[go: up one dir, main page]

MX352434B - Formulaciones topicas que tienen biodisponibilidad aumentada. - Google Patents

Formulaciones topicas que tienen biodisponibilidad aumentada.

Info

Publication number
MX352434B
MX352434B MX2013012936A MX2013012936A MX352434B MX 352434 B MX352434 B MX 352434B MX 2013012936 A MX2013012936 A MX 2013012936A MX 2013012936 A MX2013012936 A MX 2013012936A MX 352434 B MX352434 B MX 352434B
Authority
MX
Mexico
Prior art keywords
topical formulations
enhanced bioavailability
lipophilic bioactive
benefit
utilized
Prior art date
Application number
MX2013012936A
Other languages
English (en)
Inventor
Patrick Mccook John
Rajin Narain Niven
Persaud Indushekhar
Original Assignee
Berg Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Berg Llc filed Critical Berg Llc
Publication of MX352434B publication Critical patent/MX352434B/es

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/127—Synthetic bilayered vehicles, e.g. liposomes or liposomes with cholesterol as the only non-phosphatidyl surfactant
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A61K31/122—Ketones having the oxygen directly attached to a ring, e.g. quinones, vitamin K1, anthralin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/02—Inorganic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/12—Carboxylic acids; Salts or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18—Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
    • A61K47/186—Quaternary ammonium compounds, e.g. benzalkonium chloride or cetrimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/24—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing atoms other than carbon, hydrogen, oxygen, halogen, nitrogen or sulfur, e.g. cyclomethicone or phospholipids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/34—Macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyesters, polyamino acids, polysiloxanes, polyphosphazines, copolymers of polyalkylene glycol or poloxamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/14—Liposomes; Vesicles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
    • A61K8/35—Ketones, e.g. benzophenone
    • A61K8/355—Quinones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • Dermatology (AREA)
  • Birds (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Inorganic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Emergency Medicine (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

La presente descripción proporciona composiciones adecuadas para suministrar agentes lipofílicos bioactivos. Las composiciones pueden utilizarse para tratar numerosas enfermedades y padecimientos que pueden beneficiarse de la aplicación de un agente lipofílico bioactivo.
MX2013012936A 2007-03-22 2008-03-21 Formulaciones topicas que tienen biodisponibilidad aumentada. MX352434B (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US91955407P 2007-03-22 2007-03-22
PCT/US2008/057786 WO2008116135A2 (en) 2007-03-22 2008-03-21 Topical formulations having enhanced bioavailability

Publications (1)

Publication Number Publication Date
MX352434B true MX352434B (es) 2017-11-24

Family

ID=39766784

Family Applications (3)

Application Number Title Priority Date Filing Date
MX2009010170A MX337408B (es) 2007-03-22 2008-03-21 Formulaciones topicas que tienen biodisponibilidad aumentada.
MX2015000284A MX363435B (es) 2007-03-22 2008-03-21 Formulaciones topicas que tienen biodisponibilidad aumentada.
MX2013012936A MX352434B (es) 2007-03-22 2008-03-21 Formulaciones topicas que tienen biodisponibilidad aumentada.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
MX2009010170A MX337408B (es) 2007-03-22 2008-03-21 Formulaciones topicas que tienen biodisponibilidad aumentada.
MX2015000284A MX363435B (es) 2007-03-22 2008-03-21 Formulaciones topicas que tienen biodisponibilidad aumentada.

Country Status (10)

Country Link
US (4) US8454945B2 (es)
EP (2) EP3607937A1 (es)
AU (2) AU2008228764B2 (es)
BR (1) BRPI0809164B8 (es)
CA (2) CA2823407C (es)
ES (1) ES2755840T3 (es)
MX (3) MX337408B (es)
NO (1) NO20093032L (es)
WO (1) WO2008116135A2 (es)
ZA (1) ZA201400071B (es)

Families Citing this family (121)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH0752317A (ja) * 1993-08-13 1995-02-28 Asahi Shiyueebell Kk 積層板
US7629384B2 (en) * 1997-09-17 2009-12-08 Strategic Science & Technologies, Llc Topical delivery of L-arginine to cause beneficial effects
US7914814B2 (en) 1997-09-17 2011-03-29 Strategic Science & Technologies, Llc Topical delivery of arginine of cause beneficial effects
CA2556967A1 (en) * 2004-02-23 2005-09-09 Strategic Science & Technologies, Llc Topical delivery of a nitric oxide donor to improve body and skin appearance
US9226909B2 (en) 2004-04-19 2016-01-05 Strategic Science & Technologies, Llc Beneficial effects of increasing local blood flow
US9050365B2 (en) * 2004-04-19 2015-06-09 Strategic Science & Technologies, Llc Transdermal delivery of beneficial substances effected by a hostile biophysical environment
US20110028548A1 (en) * 2004-04-19 2011-02-03 Strategic Science & Technologies, Llc Beneficial effects of increasing local blood flow
EA031017B1 (ru) * 2008-02-04 2018-11-30 Ферринг Б.В. Способ поддержания или замещения фазы жёлтого тела
WO2009101412A1 (en) * 2008-02-13 2009-08-20 Cipla Limited Topical pharmaceutical composition
EA023827B1 (ru) 2008-04-11 2016-07-29 БЕРГ ЭлЭлСи Способ индуцирования апоптоза в клетке
GB2465746B (en) * 2008-11-21 2011-02-16 Fortune Apex Dev Ltd Pharmaceutical composition for topical application
WO2010077723A1 (en) * 2009-01-05 2010-07-08 Hauck John F Method for treating nocturia
US20100247666A1 (en) * 2009-03-24 2010-09-30 Macleod Steven K Method for Preparing Suspensions of Low-Solubility Materials
US9775802B2 (en) 2009-03-24 2017-10-03 Bausch & Lomb Incorporated Method for preparing suspensions of low-solubility materials
EP2424581B1 (en) 2009-04-28 2017-03-01 SurModics, Inc. Devices and methods for delivery of bioactive agents
WO2010132507A2 (en) * 2009-05-11 2010-11-18 Cytotech Labs, Llc Methods for treatment of disease using an epimetabolic shifter (coenzyme q10)
US12138268B2 (en) 2009-06-24 2024-11-12 Strategic Science & Technologies, Llc Treatment of erectile dysfunction and other indications
EP2445493A1 (en) 2009-06-24 2012-05-02 Strategic Science & Technologies, LLC Topical composition containing naproxen
US8604081B2 (en) 2009-06-24 2013-12-10 Strategic Science & Technologies, Llc Topical composition containing ibuprofen
AU2015203547B2 (en) * 2009-06-24 2017-05-18 Strategic Science & Technologies, Llc Topical composition containing ibuprofen
US11684624B2 (en) 2009-06-24 2023-06-27 Strategic Science & Technologies, Llc Treatment of erectile dysfunction and other indications
US20120251525A1 (en) * 2009-06-30 2012-10-04 Streeper Robert T Method of utilizing azelaic acid esters to modulate communications mediated by biological molecules
MX2011008660A (es) * 2009-07-24 2011-09-22 Mika Pharma Ges Fuer Die Entwicklung Und Vermarktung Pharmazeutischer Produkte Mbh Metodo de desarrollo de composicion liquida para aplicacion en la piel como espuma y composicion aplicable topicamente.
WO2011063531A1 (en) * 2009-11-27 2011-06-03 Nuvo Research Inc. Topical ibuprofen formulations
US20110150798A1 (en) * 2009-12-21 2011-06-23 Sarah Bacus Compositions and methods for increasing cellular far and bleaching skin
US20110150856A1 (en) 2009-12-21 2011-06-23 Sarah Bacus Compositions and methods for treatment of vitiligo
SG10201501872XA (en) * 2010-03-12 2015-05-28 Berg Llc Intravenous formulations of coenzyme q10 (coq10) and methods of use thereof
WO2011162818A2 (en) * 2010-06-23 2011-12-29 Controlled Nanovolumes, Inc. Lecithin carrier vesicles and methods of making the same
US20130202677A1 (en) * 2010-09-30 2013-08-08 Sekisui Medical Co. Ltd Patch
WO2012092527A1 (en) * 2010-12-29 2012-07-05 Strategic Science & Technologies, Llc Delivery of treatments transdermally for fungal infections and other indications
HUE050862T2 (hu) * 2010-12-29 2021-01-28 Strategic Science & Tech Llc Merevedési zavar és más indikációk kezelése
EP2658554A4 (en) * 2010-12-29 2015-01-07 Strategic Science & Tech Llc SYSTEMS AND METHOD FOR THE TREATMENT OF ALLERGIES AND OTHER INDICATIONS
CN103442722A (zh) * 2010-12-29 2013-12-11 战略科学与技术有限责任公司 Cox-2抑制剂和相关的化合物、及其递送系统和方法
EP2667853A4 (en) * 2011-01-25 2014-08-20 Procter & Gamble LIPOSOME AND BODY CARE COMPOSITION THEREWITH
US20160235669A1 (en) * 2011-03-21 2016-08-18 Food Industry Research And Development Institute Process for preparing water dispersions containing high concentration of nano/submicron, hydrophobic, functional compounds and water dispersions obtainable therefrom
JP6092844B2 (ja) 2011-04-04 2017-03-08 バーグ エルエルシー 中枢神経系腫瘍の治療方法
US9861727B2 (en) 2011-05-20 2018-01-09 Surmodics, Inc. Delivery of hydrophobic active agent particles
US9757497B2 (en) 2011-05-20 2017-09-12 Surmodics, Inc. Delivery of coated hydrophobic active agent particles
US10213529B2 (en) 2011-05-20 2019-02-26 Surmodics, Inc. Delivery of coated hydrophobic active agent particles
CN107095863A (zh) 2011-06-17 2017-08-29 博格有限责任公司 可吸入药物组合物
KR101808078B1 (ko) * 2011-08-10 2017-12-13 주식회사 아이피어리스 리조레시친 및 글리세로포스포콜린을 이용한 리포좀 제제, 및 이를 포함하는 퍼스널 케어 조성물
JP2013060393A (ja) * 2011-09-13 2013-04-04 Nitto Denko Corp 経皮吸収促進用組成物および貼付製剤
JP5820207B2 (ja) 2011-09-13 2015-11-24 日東電工株式会社 経皮吸収促進用組成物および貼付製剤
JP5820206B2 (ja) 2011-09-13 2015-11-24 日東電工株式会社 経皮吸収促進用組成物および貼付製剤
CN102366409B (zh) * 2011-09-14 2013-03-20 海南灵康制药有限公司 一种尼扎替丁脂质体固体制剂
PL2782584T3 (pl) 2011-11-23 2021-12-13 Therapeuticsmd, Inc. Naturalne skojarzone hormonalne formulacje i terapie zastępcze
US9301920B2 (en) 2012-06-18 2016-04-05 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US9468599B2 (en) 2011-12-27 2016-10-18 Cmpd Licensing, Llc Composition and method for compounded therapy
US9962391B2 (en) 2011-12-27 2018-05-08 Cmpd Licensing, Llc Composition and method for compounded therapy
US11213501B2 (en) 2011-12-27 2022-01-04 Cmpd Licensing, Llc Composition and method for compounded therapy
US10813897B2 (en) 2011-12-27 2020-10-27 Cmpd Licensing, Llc Composition and method for compounded therapy
US11213500B2 (en) 2011-12-27 2022-01-04 Cmpd Licensing, Llc Composition and method for compounded therapy
CA2875150C (en) 2012-06-01 2020-10-27 Berg Llc Treatment of solid tumors using coenzyme q10
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20130338122A1 (en) 2012-06-18 2013-12-19 Therapeuticsmd, Inc. Transdermal hormone replacement therapies
CN102727438B (zh) * 2012-06-29 2014-07-02 海南美兰史克制药有限公司 瑞格列奈脂质体固体制剂
EP3326613A1 (en) 2012-07-26 2018-05-30 Camurus AB Opioid formulations
SG11201500554XA (en) 2012-07-26 2015-02-27 Camurus Ab Opioid formulations
US11246963B2 (en) 2012-11-05 2022-02-15 Surmodics, Inc. Compositions and methods for delivery of hydrophobic active agents
JP6438406B2 (ja) * 2012-11-05 2018-12-12 サーモディクス，インコーポレイテッド 疎水性生理活性物質を送達するための組成物および方法
US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10537581B2 (en) 2012-12-21 2020-01-21 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
EP2948134B1 (en) 2013-01-24 2020-03-04 Palvella Therapeutics, Inc. Compositions for transdermal delivery of mtor inhibitors
CA2902787A1 (en) * 2013-02-28 2014-09-04 Precision Dermatology, Inc. Topical formulations of corticosteroids with enhanced bioavailability
WO2014134427A1 (en) * 2013-02-28 2014-09-04 Precision Dermatology, Inc. Controlling the bioavailability of active ingredients in topical formulations
US9511144B2 (en) 2013-03-14 2016-12-06 The Proctor & Gamble Company Cosmetic compositions and methods providing enhanced penetration of skin care actives
US20140276360A1 (en) * 2013-03-15 2014-09-18 Abbott Cardiovascular Systems Inc. Electrophorectic drug coated balloon and conductive polymer coating
SG10201903112WA (en) 2013-04-08 2019-05-30 Berg Llc Treatment of cancer using coenzyme q10 combination therapies
WO2015035094A1 (en) 2013-09-04 2015-03-12 Berg Llc Methods of treatment of cancer by continuous infusion of coenzyme q10
CN103432073A (zh) * 2013-09-11 2013-12-11 中国药科大学 一种肿瘤靶向纳米制剂及其制备方法
WO2015042589A1 (en) * 2013-09-23 2015-03-26 Verso PV, LLC Personal vaporizer liquid for emulsifying oil-soluble compounds and resins
US20150174254A1 (en) * 2013-12-23 2015-06-25 Mcneil-Ppc, Inc. Topical gel compositions including polycaprolactone polymer and methods for enhancing the topical application of a benefit agent
US20150283163A1 (en) * 2014-04-04 2015-10-08 Organic Medical Ventures, L.L.C. Muscle treatment composition and method making same
KR20170005819A (ko) 2014-05-22 2017-01-16 쎄러퓨틱스엠디, 인코퍼레이티드 천연 복합 호르몬 대체 제형 및 요법
BR112016029338A2 (pt) 2014-07-29 2017-08-22 Therapeuticsmd Inc creme transdérmico
US11007161B1 (en) 2014-12-31 2021-05-18 Eric Morrison Ibuprofen nanoparticle carriers encapsulated with hermatic surfactant films
US10596117B1 (en) 2014-12-31 2020-03-24 Eric Morrison Lipoleosomes as carriers for aromatic amide anesthetic compounds
US10561627B2 (en) 2014-12-31 2020-02-18 Eric Morrison Ibuprofen nanoparticle carriers encapsulated with hermetic surfactant films
CN114588154A (zh) * 2015-02-05 2022-06-07 纪念斯隆凯特林癌症中心 用于治疗水肿的组合物和方法
US20160346219A1 (en) 2015-06-01 2016-12-01 Autotelic Llc Phospholipid-coated therapeutic agent nanoparticles and related methods
US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
US9585867B2 (en) 2015-08-06 2017-03-07 Charles Everett Ankner Cannabinod formulation for the sedation of a human or animal
US9610242B2 (en) 2015-08-18 2017-04-04 Concept Labs, Inc. Water-gel emulsion compositions and methods
US20170106020A1 (en) * 2015-10-19 2017-04-20 Stanley James Harless Anesthetic/analgesic composition
WO2017173044A1 (en) 2016-04-01 2017-10-05 Therapeuticsmd Inc. Steroid hormone compositions in medium chain oils
RU2018133932A (ru) 2016-04-01 2020-05-12 Терапьютиксмд, Инк. Фармацевтическая композиция стероидного гормона
AU2017285725B2 (en) * 2016-06-13 2021-08-19 Uti Limited Partnership Methods and compositions for modulating opioid withdrawal symptoms
CN108066767A (zh) * 2016-11-17 2018-05-25 北京科百大科技有限责任公司 一种稳定的含伊维菌素类药物的自乳化固体组合物
US10898446B2 (en) 2016-12-20 2021-01-26 Surmodics, Inc. Delivery of hydrophobic active agents from hydrophilic polyether block amide copolymer surfaces
AU2018205253B2 (en) 2017-01-06 2022-01-13 Palvella Therapeutics, Inc. Anhydrous compositions of mTOR inhibitors and methods of use
CA3051787A1 (en) * 2017-03-24 2018-09-27 Teo ALBARANO Pharmaceutical compositions
BR112019024116A2 (pt) 2017-05-17 2020-06-02 Berg Llc Use da coenzima q10 formulações no tratamento e prevenção de epidermólise bolhosa
KR20200051689A (ko) * 2017-09-11 2020-05-13 아토사 테라퓨틱스, 인크. 국소 조성물 및 치료 방법
KR20240155974A (ko) 2017-09-11 2024-10-29 아토사 테라퓨틱스, 인크. 엔독시펜을 제조 및 사용하는 방법
EP3681479B1 (en) 2017-09-15 2024-01-31 Dyve Biosciences, Inc. Sodium bicarbonate for use in the treatment of gout and related disorders
CN107522735A (zh) * 2017-09-21 2017-12-29 安徽元创科技有限公司 以溶剂法生产低粘度磷脂产品的方法
JP2021530463A (ja) 2018-07-02 2021-11-11 パルヴェラ セラピューティクス、インク． ｍＴＯＲ阻害剤の無水組成物および使用方法
NZ781120A (en) 2019-04-12 2024-09-27 Ecolab Usa Inc Antimicrobial multi-purpose cleaner and methods of making and using the same
US12201591B2 (en) 2019-07-03 2025-01-21 Atossa Therapeutics, Inc. Sustained release compositions of endoxifen
EP3886799B1 (en) 2019-08-07 2023-11-15 Aneira Pharma, Inc. Compositions for the treatment of hair loss
US12226552B2 (en) 2019-09-30 2025-02-18 Surmodics, Inc. Active agent depots formed in situ
US20210322339A1 (en) 2019-11-20 2021-10-21 Berg Llc Combination therapy of coenzyme q10 and radiation for treatment of glioma
CN111166735B (zh) * 2020-01-15 2023-08-18 延边大学 邻苯二甲酸-双-(2-乙基庚基)酯在抑制脂肪蓄积中的应用
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations
CN111407893A (zh) * 2020-04-26 2020-07-14 深圳大学 p38-MAPK信号通路的抑制剂在制备用于治疗鼻咽癌的药物中的应用
EP4142692A4 (en) * 2020-04-30 2024-05-22 Blue Sky Innovation, LLC SUPEROXIDE DISMUTASE COMPOSITIONS AND METHODS
EP4178356A1 (en) * 2020-07-09 2023-05-17 Symrise AG Compositions with virucidal and/or antiviral activity
US11179353B1 (en) * 2020-09-22 2021-11-23 Rythera Therapeutics, Inc. Composition and method for prevention and treatment of radiation dermatitis
WO2022155341A1 (en) * 2021-01-13 2022-07-21 Dyve Biosciences, Inc. Transdermal formulations for phosphodiesterase-5 inhibitors
US20220354879A1 (en) * 2021-05-04 2022-11-10 Sovida Solutions Ltd. Nicotinamide adenine dinucleotide (nad) compositions, methods of manufacturing thereof, and methods of use thereof
KR102730602B1 (ko) * 2021-06-24 2024-11-18 주식회사 종근당 칸데사르탄, 암로디핀 및 아토르바스타틴을 포함하는 약제학적 복합제제
BE1030538B1 (nl) * 2022-05-18 2023-12-19 Bogaert Gina Van Liposomaal preparaat met ingekapselde hormonen, werkwijze voor de productie en gebruik ervan
CN114939115B (zh) * 2022-06-09 2023-07-25 上海智同医药科技有限公司 一种药物组合物及由其制成的微丸和胶囊
CN115069241A (zh) * 2022-06-10 2022-09-20 同济大学 膦辅助补丁调制负载性金纳米簇及制备方法和催化应用
WO2024174011A1 (pt) * 2023-02-24 2024-08-29 Rossi Bergmann Bartira Lipossoma, método de preparo de um lipossoma, composição intranasal compreendendo lipossoma, método de preparo de composição intranasal, kit e uso da composição

Family Cites Families (207)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4525350A (en) 1975-02-20 1985-06-25 The New England Institute, Inc. Methods of stimulating host defense system with coenzymes Q4 to Q.sub.1
IT1157269B (it) 1982-03-19 1987-02-11 Seuref Ag Nuove formulazioni farmaceutiche contenenti il coenzima q10 adatte per la somministrazione topica
JPS58201711A (ja) 1982-05-19 1983-11-24 Eisai Co Ltd ユビデカレノン含有リポソ−ム被覆体
US4515736A (en) 1983-05-12 1985-05-07 The Regents Of The University Of California Method for encapsulating materials into liposomes
US4895727A (en) 1985-05-03 1990-01-23 Chemex Pharmaceuticals, Inc. Pharmaceutical vehicles for exhancing penetration and retention in the skin
US5651991A (en) 1987-10-28 1997-07-29 Nippon Shinyaku Co. Ltd. Drug carriers
GB8811410D0 (en) * 1988-05-13 1988-06-15 Unilever Plc Treatment of skin disorders
US5015483A (en) 1989-02-09 1991-05-14 Nabisco Brands, Inc. Liposome composition for the stabilization of oxidizable substances
US5585112A (en) 1989-12-22 1996-12-17 Imarx Pharmaceutical Corp. Method of preparing gas and gaseous precursor-filled microspheres
US5580575A (en) 1989-12-22 1996-12-03 Imarx Pharmaceutical Corp. Therapeutic drug delivery systems
US5962243A (en) 1990-04-18 1999-10-05 Board Of Regents, The University Of Texas System Methods for the identification of farnesyltransferase inhibitors
CA2073353C (fr) 1990-11-14 2003-10-28 Alexandre Zysman Composes amphiphiles non-ioniques derives du glycerol, leur procede de preparation, composes intermediaires correspondants et compositions contenant lesdits composes
SE502569C2 (sv) 1991-05-31 1995-11-13 British Tech Group Användning av en immunologiskt inert matris av en sterol och saponiner som kan bilda sfäriska nanopartiklar med snäv storleksfördelning som läkemedelsbärare, partiklar, komposition samt kit
US5378461A (en) 1991-07-12 1995-01-03 Neigut; Stanley J. Composition for the topical treatment of skin damage
US6461593B1 (en) 1992-02-19 2002-10-08 Biomedical And Clinical Research Therapy with coenzyme Q10 to reduce subgingival microorganisms in patients with periodontal disease
AU676470B2 (en) 1992-02-24 1997-03-13 East Carolina University Method of inhibiting carcinogenesis by treatment with dehydroepiandrosterone and analogs thereof
US5602184A (en) 1993-03-03 1997-02-11 The United States Of America As Represented By Department Of Health And Human Services Monoterpenes, sesquiterpenes and diterpenes as cancer therapy
EP0616801B1 (de) 1993-03-24 1998-05-27 Novartis AG Verfahren zur Herstellung einer Liposomendispersion im Hochdruckbereich
US7083572B2 (en) 1993-11-30 2006-08-01 Bristol-Myers Squibb Medical Imaging, Inc. Therapeutic delivery systems
DE4410238A1 (de) 1994-03-25 1995-09-28 Beiersdorf Ag Hautpflegemittel
US20020049422A1 (en) 1994-03-31 2002-04-25 Brewitt Barbara A. Homeopathic preparations
CA2207093A1 (en) 1994-12-06 1996-06-13 Ryan Pharmaceuticals, Inc. Water soluble ubiquinone compositions, prodrugs, and methods relating thereto
US6005086A (en) 1995-01-13 1999-12-21 The Salk Institute For Biological Studies Farnesoid activated receptor polypeptides, and nucleic acid encoding the same
DE19537027A1 (de) 1995-10-05 1997-04-10 Beiersdorf Ag Hautpflegemittel für alte Haut
US5944012A (en) 1996-03-25 1999-08-31 Pera; Ivo E. Method for dispensing antioxidant vitamins by inhalation background of the invention
DE19615577A1 (de) 1996-04-19 1997-10-23 Beiersdorf Ag Verwendung von Salicin als antiirritativer Wirkstoff in kosmetischen und topischen dermatologischen Zubereitungen
US5891465A (en) 1996-05-14 1999-04-06 Biozone Laboratories, Inc. Delivery of biologically active material in a liposomal formulation for administration into the mouth
GB9625895D0 (en) 1996-12-13 1997-01-29 Riley Patrick A Novel compound useful as therapeutic agents and assay reagents
US20040228910A1 (en) 1997-02-11 2004-11-18 Mse Pharmazeutika Gmbh Transdermal, oral and intravenous formulations of 2, 3-dimethoxy-5-methyl-6-decaprenyl-1, 4-benzoquinone
DE59800863D1 (de) 1997-02-11 2001-07-19 Mse Pharmazeutika Gmbh Transdermale, orale und intravenöse zubereitungen von 2,3-dimethoxy-5-methyl-6-decaprenyl-1,4-benzochinon
EP1007018B1 (de) 1997-02-12 2003-10-08 MSE Pharmazeutika GmbH Verwendung von 2,3-dimethoxy-5-methyl-6-decaprenyl-1,4-benzochinon inder behandlung von tinnitus
US6599513B2 (en) 1997-05-27 2003-07-29 Sembiosys Genetics Inc. Products for topical applications comprising oil bodies
US6372234B1 (en) 1997-05-27 2002-04-16 Sembiosys Genetics Inc. Products for topical applications comprising oil bodies
US6726924B2 (en) 1997-09-04 2004-04-27 Biozone Laboratories, Inc. Oral liposomal delivery system
US6696484B2 (en) 1997-10-31 2004-02-24 University Of Chicago Office Of Technology And Intellectual Property Method and compositions for regulation of 5-alpha reductase activity
WO1999022728A1 (en) 1997-10-31 1999-05-14 Arch Development Corporation Methods and compositions for regulation of 5-alpha reductase activity
WO1999026657A1 (en) 1997-11-25 1999-06-03 Musc Foundation For Research Development Inhibitors of nitric oxide synthase
US6372880B1 (en) 1997-12-25 2002-04-16 Mitsui Chemicals, Inc. Copolymer and process for preparing the same
KR100657388B1 (ko) 1998-04-14 2006-12-13 교와 학꼬 고교 가부시키가이샤 미생물에 의한 이소프레노이드 화합물의 제조 방법
US6503523B2 (en) 1998-05-07 2003-01-07 Gs Development A.B. Skin care agents containing combinations of active agents consisting of vitamin a derivatives and UBI- or plastoquinones
DE19828081C2 (de) 1998-06-24 2000-08-10 Cognis Deutschland Gmbh W/O-Emulsionsgrundlagen
EP1097270B1 (de) 1998-07-16 2003-06-04 Cognis Deutschland GmbH & Co. KG Verwendung von pit-emulsionen
US6048886A (en) 1998-10-05 2000-04-11 Neigut; Stanley Compositions and delivery systems for the topical treatment of psoriasis and other conditions of the skin
US20040034107A1 (en) 1999-02-11 2004-02-19 Mse Pharmazeutika Gmbh Ubiquinone Qn for the treatment of pain
US20030104048A1 (en) 1999-02-26 2003-06-05 Lipocine, Inc. Pharmaceutical dosage forms for highly hydrophilic materials
US7374779B2 (en) 1999-02-26 2008-05-20 Lipocine, Inc. Pharmaceutical formulations and systems for improved absorption and multistage release of active agents
US6482943B1 (en) 1999-04-30 2002-11-19 Slil Biomedical Corporation Quinones as disease therapies
US6803193B1 (en) 1999-06-23 2004-10-12 The Penn State Research Foundation Methods to identify modulators of the mevalonate pathway in sterol synthesis
DE59912559D1 (de) 1999-07-02 2005-10-20 Cognis Ip Man Gmbh Mikrokapseln - III
US6630160B1 (en) 1999-09-07 2003-10-07 Genetic Services Management, Inc. Process to modulate disease risk with doses of a nutraceutical
US20030104080A1 (en) 1999-09-07 2003-06-05 Singh Parashu Ram Topical urea composition
US20060204458A1 (en) * 2000-10-26 2006-09-14 Holloway William D Jr Anti-aging methods and composition
US20030180352A1 (en) 1999-11-23 2003-09-25 Patel Mahesh V. Solid carriers for improved delivery of active ingredients in pharmaceutical compositions
US7083780B2 (en) 1999-12-11 2006-08-01 Cognis Deutschland Gmbh & Co. Kg Cosmetic composition containing hydroxyethers
EP1239826A2 (de) 1999-12-20 2002-09-18 Cognis France S.A. Kosmetische und/oder pharmazeutische zubereitungen
US20020044913A1 (en) 2000-02-11 2002-04-18 Hamilton Nathan D. Cosmetics to support skin metabolism
FR2804864B1 (fr) 2000-02-11 2003-04-04 Serobiologiques Lab Sa Extraits de residus issus de la fabrication du vin et leur utilisation en cosmetique ou pharmacologie
DE10007322A1 (de) 2000-02-17 2001-08-23 Cognis Deutschland Gmbh Perlglanzmittel
ATE479419T1 (de) 2000-02-17 2010-09-15 Basf Se Wässrige dispersion wasserunlöslicher organischer uv-filtersubstanzen
FR2805464B1 (fr) 2000-02-25 2003-02-14 Serobiologiques Lab Sa Preparations cosmetiques contenant des extraits de la plante mourera fluviatilis
DE10009996B4 (de) 2000-03-02 2005-10-13 Cognis Ip Management Gmbh Feststoffgranulate mit monodisperser Korngrößenverteilung, ein Verfahren zu ihrer Herstellung sowie ihre Verwendung
WO2001072262A2 (en) 2000-03-27 2001-10-04 Schott Glas New cosmetic, personal care, cleaning agent, and nutritional supplement compositions comprising bioactive glass and methods of making and using the same
US6447760B2 (en) * 2000-05-08 2002-09-10 Playtex Products, Inc. Sunless tanning compositions
US6468552B1 (en) 2000-06-02 2002-10-22 Neutrogena Corporation Stabilized compositions containing oxygen-labile active agents
DE10031703A1 (de) 2000-06-29 2002-01-10 Beiersdorf Ag Verwendung von Calcium freisetzenden oder bindenden Substanzen zur gezielten Schächung oder Stärkung der Barrierefunktion der Haut
EP1170015A1 (de) 2000-07-06 2002-01-09 Laboratoires Serobiologiques(Societe Anonyme) Verwendung von Extrakten des Pilzes Grifola frondosa
DE10033022A1 (de) 2000-07-07 2002-01-17 Cognis Deutschland Gmbh Aerosole
DE10034619A1 (de) 2000-07-17 2002-01-31 Cognis Deutschland Gmbh Aniontensidfreie niedrigviskose Trübungsmittel
DE10036655A1 (de) 2000-07-26 2002-02-07 Basf Ag Kosmetische oder dermatologische Zubereitungen zur Vermeidung von Hautschädigungen durch Peroxide
DE10036799A1 (de) 2000-07-28 2002-02-07 Beiersdorf Ag Neues Mittel zur Behandlung der Haare und der Kopfhaut
US7198801B2 (en) 2000-08-03 2007-04-03 Antares Pharma Ipl Ag Formulations for transdermal or transmucosal application
FR2813195B1 (fr) 2000-08-29 2003-04-04 Serobiologiques Lab Sa Utilisation d'extraits de la plante cassia alata dans des produits de soin
DE10048260A1 (de) 2000-09-29 2002-04-11 Beiersdorf Ag Kosmetische oder dermatologische Zubereitungen mit einem Gehalt an Aminoguanidin und/oder dessen Derivaten und Strukturanaloga zur Hautaufhellung von Altersflecken und/oder zur Verhinderung der Hautbräunung, insbesondere der durch UV-Strahlung hervorgerufenen Hautbräunung
DE10053328A1 (de) 2000-10-27 2002-05-08 Cognis Deutschland Gmbh Kosmetische Zubereitungen
US20070003536A1 (en) 2000-11-21 2007-01-04 Zimmerman Amy C Topical skin compositions, their preparation, and their use
DE10064818A1 (de) 2000-12-22 2002-06-27 Basf Ag Verwendung von Chroman-Derivaten in kosmetischen oder dermatologischen Zubreitungen
US6806069B2 (en) 2001-01-09 2004-10-19 Pharmachem Laboratories, Inc. Ubiquinone composition and methods related thereto
FR2819414A1 (fr) 2001-01-15 2002-07-19 Cognis France Sa Preparations cosmetiques et/ou pharmaceutiques comprenant des extraits de plantes dites a resurrection
NL1017205C2 (nl) 2001-01-26 2002-07-29 Adriaan Emanuel Hendricus Wiel Medicinale en cosmetische toepassing van hop en co-enzym Q10.
DE10113046A1 (de) 2001-03-15 2002-09-26 Beiersdorf Ag Selbstschäumende schaumförmige Zubereitungen mit organischen Hydrokolliden und partikulären hydrophobisierten und/oder ölabsorbierenden Festkörpersubstanzen
DE10113053A1 (de) 2001-03-15 2002-09-19 Beiersdorf Ag Selbstschäumende oder schaumförmige Zubereitungen mit anorganischen Gelbildnern und organischen Hydrololloiden
DE10113050A1 (de) 2001-03-15 2002-09-19 Beiersdorf Ag Selbstschäumende oder schaumförmige Zubereitungen organischen Hydrokolloiden
EP1243252B1 (fr) 2001-03-23 2006-05-24 L'oreal Composition pour le peau, contenant des fibres et des ubiquinones
US20030031688A1 (en) 2001-04-02 2003-02-13 Dipak Ghosh Cosmetic composition with improved skin moisturizing properties
US6727234B2 (en) 2001-04-03 2004-04-27 University Of Iowa Research Foundation Isoprenoid analog compounds and methods of making and use thereof
DE10118269A1 (de) 2001-04-12 2002-10-17 Cognis Deutschland Gmbh Kosmetische Zubereitungen
US6686485B2 (en) 2001-04-19 2004-02-03 Daniel David West Synthesis of coenzyme Q10, ubiquinone
US6582723B2 (en) 2001-05-03 2003-06-24 Wayne F. Gorsek Cancer immune composition for prevention and treatment of individuals
JP3742602B2 (ja) 2001-05-09 2006-02-08 株式会社カネカ 還元型補酵素ｑの安定な溶液
JP4603192B2 (ja) 2001-05-10 2010-12-22 株式会社カネカ 毛髪頭皮用組成物
DE10123771B4 (de) 2001-05-16 2019-01-10 Beiersdorf Ag Verwendung von Elektrolyten zur Stärkung der Barrierefunktion der Haut
EP1260212A1 (de) 2001-05-21 2002-11-27 Cognis France S.A. Kosmetische Mittel
EP1262167A1 (de) 2001-06-01 2002-12-04 Cognis France S.A. Kosmetische Zubereitungen enthaltend ein Extrakt von keimenden Pflanzen
US7091241B2 (en) 2001-06-01 2006-08-15 Summa Health System Nontoxic potentiation/sensitization of cancer therapy by supplementary treatment with combined vitamins C and K3
US6506915B1 (en) 2001-06-14 2003-01-14 Daniel David West Synthesis of coenzyme Q10 ubiquinone
FR2826017B1 (fr) 2001-06-15 2004-06-11 Cognis France Sa Melanges de tensioactifs
SE0102380D0 (sv) 2001-07-02 2001-07-02 Macronova Ab Kräm för behandling av åldersförändringar i huden hos människa
DE10133198A1 (de) 2001-07-07 2003-01-23 Beiersdorf Ag Kreatin enthaltende kosmetische und dermatologische Zubereitungen zur Behandlung und aktiven Prävention trockener Haut und anderer negativer Veränderungen der physiologischen Homöostase der gesunden Haut
JP2003020495A (ja) 2001-07-10 2003-01-24 Cognis Japan Ltd 油脂組成物
CH695085A5 (de) 2001-07-13 2005-12-15 Mibelle Ag Cosmetics Formulierungen zur Pflege der Haut nach Laserbehandlungen und/oder chemischen Peelings und Verwendung der Formulierungen.
TWI235146B (en) 2001-07-16 2005-07-01 Kaneka Corp Method of stabilizing reduced coenzyme q10 and method of acidic crystallization
EP1411951B2 (en) 2001-07-27 2010-11-10 N.V. Nutricia Enteral compositions for the prevention and/or treatment of sepsis
EP1281392A1 (de) 2001-08-02 2003-02-05 Cognis France S.A. Kosmetische und/oder pharmaceutische Zubereitungen enthaltend Pflanzenextrakte
DE10139580A1 (de) 2001-08-10 2003-02-20 Beiersdorf Ag Kosmetische und dermatologische Zubereitungen in Form von O/W-Emulsionen mit einem Gehalt an Sterinen und/oder C12-C40-Fettsäuren
DE10143963A1 (de) 2001-09-07 2003-03-27 Basf Ag Kosmetische und dermatologische Zubereitungen in Form von W/O-Emulsionen, enthaltend ein aminosubstituiertes Hydroxybenzophenon
DE10143962A1 (de) 2001-09-07 2003-03-27 Basf Ag Kosmetische und dermatologische Zubereitungen in Form von O/W-Emulsionen, enthaltend ein aminosubstituiertes Hydroxybenzophenon
DE10143964A1 (de) 2001-09-07 2003-03-27 Basf Ag Emulgatorarme oder emulgatorfreie Systeme vom Typ Öl-in-Wasser mit einem Gehalt an Stabilisatoren und einem aminosubstituierten Hydroxybenzophenon
AU2002339555B2 (en) 2001-09-18 2007-03-01 Ciba Specialty Chemicals Holding Inc. Use of guaiol for treating the skin
DE10150725A1 (de) 2001-10-13 2003-04-17 Cognis Deutschland Gmbh Aniontensidfreie niedrigviskose Trübungsmittel
US7560123B2 (en) 2004-08-12 2009-07-14 Everett Laboratories, Inc. Compositions and methods for nutrition supplementation
US20060039956A1 (en) 2001-10-26 2006-02-23 Hermann Hensen Impregnating solution for cosmetic cloths
US6753325B2 (en) 2001-11-06 2004-06-22 The Quigley Corporation Composition and method for prevention, reduction and treatment of radiation dermatitis
US20030105031A1 (en) 2001-11-06 2003-06-05 Rosenbloom Richard A. Methods for the treatment of skin disorders
DE10155769A1 (de) 2001-11-14 2003-05-22 Cognis Deutschland Gmbh Kosmetische und/oder pharmazeutische Emulsionen
DE10160682A1 (de) 2001-12-11 2003-06-18 Cognis Deutschland Gmbh Emollients und kosmetische Zusammensetzungen
US6652891B2 (en) 2001-12-12 2003-11-25 Herbasway Laboratories, Llc Co-enzyme Q10 dietary supplement
DE10162026A1 (de) 2001-12-18 2003-07-03 Cognis Deutschland Gmbh Hochkonzentriert fließfähige Perlglanzkonzentrate
DE10162351A1 (de) 2001-12-18 2003-07-03 Cognis Deutschland Gmbh Kosmetische und/oder pharmazeutische Emulsionen
ITRM20010755A1 (it) 2001-12-20 2003-06-20 Simonelli Giuseppe Uso del chinone q10 per il trattamento delle malattie oculari.
US20030129253A1 (en) 2002-01-03 2003-07-10 Milley Christopher J. Stable aqueous suspension
MXPA04006489A (es) 2002-01-18 2004-10-04 Basf Ag Preparaciones cosmeticas y dermatologicas para evitar danos cutaneos causados por peroxidos.
TW200302056A (en) 2002-01-18 2003-08-01 Kaneka Corp Method for stabilizing reduced coenzyme Q10 and composition therefor
US7357918B2 (en) 2002-01-31 2008-04-15 Ciba Specialty Chemicals Corp. Micropigment mixtures
ES2269978T3 (es) 2002-02-12 2007-04-01 Dsm Ip Assets B.V. Composiciones para filtros solares asi como dihidropiridinas y dihidropiranos.
WO2003068008A1 (en) 2002-02-14 2003-08-21 Dsm Ip Assets B.V. Water-dispersible coenzyme q10 dry powders
EP1340486A1 (de) 2002-03-01 2003-09-03 Cognis France S.A. Verwendung von Zuckerestern
US20030167556A1 (en) * 2002-03-05 2003-09-11 Consumers Choice Systems, Inc. Methods and devices for transdermal delivery of anti-aging compounds for treatment and prevention of facial or neck skin aging
DE10254315A1 (de) 2002-03-15 2003-10-02 Cognis Deutschland Gmbh Emollients und kosmetische Zubereitungen
DE10212528A1 (de) 2002-03-21 2003-10-02 Cognis Deutschland Gmbh Ölphasen für kosmetische Mittel
DE10213957A1 (de) 2002-03-28 2003-10-09 Beiersdorf Ag Vernetzte kosmetische oder pharmazeutische phospholipidhaltige Gele und Emulsionen auf der Basis von ethylenoxidhaltigen oder propylenoxidhaltigen Emulgatoren
US7811594B2 (en) 2002-03-28 2010-10-12 Beiersdorf Ag Crosslinked oil droplet-based cosmetic or pharmaceutical emulsions
DE10217474A1 (de) 2002-04-19 2003-11-06 Cognis Deutschland Gmbh Sonnenschutzemulsion mit Schaumspender
US20060193905A1 (en) 2002-05-14 2006-08-31 University Of Louisville Research Foundation, Inc. Direct cellular energy delivery system
CN100522245C (zh) * 2002-05-23 2009-08-05 Umd公司 用于穿粘膜的药物输送和冷冻保护的组合物
DE10223486A1 (de) 2002-05-27 2003-12-11 Beiersdorf Ag Kosmetische und/oder dermatologische Zubereitung mit 2,3-Dibenzylbutyrolactonen
ES2269955T3 (es) 2002-06-03 2007-04-01 Ciba Specialty Chemicals Holding Inc. Formulaciones para proteccion de uv.
DE10226018A1 (de) 2002-06-12 2003-12-24 Cognis Deutschland Gmbh Zubereitungen mit konjugiertem Linolalkohol
US7147841B2 (en) 2002-06-17 2006-12-12 Ciba Specialty Chemicals Corporation Formulation of UV absorbers by incorporation in solid lipid nanoparticles
WO2004003564A2 (de) 2002-06-26 2004-01-08 Europroteome Ag Tumormarker und ihre verwendung zur diagnose und therapie von tumorerkrankungen
US6953786B2 (en) 2002-10-01 2005-10-11 The Regents Of The University Of California Compositions comprising plant-derived polyphenolic compounds and inhibitors of reactive oxygen species and methods of using thereof
EP1421929A3 (de) 2002-11-21 2004-11-24 Cognis Deutschland GmbH & Co. KG Emollients und kosmetische Zubereitungen
DE10256881A1 (de) 2002-12-05 2004-06-24 Beiersdorf Ag Neue topische Verwendung von Bis-Arylimidazo[1,2-a]thiolanderivaten
US20040110848A1 (en) 2002-12-10 2004-06-10 Peffley Dennis M Method and kit for treating cancer
JP4671953B2 (ja) 2003-01-20 2011-04-20 チバ ホールディング インコーポレーテッド Ｕｖ吸収剤としてのトリアジン誘導体
WO2004069216A1 (en) 2003-02-03 2004-08-19 Dsm Ip Assets B.V. Novel stabilized cinnamic ester sunscreen compositions
US7258876B2 (en) 2003-02-05 2007-08-21 Craig Bozzacco Topical composition for treating infectious conditions of skin and mucosa
CN1208052C (zh) * 2003-03-20 2005-06-29 上海家化联合股份有限公司 一种辅酶q10前体脂质体及其制备方法
US7311897B2 (en) 2003-03-24 2007-12-25 Ciba Specialty Chemicals Corporation Symmetrical triazine derivatives
US7438903B2 (en) 2003-06-06 2008-10-21 Nbty, Inc. Methods and compositions that enhance bioavailability of coenzyme-Q10
US20050000726A1 (en) 2003-06-06 2005-01-06 Honda Motor Co., Ltd. Resin encapsulated electronic component unit and method of manufacturing the same
US20060035981A1 (en) 2003-08-02 2006-02-16 Mazzio Elizabeth A Inhibition of anaerobic glucose metabolism and corresponding composition as a natural non-toxic approach to cancer treatment
US20080069779A1 (en) 2003-08-04 2008-03-20 Foamix Ltd. Foamable vehicle and vitamin and flavonoid pharmaceutical compositions thereof
US20050036976A1 (en) 2003-08-12 2005-02-17 Joel Rubin Topical skin care composition
WO2005020940A1 (de) 2003-08-27 2005-03-10 Beiersdorf Ag Kapsel deren kapselhülle bei topischer anwendung nicht mehr gesondert warhnembar ist
US8124072B2 (en) 2003-09-29 2012-02-28 Soft Gel Technologies, Inc. Solubilized CoQ-10
WO2005032278A1 (en) 2003-09-29 2005-04-14 Soft Gel Technologies, Inc. SOLUBILIZED CoQ-10
US7169385B2 (en) 2003-09-29 2007-01-30 Ronald G. Udell Solubilized CoQ-10 and carnitine
BRPI0414858A (pt) 2003-10-02 2006-11-21 Sembiosys Genetics Inc métodos para preparação de corpos de óleo compreendendo ingredientes ativos
DE10347218A1 (de) 2003-10-10 2005-05-12 Cognis Deutschland Gmbh Sonnenschutzmittel
DE10347940A1 (de) 2003-10-15 2005-05-19 Cognis Deutschland Gmbh & Co. Kg Selbstemulgierende Zubereitungen
EP1681053B1 (en) 2003-10-31 2014-10-08 Kaneka Corporation Composition containing clathrated reduced coenzyme Q
CN1874751A (zh) 2003-11-05 2006-12-06 Dsmip资产公司 紫外线滤光材料总量降低的且含聚硅氧烷类紫外线滤光材料的光防护组合物
US20050100537A1 (en) 2003-11-10 2005-05-12 Evans Gregory S. Methods and kits for reducing cellular damage, inhibiting free radical production, and scavenging free radicals in mammals
DE10354052A1 (de) 2003-11-17 2005-06-16 Beiersdorf Ag Kosmetikum mit empfindlichen Inhaltsstoffen
EP1718283B1 (en) 2004-01-22 2013-03-06 University of Miami Topical co-enzyme q10 formulations and methods of use
US20050226947A1 (en) 2004-02-04 2005-10-13 Dale Kern Agents for sequestering serum aging factors and uses therefore
CN1942178A (zh) 2004-02-19 2007-04-04 奥克塞尔公司 用于治疗皮肤疾病的局部制剂
US7780873B2 (en) 2004-02-23 2010-08-24 Texas A&M University System Bioactive complexes compositions and methods of use thereof
DE102004014615A1 (de) 2004-03-23 2005-10-13 Beiersdorf Ag Taurinhaltige Zubereitungen zur Verbesserung der Hautbarriere
EP1734915A2 (en) 2004-04-06 2006-12-27 Basf Aktiengesellschaft COSMETIC FORMULATIONS COMPRISING ZnO NANOPARTICLES
US20050226858A1 (en) 2004-04-09 2005-10-13 Kaneka Corporation Compositions containing reduced coenzyme Q10 and carotenoid
US7723569B2 (en) 2004-04-30 2010-05-25 National Institute Of Agrobiological Sciences Method for producing ubiquinone-10 in plant
RU2375053C2 (ru) 2004-05-18 2009-12-10 Кемийски Инштитут Новая водорастворимая форма коэнзима q10 в форме комплекса включения с бета-циклодекстрином, способ ее получения и ее применение
WO2005115306A2 (de) 2004-05-24 2005-12-08 Basf Aktiengesellschaft Keratin-bindende polypeptide
US7906140B2 (en) * 2004-06-17 2011-03-15 Virun, Inc. Compositions for mucosal delivery of agents
DE602005011437D1 (de) 2004-06-18 2009-01-15 Symrise Gmbh & Co Kg Brombeerextrakt
WO2006000350A2 (en) 2004-06-28 2006-01-05 Dsm Ip Assets B.V. Cosmetic compositions containing protein hydrolysates
JP2006070016A (ja) 2004-08-02 2006-03-16 Kaneka Corp 還元型補酵素ｑを含有する美白用組成物
US20060051462A1 (en) 2004-09-03 2006-03-09 Wang Jimmy X Self emulsifying compositions for delivering lipophilic coenzyme Q10 and other dietary ingredients
US7288263B2 (en) * 2004-09-13 2007-10-30 Evera Laboratories, Llc Compositions and methods for treatment of skin discoloration
WO2006044738A2 (en) 2004-10-18 2006-04-27 Maroon Biotech Corporation Methods and compositions for treatment of free radical injury
US8828365B2 (en) 2004-11-02 2014-09-09 Dsm Ip Assets B.V. Additive for UV-sunscreen preparations
GB0424891D0 (en) 2004-11-11 2004-12-15 Boots Co Plc Topical compositions
US20060127384A1 (en) 2004-12-09 2006-06-15 Sergio Capaccioli Coenzyme Q10 as antiapoptotic agent
NO20045674D0 (no) 2004-12-28 2004-12-28 Uni I Oslo Thin films prepared with gas phase deposition technique
US20060286046A1 (en) 2005-01-05 2006-12-21 Haber C Andrew Skin care compositions
US20080207560A1 (en) * 2005-01-07 2008-08-28 Ayako Harada Composition For External Use
WO2006073190A1 (ja) * 2005-01-07 2006-07-13 Rohto Pharmaceutical Co., Ltd. 外用組成物
US20060188492A1 (en) 2005-01-13 2006-08-24 Chronorx Llc, An Alaska Limited Liability Company Topical management of ocular and periocular conditions
DE102005007980A1 (de) 2005-02-22 2006-02-23 Clariant Gmbh Kosmetische, pharmazeutische oder dermatologische Zubereitungen enthaltend Copolymerwachse
US20060251690A1 (en) 2005-04-01 2006-11-09 Zymes, Llc Skin enrichment using CoQ10 as the delivery system
US20070053985A1 (en) 2005-08-24 2007-03-08 Kaneka Corporation Coenzyme Q10-containing fine particle with excellent dispersibility
US20070071779A1 (en) 2005-09-26 2007-03-29 Leggit Ingenuity, Llc Compositions for delivering lipophilic agents to the intestinal mucosa and method of making thereof
US20070092469A1 (en) 2005-10-26 2007-04-26 Eric Jacobs Topically applied Glucosamine Sulfate and all its related, precursor, and derivative compounds significantly increases the skin's natural produciton of hyaluronic acid for the rejuvenation of healthier younger-looking skin; while PhosphatidylCholine is required to replace its deficiency caused by topical Dimethylaminoethanol (DMAE)
US8506956B2 (en) 2005-10-31 2013-08-13 Kaneka Corporation Method for stabilizing reduced coenzyme Q10
US9265792B2 (en) 2005-11-16 2016-02-23 Patricia A. Riley Integument cell regeneration formulation
AU2006339607A1 (en) 2005-12-02 2007-09-13 Sirtris Pharmaceuticals, Inc. Modulators of Cdc2-like kinases (Clks) and methods of use thereof
US20070172436A1 (en) 2006-01-23 2007-07-26 Jerry Zhang Nonaqueous ascorbic acid compositions and methods for preparing same
US20070184076A1 (en) 2006-02-07 2007-08-09 Unger Evan C Liquid-filled nanodroplets for anti-cancer therapy
US20070184041A1 (en) 2006-02-09 2007-08-09 Burja Adam M Methods and compositions related to production of coenzyme q10
US7335384B2 (en) 2006-03-17 2008-02-26 4K Nutripharma International Nutrient compositions for the treatment and prevention of inflammation and disorders associated therewith
EP2025662A4 (en) 2006-04-28 2011-07-27 Kaneka Corp PROCESS FOR PURIFYING REDUCED COENZYME Q10
US8021659B2 (en) 2006-04-28 2011-09-20 Naidu Lp Coenzyme Q10, lactoferrin and angiogenin compositions and uses thereof
ES2639567T3 (es) 2006-04-28 2017-10-27 Kaneka Corporation Método para la estabilización de la coenzima reducida Q10
US20080020022A1 (en) 2006-06-05 2008-01-24 Udell Ronald G Chewable co-enzyme q-10 capsule
US8894993B2 (en) 2006-08-04 2014-11-25 Natreon Inc. Mitochondria-targeted antioxidants
WO2010132507A2 (en) * 2009-05-11 2010-11-18 Cytotech Labs, Llc Methods for treatment of disease using an epimetabolic shifter (coenzyme q10)

Also Published As

Publication number Publication date
MX2009010170A (es) 2009-11-26
AU2014202278B2 (en) 2016-06-02
AU2008228764B2 (en) 2014-05-08
MX363435B (es) 2019-03-22
AU2008228764A1 (en) 2008-09-25
AU2014202278A1 (en) 2014-05-22
US20130202683A1 (en) 2013-08-08
US8454945B2 (en) 2013-06-04
BRPI0809164B8 (pt) 2023-02-28
MX337408B (es) 2016-03-03
EP2136787A4 (en) 2013-07-31
US10588859B2 (en) 2020-03-17
CA2680825C (en) 2013-10-29
NO20093032L (no) 2009-10-22
ZA201400071B (en) 2014-12-23
CA2680825A1 (en) 2008-09-25
US20230147697A1 (en) 2023-05-11
BRPI0809164B1 (pt) 2020-08-04
CA2823407A1 (en) 2008-09-25
EP3607937A1 (en) 2020-02-12
WO2008116135A3 (en) 2008-12-24
EP2136787A2 (en) 2009-12-30
US20080233183A1 (en) 2008-09-25
CA2823407C (en) 2016-10-18
ES2755840T3 (es) 2020-04-23
EP2136787B1 (en) 2019-08-21
US20210015748A1 (en) 2021-01-21
WO2008116135A2 (en) 2008-09-25
AU2014202278C1 (en) 2017-04-13
BRPI0809164A2 (pt) 2014-09-16

Similar Documents

Publication Publication Date Title
MX363435B (es) Formulaciones topicas que tienen biodisponibilidad aumentada.
MY198422A (en) Pharmaceutical compositions comprising epa and a cardiovascular agent and methods of using the same
PH12016500216A1 (en) Stable pharmaceutical composition and methods of using same
CR10566A (es) Compuestos heterociclicos adecuados para el tratamiento de enfermedades relacionadas con nivel elevado de lipidos
SG178948A1 (en) Fatty acid niacin conjugates and their uses
IL197080A0 (en) Pyrimidone compounds as gsk-3 inhibitors
IN2012MN02591A (es)
WO2012075081A3 (en) High-strength testosterone undecanoate compositions
MY156288A (en) Pharmaceutical formulations containing dopamine receptor ligands.
MX363178B (es) Compuestos de carbohidratos con funcion de galactosa para el tratamiento de la nefropatia diabetica y de los trastornos asociados.
MX2009009428A (es) Analogos de ciclopamina heterociclicos y metodos de uso de los mismos.
MX2009003911A (es) Formulaciones de liberacion inmediata, mejoradas de topiramato.
MY167691A (en) A pharmaceutical spray composition comprising a vitamin d analogue and a corticosteroid
UA103930C2 (ru) Соединения и композиция для лечения паразитарных болезней
MY162499A (en) Methylphenidate-prodrugs, processes of making and using the same
UA96794C2 (ru) Глюкокортикоиды, способ их применения, способ лечения и фармацевтическая композиция на их основе
EP2099464A4 (en) LOCAL ADMINISTRATION OF GALLIUM COMPOSITIONS FOR PAIN TREATMENT
MX2013002118A (es) 2-oxi-quinolin-3-carboxamidas sustituidas como moduladores de kcnq2/3.
EP2114415A4 (en) METHOD AND COMPOUNDS FOR THE TARGETED RELEASE OF ACTIVE SUBSTANCES IN BONES FOR INTERACTION THEREOF
MX2012013607A (es) Polisacarido de las semillas de tamarindo para usarse en el tatamiento de enfermedades inflamatorias.
MX342459B (es) 2-oxo- y 2-tioxo-dihidroquinolin-3-carboxamidas sustituidas, como moduladores de kcnq2/3.
MX2013002295A (es) 1-oxo-dihidroisoquinolin-3-carboxamidas sustituidas como moduladores de kcnq2/3.
MX336980B (es) Combinacion y composicion para el tratamiento de obesidad.
MX2009002717A (es) Composiciones y metodos para tratamiento del sindrome de fatiga cronica y enfermedades neurodegenerativas.
TNSN08062A1 (en) Microparticle compositions of the topoisomerase i inhibitor 7-tert-butoxyiminomethylcamptothecin