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IS5884A - Aðferð til framleiðslu á hreinu sítalóprami - Google Patents

Aðferð til framleiðslu á hreinu sítalóprami

Info

Publication number
IS5884A
IS5884A IS5884A IS5884A IS5884A IS 5884 A IS5884 A IS 5884A IS 5884 A IS5884 A IS 5884A IS 5884 A IS5884 A IS 5884A IS 5884 A IS5884 A IS 5884A
Authority
IS
Iceland
Prior art keywords
production
pure citalopram
citalopram
pure
Prior art date
Application number
IS5884A
Other languages
English (en)
Inventor
Castellin Andrea
Sbrogiþ Federico
Volpe Giulio
Original Assignee
H. Lundbeck A/S
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H. Lundbeck A/S filed Critical H. Lundbeck A/S
Publication of IS5884A publication Critical patent/IS5884A/is

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87Benzo [c] furans; Hydrogenated benzo [c] furans
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
IS5884A 2000-12-28 2001-03-09 Aðferð til framleiðslu á hreinu sítalóprami IS5884A (is)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DKPA200001943 2000-12-28

Publications (1)

Publication Number Publication Date
IS5884A true IS5884A (is) 2002-06-28

Family

ID=8159933

Family Applications (1)

Application Number Title Priority Date Filing Date
IS5884A IS5884A (is) 2000-12-28 2001-03-09 Aðferð til framleiðslu á hreinu sítalóprami

Country Status (41)

Country Link
US (2) US6855834B2 (is)
EP (1) EP1181272B1 (is)
JP (1) JP2003519121A (is)
KR (1) KR100430746B1 (is)
CN (1) CN1366526A (is)
AR (1) AR029898A1 (is)
AT (2) ATE222899T1 (is)
AU (3) AU3920201A (is)
BE (2) BE1013417A6 (is)
BG (1) BG106219A (is)
BR (1) BR0106271A (is)
CA (1) CA2359810C (is)
CH (1) CH691536A5 (is)
CZ (1) CZ293140B6 (is)
DE (1) DE60100016T2 (is)
DK (1) DK1181272T3 (is)
EA (1) EA003459B1 (is)
ES (2) ES2181663T3 (is)
FI (2) FI108640B (is)
FR (1) FR2818977B1 (is)
GB (2) GB2356199B (is)
GR (1) GR20010100131A (is)
HK (1) HK1049332A1 (is)
HR (1) HRP20020005A2 (is)
HU (2) HU0101028D0 (is)
IE (2) IES20010253A2 (is)
IL (1) IL147162A0 (is)
IS (1) IS5884A (is)
IT (1) ITMI20010604A1 (is)
MX (1) MXPA01013336A (is)
NL (1) NL1017534C1 (is)
NO (1) NO313047B1 (is)
NZ (1) NZ516299A (is)
PL (1) PL353369A1 (is)
PT (1) PT1181272E (is)
SE (1) SE0103044L (is)
SK (1) SK284418B6 (is)
TR (1) TR200200018T1 (is)
UA (1) UA71635C2 (is)
WO (1) WO2001047877A2 (is)
ZA (1) ZA200110133B (is)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
DE69907037T3 (de) * 1999-04-14 2010-02-18 H. Lundbeck A/S Verfahren zur herstellung von citalopram
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
DK1228056T3 (da) 1999-10-25 2005-01-24 Lundbeck & Co As H Fremgangsmåde til fremstilling af citalopram
ES2169709A1 (es) 1999-10-25 2002-07-01 Lundbeck & Co As H Metodo para la preparacion de citalopram
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
PL355532A1 (en) 1999-12-28 2004-05-04 H.Lundbeck A/S Method for the preparation of citalopram
AU1858400A (en) 1999-12-30 2001-07-16 H. Lundbeck A/S Method for the preparation of citalopram
KR100660802B1 (ko) 2000-01-14 2006-12-26 하. 룬트벡 아크티에 셀스카브 5-시아노프탈리드의 제조 방법
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
IES20010206A2 (en) 2000-03-13 2002-03-06 Lundbeck & Co As H Method for the preparation of citalopram
CA2402553A1 (en) * 2000-03-13 2001-09-20 H. Lundbeck A/S Stepwise alkylation of 5-substituted 1-(4-fluorophenyl)-1,3-dihydroisobenzofurans
EA200200969A1 (ru) 2000-03-13 2003-02-27 Х.Лундбекк А/С Способ получения циталопрама
HUP0300178A2 (en) 2000-03-14 2003-05-28 Lundbeck & Co As H Method for the preparation of citalopram
IL151487A0 (en) * 2000-03-16 2003-04-10 Lundbeck & Co As H Method for the preparation of 5-cyano-1-(4-flourophenyl)-1,3-dihydroisobenzofurans
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
IL144816A (en) 2000-08-18 2005-09-25 Lundbeck & Co As H Method for the preparation of citalopram
BR0106272A (pt) 2000-12-22 2004-06-15 Lundbeck & Co As H Processo para preparação de citalopram puro
CN1366526A (zh) 2000-12-28 2002-08-28 H·隆德贝克有限公司 纯西酞普兰的制备方法
GB2376945A (en) * 2001-06-27 2002-12-31 Cipla Ltd Citalopram preparation
AU2003222435A1 (en) 2002-01-07 2003-07-24 Sun Pharmaceutical Industries Limited Process for the preparation of 1-(3-(dimethylamino)propyl)-1-(4-fluorophenyl)- 1,3-dihydro-5-isobenzofuran carbonitrile
ES2194597B2 (es) * 2002-01-25 2004-08-01 Esteve Quimica, S.A. Procedimiento para la obtencion de citalopram.
GB2386119A (en) * 2002-02-27 2003-09-10 Cipla Ltd Purification of citalopram
GB0204607D0 (en) * 2002-02-27 2002-04-10 Matrix Lab Ltd Process
EP1346989A1 (en) * 2002-03-21 2003-09-24 Jubilant Organosys Limited Improved process for the preparation of citalopram and its hydrobromide
US20050154052A1 (en) * 2003-03-24 2005-07-14 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
US7019153B2 (en) 2003-06-10 2006-03-28 Sun Pharmaceutical Industries Limited Process for hydrogenolysis of [1-(3-dimethylamino)propyl)]-1-(4-fluorophenyl)-1,3-dihydro-5-halo-isobenzofuran acetamido-3-substituted-3-cephem-4-carboxylic acid
CN100569765C (zh) 2003-12-19 2009-12-16 杭州民生药业集团有限公司 西酞普兰中间体晶体碱
TWI358407B (en) * 2005-06-22 2012-02-21 Lundbeck & Co As H Crystalline base of escitalopram and orodispersibl
US7834201B2 (en) 2005-06-22 2010-11-16 H. Lundbeck A/S Crystalline base of escitalopram and orodispersible tablets comprising escitalopram base

Family Cites Families (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL135959C (is) 1964-12-23
GB1143703A (is) 1965-03-18
DE1619713A1 (de) * 1967-03-29 1970-12-17 Leybold Heraeus Gmbh & Co Kg Vorrichtung zur Vakuum- und Kurzwegdestillation
DE2135085C3 (de) 1971-07-14 1981-12-03 Basf Ag, 6700 Ludwigshafen Verfahren zur Wiedergewinnung von Caprolactam aus einem Gemisch, das Caprolactam und dessen Oligomere enthält
DE2442426C2 (de) 1974-09-05 1983-04-07 Bayer Ag, 5090 Leverkusen Diisocyanatodiketene, Verfahren zu deren Herstellung und deren Verwendung
GB1526331A (en) * 1976-01-14 1978-09-27 Kefalas As Phthalanes
IT8020902A0 (it) 1980-03-25 1980-03-25 Snia Viscosa Procedimento ed apparecchiatura per la separazione continua per via termica di miscele liquide dicomposti termolabili.
JPS6082101A (ja) 1983-10-13 1985-05-10 Mitsui Toatsu Chem Inc 高沸点重合性化合物の薄膜蒸留による精製方法
GB8419963D0 (en) 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) * 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
FR2656305B1 (fr) 1989-12-22 1992-04-10 Norsolor Sa Procede de purification du (meth)acrylate de glycidyle.
US5296507A (en) 1990-09-06 1994-03-22 H.Lundbeck A/S Treatment of cerbrovascular disorders
US5582692A (en) 1994-10-07 1996-12-10 Artisan Industries, Inc. Method for the purification of vitamin E
AU723333B2 (en) 1996-05-21 2000-08-24 Resolution Specialty Materials Llc Process for the purification of glycidyl esters from epihalohydrin and carboxylic acids
US6136991A (en) * 1996-05-21 2000-10-24 Exxon Chemical Patents Inc. Glycidyl ester adducts having increased glass transition temperatures
DE19626659A1 (de) 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
AU737610B2 (en) 1997-07-08 2001-08-23 H. Lundbeck A/S Method for the preparation of citalopram
DE19734673A1 (de) 1997-08-11 1999-02-18 Rwe Dea Ag Verfahren zur Herstellung von metallfreien Guerbetalkoholen
UA62985C2 (en) 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
TR200001341T2 (tr) 1997-11-11 2000-11-21 H. Lundbeck A/S Sitalopramın hazırlandığı metot
DE69920329T3 (de) 1998-06-19 2009-07-09 Shin-Etsu Chemical Co., Ltd. Destillationsverfahren für (Meth)acryloxysilane
ES2189502T3 (es) * 1998-10-20 2003-07-01 Lundbeck & Co As H Metodo para la prevencion de citalopram.
UA70979C2 (uk) 1998-12-23 2004-11-15 Х. Луннбек А/С Спосіб одержання 5-ціанофталіду
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
DE69907037T3 (de) 1999-04-14 2010-02-18 H. Lundbeck A/S Verfahren zur herstellung von citalopram
ITMI991579A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ES2169709A1 (es) 1999-10-25 2002-07-01 Lundbeck & Co As H Metodo para la preparacion de citalopram
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate
GB0005477D0 (en) 2000-03-07 2000-04-26 Resolution Chemicals Limited Process for the preparation of citalopram
BR0106272A (pt) 2000-12-22 2004-06-15 Lundbeck & Co As H Processo para preparação de citalopram puro
CN1366526A (zh) 2000-12-28 2002-08-28 H·隆德贝克有限公司 纯西酞普兰的制备方法
US6781003B1 (en) * 2003-06-09 2004-08-24 Aurobindo Pharma Ltd. Preparation of pure citalopram

Also Published As

Publication number Publication date
HRP20020005A2 (en) 2003-04-30
CA2359810A1 (en) 2001-07-05
PL353369A1 (en) 2003-11-17
GR20010100131A (el) 2002-10-09
IES20010253A2 (en) 2002-03-06
US20030178295A1 (en) 2003-09-25
IES20010632A2 (en) 2002-03-06
DE60100016T2 (de) 2003-04-17
JP2003519121A (ja) 2003-06-17
US6855834B2 (en) 2005-02-15
CZ293140B6 (cs) 2004-02-18
AU2001100399B4 (en) 2002-03-21
FI20011578A0 (fi) 2001-07-26
AT4368U1 (de) 2001-06-25
ITMI20010604A0 (it) 2001-03-22
EA003459B1 (ru) 2003-06-26
FI20010501A0 (fi) 2001-03-13
GB2356199A (en) 2001-05-16
HUP0102818A2 (hu) 2001-12-28
GB0117095D0 (en) 2001-09-05
CA2359810C (en) 2002-11-05
GB2361697A (en) 2001-10-31
ES2170733B1 (es) 2003-12-16
US20020087012A1 (en) 2002-07-04
NO313047B1 (no) 2002-08-05
EP1181272B1 (en) 2002-08-28
EP1181272A2 (en) 2002-02-27
NO20011272D0 (no) 2001-03-13
UA71635C2 (uk) 2004-12-15
NL1017534C1 (nl) 2001-04-26
NZ516299A (en) 2002-12-20
WO2001047877A2 (en) 2001-07-05
FI108640B (fi) 2002-02-28
SK284418B6 (sk) 2005-04-01
NO20011272L (no) 2002-07-01
CZ2001891A3 (cs) 2002-08-14
DK1181272T3 (da) 2002-12-30
FR2818977A1 (fr) 2002-07-05
WO2001047877A3 (en) 2001-12-27
PT1181272E (pt) 2003-01-31
ATE222899T1 (de) 2002-09-15
ES2170733A1 (es) 2002-08-01
HU0102818D0 (en) 2001-09-28
SK18472001A3 (sk) 2002-05-09
ES2181663T3 (es) 2003-03-01
BG106219A (en) 2002-08-30
SE0103044D0 (sv) 2001-09-14
SE0103044L (sv) 2002-06-29
FR2818977B1 (fr) 2003-12-05
GB0105981D0 (en) 2001-05-02
BR0106271A (pt) 2002-05-21
CN1366526A (zh) 2002-08-28
EA200200016A1 (ru) 2002-04-25
AU3920201A (en) 2001-07-09
AU750006B1 (en) 2002-07-11
HK1049332A1 (zh) 2003-05-09
ZA200110133B (en) 2003-01-13
BE1013417A6 (fr) 2001-12-04
AR029898A1 (es) 2003-07-23
TR200200018T1 (tr) 2002-06-21
GB2356199B (en) 2001-10-03
MXPA01013336A (es) 2002-07-09
ITMI20010604A1 (it) 2002-09-22
IL147162A0 (en) 2002-08-14
HU0101028D0 (en) 2001-05-28
KR100430746B1 (ko) 2004-05-10
CH691536A5 (de) 2001-08-15
KR20020073379A (ko) 2002-09-26
BE1013316A6 (fr) 2001-11-06
AU2001100399A4 (en) 2001-11-01
DE60100016D1 (de) 2002-10-02
HUP0102818A3 (en) 2003-07-28

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