[go: up one dir, main page]

DK179786D0 - (-)-1beta-ethyl-1alfa-hydroxylmethyl-1,2,3,4,6,7,12,12balfa-octa-hydroindolo(2,3-a)quinolizin og syreadditionssalte deraf, deres fremstilling og anvendelse som farmaceutika - Google Patents

(-)-1beta-ethyl-1alfa-hydroxylmethyl-1,2,3,4,6,7,12,12balfa-octa-hydroindolo(2,3-a)quinolizin og syreadditionssalte deraf, deres fremstilling og anvendelse som farmaceutika

Info

Publication number
DK179786D0
DK179786D0 DK179786A DK179786A DK179786D0 DK 179786 D0 DK179786 D0 DK 179786D0 DK 179786 A DK179786 A DK 179786A DK 179786 A DK179786 A DK 179786A DK 179786 D0 DK179786 D0 DK 179786D0
Authority
DK
Denmark
Prior art keywords
12balfa
hydroindolo
1alfa
quinolizin
hydroxylmethyl
Prior art date
Application number
DK179786A
Other languages
English (en)
Other versions
DK159780C (da
DK159780B (da
DK179786A (da
Inventor
Csaba Szantay
Lajos Szabo
Gyoergy Kalaus
Zsolt Szombathelyi
Egon Karpati
Bela Kiss
Csomor Katalin
Istvan Laszlovszky
Erzsebet Lapis
Laszlo Szporny
Lilla Forgacs
Csaba Kuthi
Aniko Gere
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of DK179786D0 publication Critical patent/DK179786D0/da
Publication of DK179786A publication Critical patent/DK179786A/da
Publication of DK159780B publication Critical patent/DK159780B/da
Application granted granted Critical
Publication of DK159780C publication Critical patent/DK159780C/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Quinoline Compounds (AREA)
DK179786A 1985-04-19 1986-04-18 (-)-1beta-ethyl-1alfa-hydroxylmethyl-1,2,3,4,6,7,12,12balfa-octahydroindolo(2,3-a)quinolizin og syreadditionssalte deraf, dens fremstilling og farmaceutisk praeparat indeholdende den DK159780C (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU151985 1985-04-19
HU851519A HU194221B (en) 1985-04-19 1985-04-19 Process for preparing novel octahydro-indolo/2,3-a/quinoline derivative and pharmaceutical comprising this compound

Publications (4)

Publication Number Publication Date
DK179786D0 true DK179786D0 (da) 1986-04-18
DK179786A DK179786A (da) 1986-10-20
DK159780B DK159780B (da) 1990-12-03
DK159780C DK159780C (da) 1991-04-22

Family

ID=10954847

Family Applications (1)

Application Number Title Priority Date Filing Date
DK179786A DK159780C (da) 1985-04-19 1986-04-18 (-)-1beta-ethyl-1alfa-hydroxylmethyl-1,2,3,4,6,7,12,12balfa-octahydroindolo(2,3-a)quinolizin og syreadditionssalte deraf, dens fremstilling og farmaceutisk praeparat indeholdende den

Country Status (35)

Country Link
US (1) US4806545A (da)
JP (1) JPH072637B2 (da)
CN (1) CN1023560C (da)
AR (1) AR240699A1 (da)
AT (1) AT390954B (da)
AU (1) AU591896B2 (da)
BE (1) BE904588A (da)
BG (1) BG60433B2 (da)
CA (1) CA1299574C (da)
CH (1) CH668262A5 (da)
CS (1) CS274276B2 (da)
DD (1) DD244556A5 (da)
DE (1) DE3613180C2 (da)
DK (1) DK159780C (da)
EG (1) EG18059A (da)
ES (1) ES8706152A1 (da)
FI (1) FI83870C (da)
FR (1) FR2580649B1 (da)
GB (1) GB2174701B (da)
GR (1) GR861027B (da)
HU (1) HU194221B (da)
IE (1) IE59199B1 (da)
IL (1) IL78538A (da)
IN (1) IN162810B (da)
IT (1) IT1204306B (da)
LU (1) LU86397A1 (da)
NL (1) NL8600976A (da)
NO (1) NO167143C (da)
NZ (1) NZ215879A (da)
PH (1) PH25316A (da)
PT (1) PT82424B (da)
SE (1) SE460196B (da)
SU (1) SU1438612A3 (da)
YU (1) YU44286B (da)
ZA (1) ZA862941B (da)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU191454B (en) * 1984-10-05 1987-02-27 Richter Gedeon Vegyeszeti Gyar Rt.,Hu Process for producing amides of oktahydro-indolo/2,3-a/quinolyzin-1-yl-alkanecarboxylic acids and pharmaceutically acceptable acid additional salts thereof
HU194220B (en) * 1985-04-19 1988-01-28 Richter Gedeon Vegyeszet Process for production of derivatives of 1,12 b disubstituated-octahydro-indolo /2,3-a/ quinolisine and medical compounds containing thereof
HU195214B (en) * 1985-04-19 1988-04-28 Richter Gedeon Vegyeszet Process for producing 12b-substituted-1-(hydroxymethyl)-octahydro-indolo /2,3-a/ quinolizine derivatives and pharmaceutical preparations comprising these compounds
HU207070B (en) * 1990-10-31 1993-03-01 Richter Gedeon Vegyeszet Process for producing 1beta-ethyl-1alpha-hydroxymethyl-1,2,3,4,6,712,12balpha-octahydroindolo(2,3-a) quinolizine
DE19821039A1 (de) * 1998-05-11 1999-11-18 Bayer Ag Verfahren zur Herstellung von (S,S)-Benzyl-2,8-diazabicyclo[4.3.0]nonan
IL164203A0 (en) * 2002-04-03 2005-12-18 Orion Corp Polycyclic compounds as potent alpah2-adrenoceptorantagonists
JPWO2003094917A1 (ja) * 2002-05-13 2005-09-08 高田製薬株式会社 ビントペロール含有経皮投与用医薬組成物

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU170495B (da) * 1974-05-07 1977-06-28
GB1499546A (en) * 1974-05-07 1978-02-01 Richter Gedeon Vegyeszet Indolo-quinolizidine derivatives and a process for the preparation thereof
HU194220B (en) * 1985-04-19 1988-01-28 Richter Gedeon Vegyeszet Process for production of derivatives of 1,12 b disubstituated-octahydro-indolo /2,3-a/ quinolisine and medical compounds containing thereof
HU195214B (en) * 1985-04-19 1988-04-28 Richter Gedeon Vegyeszet Process for producing 12b-substituted-1-(hydroxymethyl)-octahydro-indolo /2,3-a/ quinolizine derivatives and pharmaceutical preparations comprising these compounds

Also Published As

Publication number Publication date
DK159780C (da) 1991-04-22
PT82424B (pt) 1988-03-03
ATA102986A (de) 1990-01-15
AT390954B (de) 1990-07-25
SE8601799L (sv) 1986-10-20
DK159780B (da) 1990-12-03
GB2174701B (en) 1989-02-15
NZ215879A (en) 1989-04-26
GR861027B (en) 1986-08-12
IE59199B1 (en) 1994-01-26
NO167143C (no) 1991-10-09
FI83870C (fi) 1991-09-10
ES554143A0 (es) 1987-06-01
BE904588A (fr) 1986-10-14
YU44286B (en) 1990-04-30
NO167143B (no) 1991-07-01
FI861641L (fi) 1986-10-20
PH25316A (en) 1991-04-30
SE460196B (sv) 1989-09-18
CS286386A2 (en) 1990-09-12
DE3613180A1 (de) 1986-10-23
SE8601799D0 (sv) 1986-04-18
CN86102479A (zh) 1986-10-22
ES8706152A1 (es) 1987-06-01
AU5638386A (en) 1986-10-23
FR2580649B1 (fr) 1991-03-29
IL78538A (en) 1989-10-31
DK179786A (da) 1986-10-20
EG18059A (en) 1991-06-30
YU62486A (en) 1988-06-30
CN1023560C (zh) 1994-01-19
LU86397A1 (da) 1986-09-02
FI861641A0 (fi) 1986-04-18
GB2174701A (en) 1986-11-12
CH668262A5 (de) 1988-12-15
NL8600976A (nl) 1986-11-17
BG60433B2 (bg) 1995-03-31
US4806545A (en) 1989-02-21
GB8609533D0 (en) 1986-05-21
FR2580649A1 (fr) 1986-10-24
IL78538A0 (en) 1986-08-31
JPS61249986A (ja) 1986-11-07
IT8620136A0 (it) 1986-04-18
IN162810B (da) 1988-07-09
PT82424A (en) 1986-05-01
HU194221B (en) 1988-01-28
DE3613180C2 (de) 1995-10-19
IT1204306B (it) 1989-03-01
ZA862941B (en) 1986-12-30
CA1299574C (en) 1992-04-28
JPH072637B2 (ja) 1995-01-18
FI83870B (fi) 1991-05-31
HUT40433A (en) 1986-12-28
DD244556A5 (de) 1987-04-08
CS274276B2 (en) 1991-04-11
SU1438612A3 (ru) 1988-11-15
NO861539L (no) 1986-10-20
AU591896B2 (en) 1989-12-21
AR240699A1 (es) 1990-09-28
IE861033L (en) 1986-10-19

Similar Documents

Publication Publication Date Title
DK605489A (da) Beta-amino-boronsyre-derivater, deres fremstilling og anvendelse
DK374289A (da) Indazol-3-carboxylsyrederivater, deres fremstilling og anvendelse
DK266486D0 (da) Quinoloncarboxylsyreestere eller farmaceutisk anvendelige hydratereller syreadditionssalte deraf, deres fremstilling og anvendelse
DK146786D0 (da) 4'-demethyl-4-epipodophyllotoxinderivater, deres fremstilling og anvendelse i laegemidler, isaer som antitumormidler
DK131887D0 (da) 1,2,3,4-tetrahydro-3-carbamoyl-2-thioxo/oxo-5-pyrimidencarboxylsyre-derivater og deres anvendelse som laegemidler
NO891749D0 (no) Syreaddisjonssalter, deres fremstilling og anvendelse.
DK112287D0 (da) Anvendelse af 2-alkoxy-n-(1-azabicyclo-oe2,2,2aaoct-3-yl)-benzamider og -thiobenzamider samt farmaceutisk acceptable syreadditionssalte deraf som laegemidler
DK521986A (da) Benzylaminderivater eller syreadditionssalte deraf, deres fremstilling og anvendelse som fungicider
DK179786D0 (da) (-)-1beta-ethyl-1alfa-hydroxylmethyl-1,2,3,4,6,7,12,12balfa-octa-hydroindolo(2,3-a)quinolizin og syreadditionssalte deraf, deres fremstilling og anvendelse som farmaceutika
DK513188D0 (da) Aminosyreestre, deres fremstilling og anvendelse som laegemidler
DK180086D0 (da) 12b-substituerede 1-hydroxymethyl-octahydroindolo(2,3-a)-quinolizinderivater eller isomere eller syreadditionssalte deraf, deres fremstilling og anvendelse som farmaceutika
DK192588D0 (da) Pyrrolaldehyder eller farmaceutisk acceptable syreadditionssalte deraf, deres fremstilling og anvendelse
DK527886D0 (da) 2,3,4,6-tetrasubstituerede 1,4-dihydropyridin-5-carboxylsyrederivater samt deres fremstilling og anvendelse
DK238089A (da) Substituerede 3-aminosydnoniminer eller farmaceutisk acceptable syreadditionssalte deraf, deres fremstilling og anvendelse
DK504386D0 (da) Gonadoliberinanaloge og farmaceutisk acceptable syreadditionssalte, deres fremstilling og anvendelse
DK523289A (da) 2,3,5,6-tetrahydro(1,3,6)triazocino(1,2-a)benzim- idazoler eller farmaceutisk acceptable syreadditionssalte deraf og deres anvendelse
DK37787D0 (da) 2,3-dioxabicyclooe3,3,0aaoctan-derivater og deres anvendelse som laegemidler
DK453485D0 (da) 1,2,3,4,6,7,12,1rb-octahydroindolo-(2,3-a)quinolizin-1-yl-alkancarboxylsyreamider og farmaceutisk anvendelige syreadditionssalte deraf,deres fremstilling og anvendelse
DK325687A (da) Hydrogenerede 1-phenoxyalkylpyridin-3-carboxylsyreforbindelser og salte deraf samt deres fremstilling og anvendelse
DK292086D0 (da) 2-halogennicergolinderivater eller syreadditionssalte deraf, deres fremstilling og anvendelse
DK291986A (da) 10alfa-methoxy-6-methylergolinderivater eller fysiologisk acceptable syreadditionssalte deraf, deres fremstilling og anvendelse
DK447986A (da) 2-aryl-4,5,6,7-tetrahydroisoindolinoner, deres fremstilling og anvendelse som herbicider
DK202986A (da) Permethrinsyre-(triazolyl-alkyl)-estere, deres fremstilling og anvendelse
DK514686D0 (da) 5-naphthyl-2,4-dialkyl-3h-1,2,4-triazol-3-thioner og tautomer deraf, deres fremstilling og anvendelse som antidepressive midler
DK208687A (da) Substituerede quinoxalinyloxy-phenoxypropionsyre-derivater, deres fremstilling og anvendelse som herbicide midler