IL296106A - הרכבים ושיטות לעיכוב ביטוי של טרנסתירטין (ttr) - Google Patents
הרכבים ושיטות לעיכוב ביטוי של טרנסתירטין (ttr)Info
- Publication number
- IL296106A IL296106A IL296106A IL29610622A IL296106A IL 296106 A IL296106 A IL 296106A IL 296106 A IL296106 A IL 296106A IL 29610622 A IL29610622 A IL 29610622A IL 296106 A IL296106 A IL 296106A
- Authority
- IL
- Israel
- Prior art keywords
- ttr
- rnai agent
- fixed dose
- double stranded
- phosphate
- Prior art date
Links
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Applications Claiming Priority (2)
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US202062985950P | 2020-03-06 | 2020-03-06 | |
PCT/US2021/021049 WO2021178778A1 (en) | 2020-03-06 | 2021-03-05 | Compositions and methods for inhibiting expression of transthyretin (ttr) |
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IL296106A true IL296106A (he) | 2022-11-01 |
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JP (1) | JP2023516748A (he) |
KR (1) | KR20220152270A (he) |
CN (1) | CN115461460A (he) |
AU (1) | AU2021232029A1 (he) |
CA (1) | CA3174473A1 (he) |
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IL281434B2 (he) | 2008-10-20 | 2023-09-01 | Alnylam Pharmaceuticals Inc | תרכובות ושיטות לעיכוב ביטוי של טראנסתיראטין |
PL3329002T3 (pl) | 2015-07-31 | 2021-04-19 | Alnylam Pharmaceuticals, Inc. | Kompozycje irna transtyretyny (ttr) i sposoby ich zastosowania do leczenia lub zapobiegania chorobom związanym z ttr |
KR20200089656A (ko) | 2017-09-19 | 2020-07-27 | 알닐람 파마슈티칼스 인코포레이티드 | 트랜스타이레틴(ttr) 매개 아밀로이드증을 치료하기 위한 조성물 및 방법 |
WO2023014677A1 (en) | 2021-08-03 | 2023-02-09 | Alnylam Pharmaceuticals, Inc. | Transthyretin (ttr) irna compositions and methods of use thereof |
TW202440923A (zh) * | 2022-12-16 | 2024-10-16 | 美商安進公司 | 用於抑制ttr表現的rnai構建體及其使用方法 |
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- 2021-03-05 EP EP21714746.1A patent/EP4114949A1/en active Pending
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AU2021232029A1 (en) | 2022-10-06 |
WO2021178778A1 (en) | 2021-09-10 |
CN115461460A (zh) | 2022-12-09 |
EP4114949A1 (en) | 2023-01-11 |
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