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KR940019865A - 발효법에 의한 l-글루탐산의 제조법 - Google Patents

발효법에 의한 l-글루탐산의 제조법 Download PDF

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Publication number
KR940019865A
KR940019865A KR1019930016391A KR930016391A KR940019865A KR 940019865 A KR940019865 A KR 940019865A KR 1019930016391 A KR1019930016391 A KR 1019930016391A KR 930016391 A KR930016391 A KR 930016391A KR 940019865 A KR940019865 A KR 940019865A
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KR
South Korea
Prior art keywords
glutamic acid
producing
fermentation
biotin
brevibacterium
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KR1019930016391A
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English (en)
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KR100198039B1 (ko
Inventor
히데쓰구 나카자와
히로키 가와시마
이나오 오야마
게이지 이시이
요시오 가와하라
Original Assignee
도바 다다스
아지노모토 가부시키가이샤
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Publication of KR940019865A publication Critical patent/KR940019865A/ko
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Publication of KR100198039B1 publication Critical patent/KR100198039B1/ko

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/14—Glutamic acid; Glutamine
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/8215—Microorganisms
    • Y10S435/822—Microorganisms using bacteria or actinomycetales
    • Y10S435/843—Corynebacterium

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

본 발명은 야생형 균주 브레비박테리움(Brevibacterium) 속 또는 코리네박테리움(Corynebacterium) 속과 비교하여 더 낮은 α-케토글루타르산 데하이드로게나제 활성을 갖는, 상기 브레비박테리움 속 또는 코리네박테리움 속으로부터 유도된 L-글루탐산 생성 미생물의 돌연변이체를 바이오틴 활성 억제 물질을 첨가하지 않은, 농도가 10 내지 100μg/1인 바이오틴-함유 액체 영양 배지중에서 배양시키고, 배양액중에 L-글루탐산을 생성 및 축적시키고 상기 배양액으로부터 L-글루탐산을 회수함을 특징으로 하는 발효법에 의해 L-글루탐산을 제조하는 방법을 제공하는 것이다.
본 발명에 따라, 더 경제적이고 더 효율적인 방식으로 발효법에 의해 L-글루탐산을 산업적으로 제조할 수 있다.

Description

발표법에 의한 L-글루탐산의 제조법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (1)

  1. 야생형 균주 브레비박테리움(Brevibacterium) 속 또는 코리네박테리움(Corynebacterium) 속과 비교하여 더 낮은 α-케토글루타르산 데하이드로게나제 활성을 갖는, 상기 브레비박테리움 속 또는 코리네박테리움 속으로부터 유도된 L-글루탐산 생성 미생물의 돌연변이체를 바이오틴 활성 억제 물질을 첨가하지 않은, 농도가 10 내지 100μg/1인 바이오틴-함유 액체 영양 배지중에서 배양시키고, 배양액중에 L-글루탐산을 회수함을 특징으로 하는 발효법에 의해 L-글루탐산을 제조하는 방법.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019930016391A 1993-02-16 1993-08-24 발효에 의한 l-글루탐산의 제조방법 KR100198039B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP02681193A JP3301140B2 (ja) 1993-02-16 1993-02-16 発酵法によるｌ−グルタミン酸の製造法
JP93-026811 1993-02-16

Publications (2)

Publication Number Publication Date
KR940019865A true KR940019865A (ko) 1994-09-15
KR100198039B1 KR100198039B1 (ko) 1999-06-15

Family

ID=12203677

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019930016391A KR100198039B1 (ko) 1993-02-16 1993-08-24 발효에 의한 l-글루탐산의 제조방법

Country Status (8)

Country Link
US (1) US5492818A (ko)
JP (1) JP3301140B2 (ko)
KR (1) KR100198039B1 (ko)
CN (1) CN1049689C (ko)
BR (1) BR9400574A (ko)
FR (1) FR2701489B1 (ko)
MY (1) MY111441A (ko)
PH (1) PH31685A (ko)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100513996B1 (ko) * 1996-11-21 2005-12-07 아지노모토 가부시키가이샤 연속발효에의한l-글루탐산의제조방법
JP3812019B2 (ja) * 1996-11-21 2006-08-23 味の素株式会社 連続発酵によるｌ−グルタミン酸の製造法
JP2001072701A (ja) * 1999-06-29 2001-03-21 Ajinomoto Co Inc タピオカ澱粉の製造方法及びアミノ酸の発酵生産方法
US7205132B2 (en) * 2004-09-10 2007-04-17 Ajinomoto Co., Inc. L-glutamic acid-producing microorganism and a method for producing L-glutamic acid
JP4595506B2 (ja) * 2004-11-25 2010-12-08 味の素株式会社 Ｌ−アミノ酸生産菌及びｌ−アミノ酸の製造方法
US7794989B2 (en) * 2004-12-28 2010-09-14 Ajinomoto Co., Inc. L-glutamic acid-producing microorganism and a method for producing L-glutamic acid
CN101090911B (zh) 2004-12-28 2014-05-07 味之素株式会社 产生l-谷氨酸的微生物和产生l-谷氨酸的方法
JP5343303B2 (ja) * 2004-12-28 2013-11-13 味の素株式会社 Ｌ−グルタミン酸生産菌及びｌ−グルタミン酸の製造方法
JP2010041920A (ja) * 2006-12-19 2010-02-25 Ajinomoto Co Inc Ｌ−アミノ酸の製造法
JP2010130899A (ja) 2007-03-14 2010-06-17 Ajinomoto Co Inc Ｌ−グルタミン酸系アミノ酸生産微生物及びアミノ酸の製造法
RU2007147436A (ru) * 2007-12-21 2009-06-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) (RU) Бактерия-продуцент (2s,3r,4s)-4-гидрокси-l-изолейцина и способ продукции (2s,3r,4s)-4-гидрокси-l-изолейцина
RU2496867C2 (ru) 2011-04-25 2013-10-27 Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО "АГРИ") Способ получения l-аминокислоты семейства глутамата с использованием коринеформной бактерии
JP2016192903A (ja) 2013-09-17 2016-11-17 味の素株式会社 海藻由来バイオマスからのｌ−アミノ酸の製造方法
CN106459857B (zh) 2013-10-02 2019-04-19 味之素株式会社 氨控制装置及氨控制方法
CN104629768B (zh) * 2015-01-22 2017-12-15 河海大学 一种降低滩涂盐碱地土壤碱性的微生物制品
CN105274181A (zh) * 2015-10-28 2016-01-27 新疆阜丰生物科技有限公司 一种从发酵液中提取γ-聚谷氨酸的方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5224593B2 (ko) * 1973-10-17 1977-07-01
JPS561889A (en) * 1979-06-20 1981-01-10 Ajinomoto Co Inc Preparation of l-glutamic acid by fermentation
US4411991A (en) * 1980-10-07 1983-10-25 Kanegafuchi Chemical Industry Company, Limited Process for fermentative production of amino acids
JPS57115190A (en) * 1980-12-29 1982-07-17 Ajinomoto Co Inc Preparation of l-glutamic acid by fermentation
JPS58158192A (ja) * 1982-03-15 1983-09-20 Ajinomoto Co Inc 発酵法によるｌ−グルタミン酸の製造方法
US5234994A (en) * 1988-11-01 1993-08-10 Asani Kasei Kogyo Kabushiki Kaisha Thermoplastic polymer composition
EP0469517A3 (en) * 1990-07-30 1992-10-28 Kyowa Hakko Kogyo Co., Ltd. Process for producing l-glutamic acid

Also Published As

Publication number Publication date
CN1049689C (zh) 2000-02-23
JP3301140B2 (ja) 2002-07-15
FR2701489A1 (fr) 1994-08-19
MY111441A (en) 2000-05-31
PH31685A (en) 1999-01-18
BR9400574A (pt) 1994-08-23
US5492818A (en) 1996-02-20
KR100198039B1 (ko) 1999-06-15
JPH06237779A (ja) 1994-08-30
FR2701489B1 (fr) 1996-11-15
CN1092467A (zh) 1994-09-21

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