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MX2010004281A - Composiciones y metodos para el tratamiento de la retinopatia diabetica. - Google Patents

Composiciones y metodos para el tratamiento de la retinopatia diabetica.

Info

Publication number
MX2010004281A
MX2010004281A MX2010004281A MX2010004281A MX2010004281A MX 2010004281 A MX2010004281 A MX 2010004281A MX 2010004281 A MX2010004281 A MX 2010004281A MX 2010004281 A MX2010004281 A MX 2010004281A MX 2010004281 A MX2010004281 A MX 2010004281A
Authority
MX
Mexico
Prior art keywords
diabetic retinopathy
treatment
methods
compositions
lfa
Prior art date
Application number
MX2010004281A
Other languages
English (en)
Inventor
John Burnier
Thomas Gadek
Charles Semba
Original Assignee
Sarcode Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sarcode Corp filed Critical Sarcode Corp
Publication of MX2010004281A publication Critical patent/MX2010004281A/es

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00Preparations for testing in vivo
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P41/00Drugs used in surgical methods, e.g. surgery adjuvants for preventing adhesion or for vitreum substitution
    • AHUMAN NECESSITIES
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    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F9/00Methods or devices for treatment of the eyes; Devices for putting in contact-lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
    • A61F9/0008Introducing ophthalmic products into the ocular cavity or retaining products therein
    • A61F9/0017Introducing ophthalmic products into the ocular cavity or retaining products therein implantable in, or in contact with, the eye, e.g. ocular inserts
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    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
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    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid or pantothenic acid
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    • A61K31/50Pyridazines; Hydrogenated pyridazines
    • A61K31/502Pyridazines; Hydrogenated pyridazines ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
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    • A61K31/505Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
    • A61K31/517Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
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    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
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    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
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    • G01N33/6893Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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    • C07K2317/92Affinity (KD), association rate (Ka), dissociation rate (Kd) or EC50 value
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    • G01N2800/164Retinal disorders, e.g. retinopathy
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
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Abstract

La presente invención proporciona compuestos y métodos para el tratamiento de la retinopatía diabética. En particular, se describen en la presente antagonistas LFA-1 para usarse en el tratamiento de la retinopatía diabética. Un aspecto de la invención proporciona el diagnóstico de la retinopatía diabética y la administración de un antagonista LFA-1, después de que el paciente es diagnosticado con retinopatía diabética.
MX2010004281A 2007-10-19 2008-10-17 Composiciones y metodos para el tratamiento de la retinopatia diabetica. MX2010004281A (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US99957107P 2007-10-19 2007-10-19
PCT/US2008/011878 WO2009054914A1 (en) 2007-10-19 2008-10-17 Compositions and methods for treatment of diabetic retinopathy

Publications (1)

Publication Number Publication Date
MX2010004281A true MX2010004281A (es) 2010-09-10

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Application Number Title Priority Date Filing Date
MX2010004281A MX2010004281A (es) 2007-10-19 2008-10-17 Composiciones y metodos para el tratamiento de la retinopatia diabetica.

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US (3) US20090155176A1 (es)
EP (3) EP3167886B1 (es)
JP (2) JP5808037B2 (es)
CN (1) CN101873797A (es)
AU (1) AU2008317473B2 (es)
CA (3) CA2702984C (es)
ES (2) ES2630406T3 (es)
MX (1) MX2010004281A (es)
WO (1) WO2009054914A1 (es)

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PT1881823E (pt) 2005-05-17 2015-03-02 Sarcode Bioscience Inc Composições e métodos para o tratamento de transtornos oculares
MX2010004281A (es) 2007-10-19 2010-09-10 Sarcode Corp Composiciones y metodos para el tratamiento de la retinopatia diabetica.
CN102056485A (zh) * 2008-04-15 2011-05-11 萨可德公司 用于局部治疗免疫相关疾病的局部lfa-1拮抗剂
CN102065694A (zh) * 2008-04-15 2011-05-18 萨可德公司 用于局部治疗免疫相关疾病的雾化的lfa-1拮抗剂
US20090258069A1 (en) * 2008-04-15 2009-10-15 John Burnier Delivery of LFA-1 antagonists to the gastrointestinal system
US8080562B2 (en) 2008-04-15 2011-12-20 Sarcode Bioscience Inc. Crystalline pharmaceutical and methods of preparation and use thereof
WO2011050175A1 (en) 2009-10-21 2011-04-28 Sarcode Corporation Crystalline pharmaceutical and methods of preparation and use thereof
WO2011053801A2 (en) * 2009-10-30 2011-05-05 Intratus, Inc. Methods and cosmetic preparations for the sustained delivery of therapeutic agents to the eye
US20110189174A1 (en) * 2010-02-01 2011-08-04 Afshin Shafiee Compositions and methods for treating, reducing, ameliorating, alleviating, or inhibiting progression of, pathogenic ocular neovascularization
US8598156B2 (en) 2010-03-25 2013-12-03 Glaxosmithkline Llc Chemical compounds
UY33367A (es) * 2010-05-05 2011-10-31 Glaxo Wellcome Mfg Pte Ltd Composiciones farmacéuticas y métodos para su elaboración
HK1204988A1 (en) * 2012-02-22 2015-12-11 Stealth Peptides International, Inc. Methods and compositions for preventing or treating ophthalmic conditions
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US20090155176A1 (en) 2009-06-18
US20210338839A1 (en) 2021-11-04
WO2009054914A1 (en) 2009-04-30
EP2209371A4 (en) 2011-11-02
EP3797775A1 (en) 2021-03-31
AU2008317473B2 (en) 2014-07-17
EP2209371B1 (en) 2017-01-04
US10960087B2 (en) 2021-03-30
CN101873797A (zh) 2010-10-27
EP3167886B1 (en) 2020-08-05
JP2014221808A (ja) 2014-11-27
CA2958665C (en) 2021-03-02
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AU2008317473A1 (en) 2009-04-30
CA2702984A1 (en) 2009-04-30
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CA3105972A1 (en) 2009-04-30
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US20160220702A1 (en) 2016-08-04
ES2830024T3 (es) 2021-06-02

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