MX2010001088A - Composicion de peptidos asociados a tumor y vacunas relacionadas contra el cancer. - Google Patents
Composicion de peptidos asociados a tumor y vacunas relacionadas contra el cancer.Info
- Publication number
- MX2010001088A MX2010001088A MX2010001088A MX2010001088A MX2010001088A MX 2010001088 A MX2010001088 A MX 2010001088A MX 2010001088 A MX2010001088 A MX 2010001088A MX 2010001088 A MX2010001088 A MX 2010001088A MX 2010001088 A MX2010001088 A MX 2010001088A
- Authority
- MX
- Mexico
- Prior art keywords
- tumor
- composition
- peptides
- present
- against cancer
- Prior art date
Links
- 206010028980 Neoplasm Diseases 0.000 title abstract 5
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 3
- 229960005486 vaccine Drugs 0.000 title abstract 3
- 201000011510 cancer Diseases 0.000 title 1
- 206010009944 Colon cancer Diseases 0.000 abstract 1
- 208000001333 Colorectal Neoplasms Diseases 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 230000005975 antitumor immune response Effects 0.000 abstract 1
- 238000002619 cancer immunotherapy Methods 0.000 abstract 1
- 210000002443 helper t lymphocyte Anatomy 0.000 abstract 1
- 230000028993 immune response Effects 0.000 abstract 1
- 230000001024 immunotherapeutic effect Effects 0.000 abstract 1
- 238000009169 immunotherapy Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/0005—Vertebrate antigens
- A61K39/0011—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
- A61K38/193—Colony stimulating factors [CSF]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/11—T-cells, e.g. tumour infiltrating lymphocytes [TIL] or regulatory T [Treg] cells; Lymphokine-activated killer [LAK] cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/10—Cellular immunotherapy characterised by the cell type used
- A61K40/19—Dendritic cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/20—Cellular immunotherapy characterised by the effect or the function of the cells
- A61K40/24—Antigen-presenting cells [APC]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K40/00—Cellular immunotherapy
- A61K40/40—Cellular immunotherapy characterised by antigens that are targeted or presented by cells of the immune system
- A61K40/41—Vertebrate antigens
- A61K40/42—Cancer antigens
- A61K40/4264—Cancer antigens from embryonic or fetal origin
- A61K40/4266—Carcinoembryonic antigen [CEA]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
- A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4748—Tumour specific antigens; Tumour rejection antigen precursors [TRAP], e.g. MAGE
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
- A61K2039/572—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2 cytotoxic response
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Genetics & Genomics (AREA)
- Mycology (AREA)
- Biophysics (AREA)
- Toxicology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Microbiology (AREA)
- Hematology (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
La presente invención se refiere a péptidos inmunoterapéuticos y su uso en inmunoterapia, en particular, en la inmunoterapia del cáncer. La presente invención describe epitopos peptídicos de linfocitos T colaboradores asociados a tumores, solos o en combinación con otros péptidos asociados a tumores, que actúan como ingredientes activos de vacunas que estimulan las respuestas inmunológicas contra los tumores. En particular, la composición de los péptidos de la presente invención puede usarse en composiciones de vacunas que provoquen respuestas inmunes antitumorales contra el cáncer colorrectal.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP07014796 | 2007-07-27 | ||
US95310907P | 2007-07-31 | 2007-07-31 | |
US98124107P | 2007-10-19 | 2007-10-19 | |
PCT/EP2008/006152 WO2009015841A1 (en) | 2007-07-27 | 2008-07-25 | Composition of tumour-associated peptides and related anti-cancer vaccine |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2010001088A true MX2010001088A (es) | 2010-06-01 |
Family
ID=39926464
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2010001088A MX2010001088A (es) | 2007-07-27 | 2008-07-25 | Composicion de peptidos asociados a tumor y vacunas relacionadas contra el cancer. |
Country Status (21)
Country | Link |
---|---|
US (1) | US7994276B2 (es) |
EP (2) | EP2178557B1 (es) |
JP (2) | JP5352586B2 (es) |
KR (1) | KR101167392B1 (es) |
CN (2) | CN101765434B (es) |
AU (1) | AU2008281013B2 (es) |
BR (1) | BRPI0814140A2 (es) |
CA (2) | CA2817054C (es) |
DK (1) | DK2567707T3 (es) |
EA (2) | EA018457B1 (es) |
ES (1) | ES2608583T3 (es) |
HK (1) | HK1182923A1 (es) |
HU (1) | HUE032379T2 (es) |
LT (1) | LT2567707T (es) |
MX (1) | MX2010001088A (es) |
NZ (1) | NZ582823A (es) |
PL (1) | PL2567707T3 (es) |
PT (1) | PT2567707T (es) |
SI (1) | SI2567707T1 (es) |
UA (2) | UA117216C2 (es) |
WO (1) | WO2009015841A1 (es) |
Families Citing this family (39)
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US20090004213A1 (en) * | 2007-03-26 | 2009-01-01 | Immatics Biotechnologies Gmbh | Combination therapy using active immunotherapy |
KR101167392B1 (ko) * | 2007-07-27 | 2012-07-19 | 이매틱스 바이오테크놀로지스 게엠베하 | 종양 관련 펩티드의 조성물 및 관련된 항암 백신 |
DK2119726T5 (en) * | 2008-05-14 | 2018-03-26 | Immatics Biotechnologies Gmbh | Novel and powerful MHC class II peptides derived from survivin and neurocan |
GB201004551D0 (en) * | 2010-03-19 | 2010-05-05 | Immatics Biotechnologies Gmbh | NOvel immunotherapy against several tumors including gastrointestinal and gastric cancer |
GB201019331D0 (en) * | 2010-03-19 | 2010-12-29 | Immatics Biotechnologies Gmbh | Methods for the diagnosis and treatment of cancer based on AVL9 |
GB201004575D0 (en) | 2010-03-19 | 2010-05-05 | Immatics Biotechnologies Gmbh | Composition of tumor associated peptides and related anti cancer vaccine for the treatment of gastric cancer and other cancers |
GB201009222D0 (en) | 2010-06-02 | 2010-07-21 | Immatics Biotechnologies Gmbh | Improved cancer therapy based on tumour associated antigens derived from cyclin D1 |
GB201021289D0 (en) * | 2010-12-15 | 2011-01-26 | Immatics Biotechnologies Gmbh | Novel biomarkers for a prediction of the outcome of an immunotherapy against cancer |
KR102020491B1 (ko) * | 2011-10-28 | 2019-09-10 | 온코세라피 사이언스 가부시키가이샤 | Topk 펩티드 및 이를 포함하는 백신 |
EP2847322B1 (en) * | 2012-05-08 | 2019-06-26 | Western University Of Health Sciences | Standardized ex vivo platforms for the antigen-specific expansion of cd4+ t cell populations |
GB201214007D0 (en) | 2012-08-07 | 2012-09-19 | Scancell Ltd | Anti-tumour immune responses to modified self-epitopes |
TWI777194B (zh) * | 2013-08-05 | 2022-09-11 | 德商伊瑪提克斯生物科技有限公司 | 新穎肽類,細胞及其用於治療多種腫瘤的用途,其製造方法及包含其等之醫藥組成物(一) |
EP3572510B1 (en) | 2013-11-21 | 2022-09-21 | Repertoire Genesis Incorporation | T cell receptor and b cell receptor repertoire analysis system, and use of same in treatment and diagnosis |
GB201501017D0 (en) * | 2014-12-23 | 2015-03-04 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against hepatocellular carcinoma (HCC) and other cancers |
WO2016112195A1 (en) | 2015-01-09 | 2016-07-14 | Etubics Corporation | Methods and compositions for combination immunotherapy |
CN104630145A (zh) * | 2015-01-12 | 2015-05-20 | 杨世成 | 一种抗肿瘤t细胞、其制备方法和抗肿瘤药物 |
TWI772927B (zh) * | 2015-03-31 | 2022-08-01 | 德商英麥提克生物技術股份有限公司 | 用於腎細胞癌(rcc)免疫治療的新型肽和肽組合物和支架 |
US11149087B2 (en) * | 2015-04-20 | 2021-10-19 | Etubics Corporation | Methods and compositions for combination immunotherapy |
CN104926944B (zh) * | 2015-05-22 | 2018-04-13 | 北京康爱瑞浩生物科技股份有限公司空港分公司 | 多靶点复合抗原负载cd8+细胞毒性t淋巴细胞的制备方法及其用途 |
NL2014935B1 (en) | 2015-06-08 | 2017-02-03 | Applied Immune Tech Ltd | T cell receptor like antibodies having fine specificity. |
GB201511191D0 (en) * | 2015-06-25 | 2015-08-12 | Immatics Biotechnologies Gmbh | T-cell epitopes for the immunotherapy of myeloma |
IL308735A (en) | 2015-07-01 | 2024-01-01 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers |
GB201511546D0 (en) | 2015-07-01 | 2015-08-12 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against ovarian cancer and other cancers |
GB201512703D0 (en) | 2015-07-20 | 2015-08-26 | Scancell Ltd | Anti-tumour immune responses to modified self-epitopes |
MX2018007204A (es) | 2015-12-16 | 2018-12-11 | Gritstone Oncology Inc | Identificacion, fabricacion y uso de neoantigeno. |
CN105586312A (zh) * | 2016-02-29 | 2016-05-18 | 时宏珍 | Hla-a0201限制性抗muc-1抗原特异性ctl的制备方法 |
JP2019533718A (ja) * | 2016-09-27 | 2019-11-21 | セレクタ バイオサイエンシーズ インコーポレーテッドSelecta Biosciences,Inc. | がんの処置における使用のための組換え免疫毒素 |
KR102379955B1 (ko) | 2016-12-08 | 2022-03-29 | 이매틱스 바이오테크놀로지스 게엠베하 | 짝짓기가 향상된 t 세포 수용체 |
DE102016123893A1 (de) | 2016-12-08 | 2018-06-14 | Immatics Biotechnologies Gmbh | T-Zellrezeptoren mit verbesserter Bindung |
ES2963635T3 (es) * | 2017-03-28 | 2024-04-01 | Ohio State Innovation Foundation | Vacunas de péptido PD1 humano y usos de las mismas |
MX2019012225A (es) * | 2017-04-10 | 2019-12-09 | Immatics Biotechnologies Gmbh | Peptidos y combinaciones de los mismos para el uso en la inmunoterapia contra diversos tipos de cancer. |
PE20191617A1 (es) * | 2017-04-10 | 2019-11-05 | Immatics Biotechnologies Gmbh | Peptidos y combinaciones de peptidos para el uso en la inmunoterapia contra la leucemia y otros tipos de cancer |
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CN111363009B (zh) * | 2020-03-18 | 2020-10-30 | 北京鼎成肽源生物技术有限公司 | 一种直肠癌靶标抗原及其刺激培养的ctl细胞及其应用 |
CN111617238B (zh) * | 2020-06-02 | 2022-12-13 | 苏州药明康德新药开发有限公司 | 小鼠ct26结直肠癌治疗性肿瘤多肽疫苗制剂及其制备方法 |
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KR101167392B1 (ko) * | 2007-07-27 | 2012-07-19 | 이매틱스 바이오테크놀로지스 게엠베하 | 종양 관련 펩티드의 조성물 및 관련된 항암 백신 |
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DK2119726T5 (en) * | 2008-05-14 | 2018-03-26 | Immatics Biotechnologies Gmbh | Novel and powerful MHC class II peptides derived from survivin and neurocan |
-
2008
- 2008-07-25 KR KR1020107001771A patent/KR101167392B1/ko not_active IP Right Cessation
- 2008-07-25 EP EP08785105.1A patent/EP2178557B1/en active Active
- 2008-07-25 LT LTEP12187307.9T patent/LT2567707T/lt unknown
- 2008-07-25 US US12/180,113 patent/US7994276B2/en active Active
- 2008-07-25 EA EA201000208A patent/EA018457B1/ru not_active IP Right Cessation
- 2008-07-25 NZ NZ582823A patent/NZ582823A/en not_active IP Right Cessation
- 2008-07-25 ES ES12187307.9T patent/ES2608583T3/es active Active
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