NL9002314A - Immunogene complexen, in het bijzonder iscoms. - Google Patents

Immunogene complexen, in het bijzonder iscoms. Download PDF

Info

Publication number: NL9002314A
Authority: NL; Netherlands
Prior art keywords: quil; fractions; iscom; immunogenic complex; saponin
Prior art date: 1990-10-23

Application number

NL9002314A

Other languages

English (en)

Dutch (nl)

Original Assignee

Nederlanden Staat

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1990-10-23

Filing date

1990-10-23

Publication date

1992-05-18

1990-10-23 Application filed by Nederlanden Staat filed Critical Nederlanden Staat

1990-10-23 Priority to NL9002314A priority Critical patent/NL9002314A/nl

1991-10-23 Priority to US08/039,294 priority patent/US5620690A/en

1991-10-23 Priority to DK91918619.7T priority patent/DK0555276T3/da

1991-10-23 Priority to PCT/NL1991/000211 priority patent/WO1992006710A1/en

1991-10-23 Priority to CA002094600A priority patent/CA2094600C/en

1991-10-23 Priority to AT91918619T priority patent/ATE127024T1/de

1991-10-23 Priority to DE69112634T priority patent/DE69112634T2/de

1991-10-23 Priority to ES91918619T priority patent/ES2075964T3/es

1991-10-23 Priority to EP91918619A priority patent/EP0555276B1/en

1992-05-18 Publication of NL9002314A publication Critical patent/NL9002314A/nl

1995-10-18 Priority to GR950402880T priority patent/GR3017778T3/el

Links

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Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/39—Medicinal preparations containing antigens or antibodies characterised by the immunostimulating additives, e.g. chemical adjuvants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
- C07H15/20—Carbocyclic rings
- C07H15/24—Condensed ring systems having three or more rings
- C07H15/256—Polyterpene radicals
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18411—Morbillivirus, e.g. Measles virus, canine distemper
- C12N2760/18422—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

Chemical & Material Sciences (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Organic Chemistry (AREA)
General Health & Medical Sciences (AREA)
Medicinal Chemistry (AREA)
Molecular Biology (AREA)
Genetics & Genomics (AREA)
Biochemistry (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biophysics (AREA)
Gastroenterology & Hepatology (AREA)
Veterinary Medicine (AREA)
Mycology (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Epidemiology (AREA)
Biotechnology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Microbiology (AREA)
Virology (AREA)
Immunology (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Peptides Or Proteins (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)

NL9002314A 1990-10-23 1990-10-23 Immunogene complexen, in het bijzonder iscoms. NL9002314A (nl)

Priority Applications (10)

Application Number	Priority Date	Filing Date	Title
NL9002314A NL9002314A (nl)	1990-10-23	1990-10-23	Immunogene complexen, in het bijzonder iscoms.
US08/039,294 US5620690A (en)	1990-10-23	1991-10-23	Immunogenic complexes
DK91918619.7T DK0555276T3 (da)	1990-10-23	1991-10-23	Immunogene komplekser, især iscomer
PCT/NL1991/000211 WO1992006710A1 (en)	1990-10-23	1991-10-23	Immunogenic complexes, in particular iscoms
CA002094600A CA2094600C (en)	1990-10-23	1991-10-23	Immunogenic complexes, in particular iscoms
AT91918619T ATE127024T1 (de)	1990-10-23	1991-10-23	Immunogene komplexe, insbesondere iscoms.
DE69112634T DE69112634T2 (de)	1990-10-23	1991-10-23	Immunogene komplexe, insbesondere iscoms.
ES91918619T ES2075964T3 (es)	1990-10-23	1991-10-23	Complejos inmunogenos, en particular iscomes.
EP91918619A EP0555276B1 (en)	1990-10-23	1991-10-23	Immunogenic complexes, in particular iscoms
GR950402880T GR3017778T3 (en)	1990-10-23	1995-10-18	Immunogenic complexes, in particular iscoms.

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
NL9002314		1990-10-23
NL9002314A NL9002314A (nl)	1990-10-23	1990-10-23	Immunogene complexen, in het bijzonder iscoms.

Publications (1)

Publication Number	Publication Date
NL9002314A true NL9002314A (nl)	1992-05-18

Family

ID=19857870

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
NL9002314A NL9002314A (nl)	1990-10-23	1990-10-23	Immunogene complexen, in het bijzonder iscoms.

Country Status (10)

Country	Link
US (1)	US5620690A (es)
EP (1)	EP0555276B1 (es)
AT (1)	ATE127024T1 (es)
CA (1)	CA2094600C (es)
DE (1)	DE69112634T2 (es)
DK (1)	DK0555276T3 (es)
ES (1)	ES2075964T3 (es)
GR (1)	GR3017778T3 (es)
NL (1)	NL9002314A (es)
WO (1)	WO1992006710A1 (es)

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CA2147480A1 (en) *	1992-10-30	1994-05-11	Kristian Dalsgard	Cultured cells of quillaja sp.
NL9301690A (nl) *	1993-08-12	1995-04-18	Seed Capital Investments	Verbindingen met adjuvans-activiteit.
AU1077795A (en) *	1993-09-30	1995-04-18	Seed Capital Investments (Sci) B.V.	Compounds with adjuvant activity
AUPM500494A0 (en) *	1994-04-12	1994-05-05	Minister For Agriculture & Rural Affairs For The State Of New South Wales, The	Composition for use in increasing mucosal immunity
AUPM873294A0 (en) *	1994-10-12	1994-11-03	Csl Limited	Saponin preparations and use thereof in iscoms
GB9620795D0 (en) *	1996-10-05	1996-11-20	Smithkline Beecham Plc	Vaccines
UA56132C2 (uk) *	1995-04-25	2003-05-15	Смітклайн Бічем Байолоджікалс С.А.	Композиція вакцини (варіанти), спосіб стабілізації qs21 відносно гідролізу (варіанти), спосіб приготування композиції вакцини
SE9600648D0 (sv) *	1996-02-21	1996-02-21	Bror Morein	Receptorbimdande enhet
AUPO517897A0 (en) *	1997-02-19	1997-04-11	Csl Limited	Chelating immunostimulating complexes
ES2327693T3 (es) *	1997-08-29	2009-11-02	Antigenics Inc.	Composiciones que comprenden el adyvante qs-21 y polisorbato o ciclodextrina excipiente.
GB9817052D0 (en)	1998-08-05	1998-09-30	Smithkline Beecham Biolog	Vaccine
ATE409495T1 (de)	2001-04-04	2008-10-15	Nordic Vaccine Technology As	Polynukleotide-bindende komplexe die sterolen und saponine enthalten
US7713942B2 (en)	2001-04-04	2010-05-11	Nordic Vaccine Technology A/S	Cage-like microparticle complexes comprising sterols and saponins for delivery of polynucleotides
SE0202110D0 (sv)	2002-07-05	2002-07-05	Isconova Ab	Iscom preparation and use thereof
WO2004030696A2 (en) *	2002-10-02	2004-04-15	Nordic Vaccine Technology A/S	Composition for vaccination
SE0300795D0 (sv)	2003-03-24	2003-03-24	Isconova Ab	Composition comprising iscom particles and live micro-organisms
SE0301998D0 (sv) *	2003-07-07	2003-07-07	Isconova Ab	Quil A fraction with low toxicity and use thereof
US8007806B2 (en) *	2005-01-20	2011-08-30	Isconova Ab	Vaccine composition comprising a fibronectin binding protein or a fibronectin binding peptide
CA2604474C (en) *	2005-04-14	2012-07-17	Hirotaka Tanaka	Hemoglobin derivative measurement method, and reagent composition, measurement kit, analysis device and analysis system for use in the method
MX2011007494A (es)	2009-01-13	2011-08-12	Transgene Sa	Uso de una fraccion de la mitocondria de acidos nucleicos de saccharomyces cerevisiae para la estimulacion inmune.
US10047116B2 (en)	2011-10-03	2018-08-14	Mx Adjuvac Ab	Nanoparticles, process for preparation and use thereof as carrier for amphipatic and hydrophobic molecules in fields of medicine including cancer treatment and food related compounds
AU2016315478B2 (en)	2015-09-03	2023-07-13	Novavax, Inc.	Vaccine compositions having improved stability and immunogenicity
CN111148509A (zh)	2017-07-24	2020-05-12	诺瓦瓦克斯股份有限公司	治疗呼吸系统疾病的方法和组合物
US11278612B2 (en)	2018-03-19	2022-03-22	Novavax, Inc.	Multivalent influenza nanoparticle vaccines
US10953089B1 (en)	2020-01-27	2021-03-23	Novavax, Inc.	Coronavirus vaccine formulations

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Publication number	Priority date	Publication date	Assignee	Title
SE8205892D0 (sv) *	1982-10-18	1982-10-18	Bror Morein	Immunogent membranproteinkomplex, sett for framstellning och anvendning derav som immunstimulerande medel och sasom vaccin
SE8405493D0 (sv) *	1984-11-01	1984-11-01	Bror Morein	Immunogent komplex samt sett for framstellning derav och anvendning derav som immunstimulerande medel
ATE71303T1 (de) *	1986-01-14	1992-01-15	Nederlanden Staat	Verfahren zur herstellung immunologischer komplexe und diese enthaltende pharmazeutische zusammensetzung.
US5057540A (en) *	1987-05-29	1991-10-15	Cambridge Biotech Corporation	Saponin adjuvant
CA1331443C (en) *	1987-05-29	1994-08-16	Charlotte A. Kensil	Saponin adjuvant
NZ230747A (en) *	1988-09-30	1992-05-26	Bror Morein	Immunomodulating matrix comprising a complex of at least one lipid and at least one saponin; certain glycosylated triterpenoid saponins derived from quillaja saponaria molina
US4981684A (en) *	1989-10-24	1991-01-01	Coopers Animal Health Limited	Formation of adjuvant complexes
US5273965A (en) *	1992-07-02	1993-12-28	Cambridge Biotech Corporation	Methods for enhancing drug delivery with modified saponins

1990
- 1990-10-23 NL NL9002314A patent/NL9002314A/nl not_active Application Discontinuation
1991
- 1991-10-23 AT AT91918619T patent/ATE127024T1/de not_active IP Right Cessation
- 1991-10-23 CA CA002094600A patent/CA2094600C/en not_active Expired - Lifetime
- 1991-10-23 DK DK91918619.7T patent/DK0555276T3/da active
- 1991-10-23 DE DE69112634T patent/DE69112634T2/de not_active Expired - Lifetime
- 1991-10-23 EP EP91918619A patent/EP0555276B1/en not_active Expired - Lifetime
- 1991-10-23 US US08/039,294 patent/US5620690A/en not_active Expired - Lifetime
- 1991-10-23 ES ES91918619T patent/ES2075964T3/es not_active Expired - Lifetime
- 1991-10-23 WO PCT/NL1991/000211 patent/WO1992006710A1/en active IP Right Grant
1995
- 1995-10-18 GR GR950402880T patent/GR3017778T3/el unknown

Also Published As

Publication number	Publication date
ATE127024T1 (de)	1995-09-15
EP0555276A1 (en)	1993-08-18
WO1992006710A1 (en)	1992-04-30
US5620690A (en)	1997-04-15
ES2075964T3 (es)	1995-10-16
GR3017778T3 (en)	1996-01-31
DE69112634T2 (de)	1996-02-08
EP0555276B1 (en)	1995-08-30
DK0555276T3 (da)	1995-09-18
CA2094600C (en)	1998-12-08
CA2094600A1 (en)	1992-04-24
DE69112634D1 (de)	1995-10-05

Publication	Publication Date	Title
NL9002314A (nl)	1992-05-18	Immunogene complexen, in het bijzonder iscoms.
CA1338888C (en)	1997-02-04	Matrix with immunomodulating activity
FI80600B (fi)	1990-03-30	Foerfarande foer framstaellning av immunogent protein- eller peptidkomplex.
EP0231039B1 (en)	1992-01-08	Process for preparing immunological complexes and pharmaceutical composition containing these complexes
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JP4138884B2 (ja)	2008-08-27	新規なサポニン組成物及びその使用
Mizushiri et al.	1990	Chemical characterization of lipopolysaccharides from Proteus strains used in Weil-Felix test
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Bergers et al.	1992	Reconstituted membranes of tumour cells (proteoliposomes) induce specific protection to murine lymphoma cells
Jennemann et al.	1996	Effects of monophosphoryllipid-A on the immunization of mice with keyhole limpet hemocyanin-and muramyldipeptide-ganglioside Gfpt1 conjugates
FI86597B (fi)	1992-06-15	Foerfarande foer framstaellning av immunkomplex.
Tebogo	2004	Separation and characterization of saponins from the bark extract of the South American soap bark tree; Quillaja saponaria Molina:(potential immuno-adjuvant active compounds)

Legal Events

Date	Code	Title	Description
1992-05-18	A1B	A search report has been drawn up
1996-06-03	BV	The patent application has lapsed