MX2010001086A - Nueva inmunoterapia contra tumores neuronales y cerebrales. - Google Patents
Nueva inmunoterapia contra tumores neuronales y cerebrales.Info
- Publication number
- MX2010001086A MX2010001086A MX2010001086A MX2010001086A MX2010001086A MX 2010001086 A MX2010001086 A MX 2010001086A MX 2010001086 A MX2010001086 A MX 2010001086A MX 2010001086 A MX2010001086 A MX 2010001086A MX 2010001086 A MX2010001086 A MX 2010001086A
- Authority
- MX
- Mexico
- Prior art keywords
- present
- relates
- brain tumors
- immunotherapy against
- tumors
- Prior art date
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
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- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- A61P37/04—Immunostimulants
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
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- C07K14/475—Growth factors; Growth regulators
- C07K14/495—Transforming growth factor [TGF]
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
- C07K14/7051—T-cell receptor (TcR)-CD3 complex
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- C07—ORGANIC CHEMISTRY
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- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/40—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
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- C07—ORGANIC CHEMISTRY
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- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
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- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
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- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
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- C12N5/06—Animal cells or tissues; Human cells or tissues
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- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
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- C12N9/0004—Oxidoreductases (1.)
- C12N9/0012—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7)
- C12N9/0036—Oxidoreductases (1.) acting on nitrogen containing compounds as donors (1.4, 1.5, 1.6, 1.7) acting on NADH or NADPH (1.6)
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- C12N9/10—Transferases (2.)
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- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
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- C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
- C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
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- C12Y208/00—Transferases transferring sulfur-containing groups (2.8)
- C12Y208/02—Sulfotransferases (2.8.2)
- C12Y208/02011—Galactosylceramide sulfotransferase (2.8.2.11)
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Abstract
La presente invenci?n hace referencia a p?ptidos, ?cidos nucleicos y c?lulas para su uso en m?todos inmunoterap?uticos. En particular, la presente invenci?n se refiere a la inmunoterapia del c?ncer. La presente invenci?n se refiere, adem?s, a ep?topos pept?dicos de linfocitos T citot?xicos (CTL) asociados a tumores, solos o en combinaci?n con otros p?ptidos asociados a tumores, que act?an como ingredientes activos de vacunas que estimulan las respuestas inmunol?gicas contra los tumores. La presente invenci?n se refiere a 11 novedosas secuencias pept?dicas y sus variantes derivadas de mol?culas HLA de clase I y II de c?lulas de tumor humanas, que pueden ser usadas en la composici?n de vacunas para provocar respuestas inmunol?gicas antitumorales.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07014797 | 2007-07-27 | ||
US95316107P | 2007-07-31 | 2007-07-31 | |
EP08005889.4A EP2105501B1 (en) | 2008-03-27 | 2008-03-27 | Novel immunotherapy against neuronal and brain tumors |
PCT/EP2008/006154 WO2009015843A1 (en) | 2007-07-27 | 2008-07-25 | Novel immunotherapy against neuronal and brain tumors |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2010001086A true MX2010001086A (es) | 2010-04-09 |
Family
ID=39720257
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010001086A MX2010001086A (es) | 2007-07-27 | 2008-07-25 | Nueva inmunoterapia contra tumores neuronales y cerebrales. |
Country Status (22)
Country | Link |
---|---|
US (6) | US9175040B2 (es) |
EP (2) | EP2183361B1 (es) |
JP (2) | JP6008461B2 (es) |
KR (2) | KR101290892B1 (es) |
CN (2) | CN101809148B (es) |
AU (1) | AU2008281015B2 (es) |
BR (1) | BRPI0813621A2 (es) |
CA (2) | CA2863010C (es) |
CY (1) | CY1117115T1 (es) |
DK (2) | DK2660248T3 (es) |
EA (2) | EA029831B1 (es) |
ES (2) | ES2543815T3 (es) |
HK (1) | HK1191022A1 (es) |
HR (2) | HRP20150820T1 (es) |
HU (1) | HUE027524T2 (es) |
MX (1) | MX2010001086A (es) |
NZ (2) | NZ582824A (es) |
PL (2) | PL2183361T3 (es) |
PT (2) | PT2660248E (es) |
RS (2) | RS54204B1 (es) |
SI (2) | SI2183361T1 (es) |
WO (1) | WO2009015843A1 (es) |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20090004213A1 (en) * | 2007-03-26 | 2009-01-01 | Immatics Biotechnologies Gmbh | Combination therapy using active immunotherapy |
MX2010001086A (es) | 2007-07-27 | 2010-04-09 | Immatics Biotechnologies Gmbh | Nueva inmunoterapia contra tumores neuronales y cerebrales. |
US9095541B2 (en) | 2009-11-24 | 2015-08-04 | Arch Cancer Therapeutics, Inc. | Brain tumor targeting peptides and methods |
US8530429B2 (en) | 2009-11-24 | 2013-09-10 | Arch Cancer Therapeutics, Inc. | Brain tumor targeting peptides and methods |
US8603485B2 (en) * | 2011-01-05 | 2013-12-10 | Wisconsin Alumni Research Foundation | Bystander immune suppression as a predictor for response to a vaccine |
GB201319446D0 (en) | 2013-11-04 | 2013-12-18 | Immatics Biotechnologies Gmbh | Personalized immunotherapy against several neuronal and brain tumors |
CN104698059B (zh) * | 2013-12-04 | 2017-07-21 | 苏州中赢医疗科技有限公司 | 一种脑胶质瘤肿瘤标志物及其应用 |
GB201501017D0 (en) * | 2014-12-23 | 2015-03-04 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers |
WO2016146143A1 (en) | 2015-03-16 | 2016-09-22 | Amal Therapeutics Sa | Cell penetrating peptides and complexes comprising the same |
TWI755158B (zh) * | 2015-03-17 | 2022-02-11 | 德商英麥提克生物技術股份有限公司 | 用於抗胰臟癌與其他癌症的免疫治療的新穎胜肽及胜肽的組合 |
NL2014935B1 (en) | 2015-06-08 | 2017-02-03 | Applied Immune Tech Ltd | T cell receptor like antibodies having fine specificity. |
IL308735A (en) | 2015-07-01 | 2024-01-01 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers |
GB201511546D0 (en) | 2015-07-01 | 2015-08-12 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers |
MY188354A (en) | 2015-07-06 | 2021-12-02 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against esophageal cancer and other cancers |
GB201512369D0 (en) * | 2015-07-15 | 2015-08-19 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against epithelial ovarian cancer and other cancers |
GB201515321D0 (en) * | 2015-08-28 | 2015-10-14 | Immatics Biotechnologies Gmbh | Novel peptides, combination of peptides and scaffolds for use in immunotherapeutic treatment of various cancers |
MX2018007204A (es) | 2015-12-16 | 2018-12-11 | Gritstone Oncology Inc | Identificacion, fabricacion y uso de neoantigeno. |
LT3429618T (lt) | 2016-03-16 | 2024-05-10 | Amal Therapeutics Sa | Imuninės sistemos patikros taško moduliatoriaus ir komplekso, apimančio į ląsteles prasiskverbiantį peptidą, krovinį ir tlr peptido agonistą, derinys, skirtas naudoti medicinoje |
JP2019524773A (ja) * | 2016-08-02 | 2019-09-05 | ナントセル,インコーポレイテッド | 樹状細胞のトランスフェクション及びその方法 |
IL265479B (en) | 2016-09-21 | 2022-09-01 | Amal Therapeutics Sa | Fusion comprising a cell penetrating peptide, a multi epitope and a tlr peptide agonist for treatment of cancer |
KR102379955B1 (ko) | 2016-12-08 | 2022-03-29 | 이매틱스 바이오테크놀로지스 게엠베하 | 짝짓기가 향상된 t 세포 수용체 |
DE102016123893A1 (de) | 2016-12-08 | 2018-06-14 | Immatics Biotechnologies Gmbh | T-Zellrezeptoren mit verbesserter Bindung |
MX2019009070A (es) | 2017-02-01 | 2019-10-30 | Modernatx Inc | Composiciones de arnm terapeuticas inmunomoduladoras que codifican peptidos de mutacion de oncogenes de activacion. |
MX2019012225A (es) * | 2017-04-10 | 2019-12-09 | Immatics Biotechnologies Gmbh | Peptidos y combinaciones de los mismos para el uso en la inmunoterapia contra diversos tipos de cancer. |
WO2019075112A1 (en) | 2017-10-10 | 2019-04-18 | Gritstone Oncology, Inc. | IDENTIFICATION OF NEO-ANTIGENS USING HOT POINTS |
CA3083097A1 (en) | 2017-11-22 | 2019-05-31 | Gritstone Oncology, Inc. | Reducing junction epitope presentation for neoantigens |
WO2023049733A2 (en) * | 2021-09-21 | 2023-03-30 | The University Of Chicago | Methods and composition using patient-derived autologous neoantigens for treating cancer |
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