JPH0517831B2 - - Google Patents

Info

Publication number: JPH0517831B2
Authority: JP; Japan
Prior art keywords: amylase; streptomyces; culture; amylase inhibitor; aiu
Prior art date: 1988-08-09
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

JP1171752A

Other languages

English (en)

Japanese (ja)

Other versions

JPH02131571A (ja

Inventor

Kyun Rii Iyoo

Uon Paku Iyoo

Uon Choi Shin

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

YON JIN PHARM IND CO Ltd

Original Assignee

YON JIN PHARM IND CO Ltd

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1988-08-09

Filing date

1989-07-03

Publication date

1993-03-10

1989-07-03 Application filed by YON JIN PHARM IND CO Ltd filed Critical YON JIN PHARM IND CO Ltd

1990-05-21 Publication of JPH02131571A publication Critical patent/JPH02131571A/ja

1993-03-10 Publication of JPH0517831B2 publication Critical patent/JPH0517831B2/ja

Status Granted legal-status Critical Current

Links

239000003392 amylase inhibitor Substances 0.000 claims description 51
229940122816 Amylase inhibitor Drugs 0.000 claims description 38
241000187180 Streptomyces sp. Species 0.000 claims description 19
229920001817 Agar Polymers 0.000 claims description 17
239000008272 agar Substances 0.000 claims description 17
229910052799 carbon Inorganic materials 0.000 claims description 7
OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 6
WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 claims description 6
238000004519 manufacturing process Methods 0.000 claims description 4
240000004808 Saccharomyces cerevisiae Species 0.000 claims description 3
GXCLVBGFBYZDAG-UHFFFAOYSA-N N-[2-(1H-indol-3-yl)ethyl]-N-methylprop-2-en-1-amine Chemical compound CN(CCC1=CNC2=C1C=CC=C2)CC=C GXCLVBGFBYZDAG-UHFFFAOYSA-N 0.000 claims description 2
235000020262 oat milk Nutrition 0.000 claims 1
239000000243 solution Substances 0.000 description 37
LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 27
102000013142 Amylases Human genes 0.000 description 20
108010065511 Amylases Proteins 0.000 description 20
235000019418 amylase Nutrition 0.000 description 20
238000000034 method Methods 0.000 description 20
239000012141 concentrate Substances 0.000 description 19
239000004382 Amylase Substances 0.000 description 18
239000002609 medium Substances 0.000 description 18
FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 16
239000002244 precipitate Substances 0.000 description 16
230000001580 bacterial effect Effects 0.000 description 15
229920002472 Starch Polymers 0.000 description 14
244000005700 microbiome Species 0.000 description 14
235000019698 starch Nutrition 0.000 description 14
239000008107 starch Substances 0.000 description 14
XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 14
230000000694 effects Effects 0.000 description 13
OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 12
239000012153 distilled water Substances 0.000 description 12
239000003112 inhibitor Substances 0.000 description 11
230000002401 inhibitory effect Effects 0.000 description 11
239000000126 substance Substances 0.000 description 10
241000699670 Mus sp. Species 0.000 description 9
241000187747 Streptomyces Species 0.000 description 9
235000000346 sugar Nutrition 0.000 description 9
239000011780 sodium chloride Substances 0.000 description 8
239000012535 impurity Substances 0.000 description 7
IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 6
102000005744 Glycoside Hydrolases Human genes 0.000 description 6
108010031186 Glycoside Hydrolases Proteins 0.000 description 6
239000002518 antifoaming agent Substances 0.000 description 6
238000005119 centrifugation Methods 0.000 description 6
239000000706 filtrate Substances 0.000 description 6
238000002523 gelfiltration Methods 0.000 description 6
238000012360 testing method Methods 0.000 description 6
241001465754 Metazoa Species 0.000 description 5
239000008103 glucose Substances 0.000 description 5
239000001963 growth medium Substances 0.000 description 5
230000005764 inhibitory process Effects 0.000 description 5
VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 4
OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 description 4
230000037396 body weight Effects 0.000 description 4
229940041514 candida albicans extract Drugs 0.000 description 4
239000012531 culture fluid Substances 0.000 description 4
238000001914 filtration Methods 0.000 description 4
238000001179 sorption measurement Methods 0.000 description 4
OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 description 4
239000012138 yeast extract Substances 0.000 description 4
WFIYPADYPQQLNN-UHFFFAOYSA-N 2-[2-(4-bromopyrazol-1-yl)ethyl]isoindole-1,3-dione Chemical compound C1=C(Br)C=NN1CCN1C(=O)C2=CC=CC=C2C1=O WFIYPADYPQQLNN-UHFFFAOYSA-N 0.000 description 3
QKNYBSVHEMOAJP-UHFFFAOYSA-N 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydron;chloride Chemical compound Cl.OCC(N)(CO)CO QKNYBSVHEMOAJP-UHFFFAOYSA-N 0.000 description 3
CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 description 3
102000004190 Enzymes Human genes 0.000 description 3
108090000790 Enzymes Proteins 0.000 description 3
XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 description 3
241000699666 Mus <mouse, genus> Species 0.000 description 3
239000001888 Peptone Substances 0.000 description 3
108010080698 Peptones Proteins 0.000 description 3
238000002835 absorbance Methods 0.000 description 3
102000016679 alpha-Glucosidases Human genes 0.000 description 3
108010028144 alpha-Glucosidases Proteins 0.000 description 3
239000008280 blood Substances 0.000 description 3
210000004369 blood Anatomy 0.000 description 3
230000000052 comparative effect Effects 0.000 description 3
229940088598 enzyme Drugs 0.000 description 3
235000011389 fruit/vegetable juice Nutrition 0.000 description 3
229910017053 inorganic salt Inorganic materials 0.000 description 3
235000013372 meat Nutrition 0.000 description 3
239000000203 mixture Substances 0.000 description 3
230000000877 morphologic effect Effects 0.000 description 3
229910052757 nitrogen Inorganic materials 0.000 description 3
239000003960 organic solvent Substances 0.000 description 3
235000019319 peptone Nutrition 0.000 description 3
235000020183 skimmed milk Nutrition 0.000 description 3
230000001954 sterilising effect Effects 0.000 description 3
OWEGMIWEEQEYGQ-UHFFFAOYSA-N 100676-05-9 Natural products OC1C(O)C(O)C(CO)OC1OCC1C(O)C(O)C(O)C(OC2C(OC(O)C(O)C2O)CO)O1 OWEGMIWEEQEYGQ-UHFFFAOYSA-N 0.000 description 2
LWFUFLREGJMOIZ-UHFFFAOYSA-N 3,5-dinitrosalicylic acid Chemical compound OC(=O)C1=CC([N+]([O-])=O)=CC([N+]([O-])=O)=C1O LWFUFLREGJMOIZ-UHFFFAOYSA-N 0.000 description 2
241000894006 Bacteria Species 0.000 description 2
229920002261 Corn starch Polymers 0.000 description 2
208000007882 Gastritis Diseases 0.000 description 2
PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
208000031226 Hyperlipidaemia Diseases 0.000 description 2
XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 description 2
GUBGYTABKSRVRQ-PICCSMPSSA-N Maltose Natural products O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)OC(O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-PICCSMPSSA-N 0.000 description 2
208000008589 Obesity Diseases 0.000 description 2
208000007107 Stomach Ulcer Diseases 0.000 description 2
230000009471 action Effects 0.000 description 2
229940024606 amino acid Drugs 0.000 description 2
235000001014 amino acid Nutrition 0.000 description 2
150000001413 amino acids Chemical class 0.000 description 2
229940025131 amylases Drugs 0.000 description 2
150000001720 carbohydrates Chemical class 0.000 description 2
235000014633 carbohydrates Nutrition 0.000 description 2
230000035425 carbon utilization Effects 0.000 description 2
239000003795 chemical substances by application Substances 0.000 description 2
238000007796 conventional method Methods 0.000 description 2
239000008120 corn starch Substances 0.000 description 2
238000012258 culturing Methods 0.000 description 2
206010012601 diabetes mellitus Diseases 0.000 description 2
208000000718 duodenal ulcer Diseases 0.000 description 2
238000010828 elution Methods 0.000 description 2
150000004676 glycans Chemical class 0.000 description 2
239000004093 hydrolase inhibitor Substances 0.000 description 2
201000001421 hyperglycemia Diseases 0.000 description 2
239000003456 ion exchange resin Substances 0.000 description 2
229920003303 ion-exchange polymer Polymers 0.000 description 2
238000002955 isolation Methods 0.000 description 2
230000007935 neutral effect Effects 0.000 description 2
235000020824 obesity Nutrition 0.000 description 2
239000000049 pigment Substances 0.000 description 2
229920001282 polysaccharide Polymers 0.000 description 2
239000005017 polysaccharide Substances 0.000 description 2
229920001296 polysiloxane Polymers 0.000 description 2
238000001556 precipitation Methods 0.000 description 2
230000008569 process Effects 0.000 description 2
YGSDEFSMJLZEOE-UHFFFAOYSA-N salicylic acid Chemical compound OC(=O)C1=CC=CC=C1O YGSDEFSMJLZEOE-UHFFFAOYSA-N 0.000 description 2
239000002904 solvent Substances 0.000 description 2
241000894007 species Species 0.000 description 2
231100000820 toxicity test Toxicity 0.000 description 2
238000005303 weighing Methods 0.000 description 2
239000001052 yellow pigment Substances 0.000 description 2
BBBFYZOJHSYQMW-LGDQNDJISA-N (2s)-2,4-diamino-4-oxobutanoic acid;(2r,3s,4r,5r)-2,3,4,5,6-pentahydroxyhexanal Chemical compound OC(=O)[C@@H](N)CC(N)=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O BBBFYZOJHSYQMW-LGDQNDJISA-N 0.000 description 1
NWUYHJFMYQTDRP-UHFFFAOYSA-N 1,2-bis(ethenyl)benzene;1-ethenyl-2-ethylbenzene;styrene Chemical compound C=CC1=CC=CC=C1.CCC1=CC=CC=C1C=C.C=CC1=CC=CC=C1C=C NWUYHJFMYQTDRP-UHFFFAOYSA-N 0.000 description 1
OHVLMTFVQDZYHP-UHFFFAOYSA-N 1-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)-2-[4-[2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidin-5-yl]piperazin-1-yl]ethanone Chemical compound N1N=NC=2CN(CCC=21)C(CN1CCN(CC1)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F)=O OHVLMTFVQDZYHP-UHFFFAOYSA-N 0.000 description 1
LDXJRKWFNNFDSA-UHFFFAOYSA-N 2-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)-1-[4-[2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidin-5-yl]piperazin-1-yl]ethanone Chemical compound C1CN(CC2=NNN=C21)CC(=O)N3CCN(CC3)C4=CN=C(N=C4)NCC5=CC(=CC=C5)OC(F)(F)F LDXJRKWFNNFDSA-UHFFFAOYSA-N 0.000 description 1
JQMFQLVAJGZSQS-UHFFFAOYSA-N 2-[4-[2-(2,3-dihydro-1H-inden-2-ylamino)pyrimidin-5-yl]piperazin-1-yl]-N-(2-oxo-3H-1,3-benzoxazol-6-yl)acetamide Chemical compound C1C(CC2=CC=CC=C12)NC1=NC=C(C=N1)N1CCN(CC1)CC(=O)NC1=CC2=C(NC(O2)=O)C=C1 JQMFQLVAJGZSQS-UHFFFAOYSA-N 0.000 description 1
JVKRKMWZYMKVTQ-UHFFFAOYSA-N 2-[4-[2-(2,3-dihydro-1H-inden-2-ylamino)pyrimidin-5-yl]pyrazol-1-yl]-N-(2-oxo-3H-1,3-benzoxazol-6-yl)acetamide Chemical compound C1C(CC2=CC=CC=C12)NC1=NC=C(C=N1)C=1C=NN(C=1)CC(=O)NC1=CC2=C(NC(O2)=O)C=C1 JVKRKMWZYMKVTQ-UHFFFAOYSA-N 0.000 description 1
YLZOPXRUQYQQID-UHFFFAOYSA-N 3-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)-1-[4-[2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidin-5-yl]piperazin-1-yl]propan-1-one Chemical compound N1N=NC=2CN(CCC=21)CCC(=O)N1CCN(CC1)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F YLZOPXRUQYQQID-UHFFFAOYSA-N 0.000 description 1
241000186361 Actinobacteria <class> Species 0.000 description 1
DCXYFEDJOCDNAF-UHFFFAOYSA-N Asparagine Natural products OC(=O)C(N)CC(N)=O DCXYFEDJOCDNAF-UHFFFAOYSA-N 0.000 description 1
208000031648 Body Weight Changes Diseases 0.000 description 1
UXVMQQNJUSDDNG-UHFFFAOYSA-L Calcium chloride Chemical compound [Cl-].[Cl-].[Ca+2] UXVMQQNJUSDDNG-UHFFFAOYSA-L 0.000 description 1
241000233866 Fungi Species 0.000 description 1
108010010803 Gelatin Proteins 0.000 description 1
239000004366 Glucose oxidase Substances 0.000 description 1
108010015776 Glucose oxidase Proteins 0.000 description 1
244000068988 Glycine max Species 0.000 description 1
235000010469 Glycine max Nutrition 0.000 description 1
DCXYFEDJOCDNAF-REOHCLBHSA-N L-asparagine Chemical compound OC(=O)[C@@H](N)CC(N)=O DCXYFEDJOCDNAF-REOHCLBHSA-N 0.000 description 1
FTNIPWXXIGNQQF-UHFFFAOYSA-N Maltopentose Chemical compound OC1C(O)C(O)C(CO)OC1OC1C(CO)OC(OC2C(OC(OC3C(OC(OC4C(OC(O)C(O)C4O)CO)C(O)C3O)CO)C(O)C2O)CO)C(O)C1O FTNIPWXXIGNQQF-UHFFFAOYSA-N 0.000 description 1
229910002651 NO3 Inorganic materials 0.000 description 1
NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 description 1
IOVCWXUNBOPUCH-UHFFFAOYSA-M Nitrite anion Chemical compound [O-]N=O IOVCWXUNBOPUCH-UHFFFAOYSA-M 0.000 description 1
229920005654 Sephadex Polymers 0.000 description 1
239000012507 Sephadex™ Substances 0.000 description 1
VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
238000010521 absorption reaction Methods 0.000 description 1
238000000862 absorption spectrum Methods 0.000 description 1
230000002378 acidificating effect Effects 0.000 description 1
239000004480 active ingredient Substances 0.000 description 1
BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 1
229910052921 ammonium sulfate Inorganic materials 0.000 description 1
235000011130 ammonium sulphate Nutrition 0.000 description 1
239000003242 anti bacterial agent Substances 0.000 description 1
229940088710 antibiotic agent Drugs 0.000 description 1
229960001230 asparagine Drugs 0.000 description 1
235000009582 asparagine Nutrition 0.000 description 1
238000010170 biological method Methods 0.000 description 1
230000004579 body weight change Effects 0.000 description 1
239000001110 calcium chloride Substances 0.000 description 1
229910001628 calcium chloride Inorganic materials 0.000 description 1
239000001913 cellulose Substances 0.000 description 1
229920002678 cellulose Polymers 0.000 description 1
150000001875 compounds Chemical class 0.000 description 1
238000000354 decomposition reaction Methods 0.000 description 1
230000036425 denaturation Effects 0.000 description 1
238000004925 denaturation Methods 0.000 description 1
238000011161 development Methods 0.000 description 1
238000010586 diagram Methods 0.000 description 1
239000003085 diluting agent Substances 0.000 description 1
238000010790 dilution Methods 0.000 description 1
239000012895 dilution Substances 0.000 description 1
150000002016 disaccharides Chemical class 0.000 description 1
201000010099 disease Diseases 0.000 description 1
208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
239000003814 drug Substances 0.000 description 1
239000003937 drug carrier Substances 0.000 description 1
238000005516 engineering process Methods 0.000 description 1
238000002474 experimental method Methods 0.000 description 1
238000005187 foaming Methods 0.000 description 1
235000013373 food additive Nutrition 0.000 description 1
239000002778 food additive Substances 0.000 description 1
238000004108 freeze drying Methods 0.000 description 1
201000005917 gastric ulcer Diseases 0.000 description 1
239000008273 gelatin Substances 0.000 description 1
229920000159 gelatin Polymers 0.000 description 1
235000019322 gelatine Nutrition 0.000 description 1
235000011852 gelatine desserts Nutrition 0.000 description 1
229940116332 glucose oxidase Drugs 0.000 description 1
235000019420 glucose oxidase Nutrition 0.000 description 1
235000011187 glycerol Nutrition 0.000 description 1
235000013882 gravy Nutrition 0.000 description 1
230000007062 hydrolysis Effects 0.000 description 1
238000006460 hydrolysis reaction Methods 0.000 description 1
238000011534 incubation Methods 0.000 description 1
238000002329 infrared spectrum Methods 0.000 description 1
229910052742 iron Inorganic materials 0.000 description 1
239000000463 material Substances 0.000 description 1
238000005259 measurement Methods 0.000 description 1
239000012528 membrane Substances 0.000 description 1
238000002156 mixing Methods 0.000 description 1
235000015097 nutrients Nutrition 0.000 description 1
235000016709 nutrition Nutrition 0.000 description 1
230000035764 nutrition Effects 0.000 description 1
239000006877 oatmeal agar Substances 0.000 description 1
229920001542 oligosaccharide Polymers 0.000 description 1
150000002482 oligosaccharides Chemical class 0.000 description 1
230000003287 optical effect Effects 0.000 description 1
FJKROLUGYXJWQN-UHFFFAOYSA-N papa-hydroxy-benzoic acid Natural products OC(=O)C1=CC=C(O)C=C1 FJKROLUGYXJWQN-UHFFFAOYSA-N 0.000 description 1
230000035699 permeability Effects 0.000 description 1
108090000765 processed proteins & peptides Proteins 0.000 description 1
230000000069 prophylactic effect Effects 0.000 description 1
238000011160 research Methods 0.000 description 1
229960004889 salicylic acid Drugs 0.000 description 1
238000005185 salting out Methods 0.000 description 1
150000003839 salts Chemical class 0.000 description 1
238000000926 separation method Methods 0.000 description 1
239000002689 soil Substances 0.000 description 1
208000024891 symptom Diseases 0.000 description 1
229940124597 therapeutic agent Drugs 0.000 description 1
238000004809 thin layer chromatography Methods 0.000 description 1
238000012546 transfer Methods 0.000 description 1
238000000108 ultra-filtration Methods 0.000 description 1
230000004580 weight loss Effects 0.000 description 1

Classifications

- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor

Landscapes

Life Sciences & Earth Sciences (AREA)
Chemical & Material Sciences (AREA)
Engineering & Computer Science (AREA)
Health & Medical Sciences (AREA)
Genetics & Genomics (AREA)
Biotechnology (AREA)
Organic Chemistry (AREA)
Zoology (AREA)
Bioinformatics & Cheminformatics (AREA)
Wood Science & Technology (AREA)
Tropical Medicine & Parasitology (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
Virology (AREA)
Biochemistry (AREA)
General Engineering & Computer Science (AREA)
General Health & Medical Sciences (AREA)
Microbiology (AREA)
Preparation Of Compounds By Using Micro-Organisms (AREA)
Micro-Organisms Or Cultivation Processes Thereof (AREA)
Coloring Foods And Improving Nutritive Qualities (AREA)
Saccharide Compounds (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Polysaccharides And Polysaccharide Derivatives (AREA)

JP1171752A 1988-08-09 1989-07-03 新規な微生物ストレプトマイセスｓｐ．ｙ―１２５およびこれらからアミラーゼ阻害物質を製造する方法 Granted JPH02131571A (ja)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
KR88-10151		1988-08-09
KR1019880010151A KR900007643B1 (ko)	1988-08-09	1988-08-09	신규 미생물 스트렙토마이세스 sp.Y-125 및 이로부터 제조되는 아밀레이스 저해제

Publications (2)

Publication Number	Publication Date
JPH02131571A JPH02131571A (ja)	1990-05-21
JPH0517831B2 true JPH0517831B2 (ko)	1993-03-10

Family

ID=19276821

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
JP1171752A Granted JPH02131571A (ja)	1988-08-09	1989-07-03	新規な微生物ストレプトマイセスｓｐ．ｙ―１２５およびこれらからアミラーゼ阻害物質を製造する方法

Country Status (2)

Country	Link
JP (1)	JPH02131571A (ko)
KR (1)	KR900007643B1 (ko)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
NL1026239C2 (nl) *	2004-05-19	2005-11-22	Ten Cate Thiolon Bv	Werkwijze voor het vervaardigen van een kunststofvezel voor toepassing in een kunstgrassportveld alsmede een dergelijke kunststofvezel.
CN114540213B (zh) *	2021-11-11	2024-03-19	中国热带农业科学院海口实验站	一种具有抑菌活性的放线菌及其应用

1988
- 1988-08-09 KR KR1019880010151A patent/KR900007643B1/ko not_active IP Right Cessation
1989
- 1989-07-03 JP JP1171752A patent/JPH02131571A/ja active Granted

Also Published As

Publication number	Publication date
KR900007643B1 (ko)	1990-10-17
KR900003360A (ko)	1990-03-26
JPH02131571A (ja)	1990-05-21

Publication	Publication Date	Title
US3067099A (en)	1962-12-04	Vancomycin and method for its preparation
JPS6216638B2 (ko)	1987-04-14
IE893482L (en)	1990-04-28	The glycosidase inhibitor salbostatin, process for its¹preparation, and its use
US3919049A (en)	1975-11-11	Process for preparing {62 -galactosidase
US4010258A (en)	1977-03-01	Microbial amylase inhibitor and preparation thereof with the use of streptomyces diasticus var. amylostaticus
EP0468411B1 (en)	1995-11-29	A mutant of bacterium Clostridium histolyticum, a process for the obtaining thereof, and its use in the production of clostripain-free collagenase
FR2520379A1 (fr)	1983-07-29	Procede de preparation d'un disaccharide-tripeptide et d'un disaccharide-tetrapeptide possedant des proprietes immunostimulantes
JPS59118712A (ja)	1984-07-09	抗腫瘍剤及びその製造法
DK143906B (da)	1981-10-26	Fremgangsmaade til fremstilling af amylase ved dyrkning af en streptomycesstamme i et naeringssubstrat der indeholder carbon- og nitrogenkilder
US3806421A (en)	1974-04-23	Amylase inhibitor and method of producing the same
US4229539A (en)	1980-10-21	β-Galactosidase and production thereof
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