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KR880004087A - 아미노산의 제조방법 - Google Patents

아미노산의 제조방법 Download PDF

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Publication number
KR880004087A
KR880004087A KR870010053A KR870010053A KR880004087A KR 880004087 A KR880004087 A KR 880004087A KR 870010053 A KR870010053 A KR 870010053A KR 870010053 A KR870010053 A KR 870010053A KR 880004087 A KR880004087 A KR 880004087A
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acetyl
arginino
synthesis
genetic information
phosphate reductase
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KR900004424B1 (ko
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료이찌 가쓰마따
하루히꼬 요꼬이
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가또 미끼오
교오와학꼬고오교 가부시끼가이샤
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/10—Citrulline; Arginine; Ornithine

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  • Organic Chemistry (AREA)
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  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
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Abstract

내용 없음

Description

아미노산의 제조방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음
제1도는 pEarg2, pEarg3 및 pEarg4의 제한 효소 BamHI, BanⅢ, PstⅠ 및 SalI 절단 지도 및 그의 형성 단계를 나타낸 것이다.

Claims (7)

  1. 에스케리키아 속에 속하는 미생물의 N-아세틸 글루타메이트 키나아제, N-아세틸-γ-글루타밀 포스페이트 리덕타제, 아르기니노 숙시나제 및 아르기니노 숙시네이트 합성 효소의 군에서 선택된 적어도 3효소의 합성에 관한 유전 정보를 갖는 재조합 DNA를 운반하는 코리네박테리움 또는 브레비박테리움 속에 속하는 미생물을 회수 가능한 량의 아미노산이 배양브로스에 축적될 때까지 배지에서 배양하고, 그로부터 아미노산을 회수함을 특징으로 하는 L-아르기닌, L-시트룰린 및 L-오르니틴의 군에서 선택된 아미노산의 제조방법.
  2. 제1항에 있어서, 유전정보가 N-아세틸 글루타메이트 키나아제, N-아세틸-γ-글루타밀 포스페이트 리덕타제, 및 아르기니노 숙시나제의 합성에 관한 것이고, 아미노산이 L-아르기닌, L-시트룰린 및 L-오르니틴인 방법.
  3. 제1항에 있어서, 유전정보가 N-아세틸 글루타메이트 키나아제, N-아세틸-γ-글루타밀 포스페이트 리덕타제, 아르기니노 숙시나제 및 아르기니노 숙시네이트 합성효소의 합성에 관한 것이고, 아미노산이 L-아르기닌인 방법.
  4. 에스케리키아 속에 속하는 미생물의 N-아세틸 글루타메이트 키나아제, N-아세틸-γ-글루타밀 포스페이트 리덕타제, 및 아르기니노 숙시나제의 합성에 관한 유전정보를 갖는 재조합 DNA.
  5. 에스케리키아 속에 속하는 미생물의 N-아세틸 글루타메이트 키나아제, N-아세틸-γ-글루타밀 포스페이트 리덕타제, 아르기니노 숙시나제 및 아르기니노 숙시네이트의 합성 효소의 합성에 관한 유전정보를 갖는 재조합 DNA.
  6. 에스케리키아 속에 속하는 미생물의 N-아세틸 글루타메이트 키나아제, N-아세틸-γ-글루타밀 포스페이트 리덕타제, 및 아르기니노 숙시나제의 합성에 관한 유전정보를 갖는 재조합 DNA를 운반하는 코리네박테리움 또는 브레비박테리움 속에 속하는 미생물.
  7. 에스케리키아 속에 속하는 미생물의 N-아세틸 글루타메이트 키나아제, N-아세틸-γ-글루타밀 포스페이트 리덕타제, 아르기니노 숙시나제 및 아르기니노 숙시네이트의 합성 효소의 합성에 관한 유전정보를 갖는 재조합 DNA를 운반하는 코리네 박테리움 또는 브레비박테리움 속에 속하는 미생물.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019870010053A 1986-09-10 1987-09-10 아미노산의 제조방법 Expired KR900004424B1 (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP61213572A JPH0755155B2 (ja) 1986-09-10 1986-09-10 アミノ酸の製造法
JP213572 1988-09-10

Publications (2)

Publication Number Publication Date
KR880004087A true KR880004087A (ko) 1988-06-01
KR900004424B1 KR900004424B1 (ko) 1990-06-25

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Application Number Title Priority Date Filing Date
KR1019870010053A Expired KR900004424B1 (ko) 1986-09-10 1987-09-10 아미노산의 제조방법

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EP (1) EP0259858B1 (ko)
JP (1) JPH0755155B2 (ko)
KR (1) KR900004424B1 (ko)
DE (1) DE3785119T2 (ko)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3078312B2 (ja) * 1990-11-22 2000-08-21 協和醗酵工業株式会社 物質の製造法
JP2000197490A (ja) * 1998-11-02 2000-07-18 Ajinomoto Co Inc Ｌ―アルギニンの製造法
MXPA01010413A (es) 1999-04-19 2002-11-29 Kyowa Hakko Kogyo Kk Aspartoquinasa desensibilizada novedosa.
US7160705B2 (en) 2000-04-28 2007-01-09 Ajinomoto Co., Inc. Arginine repressor deficient strain of coryneform bacterium and method for producing L-arginine
WO2006035831A1 (ja) * 2004-09-28 2006-04-06 Kyowa Hakko Kogyo Co., Ltd. Ｌ－アルギニン、ｌ－オルニチンまたはｌ－シトルリンの製造法
CN103561764B (zh) 2011-03-11 2015-09-16 一般财团法人化学及血清疗法研究所 含有瓜氨酸的佐剂组合物
ES2761224T3 (es) 2012-02-15 2020-05-19 Kyowa Hakko Bio Co Ltd Agente para prevenir o mejorar la disfunción vascular endotelial
KR101735935B1 (ko) 2015-07-20 2017-05-16 씨제이제일제당 (주) 퓨트레신 또는 오르니틴 생산 미생물 및 이를 이용한 퓨트레신 또는 오르니틴 생산방법

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS575693A (en) * 1980-06-13 1982-01-12 Ajinomoto Co Inc Production of l-arginine through fermentation process
JPS5867699A (ja) * 1981-10-16 1983-04-22 Ajinomoto Co Inc プラスミド
JPS6066989A (ja) * 1983-09-24 1985-04-17 Kyowa Hakko Kogyo Co Ltd Ｌ−アルギニンの製造法
WO1984003301A1 (en) * 1983-02-17 1984-08-30 Kyowa Hakko Kogyo Kk Process for preparing amino acid

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Publication number Publication date
DE3785119T2 (de) 1993-07-08
KR900004424B1 (ko) 1990-06-25
JPH0755155B2 (ja) 1995-06-14
EP0259858A3 (en) 1989-10-11
DE3785119D1 (de) 1993-05-06
EP0259858B1 (en) 1993-03-31
EP0259858A2 (en) 1988-03-16
JPS6368091A (ja) 1988-03-26

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