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MX355915B - Moduladores del receptor de androgenos y usos de los mismos. - Google Patents

Moduladores del receptor de androgenos y usos de los mismos.

Info

Publication number
MX355915B
MX355915B MX2015009660A MX2015009660A MX355915B MX 355915 B MX355915 B MX 355915B MX 2015009660 A MX2015009660 A MX 2015009660A MX 2015009660 A MX2015009660 A MX 2015009660A MX 355915 B MX355915 B MX 355915B
Authority
MX
Mexico
Prior art keywords
receptor modulators
androgen receptor
compounds
androgen
medicaments
Prior art date
Application number
MX2015009660A
Other languages
English (en)
Inventor
D Smith Nicholas
Bonnefous Celine
D Julien Jackaline
Original Assignee
Aragon Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aragon Pharmaceuticals Inc filed Critical Aragon Pharmaceuticals Inc
Publication of MX355915B publication Critical patent/MX355915B/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
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    • A61K31/33—Heterocyclic compounds
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    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • A61K31/4184—1,3-Diazoles condensed with carbocyclic rings, e.g. benzimidazoles
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Abstract

La presente invención se refiere a compuestos que son moduladores del receptor de andrógenos. También se describen composiciones farmacéuticas y medicamentos que incluyen los compuestos descritos aquí, así como también métodos para utilizar dichos moduladores del receptor de andrógenos, solos y en combinación con otros compuestos, para tratar enfermedades o afecciones que son mediadas o dependen de receptores de andrógenos.
MX2015009660A 2010-02-16 2011-02-16 Moduladores del receptor de androgenos y usos de los mismos. MX355915B (es)

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