KR950702186A - 신규한 니코틴산 에스테르(novel nicotinic acid esters) - Google Patents
신규한 니코틴산 에스테르(novel nicotinic acid esters)Info
- Publication number
- KR950702186A KR950702186A KR1019940704643A KR19940704643A KR950702186A KR 950702186 A KR950702186 A KR 950702186A KR 1019940704643 A KR1019940704643 A KR 1019940704643A KR 19940704643 A KR19940704643 A KR 19940704643A KR 950702186 A KR950702186 A KR 950702186A
- Authority
- KR
- South Korea
- Prior art keywords
- acid esters
- nicotinic acid
- saturated
- carbon atoms
- compounds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical class OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 title 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 229920006395 saturated elastomer Polymers 0.000 abstract 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 229910052799 carbon Inorganic materials 0.000 abstract 1
- 210000003169 central nervous system Anatomy 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002391 heterocyclic compounds Chemical class 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000004950 trifluoroalkyl group Chemical group 0.000 abstract 1
- 125000004417 unsaturated alkyl group Chemical group 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Psychiatry (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Pyridine Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9201956A SE9201956D0 (sv) | 1992-06-25 | 1992-06-25 | Novel nicotinicacid esters |
| SE9201956-1 | 1992-06-25 | ||
| PCT/SE1993/000565 WO1994000434A1 (en) | 1992-06-25 | 1993-06-23 | Novel nicotinic acid esters |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| KR950702186A true KR950702186A (ko) | 1995-06-19 |
| KR100302216B1 KR100302216B1 (ko) | 2001-11-22 |
Family
ID=20386602
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| KR1019940704643A Expired - Fee Related KR100302216B1 (ko) | 1992-06-25 | 1993-06-23 | 새로운니코틴산에스테르화합물및그제조방법 |
Country Status (27)
| Country | Link |
|---|---|
| US (1) | US5658910A (ko) |
| EP (2) | EP1120410B1 (ko) |
| JP (1) | JP3306827B2 (ko) |
| KR (1) | KR100302216B1 (ko) |
| CN (1) | CN1085981C (ko) |
| AT (2) | ATE209634T1 (ko) |
| AU (1) | AU681346B2 (ko) |
| BG (1) | BG62000B1 (ko) |
| CA (1) | CA2139112C (ko) |
| CZ (1) | CZ281975B6 (ko) |
| DE (2) | DE69331234T2 (ko) |
| DK (1) | DK0673368T3 (ko) |
| EE (1) | EE03122B1 (ko) |
| ES (1) | ES2169044T3 (ko) |
| FI (1) | FI107151B (ko) |
| HU (2) | HU220613B1 (ko) |
| IL (1) | IL106135A (ko) |
| NO (1) | NO302945B1 (ko) |
| NZ (1) | NZ253823A (ko) |
| PH (1) | PH31417A (ko) |
| PT (1) | PT673368E (ko) |
| RO (1) | RO115725B1 (ko) |
| RU (1) | RU2127732C1 (ko) |
| SE (1) | SE9201956D0 (ko) |
| SK (1) | SK279393B6 (ko) |
| WO (1) | WO1994000434A1 (ko) |
| ZA (1) | ZA934596B (ko) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6632823B1 (en) * | 1997-12-22 | 2003-10-14 | Merck & Co., Inc. | Substituted pyridine compounds useful as modulators of acetylcholine receptors |
| US7045519B2 (en) * | 1998-06-19 | 2006-05-16 | Chiron Corporation | Inhibitors of glycogen synthase kinase 3 |
| AU4956699A (en) | 1998-06-19 | 2000-01-05 | Chiron Corporation | Inhibitors of glycogen synthase kinase 3 |
| AU2019265268C1 (en) | 2018-05-09 | 2022-08-04 | Lg Chem, Ltd. | Novel compound exhibiting enteropeptidase inhibitory activity |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SE8701375D0 (sv) * | 1987-04-02 | 1987-04-02 | Leo Ab | Novel pyridyl- and pyrimidyl derivatives |
| SE9201239D0 (sv) * | 1992-04-21 | 1992-04-21 | Kabi Pharmacia Ab | Agents for treating substance abuse disorders |
| SE9202265D0 (sv) * | 1992-07-31 | 1992-07-31 | Kabi Pharmacia Ab | Novel- pyridyl and pyrimidylpiperazine derivatives |
-
1992
- 1992-06-25 SE SE9201956A patent/SE9201956D0/xx unknown
-
1993
- 1993-06-23 DK DK93915075T patent/DK0673368T3/da active
- 1993-06-23 HU HU9403786A patent/HU220613B1/hu not_active IP Right Cessation
- 1993-06-23 WO PCT/SE1993/000565 patent/WO1994000434A1/en active IP Right Grant
- 1993-06-23 EP EP01108668A patent/EP1120410B1/en not_active Expired - Lifetime
- 1993-06-23 DE DE69331234T patent/DE69331234T2/de not_active Expired - Fee Related
- 1993-06-23 EP EP93915075A patent/EP0673368B1/en not_active Expired - Lifetime
- 1993-06-23 ES ES93915075T patent/ES2169044T3/es not_active Expired - Lifetime
- 1993-06-23 SK SK1585-94A patent/SK279393B6/sk not_active IP Right Cessation
- 1993-06-23 US US08/362,475 patent/US5658910A/en not_active Expired - Lifetime
- 1993-06-23 AT AT93915075T patent/ATE209634T1/de not_active IP Right Cessation
- 1993-06-23 NZ NZ253823A patent/NZ253823A/en not_active IP Right Cessation
- 1993-06-23 CZ CZ943274A patent/CZ281975B6/cs not_active IP Right Cessation
- 1993-06-23 KR KR1019940704643A patent/KR100302216B1/ko not_active Expired - Fee Related
- 1993-06-23 AT AT01108668T patent/ATE278671T1/de not_active IP Right Cessation
- 1993-06-23 JP JP50226894A patent/JP3306827B2/ja not_active Expired - Fee Related
- 1993-06-23 AU AU45193/93A patent/AU681346B2/en not_active Ceased
- 1993-06-23 CA CA002139112A patent/CA2139112C/en not_active Expired - Fee Related
- 1993-06-23 RO RO94-02087A patent/RO115725B1/ro unknown
- 1993-06-23 DE DE69333655T patent/DE69333655D1/de not_active Expired - Lifetime
- 1993-06-23 RU RU94046310A patent/RU2127732C1/ru not_active IP Right Cessation
- 1993-06-23 PT PT93915075T patent/PT673368E/pt unknown
- 1993-06-24 IL IL10613593A patent/IL106135A/en not_active IP Right Cessation
- 1993-06-25 ZA ZA934596A patent/ZA934596B/xx unknown
- 1993-06-25 CN CN93116250A patent/CN1085981C/zh not_active Expired - Fee Related
-
1994
- 1994-11-17 EE EE9400400A patent/EE03122B1/xx not_active IP Right Cessation
- 1994-12-22 BG BG99289A patent/BG62000B1/bg unknown
- 1994-12-23 FI FI946085A patent/FI107151B/fi active
- 1994-12-23 NO NO945022A patent/NO302945B1/no not_active IP Right Cessation
-
1995
- 1995-05-23 HU HU95P/P00139P patent/HU210875A9/hu unknown
-
1998
- 1998-06-24 PH PH4640898A patent/PH31417A/en unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PA0105 | International application |
Patent event date: 19941219 Patent event code: PA01051R01D Comment text: International Patent Application |
|
| N231 | Notification of change of applicant | ||
| PN2301 | Change of applicant |
Patent event date: 19950127 Comment text: Notification of Change of Applicant Patent event code: PN23011R01D |
|
| PG1501 | Laying open of application | ||
| A201 | Request for examination | ||
| PA0201 | Request for examination |
Patent event code: PA02012R01D Patent event date: 19980622 Comment text: Request for Examination of Application |
|
| E902 | Notification of reason for refusal | ||
| PE0902 | Notice of grounds for rejection |
Comment text: Notification of reason for refusal Patent event date: 20000531 Patent event code: PE09021S01D |
|
| E701 | Decision to grant or registration of patent right | ||
| PE0701 | Decision of registration |
Patent event code: PE07011S01D Comment text: Decision to Grant Registration Patent event date: 20010402 |
|
| GRNT | Written decision to grant | ||
| PR0701 | Registration of establishment |
Comment text: Registration of Establishment Patent event date: 20010702 Patent event code: PR07011E01D |
|
| PR1002 | Payment of registration fee |
Payment date: 20010702 End annual number: 3 Start annual number: 1 |
|
| PG1601 | Publication of registration | ||
| LAPS | Lapse due to unpaid annual fee | ||
| PC1903 | Unpaid annual fee |
Termination category: Default of registration fee Termination date: 20050409 |