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CU20160060A7 - Péptidos, ácidos nucleicos y células, útiles en la inmunoterapia personalizada contra diversos tumores cerebrales y neuronales - Google Patents

Péptidos, ácidos nucleicos y células, útiles en la inmunoterapia personalizada contra diversos tumores cerebrales y neuronales

Info

Publication number
CU20160060A7
CU20160060A7 CUP2016000060A CU20160060A CU20160060A7 CU 20160060 A7 CU20160060 A7 CU 20160060A7 CU P2016000060 A CUP2016000060 A CU P2016000060A CU 20160060 A CU20160060 A CU 20160060A CU 20160060 A7 CU20160060 A7 CU 20160060A7
Authority
CU
Cuba
Prior art keywords
peptides
cells
present
nucleic acids
relates
Prior art date
Application number
CUP2016000060A
Other languages
English (en)
Inventor
Toni Weinschenk
Jens Fritsche
Steffen Walter
Norbert Hilf
Oliver Schorr
Harpreet Singh
Sabrina Kuttruff-Coqui
Colette Song
Original Assignee
Immatics Biotechnologies Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Immatics Biotechnologies Gmbh filed Critical Immatics Biotechnologies Gmbh
Publication of CU20160060A7 publication Critical patent/CU20160060A7/es

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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • A61K39/0011—Cancer antigens
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    • A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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Abstract

La presente invención se refiere a péptidos, ácidos nucleicos y células destinados a la utilización en métodos inmunoterapéuticos. En particular, Ia presente invención se refiere a Ia inmunoterapia contra el cáncer. La presente invención se refiere asimismo a epítopos peptídicos para linfocitos T citotóxicos (CTL) asociados a tumores, solos o en combinación con otros péptidos asociados a tumores que pueden servir como principios activos farmacéuticos en composiciones vacunales destinadas a estimular respuestas inmunitarias antitumorales. La presente invención se refiere específicamente a secuencias peptídicas y sus variantes derivadas de moléculas HLA de clase I y clase II de células tumorales humanas que pueden ser utilizadas en composiciones vacunales para desencadenar respuestas inmunitarias antitumorales.
CUP2016000060A 2013-11-04 2016-05-04 Péptidos, ácidos nucleicos y células, útiles en la inmunoterapia personalizada contra diversos tumores cerebrales y neuronales CU20160060A7 (es)

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US201361899680P 2013-11-04 2013-11-04
GBGB1319446.9A GB201319446D0 (en) 2013-11-04 2013-11-04 Personalized immunotherapy against several neuronal and brain tumors
PCT/EP2014/073588 WO2015063302A2 (en) 2013-11-04 2014-11-03 Personalized immunotherapy against several neuronal and brain tumors

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