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FI946085L - Uusia nikotiinihappoestereitä - Google Patents

Uusia nikotiinihappoestereitä Download PDF

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Publication number
FI946085L
FI946085L FI946085A FI946085A FI946085L FI 946085 L FI946085 L FI 946085L FI 946085 A FI946085 A FI 946085A FI 946085 A FI946085 A FI 946085A FI 946085 L FI946085 L FI 946085L
Authority
FI
Finland
Prior art keywords
acid esters
nicotinic acid
new nicotinic
new
esters
Prior art date
Application number
FI946085A
Other languages
English (en)
Swedish (sv)
Other versions
FI107151B (fi
FI946085A0 (fi
Inventor
Torbjoern Lundstedt
Lisbeth Abramo
Anders Bjoerk
Goeran Pettersson
Gunnar Andersson
Curt Nordvi
Wu Jin Chang
Catarina Ludwig
Elisabeth Seifert
Arne Nilsson
Original Assignee
Pharmacia Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pharmacia Ab filed Critical Pharmacia Ab
Publication of FI946085A0 publication Critical patent/FI946085A0/fi
Publication of FI946085L publication Critical patent/FI946085L/fi
Application granted granted Critical
Publication of FI107151B publication Critical patent/FI107151B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79Acids; Esters
    • C07D213/80Acids; Esters in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, cocaine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
FI946085A 1992-06-25 1994-12-23 Menetelmä uusien terapeuttisesti käyttökelpoisten 2-[4-(4,4-bis(4-fluorifenyyli)butyyli)piperatsin-1-yyli]pyridin-3-yyli-karboksyyliestrereiden valmistamiseksi FI107151B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
SE9201956A SE9201956D0 (sv) 1992-06-25 1992-06-25 Novel nicotinicacid esters
SE9201956 1992-06-25
SE9300565 1993-02-22
PCT/SE1993/000565 WO1994000434A1 (en) 1992-06-25 1993-06-23 Novel nicotinic acid esters

Publications (3)

Publication Number Publication Date
FI946085A0 FI946085A0 (fi) 1994-12-23
FI946085L true FI946085L (fi) 1994-12-23
FI107151B FI107151B (fi) 2001-06-15

Family

ID=20386602

Family Applications (1)

Application Number Title Priority Date Filing Date
FI946085A FI107151B (fi) 1992-06-25 1994-12-23 Menetelmä uusien terapeuttisesti käyttökelpoisten 2-[4-(4,4-bis(4-fluorifenyyli)butyyli)piperatsin-1-yyli]pyridin-3-yyli-karboksyyliestrereiden valmistamiseksi

Country Status (27)

Country Link
US (1) US5658910A (fi)
EP (2) EP1120410B1 (fi)
JP (1) JP3306827B2 (fi)
KR (1) KR100302216B1 (fi)
CN (1) CN1085981C (fi)
AT (2) ATE209634T1 (fi)
AU (1) AU681346B2 (fi)
BG (1) BG62000B1 (fi)
CA (1) CA2139112C (fi)
CZ (1) CZ281975B6 (fi)
DE (2) DE69331234T2 (fi)
DK (1) DK0673368T3 (fi)
EE (1) EE03122B1 (fi)
ES (1) ES2169044T3 (fi)
FI (1) FI107151B (fi)
HU (2) HU220613B1 (fi)
IL (1) IL106135A (fi)
NO (1) NO302945B1 (fi)
NZ (1) NZ253823A (fi)
PH (1) PH31417A (fi)
PT (1) PT673368E (fi)
RO (1) RO115725B1 (fi)
RU (1) RU2127732C1 (fi)
SE (1) SE9201956D0 (fi)
SK (1) SK279393B6 (fi)
WO (1) WO1994000434A1 (fi)
ZA (1) ZA934596B (fi)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6632823B1 (en) * 1997-12-22 2003-10-14 Merck & Co., Inc. Substituted pyridine compounds useful as modulators of acetylcholine receptors
US7045519B2 (en) * 1998-06-19 2006-05-16 Chiron Corporation Inhibitors of glycogen synthase kinase 3
AU4956699A (en) 1998-06-19 2000-01-05 Chiron Corporation Inhibitors of glycogen synthase kinase 3
AU2019265268C1 (en) 2018-05-09 2022-08-04 Lg Chem, Ltd. Novel compound exhibiting enteropeptidase inhibitory activity

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8701375D0 (sv) * 1987-04-02 1987-04-02 Leo Ab Novel pyridyl- and pyrimidyl derivatives
SE9201239D0 (sv) * 1992-04-21 1992-04-21 Kabi Pharmacia Ab Agents for treating substance abuse disorders
SE9202265D0 (sv) * 1992-07-31 1992-07-31 Kabi Pharmacia Ab Novel- pyridyl and pyrimidylpiperazine derivatives

Also Published As

Publication number Publication date
EP0673368B1 (en) 2001-11-28
PH31417A (en) 1998-10-29
NO945022L (no) 1995-02-13
CA2139112C (en) 2006-03-21
HU9403786D0 (en) 1995-02-28
PT673368E (pt) 2002-05-31
JPH07508517A (ja) 1995-09-21
ZA934596B (en) 1994-02-14
HU220613B1 (hu) 2002-03-28
SE9201956D0 (sv) 1992-06-25
IL106135A (en) 1999-01-26
NO302945B1 (no) 1998-05-11
FI107151B (fi) 2001-06-15
HU210875A9 (en) 1995-08-28
EP1120410A1 (en) 2001-08-01
SK279393B6 (sk) 1998-11-04
CA2139112A1 (en) 1994-01-06
RO115725B1 (ro) 2000-05-30
FI946085A0 (fi) 1994-12-23
RU94046310A (ru) 1996-10-27
IL106135A0 (en) 1993-10-20
DE69331234T2 (de) 2002-08-08
DK0673368T3 (da) 2002-03-18
WO1994000434A1 (en) 1994-01-06
DE69331234D1 (de) 2002-01-10
EE03122B1 (et) 1998-10-15
NO945022D0 (no) 1994-12-23
KR100302216B1 (ko) 2001-11-22
BG99289A (bg) 1995-09-29
NZ253823A (en) 1996-01-26
EP0673368A1 (en) 1995-09-27
CZ327494A3 (en) 1995-09-13
HUT71406A (en) 1995-11-28
BG62000B1 (bg) 1998-12-30
JP3306827B2 (ja) 2002-07-24
AU4519393A (en) 1994-01-24
DE69333655D1 (de) 2004-11-11
KR950702186A (ko) 1995-06-19
ATE209634T1 (de) 2001-12-15
ATE278671T1 (de) 2004-10-15
AU681346B2 (en) 1997-08-28
RU2127732C1 (ru) 1999-03-20
CN1086811A (zh) 1994-05-18
SK158594A3 (en) 1995-07-11
EP1120410B1 (en) 2004-10-06
CZ281975B6 (cs) 1997-04-16
US5658910A (en) 1997-08-19
ES2169044T3 (es) 2002-07-01
CN1085981C (zh) 2002-06-05

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