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KR930016536A - L-리신을 분비하는 코리네형 세균의 효율 증진 방법 - Google Patents

L-리신을 분비하는 코리네형 세균의 효율 증진 방법 Download PDF

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Publication number
KR930016536A
KR930016536A KR1019930000468A KR930000468A KR930016536A KR 930016536 A KR930016536 A KR 930016536A KR 1019930000468 A KR1019930000468 A KR 1019930000468A KR 930000468 A KR930000468 A KR 930000468A KR 930016536 A KR930016536 A KR 930016536A
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South Korea
Prior art keywords
lysine
strain
efficiency
coryneform
secrete
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KR1019930000468A
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English (en)
Inventor
키르케 만프레트
바크만 베른트
Original Assignee
볼프강 베버, 마르틴 펠드만
데구사 아크티엔게젤샤프트
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Application filed by 볼프강 베버, 마르틴 펠드만, 데구사 아크티엔게젤샤프트 filed Critical 볼프강 베버, 마르틴 펠드만
Publication of KR930016536A publication Critical patent/KR930016536A/ko

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/08—Lysine; Diaminopimelic acid; Threonine; Valine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/13—Brevibacterium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/15—Corynebacterium
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y203/00—Acyltransferases (2.3)
    • C12Y203/03—Acyl groups converted into alkyl on transfer (2.3.3)
    • C12Y203/03001—Citrate (Si)-synthase (2.3.3.1)

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Biomedical Technology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

본 발명은 L-아스파라긴산β-메틸에스테르에 대한 내성이 유발되고 몇몇 경우에는 모 균주와 비교하여 감소된 시트레이트-신타제 활성을 나타내는, L-리신을 분비하는 코리네형 균주의 효율을 증진시키는 방법에 관한 것이다.

Description

L-리신을 분비하는 코리네형 세균의 효율 증진 방법
본 내용은 요부공개 건이므로 전문내용을 수록하지 않았음

Claims (6)

  1. L-리신을 분비하는 코리네형(coryneform)균주에서 L-아스파라긴산 β-메틸에스테르에 대한 내성을 유발시킴을 특징으로 하여, L-리신을 분비하는 미생물중 코리네형 균주의 효율을 증가시키는 방법.
  2. 제1항에 있어서, L-리신을 분비하는 코리네형 균주로부터 유래하는 돌연변이체가 모(panent)균주보다 낮은 시트레이트 신타제 활성을 갖는 방법.
  3. 제1항 또는 제2항에 있어서, 코리네박테리움(Corynebacterium)또는 브레비박테리움(Brevibacterium)속의 균주가 사용되는 방법.
  4. L-아스파라긴산 β-메틸에스테르에 대한 내성을 나타내고, 제1항에 따라 생성된, L-리신을 분비하는 코리네박테리움 또는 브레비박테리움속의 균주.
  5. L-리신을 분비하고, 추기로 모 균주보다 낮은 시트레이트-신타제 활성을 가지며, 제2항에 따라 생성된 균주.
  6. L-리신을 발효 생성하기 위한 제4항 또는 제5항에 따른 L- 리신 분비 균주의 용도.
    ※ 참고사항 : 최초출원 내용에 의하여 공개하는 것임.
KR1019930000468A 1992-01-17 1993-01-15 L-리신을 분비하는 코리네형 세균의 효율 증진 방법 KR930016536A (ko)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DEP4201085.30 1992-01-17
DE4201085A DE4201085A1 (de) 1992-01-17 1992-01-17 Verfahren zur erhoehung der leistungsfaehigkeit l-lysin ausscheidender coryneformer bakterien

Publications (1)

Publication Number Publication Date
KR930016536A true KR930016536A (ko) 1993-08-26

Family

ID=6449682

Family Applications (1)

Application Number Title Priority Date Filing Date
KR1019930000468A KR930016536A (ko) 1992-01-17 1993-01-15 L-리신을 분비하는 코리네형 세균의 효율 증진 방법

Country Status (9)

Country Link
EP (1) EP0551614B1 (ko)
JP (1) JPH06197779A (ko)
KR (1) KR930016536A (ko)
AU (1) AU670767B2 (ko)
BR (1) BR9300119A (ko)
DE (2) DE4201085A1 (ko)
HU (1) HU216326B (ko)
SK (1) SK280158B6 (ko)
TW (1) TW211038B (ko)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022050527A1 (ko) * 2020-09-03 2022-03-10 대상 주식회사 L-라이신 생산능이 향상된 코리네박테리움 글루타미쿰 변이주 및 이를 이용한 l-라이신의 생산 방법

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2305577A1 (en) 1997-10-04 1999-04-15 Forschungszentrum Julich Gmbh Method for microbial production of amino acids of the aspartate and/or glutamate family and agents which can be used in said method
AU2001295456A1 (en) * 2000-09-12 2002-03-26 Degussa A.G. Nucleotide sequences which code for the gora gene
DE102006032634A1 (de) 2006-07-13 2008-01-17 Evonik Degussa Gmbh Verfahren zur Herstellung von L-Aminosäuren

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS539394A (en) * 1976-07-09 1978-01-27 Kyowa Hakko Kogyo Co Ltd Preparation of l-lysine by fermentation

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2022050527A1 (ko) * 2020-09-03 2022-03-10 대상 주식회사 L-라이신 생산능이 향상된 코리네박테리움 글루타미쿰 변이주 및 이를 이용한 l-라이신의 생산 방법

Also Published As

Publication number Publication date
TW211038B (en) 1993-08-11
HUT64398A (en) 1993-12-28
DE4201085A1 (de) 1993-07-22
HU9300104D0 (en) 1993-04-28
BR9300119A (pt) 1993-08-24
JPH06197779A (ja) 1994-07-19
EP0551614A3 (en) 1994-08-17
EP0551614A2 (de) 1993-07-21
SK392792A3 (en) 1996-01-10
SK280158B6 (sk) 1999-09-10
AU670767B2 (en) 1996-08-01
EP0551614B1 (de) 1996-04-10
DE59205963D1 (de) 1996-05-15
HU216326B (hu) 1999-06-28
AU3181993A (en) 1993-07-22

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PA0109 Patent application

Patent event code: PA01091R01D

Comment text: Patent Application

Patent event date: 19930115

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