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NL8600976A - (-)-1 beta-ethyl-1 alfa-hydroxymethyl-1,2,3,4,6,7,12,12 b alfa-octahydroindool2,3-achinolizine, werkwijze voor de bereiding ervan en farmaceutische preparaten met een dergelijke verbinding erin. - Google Patents

(-)-1 beta-ethyl-1 alfa-hydroxymethyl-1,2,3,4,6,7,12,12 b alfa-octahydroindool2,3-achinolizine, werkwijze voor de bereiding ervan en farmaceutische preparaten met een dergelijke verbinding erin. Download PDF

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Publication number
NL8600976A
NL8600976A NL8600976A NL8600976A NL8600976A NL 8600976 A NL8600976 A NL 8600976A NL 8600976 A NL8600976 A NL 8600976A NL 8600976 A NL8600976 A NL 8600976A NL 8600976 A NL8600976 A NL 8600976A
Authority
NL
Netherlands
Prior art keywords
formula
ethyl
compound
unit dose
quinolizine
Prior art date
Application number
NL8600976A
Other languages
English (en)
Dutch (nl)
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of NL8600976A publication Critical patent/NL8600976A/nl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
NL8600976A 1985-04-19 1986-04-17 (-)-1 beta-ethyl-1 alfa-hydroxymethyl-1,2,3,4,6,7,12,12 b alfa-octahydroindool2,3-achinolizine, werkwijze voor de bereiding ervan en farmaceutische preparaten met een dergelijke verbinding erin. NL8600976A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU851519A HU194221B (en) 1985-04-19 1985-04-19 Process for preparing novel octahydro-indolo/2,3-a/quinoline derivative and pharmaceutical comprising this compound
HU151985 1985-04-19

Publications (1)

Publication Number Publication Date
NL8600976A true NL8600976A (nl) 1986-11-17

Family

ID=10954847

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8600976A NL8600976A (nl) 1985-04-19 1986-04-17 (-)-1 beta-ethyl-1 alfa-hydroxymethyl-1,2,3,4,6,7,12,12 b alfa-octahydroindool2,3-achinolizine, werkwijze voor de bereiding ervan en farmaceutische preparaten met een dergelijke verbinding erin.

Country Status (35)

Country Link
US (1) US4806545A (de)
JP (1) JPH072637B2 (de)
CN (1) CN1023560C (de)
AR (1) AR240699A1 (de)
AT (1) AT390954B (de)
AU (1) AU591896B2 (de)
BE (1) BE904588A (de)
BG (1) BG60433B2 (de)
CA (1) CA1299574C (de)
CH (1) CH668262A5 (de)
CS (1) CS274276B2 (de)
DD (1) DD244556A5 (de)
DE (1) DE3613180C2 (de)
DK (1) DK159780C (de)
EG (1) EG18059A (de)
ES (1) ES8706152A1 (de)
FI (1) FI83870C (de)
FR (1) FR2580649B1 (de)
GB (1) GB2174701B (de)
GR (1) GR861027B (de)
HU (1) HU194221B (de)
IE (1) IE59199B1 (de)
IL (1) IL78538A (de)
IN (1) IN162810B (de)
IT (1) IT1204306B (de)
LU (1) LU86397A1 (de)
NL (1) NL8600976A (de)
NO (1) NO167143C (de)
NZ (1) NZ215879A (de)
PH (1) PH25316A (de)
PT (1) PT82424B (de)
SE (1) SE460196B (de)
SU (1) SU1438612A3 (de)
YU (1) YU44286B (de)
ZA (1) ZA862941B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU191454B (en) * 1984-10-05 1987-02-27 Richter Gedeon Vegyeszeti Gyar Rt.,Hu Process for producing amides of oktahydro-indolo/2,3-a/quinolyzin-1-yl-alkanecarboxylic acids and pharmaceutically acceptable acid additional salts thereof
HU195214B (en) * 1985-04-19 1988-04-28 Richter Gedeon Vegyeszet Process for producing 12b-substituted-1-(hydroxymethyl)-octahydro-indolo /2,3-a/ quinolizine derivatives and pharmaceutical preparations comprising these compounds
HU194220B (en) * 1985-04-19 1988-01-28 Richter Gedeon Vegyeszet Process for production of derivatives of 1,12 b disubstituated-octahydro-indolo /2,3-a/ quinolisine and medical compounds containing thereof
HU207070B (en) * 1990-10-31 1993-03-01 Richter Gedeon Vegyeszet Process for producing 1beta-ethyl-1alpha-hydroxymethyl-1,2,3,4,6,712,12balpha-octahydroindolo(2,3-a) quinolizine
DE19821039A1 (de) * 1998-05-11 1999-11-18 Bayer Ag Verfahren zur Herstellung von (S,S)-Benzyl-2,8-diazabicyclo[4.3.0]nonan
EP1490361B1 (de) * 2002-04-03 2007-10-03 Orion Corporation Polycyclische verbindungen als potenten alpha2-adrenoceptor antagonisten
AU2003235931A1 (en) * 2002-05-13 2003-11-11 Takata Seiyaku Co., Ltd. Vintoperol-containing medicinal composition for transdermal administration

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1499546A (en) * 1974-05-07 1978-02-01 Richter Gedeon Vegyeszet Indolo-quinolizidine derivatives and a process for the preparation thereof
HU170495B (de) * 1974-05-07 1977-06-28
HU195214B (en) * 1985-04-19 1988-04-28 Richter Gedeon Vegyeszet Process for producing 12b-substituted-1-(hydroxymethyl)-octahydro-indolo /2,3-a/ quinolizine derivatives and pharmaceutical preparations comprising these compounds
HU194220B (en) * 1985-04-19 1988-01-28 Richter Gedeon Vegyeszet Process for production of derivatives of 1,12 b disubstituated-octahydro-indolo /2,3-a/ quinolisine and medical compounds containing thereof

Also Published As

Publication number Publication date
CA1299574C (en) 1992-04-28
DE3613180C2 (de) 1995-10-19
ES554143A0 (es) 1987-06-01
EG18059A (en) 1991-06-30
AU591896B2 (en) 1989-12-21
DK179786A (da) 1986-10-20
NO167143B (no) 1991-07-01
GB2174701B (en) 1989-02-15
FI83870C (fi) 1991-09-10
JPS61249986A (ja) 1986-11-07
LU86397A1 (de) 1986-09-02
YU44286B (en) 1990-04-30
PT82424B (pt) 1988-03-03
ES8706152A1 (es) 1987-06-01
IT1204306B (it) 1989-03-01
US4806545A (en) 1989-02-21
GB2174701A (en) 1986-11-12
HUT40433A (en) 1986-12-28
IL78538A0 (en) 1986-08-31
NO167143C (no) 1991-10-09
AT390954B (de) 1990-07-25
BG60433B2 (bg) 1995-03-31
SE8601799D0 (sv) 1986-04-18
FI861641A (fi) 1986-10-20
DK159780B (da) 1990-12-03
SU1438612A3 (ru) 1988-11-15
FI83870B (fi) 1991-05-31
AU5638386A (en) 1986-10-23
YU62486A (en) 1988-06-30
GR861027B (en) 1986-08-12
HU194221B (en) 1988-01-28
IE861033L (en) 1986-10-19
FI861641A0 (fi) 1986-04-18
NO861539L (no) 1986-10-20
GB8609533D0 (en) 1986-05-21
FR2580649B1 (fr) 1991-03-29
PH25316A (en) 1991-04-30
CN1023560C (zh) 1994-01-19
JPH072637B2 (ja) 1995-01-18
PT82424A (en) 1986-05-01
CN86102479A (zh) 1986-10-22
CS286386A2 (en) 1990-09-12
CH668262A5 (de) 1988-12-15
IE59199B1 (en) 1994-01-26
FR2580649A1 (fr) 1986-10-24
BE904588A (fr) 1986-10-14
CS274276B2 (en) 1991-04-11
IL78538A (en) 1989-10-31
IN162810B (de) 1988-07-09
DK179786D0 (da) 1986-04-18
SE460196B (sv) 1989-09-18
NZ215879A (en) 1989-04-26
AR240699A1 (es) 1990-09-28
DE3613180A1 (de) 1986-10-23
IT8620136A0 (it) 1986-04-18
SE8601799L (sv) 1986-10-20
ZA862941B (en) 1986-12-30
ATA102986A (de) 1990-01-15
DD244556A5 (de) 1987-04-08
DK159780C (da) 1991-04-22

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