KR20060052912A - 항콜린제와 스테로이드의 배합물 및 흡입으로 호흡기장애를 치료하기 위한 이의 용도 - Google Patents

항콜린제와 스테로이드의 배합물 및 흡입으로 호흡기장애를 치료하기 위한 이의 용도 Download PDF

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Publication number: KR20060052912A
Authority: KR; South Korea
Prior art keywords: inhalation; pharmaceutical composition; propellant; oxo; formula
Prior art date: 2003-07-29
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Ceased

Application number

KR1020067001862A

Other languages

English (en)

Korean (ko)

Inventor

크리스토퍼 존 몬테규 미드

미첼 뻬레뜨

미카엘 페 피퍼

Original Assignee

베링거 인겔하임 인터내셔날 게엠베하

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2003-07-29

Filing date

2004-07-17

Publication date

2006-05-19

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=34130038&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=KR20060052912(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2004-07-17 Application filed by 베링거 인겔하임 인터내셔날 게엠베하 filed Critical 베링거 인겔하임 인터내셔날 게엠베하

2006-05-19 Publication of KR20060052912A publication Critical patent/KR20060052912A/ko

Status Ceased legal-status Critical Current

Links

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239000008194 pharmaceutical composition Substances 0.000 claims abstract description 28
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238000000034 method Methods 0.000 claims abstract description 13
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239000000203 mixture Substances 0.000 claims description 46
239000000443 aerosol Substances 0.000 claims description 33
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XBDQKXXYIPTUBI-UHFFFAOYSA-M Propionate Chemical compound CCC([O-])=O XBDQKXXYIPTUBI-UHFFFAOYSA-M 0.000 claims description 4
NBMKJKDGKREAPL-DVTGEIKXSA-N beclomethasone Chemical compound C1CC2=CC(=O)C=C[C@]2(C)[C@]2(Cl)[C@@H]1[C@@H]1C[C@H](C)[C@@](C(=O)CO)(O)[C@@]1(C)C[C@@H]2O NBMKJKDGKREAPL-DVTGEIKXSA-N 0.000 claims description 4
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150000002148 esters Chemical class 0.000 claims description 4
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Images

Classifications

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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4738—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems
- A61K31/4745—Quinolines; Isoquinolines ortho- or peri-condensed with heterocyclic ring systems condensed with ring systems having nitrogen as a ring hetero atom, e.g. phenantrolines
- A—HUMAN NECESSITIES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A—HUMAN NECESSITIES
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- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
- A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
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- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
- A—HUMAN NECESSITIES
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- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P11/06—Antiasthmatics
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings

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Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
General Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Animal Behavior & Ethology (AREA)
Medicinal Chemistry (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Pharmacology & Pharmacy (AREA)
Epidemiology (AREA)
Organic Chemistry (AREA)
Engineering & Computer Science (AREA)
Bioinformatics & Cheminformatics (AREA)
Pulmonology (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Chemical Kinetics & Catalysis (AREA)
Otolaryngology (AREA)
Rheumatology (AREA)
Pain & Pain Management (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Medicinal Preparation (AREA)
Nitrogen Condensed Heterocyclic Rings (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

KR1020067001862A 2003-07-29 2004-07-17 항콜린제와 스테로이드의 배합물 및 흡입으로 호흡기장애를 치료하기 위한 이의 용도 Ceased KR20060052912A (ko)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
EP03017162.3		2003-07-29
EP03017162		2003-07-29

Publications (1)

Publication Number	Publication Date
KR20060052912A true KR20060052912A (ko)	2006-05-19

Family

ID=34130038

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
KR1020067001862A Ceased KR20060052912A (ko)	2003-07-29	2004-07-17	항콜린제와 스테로이드의 배합물 및 흡입으로 호흡기장애를 치료하기 위한 이의 용도

Country Status (12)

Country	Link
EP (1)	EP1651236A1 (zh)
JP (1)	JP2007500150A (zh)
KR (1)	KR20060052912A (zh)
CN (1)	CN1829520A (zh)
AU (1)	AU2004262901B2 (zh)
BR (1)	BRPI0413054A (zh)
CA (1)	CA2534128C (zh)
IL (1)	IL173370A0 (zh)
MX (1)	MXPA06001046A (zh)
NZ (1)	NZ545443A (zh)
RU (1)	RU2361586C2 (zh)
WO (1)	WO2005014005A1 (zh)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2165768B1 (es)	1999-07-14	2003-04-01	Almirall Prodesfarma Sa	Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
ES2298049B1 (es)	2006-07-21	2009-10-20	Laboratorios Almirall S.A.	Procedimiento para fabricar bromuro de 3(r)-(2-hidroxi-2,2-ditien-2-ilacetoxi)-1-(3-fenoxipropil)-1-azoniabiciclo (2.2.2) octano.
EP2100598A1 (en)	2008-03-13	2009-09-16	Laboratorios Almirall, S.A.	Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
EP2100599A1 (en) *	2008-03-13	2009-09-16	Laboratorios Almirall, S.A.	Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease
US8815258B2 (en)	2009-05-29	2014-08-26	Pearl Therapeutics, Inc.	Compositions, methods and systems for respiratory delivery of two or more active agents
PL2435025T3 (pl)	2009-05-29	2017-08-31	Pearl Therapeutics, Inc.	Dostarczanie substancji czynnych do dróg oddechowych
EP2510928A1 (en)	2011-04-15	2012-10-17	Almirall, S.A.	Aclidinium for use in improving the quality of sleep in respiratory patients
EP2968152B2 (en)	2013-03-15	2022-06-22	Pearl Therapeutics, Inc.	Methods and systems for conditioning of particulate crystalline materials

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
ES2165768B1 (es) *	1999-07-14	2003-04-01	Almirall Prodesfarma Sa	Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen.
US20020183292A1 (en) *	2000-10-31	2002-12-05	Michel Pairet	Pharmaceutical compositions based on anticholinergics and corticosteroids
ES2257152B1 (es) *	2004-05-31	2007-07-01	Laboratorios Almirall S.A.	Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos.

2004
- 2004-07-17 CN CNA2004800220913A patent/CN1829520A/zh active Pending
- 2004-07-17 MX MXPA06001046A patent/MXPA06001046A/es unknown
- 2004-07-17 WO PCT/EP2004/008029 patent/WO2005014005A1/en active Application Filing
- 2004-07-17 KR KR1020067001862A patent/KR20060052912A/ko not_active Ceased
- 2004-07-17 CA CA2534128A patent/CA2534128C/en not_active Expired - Lifetime
- 2004-07-17 EP EP04763322A patent/EP1651236A1/en not_active Withdrawn
- 2004-07-17 RU RU2006105719/15A patent/RU2361586C2/ru not_active IP Right Cessation
- 2004-07-17 BR BRPI0413054-5A patent/BRPI0413054A/pt not_active IP Right Cessation
- 2004-07-17 AU AU2004262901A patent/AU2004262901B2/en not_active Revoked
- 2004-07-17 NZ NZ545443A patent/NZ545443A/en not_active IP Right Cessation
- 2004-07-17 JP JP2006521460A patent/JP2007500150A/ja active Pending
2006
- 2006-01-26 IL IL173370A patent/IL173370A0/en unknown

Also Published As

Publication number	Publication date
CA2534128C (en)	2012-10-23
CN1829520A (zh)	2006-09-06
IL173370A0 (en)	2006-06-11
AU2004262901A1 (en)	2005-02-17
EP1651236A1 (en)	2006-05-03
NZ545443A (en)	2010-04-30
WO2005014005A1 (en)	2005-02-17
RU2006105719A (ru)	2007-12-10
CA2534128A1 (en)	2005-02-17
BRPI0413054A (pt)	2006-10-17
JP2007500150A (ja)	2007-01-11
RU2361586C2 (ru)	2009-07-20
AU2004262901B2 (en)	2010-05-13
MXPA06001046A (es)	2006-04-24

Publication	Publication Date	Title
JP4537652B2 (ja)	2010-09-01	抗コリン作用薬及びシクレソニドをベースとする新規薬剤組成物
JP4282594B2 (ja)	2009-06-24	チオトロピウム塩及びサルメテロール塩に基づく新規医薬組成物
CA2733294C (en)	2011-12-20	Pharmaceutical combination of a tiotropium salt and ciclesonide
US20040176338A1 (en)	2004-09-09	Pharmaceutical compositions based on anticholinergics and corticosteroids
US20110038806A1 (en)	2011-02-17	Medicaments for inhalation comprising an anticholinergic and a steroid
US7084153B2 (en)	2006-08-01	Medicaments comprising steroids and a novel anticholinergic
US20020189610A1 (en)	2002-12-19	Pharmaceutical compositions containing an ipratropium salt and a betamimetic
JP2004517942A (ja)	2004-06-17	ほとんど副作用を伴わないβ様物質を含む医薬組成物
AU2003298473B2 (en)	2009-04-23	Aerosol formulation for inhalation containing an anticholinergic agent
IL174496A (en)	2010-05-31	Aerosol formulation for inhalation containing an anticholinergic agent
PL213489B1 (pl)	2013-03-29	Kompozycje farmaceutyczne zawierajace betamimetyk i nowy lek antycholinergiczny oraz zastosowanie kompozycji
PL212070B1 (pl)	2012-08-31	Kompozycje farmaceutyczne do inhalacji zawierające lek antycholinergiczny i kortykosteroid i ich zastosowanie
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