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HUE062189T2 - Aktivin-ACTRII-antagonisták és alkalmazások mielodiszpláziás szindróma kezelésére - Google Patents

Aktivin-ACTRII-antagonisták és alkalmazások mielodiszpláziás szindróma kezelésére

Info

Publication number
HUE062189T2
HUE062189T2 HUE15865213A HUE15865213A HUE062189T2 HU E062189 T2 HUE062189 T2 HU E062189T2 HU E15865213 A HUE15865213 A HU E15865213A HU E15865213 A HUE15865213 A HU E15865213A HU E062189 T2 HUE062189 T2 HU E062189T2
Authority
HU
Hungary
Prior art keywords
activin
applications
treatment
myelodysplastic syndrome
actrii antagonists
Prior art date
Application number
HUE15865213A
Other languages
English (en)
Inventor
Kenneth M Attie
Christopher Rovaldi
Abderrahmane Laadem
Original Assignee
Celgene Corp
Acceleron Pharma Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celgene Corp, Acceleron Pharma Inc filed Critical Celgene Corp
Publication of HUE062189T2 publication Critical patent/HUE062189T2/hu

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/179Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/02Antineoplastic agents specific for leukemia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/483Physical analysis of biological material
    • G01N33/487Physical analysis of biological material of liquid biological material
    • G01N33/49Blood
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/30Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Biomedical Technology (AREA)
  • Organic Chemistry (AREA)
  • Hematology (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Cell Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ecology (AREA)
  • Epidemiology (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Pathology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Food Science & Technology (AREA)
  • Urology & Nephrology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Diabetes (AREA)
  • Oncology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HUE15865213A 2014-12-03 2015-12-03 Aktivin-ACTRII-antagonisták és alkalmazások mielodiszpláziás szindróma kezelésére HUE062189T2 (hu)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US201462086977P 2014-12-03 2014-12-03
US201462088478P 2014-12-05 2014-12-05
US201562153872P 2015-04-28 2015-04-28
US201562173782P 2015-06-10 2015-06-10
US201562218728P 2015-09-15 2015-09-15

Publications (1)

Publication Number Publication Date
HUE062189T2 true HUE062189T2 (hu) 2023-09-28

Family

ID=56092426

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE15865213A HUE062189T2 (hu) 2014-12-03 2015-12-03 Aktivin-ACTRII-antagonisták és alkalmazások mielodiszpláziás szindróma kezelésére

Country Status (26)

Country Link
US (1) US11471510B2 (hu)
EP (2) EP4233889A3 (hu)
JP (2) JP2018501307A (hu)
KR (1) KR102556991B1 (hu)
CN (2) CN107533040B (hu)
AU (2) AU2015358469B2 (hu)
BR (1) BR112017011722A2 (hu)
CA (1) CA2969572A1 (hu)
CY (1) CY1126033T1 (hu)
DK (1) DK3227675T3 (hu)
ES (1) ES2946160T3 (hu)
FI (1) FI3227675T3 (hu)
HK (2) HK1245397A1 (hu)
HR (1) HRP20230504T1 (hu)
HU (1) HUE062189T2 (hu)
IL (1) IL252631B2 (hu)
LT (1) LT3227675T (hu)
MD (1) MD4801C1 (hu)
NZ (2) NZ770419A (hu)
PL (1) PL3227675T3 (hu)
PT (1) PT3227675T (hu)
RS (1) RS64214B1 (hu)
SI (1) SI3227675T1 (hu)
SM (1) SMT202300166T1 (hu)
TW (2) TWI730949B (hu)
WO (1) WO2016090077A1 (hu)

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CA3082146A1 (en) 2017-11-09 2019-05-16 Keros Therapeutics, Inc. Activin receptor type iia variants and methods of use thereof
CN112292144A (zh) 2018-01-12 2021-01-29 科乐斯疗法公司 激活素受体iib型变体及其使用方法
WO2019213016A1 (en) * 2018-04-30 2019-11-07 The Children's Hospital Of Philadelphia Methods of improving anemias by combining agents
EP3873501A4 (en) * 2018-10-31 2022-07-13 Celgene Corporation TREATMENT OF ANEMIA DUE TO VERY WEAK, WEAK, OR INTERMEDIATE MYELODYSPLASTIC SYNDROMES IN SUBJECTS WITH CROWN SIDEROBLASTS USING ACTIVIN-ACTRII LIGAND TRAPS
WO2021189010A1 (en) * 2020-03-20 2021-09-23 Keros Therapeutics, Inc. Methods of using activin receptor type iib variants
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