5-trisubstituerte tiazolylderivater.

Info

Publication number: NO20040632L
Authority: NO; Norway
Prior art keywords: amino; thiazolyl derivatives; trisubstituted; trisubstituted thiazolyl; derivatives
Prior art date: 2001-08-13

Application number

NO20040632A

Other languages

English (en)

Other versions

NO327409B1 (no

Inventor

Ludwig Paul Cooymans

Robert Jozef Maria Hendrickx

Guy Rosalia Eugene Van Lommen

Gustaaf Maria Boeckx

Erwin Coesemans

Christopher John Love

Nele Vandermaesen

Julien Georges Pierre-Ol Doyon

Jean-Pierre Andre Ma Bongaritz

Marcel Jozef Maria Van Der Aa

Peter Jacobus Johan Buijnsters

Original Assignee

Janssen Pharmaceutica Nv

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-08-13

Filing date

2004-02-12

Publication date

2004-03-11

2004-02-12 Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv

2004-03-11 Publication of NO20040632L publication Critical patent/NO20040632L/no

2009-06-22 Publication of NO327409B1 publication Critical patent/NO327409B1/no

Classifications

- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/425—Thiazoles
- A61K31/426—1,3-Thiazoles
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/38—Nitrogen atoms
- C07D277/42—Amino or imino radicals substituted by hydrocarbon or substituted hydrocarbon radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Pharmacology & Pharmacy (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Tropical Medicine & Parasitology (AREA)
Immunology (AREA)
Pain & Pain Management (AREA)
Rheumatology (AREA)
Epidemiology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Thiazole And Isothizaole Compounds (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

NO20040632A 2001-08-13 2004-02-12 2-amino-4,5-trisubstituerte tiazolylderivater. NO327409B1 (no)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP01203087		2001-08-13
PCT/EP2002/008955 WO2003015773A2 (en)	2001-08-13	2002-08-09	2-amino-4,5-trisubstituted thiazolyl derivatives and their use against autoimmune diseases

Publications (2)

Publication Number	Publication Date
NO20040632L true NO20040632L (no)	2004-03-11
NO327409B1 NO327409B1 (no)	2009-06-22

Family

ID=8180790

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NO20040632A NO327409B1 (no)	2001-08-13	2004-02-12	2-amino-4,5-trisubstituerte tiazolylderivater.

Country Status (21)

Country	Link
US (2)	US7232838B2 (no)
EP (1)	EP1418909B1 (no)
JP (1)	JP4388805B2 (no)
KR (2)	KR101034489B1 (no)
CN (1)	CN100496493C (no)
AU (1)	AU2002324045C1 (no)
BR (1)	BR0211887A (no)
CA (1)	CA2451980C (no)
EA (1)	EA007717B1 (no)
ES (1)	ES2407807T3 (no)
HK (1)	HK1069997A1 (no)
HR (1)	HRP20040097B1 (no)
HU (1)	HUP0401748A3 (no)
IL (2)	IL160329A0 (no)
MX (1)	MXPA04001399A (no)
NO (1)	NO327409B1 (no)
NZ (1)	NZ530950A (no)
PL (1)	PL368130A1 (no)
UA (1)	UA82176C2 (no)
WO (1)	WO2003015773A2 (no)
ZA (1)	ZA200401162B (no)

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TW200519106A (en) *	2003-05-02	2005-06-16	Novartis Ag	Organic compounds
AU2005209485A1 (en) *	2004-01-30	2005-08-11	Ab Science	2-(3-substituted-aryl)amino-4-aryl-thiazoles as tyrosine kinase inhibitors
SG159561A1 (en)	2005-05-09	2010-03-30	Achillion Pharmaceuticals Inc	Thiazole compounds and methods of use
WO2006128172A2 (en) *	2005-05-26	2006-11-30	Synta Pharmaceuticals Corp.	Method for treating b cell regulated autoimmune disorders
EA015034B1 (ru) *	2005-09-13	2011-04-29	Янссен Фармацевтика Н.В.	2-анилин-4-арилзамещенные тиазольные производные
CN101484433A (zh)	2006-02-15	2009-07-15	艾博特公司	新的乙酰辅酶a羧化酶(acc)抑制剂及其在糖尿病、肥胖症和代谢综合征中的应用
CN101384568B (zh) *	2006-02-15	2012-12-12	雅培制药有限公司	乙酰辅酶a羧化酶(acc)抑制剂及其在糖尿病、肥胖症和代谢综合征中的应用
AU2007223797A1 (en) *	2006-03-08	2007-09-13	Achillion Pharmaceuticals, Inc.	Substituted aminothiazole derivatives with anti-HCV activity
EP2402320A1 (en)	2006-03-31	2012-01-04	Novartis AG	Anorectic agents
CA2687817A1 (en)	2007-05-22	2008-12-04	Achillion Pharmaceuticals, Inc.	Heteroaryl substituted thiazoles
ES2617305T3 (es) *	2007-07-17	2017-06-16	Acea Biosciences, Inc.	Compuestos heterocíclicos y usos como agentes anticancerosos
AR066169A1 (es)	2007-09-28	2009-07-29	Novartis Ag	Derivados de benzo-imidazoles, utiles para trastornos asociados con la actividad de dgat
JO2784B1 (en)	2007-10-18	2014-03-15	شركة جانسين فارماسوتيكا ان. في	5,3,1 - Triazole substitute derivative
MX2010004177A (es)	2007-10-18	2010-05-03	Janssen Pharmaceutica Nv	1,2,4-triazoles trisustituidos.
KR20100093129A (ko)	2007-12-20	2010-08-24	노파르티스 아게	Ｐｉ３ 키나제 억제제로서 사용되는 티아졸 유도체
WO2009114552A1 (en) *	2008-03-10	2009-09-17	The Board Of Trustees Of The Leland Stanford Junior University	Heteroaryl compounds, compositions, and methods of use in cancer treatment
JP5383788B2 (ja)	2008-03-19	2014-01-08	ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ	ニコチン性アセチルコリン受容体モジュレーターとしての三置換された１，２，４−トリアゾール
AR071763A1 (es)	2008-05-09	2010-07-14	Janssen Pharmaceutica Nv	Pirazoles trisustituidos, composiciones farmaceuticas que los contienen, y usos de los mismos en el tratamiento de trastornos neurologicos y psiquiatricos
US8106209B2 (en) *	2008-06-06	2012-01-31	Achillion Pharmaceuticals, Inc.	Substituted aminothiazole prodrugs of compounds with anti-HCV activity
EP2306836B1 (en) *	2008-07-01	2016-09-07	PTC Therapeutics, Inc.	Bmi-1 protein expression modulators
UA104147C2 (uk) *	2008-09-10	2014-01-10	Новартис Аг	Похідна піролідиндикарбонової кислоти та її застосування у лікуванні проліферативних захворювань
TW201026693A (en) *	2008-10-01	2010-07-16	Synta Pharmaceuticals Corp	Compounds for inflammation and immune-related uses
US8293753B2 (en) *	2009-07-02	2012-10-23	Novartis Ag	Substituted 2-carboxamide cycloamino ureas
JP6240078B2 (ja) *	2011-10-04	2017-11-29	バルークエス．ブルームバーグインスティテュート	肝細胞癌を含む癌の阻害剤、および肝炎ウイルス複製の阻害剤としての置換アミノチアゾール
CN103159695B (zh) *	2011-12-08	2015-08-12	首都师范大学	可抑制hiv复制并对耐药hiv病毒株有效的噻唑类化合物及其制备方法和用途
CN102863435B (zh) *	2012-09-25	2015-02-18	盐城工学院	一种2-[[4-氟-3-(三氟甲基)苯基]氨基]-4-吡啶基-5-噻唑甲醛及其还原产物的制备方法
US9453002B2 (en)	2013-08-16	2016-09-27	Janssen Pharmaceutica Nv	Substituted imidazoles as N-type calcium channel blockers
US11072592B2 (en)	2015-02-27	2021-07-27	The Regents Of The University Of California	Small molecules that enable cartilage rejuvenation
KR20170001969U (ko)	2015-11-27	2017-06-07	주식회사 바이오해저드특수청소	조류 퇴치기
CN105524056A (zh) *	2016-01-05	2016-04-27	中山大学肿瘤防治中心	一种氨基噻唑化合物及其制备方法和应用

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US5000775A (en) *	1985-12-31	1991-03-19	Monsanto Company	2-amino-4,5-disubstituted-oxazole/thiazole compounds as herbicide antidotes
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2002
- 2002-08-09 KR KR1020107011315A patent/KR101034489B1/ko active IP Right Grant
- 2002-08-09 JP JP2003520732A patent/JP4388805B2/ja not_active Expired - Fee Related
- 2002-08-09 KR KR1020037017268A patent/KR100979988B1/ko active IP Right Grant
- 2002-08-09 BR BR0211887-4A patent/BR0211887A/pt not_active IP Right Cessation
- 2002-08-09 EP EP02758455A patent/EP1418909B1/en not_active Expired - Lifetime
- 2002-08-09 US US10/486,819 patent/US7232838B2/en not_active Expired - Lifetime
- 2002-08-09 ES ES02758455T patent/ES2407807T3/es not_active Expired - Lifetime
- 2002-08-09 AU AU2002324045A patent/AU2002324045C1/en not_active Ceased
- 2002-08-09 EA EA200400306A patent/EA007717B1/ru not_active IP Right Cessation
- 2002-08-09 IL IL16032902A patent/IL160329A0/xx unknown
- 2002-08-09 WO PCT/EP2002/008955 patent/WO2003015773A2/en active Application Filing
- 2002-08-09 MX MXPA04001399A patent/MXPA04001399A/es active IP Right Grant
- 2002-08-09 HU HU0401748A patent/HUP0401748A3/hu unknown
- 2002-08-09 CA CA2451980A patent/CA2451980C/en not_active Expired - Lifetime
- 2002-08-09 CN CNB028157990A patent/CN100496493C/zh not_active Expired - Fee Related
- 2002-08-09 NZ NZ530950A patent/NZ530950A/xx not_active IP Right Cessation
- 2002-08-09 PL PL02368130A patent/PL368130A1/xx not_active Application Discontinuation
- 2002-09-08 UA UA2004031904A patent/UA82176C2/uk unknown
2004
- 2004-01-29 HR HRP20040097AA patent/HRP20040097B1/hr not_active IP Right Cessation
- 2004-02-11 IL IL160329A patent/IL160329A/en active IP Right Grant
- 2004-02-12 ZA ZA2004/01162A patent/ZA200401162B/en unknown
- 2004-02-12 NO NO20040632A patent/NO327409B1/no not_active IP Right Cessation
2005
- 2005-04-01 HK HK05102761.8A patent/HK1069997A1/xx not_active IP Right Cessation
2007
- 2007-05-01 US US11/742,741 patent/US7803823B2/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
AU2002324045C1 (en)	2008-05-29
WO2003015773A3 (en)	2003-12-18
US20070203189A1 (en)	2007-08-30
KR100979988B1 (ko)	2010-09-03
UA82176C2 (en)	2008-03-25
KR20100076043A (ko)	2010-07-05
IL160329A (en)	2010-05-31
EP1418909A2 (en)	2004-05-19
CN1541097A (zh)	2004-10-27
HK1069997A1 (en)	2005-06-10
ES2407807T3 (es)	2013-06-14
HRP20040097A2 (en)	2004-06-30
KR20040031712A (ko)	2004-04-13
US7803823B2 (en)	2010-09-28
AU2002324045B2 (en)	2007-10-04
EP1418909B1 (en)	2013-02-20
CA2451980A1 (en)	2003-02-27
EA007717B1 (ru)	2006-12-29
ZA200401162B (en)	2005-07-27
JP4388805B2 (ja)	2009-12-24
CA2451980C (en)	2012-12-11
IL160329A0 (en)	2004-07-25
PL368130A1 (en)	2005-03-21
NO327409B1 (no)	2009-06-22
US20040254191A1 (en)	2004-12-16
CN100496493C (zh)	2009-06-10
EA200400306A1 (ru)	2004-08-26
HUP0401748A3 (en)	2011-03-28
HRP20040097B1 (hr)	2013-10-11
US7232838B2 (en)	2007-06-19
JP2005501099A (ja)	2005-01-13
NZ530950A (en)	2006-03-31
KR101034489B1 (ko)	2011-05-17
WO2003015773A2 (en)	2003-02-27
BR0211887A (pt)	2004-09-21
MXPA04001399A (es)	2004-05-27
HUP0401748A2 (hu)	2004-12-28

Publication	Publication Date	Title
NO20040632L (no)	2004-03-11	2-amino-4,5-trisubstituerte tiazolylderivater.
DE50210707D1 (de)	2007-09-27	Substituierte 2-pyridin-cyclohexan-1,4-diaminderivate
DK1529530T3 (da)	2006-11-13	Forbindelser, der påvirker glucokinase
NO20023516L (no)	2002-07-23	Antibakterielle 3-aminokinazolinon-2,4-dioner
NO20040654L (no)	2004-05-14	Gassmikrosfaere-liposomkompositter.
DE60129750D1 (de)	2007-09-13	Antiblend-, antibeschlagselement
NO20040387L (no)	2004-03-24	Nedihullsfrigjoringskopling.
DE60315471D1 (de)	2007-09-20	2,5-disubstituierte 3-mercaptopentansaure
ITMI20022183A1 (it)	2003-04-24	Cerniera.
BR0103827B1 (pt)	2012-08-21	cola - pds.
IS7131A (is)	2004-01-29	Nýjar 2,4-díamínóþíasól afleiður
ES1049973Y (es)	2002-06-01	Maqueta-belen plegable.
ES1050491Y (es)	2002-08-01	Chupete infantil.
BR8101236Y1 (pt)	2011-12-27	desensiladeira.
IS7299A (is)	2004-06-03	3,4-díhýdró-1H-ísókínólóín-2-ýl-afleiður
ES1057516Y (es)	2005-04-16	Pieza rodapie mejorada.
ES1050786Y (es)	2002-09-16	Monedero polivalente.
ITTO20010239V0 (it)	2001-12-21	Portamonete.
ITTO20010243U1 (it)	2003-06-30	Portamonete.
ES1048471Y (es)	2001-12-16	Pupitre plegable.
ES1048458Y (es)	2001-12-16	Estuche perfeccionado.
ES1049298Y (es)	2002-03-16	Embalaje-expositor.
ES1048703Y (es)	2002-02-01	Conversor.
ES1053113Y (es)	2003-07-01	Tenedor-expulsor.
ES1051741Y (es)	2003-02-01	Caja-envase.

Legal Events

Date	Code	Title	Description
2022-03-28	MM1K	Lapsed by not paying the annual fees