JPS5513253A - Cis-3-aralkyl substituted-8-benzoylthio-6,11-dimethyl-2,6- methano-1,2,3,4,5,6-hexahydro-3-benzazocine or its acid addition salt - Google Patents
Cis-3-aralkyl substituted-8-benzoylthio-6,11-dimethyl-2,6- methano-1,2,3,4,5,6-hexahydro-3-benzazocine or its acid addition saltInfo
- Publication number
- JPS5513253A JPS5513253A JP8666178A JP8666178A JPS5513253A JP S5513253 A JPS5513253 A JP S5513253A JP 8666178 A JP8666178 A JP 8666178A JP 8666178 A JP8666178 A JP 8666178A JP S5513253 A JPS5513253 A JP S5513253A
- Authority
- JP
- Japan
- Prior art keywords
- benzazocine
- methano
- hexahydro
- cis
- dimethyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000002253 acid Substances 0.000 title 1
- 150000003839 salts Chemical class 0.000 title 1
- -1 2-(2-thienyl) ethyl Chemical group 0.000 abstract 3
- 150000001875 compounds Chemical class 0.000 abstract 2
- 125000000094 2-phenylethyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])C([H])([H])* 0.000 abstract 1
- 229940035676 analgesics Drugs 0.000 abstract 1
- 239000000730 antalgic agent Substances 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 239000012280 lithium aluminium hydride Substances 0.000 abstract 1
- 239000000463 material Substances 0.000 abstract 1
- LMBFAGIMSUYTBN-MPZNNTNKSA-N teixobactin Chemical compound C([C@H](C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H](CCC(N)=O)C(=O)N[C@H]([C@@H](C)CC)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@@H](CO)C(=O)N[C@H]1C(N[C@@H](C)C(=O)N[C@@H](C[C@@H]2NC(=N)NC2)C(=O)N[C@H](C(=O)O[C@H]1C)[C@@H](C)CC)=O)NC)C1=CC=CC=C1 LMBFAGIMSUYTBN-MPZNNTNKSA-N 0.000 abstract 1
Landscapes
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
NEW MATERIAL:The title compound of formula I [R is phenethyl, 2-(2-thienyl) ethyl, or benzyl group].
USE: Analgesics.
PROCESS: A cis-3-aralkyl substituted-8-(dimethylcarbamoylthio)-6,11-dimethyl-2,6- methano-1,2,3,4,5,6-hexahydro-3-benzazocine of formula II is reacted with lithium aluminum hydride and then a benzoyl halide to give the objective compound. The novel compound of formula II can be prepared according to the reaction formula.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8666178A JPS5513253A (en) | 1978-07-15 | 1978-07-15 | Cis-3-aralkyl substituted-8-benzoylthio-6,11-dimethyl-2,6- methano-1,2,3,4,5,6-hexahydro-3-benzazocine or its acid addition salt |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP8666178A JPS5513253A (en) | 1978-07-15 | 1978-07-15 | Cis-3-aralkyl substituted-8-benzoylthio-6,11-dimethyl-2,6- methano-1,2,3,4,5,6-hexahydro-3-benzazocine or its acid addition salt |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS5513253A true JPS5513253A (en) | 1980-01-30 |
Family
ID=13893207
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP8666178A Pending JPS5513253A (en) | 1978-07-15 | 1978-07-15 | Cis-3-aralkyl substituted-8-benzoylthio-6,11-dimethyl-2,6- methano-1,2,3,4,5,6-hexahydro-3-benzazocine or its acid addition salt |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5513253A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002537393A (en) * | 1999-02-23 | 2002-11-05 | ベーリンガー インゲルハイム ファルマ コマンディトゲゼルシャフト | Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzoazosin-10-ols, processes for their preparation and their use as drugs |
-
1978
- 1978-07-15 JP JP8666178A patent/JPS5513253A/en active Pending
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2002537393A (en) * | 1999-02-23 | 2002-11-05 | ベーリンガー インゲルハイム ファルマ コマンディトゲゼルシャフト | Substituted 1,2,3,4,5,6-hexahydro-2,6-methano-3-benzoazosin-10-ols, processes for their preparation and their use as drugs |
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