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HUE041571T2 - RAAV-guanilát-cikláz-készítmények és ejárások 1-es típusú Leber-féle veleszületett vakság (LCA1) kezelésére - Google Patents

RAAV-guanilát-cikláz-készítmények és ejárások 1-es típusú Leber-féle veleszületett vakság (LCA1) kezelésére

Info

Publication number
HUE041571T2
HUE041571T2 HUE11726973A HUE11726973A HUE041571T2 HU E041571 T2 HUE041571 T2 HU E041571T2 HU E11726973 A HUE11726973 A HU E11726973A HU E11726973 A HUE11726973 A HU E11726973A HU E041571 T2 HUE041571 T2 HU E041571T2
Authority
HU
Hungary
Prior art keywords
lca1
raav
methods
guanylate cyclase
congenital amaurosis
Prior art date
Application number
HUE11726973A
Other languages
English (en)
Inventor
Shannon Elizabeth Boye
William W Hauswirth
Sanford Leon Boye
Original Assignee
Univ Florida
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Florida filed Critical Univ Florida
Publication of HUE041571T2 publication Critical patent/HUE041571T2/hu

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    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C12N15/864—Parvoviral vectors, e.g. parvovirus, densovirus
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    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85—Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86—Viral vectors
    • C12N15/861—Adenoviral vectors
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    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
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    • C12N2750/14011—Parvoviridae
    • C12N2750/14111—Dependovirus, e.g. adenoassociated viruses
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    • C12N2830/00—Vector systems having a special element relevant for transcription
    • C12N2830/80—Vector systems having a special element relevant for transcription from vertebrates
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  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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HUE11726973A 2010-04-23 2011-04-22 RAAV-guanilát-cikláz-készítmények és ejárások 1-es típusú Leber-féle veleszületett vakság (LCA1) kezelésére HUE041571T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US32752110P 2010-04-23 2010-04-23

Publications (1)

Publication Number Publication Date
HUE041571T2 true HUE041571T2 (hu) 2019-05-28

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HUE11726973A HUE041571T2 (hu) 2010-04-23 2011-04-22 RAAV-guanilát-cikláz-készítmények és ejárások 1-es típusú Leber-féle veleszületett vakság (LCA1) kezelésére

Country Status (28)

Country Link
US (3) US9816108B2 (hu)
EP (3) EP2561067B1 (hu)
JP (4) JP5897549B2 (hu)
KR (3) KR101984145B1 (hu)
CN (2) CN105821079B (hu)
AU (1) AU2011242527B2 (hu)
BR (1) BR112012026730A8 (hu)
CA (1) CA2796399C (hu)
CL (1) CL2012002969A1 (hu)
CO (1) CO6640236A2 (hu)
CY (1) CY1123008T1 (hu)
DK (2) DK2561067T3 (hu)
EA (2) EA202091105A1 (hu)
ES (2) ES2711256T3 (hu)
HR (1) HRP20190144T1 (hu)
HU (1) HUE041571T2 (hu)
IL (2) IL222651B (hu)
LT (1) LT2561067T (hu)
MX (1) MX351865B (hu)
NZ (1) NZ602897A (hu)
PL (2) PL3486320T3 (hu)
PT (2) PT3486320T (hu)
RS (1) RS58434B1 (hu)
SG (4) SG184876A1 (hu)
SI (1) SI2561067T1 (hu)
SM (1) SMT201900097T1 (hu)
TR (1) TR201901377T4 (hu)
WO (1) WO2011133933A2 (hu)

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WO2020154535A1 (en) * 2019-01-23 2020-07-30 University Of Florida Research Foundation, Incorporated Highly efficient transduction and lateral spread in the retina by a novel aav virus enhanced by rational design
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JP2024016295A (ja) * 2020-11-30 2024-02-07 タカラバイオ株式会社 二価の陽イオンを利用した非エンベロープウイルスの製造方法
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