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JPS5479247A - Para-substituted phenylacetic acid derivative and its preparation - Google Patents

Para-substituted phenylacetic acid derivative and its preparation

Info

Publication number
JPS5479247A
JPS5479247A JP14660677A JP14660677A JPS5479247A JP S5479247 A JPS5479247 A JP S5479247A JP 14660677 A JP14660677 A JP 14660677A JP 14660677 A JP14660677 A JP 14660677A JP S5479247 A JPS5479247 A JP S5479247A
Authority
JP
Japan
Prior art keywords
phenylacetic acid
para
preparation
formula
lower alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP14660677A
Other languages
Japanese (ja)
Other versions
JPS5542984B2 (en
Inventor
Toshio Tanaka
Toshio Wakabayashi
Hitoshi Omori
Seiji Kurozumi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Priority to JP14660677A priority Critical patent/JPS5479247A/en
Publication of JPS5479247A publication Critical patent/JPS5479247A/en
Publication of JPS5542984B2 publication Critical patent/JPS5542984B2/ja
Granted legal-status Critical Current

Links

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  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

NEW MATERIAL:Para-substituted phenylacetic acid derivatives of formulaI(R1 is lower alkyl; R2 is H, lower alkyl; R3 is H, lower alkyl, inorganic or organic cation; n is 0W2).
EXAMPLE: p-Methylthiomethylphenylacetic acid.
USE: Antiflammatory agents and antithrombotic agents.
PREPARATION: The reaction of p-chloromethylphenylacetic acid of formula II (R31 is R3) with an alkylthiol of formula: R1SH (R1 is preferably 1W10C alkyl) is effected in an alkaline medium, then the reaction product is subjected to hydrolysis, cation exchange, and oxidation to yield the compound of formulaI. The compound of formula II is prepared by chloromethylation of phenylacetic acid or its ester.
COPYRIGHT: (C)1979,JPO&Japio
JP14660677A 1977-12-08 1977-12-08 Para-substituted phenylacetic acid derivative and its preparation Granted JPS5479247A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP14660677A JPS5479247A (en) 1977-12-08 1977-12-08 Para-substituted phenylacetic acid derivative and its preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP14660677A JPS5479247A (en) 1977-12-08 1977-12-08 Para-substituted phenylacetic acid derivative and its preparation

Publications (2)

Publication Number Publication Date
JPS5479247A true JPS5479247A (en) 1979-06-25
JPS5542984B2 JPS5542984B2 (en) 1980-11-04

Family

ID=15411523

Family Applications (1)

Application Number Title Priority Date Filing Date
JP14660677A Granted JPS5479247A (en) 1977-12-08 1977-12-08 Para-substituted phenylacetic acid derivative and its preparation

Country Status (1)

Country Link
JP (1) JPS5479247A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002020366A (en) * 2000-07-05 2002-01-23 Sumitomo Seika Chem Co Ltd Method for producing alkylthiophenylacetic acid

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002020366A (en) * 2000-07-05 2002-01-23 Sumitomo Seika Chem Co Ltd Method for producing alkylthiophenylacetic acid

Also Published As

Publication number Publication date
JPS5542984B2 (en) 1980-11-04

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