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HUE026595T2 - Aptamer NGF-hez és alkalmazása - Google Patents

Aptamer NGF-hez és alkalmazása

Info

Publication number
HUE026595T2
HUE026595T2 HUE09816140A HUE09816140A HUE026595T2 HU E026595 T2 HUE026595 T2 HU E026595T2 HU E09816140 A HUE09816140 A HU E09816140A HU E09816140 A HUE09816140 A HU E09816140A HU E026595 T2 HUE026595 T2 HU E026595T2
Authority
HU
Hungary
Prior art keywords
ngf
aptamer
Prior art date
Application number
HUE09816140A
Other languages
English (en)
Inventor
Ling Jin
Shin Miyakawa
Masatoshi Fujiwara
Yoshikazu Nakamura
Hisanao Hiramatsu
Original Assignee
Ribomic Inc
Fujimoto Seiyaku Kk
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ribomic Inc, Fujimoto Seiyaku Kk filed Critical Ribomic Inc
Publication of HUE026595T2 publication Critical patent/HUE026595T2/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/115—Aptamers, i.e. nucleic acids binding a target molecule specifically and with high affinity without hybridising therewith ; Nucleic acids binding to non-nucleic acids, e.g. aptamers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7088—Compounds having three or more nucleosides or nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/14—Extraction; Separation; Purification
    • C07K1/16—Extraction; Separation; Purification by chromatography
    • C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2310/00—Structure or type of the nucleic acid
    • C12N2310/10—Type of nucleic acid
    • C12N2310/16—Aptamers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Microbiology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Epidemiology (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
HUE09816140A 2008-09-24 2009-09-18 Aptamer NGF-hez és alkalmazása HUE026595T2 (hu)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2008244982 2008-09-24

Publications (1)

Publication Number Publication Date
HUE026595T2 true HUE026595T2 (hu) 2016-06-28

Family

ID=42059724

Family Applications (1)

Application Number Title Priority Date Filing Date
HUE09816140A HUE026595T2 (hu) 2008-09-24 2009-09-18 Aptamer NGF-hez és alkalmazása

Country Status (16)

Country Link
US (1) US10260070B2 (hu)
EP (1) EP2354225B1 (hu)
JP (1) JP5602020B2 (hu)
KR (1) KR101694559B1 (hu)
CN (1) CN102171339B (hu)
AU (1) AU2009297626B2 (hu)
BR (1) BRPI0919268B8 (hu)
CA (1) CA2738129C (hu)
DK (1) DK2354225T3 (hu)
ES (1) ES2543222T3 (hu)
HU (1) HUE026595T2 (hu)
IL (1) IL211929A0 (hu)
MX (1) MX2011003144A (hu)
RU (1) RU2011116175A (hu)
WO (1) WO2010035725A1 (hu)
ZA (1) ZA201102682B (hu)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8975026B2 (en) 2007-01-16 2015-03-10 Somalogic, Inc. Method for generating aptamers with improved off-rates
EP2542266A4 (en) 2010-03-03 2013-10-23 Somalogic Inc 4-1BB-BINDING APTAMERS AND USE THEREOF IN THE TREATMENT OF DISEASES AND DISORDERS
AU2011230388B2 (en) * 2010-03-24 2016-09-08 Fujimoto Pharmaceutical Corporation Aptamer for NGF and use thereof
EP2558586B1 (en) 2010-04-12 2016-10-12 Somalogic, Inc. APTAMERS TO ß-NGF AND THEIR USE IN TREATING ß-NGF MEDIATED DISEASES AND DISORDERS
JP5696830B2 (ja) * 2010-04-27 2015-04-08 株式会社アップウェル Ｐａｒ−２活性化阻害物質
JP2012024026A (ja) * 2010-07-23 2012-02-09 Tdk Corp Ｓｍ菌特異的アプタマー、Ｓｍ菌増殖抑制剤及びＳｍ菌の検出方法
RU2606622C2 (ru) 2010-08-31 2017-01-10 Бионуре Фарма, С.Л. Агонисты рецепторов нейротрофинов и их применение в качестве лекарственных средств
WO2013047844A1 (ja) 2011-09-28 2013-04-04 株式会社リボミック Ｎｇｆに対するアプタマー及びその用途

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0786469T3 (da) * 1990-06-11 2006-07-10 Gilead Sciences Inc Nukleinsyreligander
US5660985A (en) * 1990-06-11 1997-08-26 Nexstar Pharmaceuticals, Inc. High affinity nucleic acid ligands containing modified nucleotides
EP0668931B1 (en) 1992-09-29 2006-01-04 Gilead Sciences, Inc. Nucleic acid ligands and methods for producing the same
EP1793006A3 (en) 1993-09-08 2007-08-22 Gilead Sciences, Inc. Nucleic acid ligands and improved methods for producing the same
WO2003070984A1 (en) 2002-02-15 2003-08-28 Somalogic, Inc. Methods and reagents for detecting target binding by nucleic acid ligands
US20030054360A1 (en) * 1999-01-19 2003-03-20 Larry Gold Method and apparatus for the automated generation of nucleic acid ligands
US7638464B2 (en) * 1999-04-26 2009-12-29 Biocept, Inc. Three dimensional format biochips
JP2003525037A (ja) * 2000-02-11 2003-08-26 リボザイム・ファーマシューティカルズ・インコーポレーテッド Ｃｄ２０およびｎｏｇｏ遺伝子発現の調節および診断のための方法および試薬
US20030077251A1 (en) * 2001-05-23 2003-04-24 Nicolas Escriou Replicons derived from positive strand RNA virus genomes useful for the production of heterologous proteins
US20050043256A1 (en) * 2001-07-30 2005-02-24 Isis Pharmaceuticals, Inc. Antisense modulation of stearoyl-CoA desaturase expression
US20050215506A1 (en) * 2001-12-20 2005-09-29 Bennett C F Modulation of tyrosinase expression
US7255860B2 (en) 2002-10-08 2007-08-14 Rinat Neuroscience Corp. Methods for treating post-surgical pain by administering an anti-nerve growth factor antagonist antibody
BR0315164A (pt) 2002-10-08 2005-08-23 Rinat Neuroscience Corp Métodos para tratar dor pós-cirúrgica administrando um antagonista de fator de crescimento nervoso e composições contendo o mesmo
UA80447C2 (en) 2002-10-08 2007-09-25 Methods for treating pain by administering nerve growth factor antagonist and opioid analgesic
US7250496B2 (en) * 2002-11-14 2007-07-31 Rosetta Genomics Ltd. Bioinformatically detectable group of novel regulatory genes and uses thereof
US7569364B2 (en) 2002-12-24 2009-08-04 Pfizer Inc. Anti-NGF antibodies and methods using same
CA2516454A1 (en) 2003-02-19 2004-09-02 Rinat Neuroscience Corp. Methods for treating pain by administering a nerve growth factor antagonist and an nsaid and compositions containing the same
US20050136395A1 (en) * 2003-05-08 2005-06-23 Affymetrix, Inc Methods for genetic analysis of SARS virus
US7888497B2 (en) * 2003-08-13 2011-02-15 Rosetta Genomics Ltd. Bioinformatically detectable group of novel regulatory oligonucleotides and uses thereof
EP1732949B1 (en) 2004-04-07 2010-01-27 Rinat Neuroscience Corp. Methods for treating bone cancer pain by administering a nerve growth factor antagonist
US7592441B2 (en) * 2004-10-04 2009-09-22 Rosetta Genomics Ltd Liver cancer-related nucleic acids
ZA200903562B (en) 2006-11-14 2010-07-28 Ribomic Inc Aptamer against midkine and use thereof
JP5012135B2 (ja) 2007-03-28 2012-08-29 コニカミノルタアドバンストレイヤー株式会社 超深度画像生成装置
AU2009273052B2 (en) 2008-07-14 2015-09-17 The University Of Tokyo Aptamer against IL-17 and use thereof

Also Published As

Publication number Publication date
US20110251266A1 (en) 2011-10-13
JPWO2010035725A1 (ja) 2012-02-23
WO2010035725A1 (ja) 2010-04-01
CN102171339A (zh) 2011-08-31
AU2009297626A1 (en) 2010-04-01
MX2011003144A (es) 2011-05-19
EP2354225A1 (en) 2011-08-10
CN102171339B (zh) 2017-06-09
ZA201102682B (en) 2012-06-27
RU2011116175A (ru) 2012-10-27
BRPI0919268B8 (pt) 2021-05-25
CA2738129A1 (en) 2010-04-01
ES2543222T3 (es) 2015-08-17
US10260070B2 (en) 2019-04-16
BRPI0919268B1 (pt) 2021-01-12
CA2738129C (en) 2017-11-14
EP2354225B1 (en) 2015-04-22
BRPI0919268A2 (pt) 2017-11-07
JP5602020B2 (ja) 2014-10-08
EP2354225A9 (en) 2012-06-27
KR20110059888A (ko) 2011-06-07
DK2354225T3 (en) 2015-06-29
AU2009297626B2 (en) 2016-01-14
IL211929A0 (en) 2011-06-30
BRPI0919268A8 (pt) 2018-02-06
KR101694559B1 (ko) 2017-01-09
AU2009297626A2 (en) 2011-05-19
EP2354225A4 (en) 2012-03-21

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