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HU0003975D0 - - Google Patents

Info

Publication number
HU0003975D0
HU0003975D0 HU0003975A HU0003975A HU0003975D0 HU 0003975 D0 HU0003975 D0 HU 0003975D0 HU 0003975 A HU0003975 A HU 0003975A HU 0003975 A HU0003975 A HU 0003975A HU 0003975 D0 HU0003975 D0 HU 0003975D0
Authority
HU
Hungary
Prior art keywords
radical
representing
compounds
formula
image
Prior art date
Application number
HU0003975A
Other languages
English (en)
Other versions
HU221978B1 (hu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR9213320A external-priority patent/FR2697523B1/fr
Priority claimed from FR9308109A external-priority patent/FR2707088B1/fr
Application filed filed Critical
Publication of HU0003975D0 publication Critical patent/HU0003975D0/hu
Publication of HU221978B1 publication Critical patent/HU221978B1/hu

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7052—Compounds having saccharide radicals and heterocyclic rings having nitrogen as a ring hetero atom, e.g. nucleosides, nucleotides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epidemiology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
HU0003975A 1992-11-05 1993-11-05 Új eritromicinszármazékok előállítására alkalmazható intermedierek HU221978B1 (hu)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9213320A FR2697523B1 (fr) 1992-11-05 1992-11-05 Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR9308109A FR2707088B1 (fr) 1993-07-02 1993-07-02 Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.

Publications (2)

Publication Number Publication Date
HU0003975D0 true HU0003975D0 (hu) 2000-12-28
HU221978B1 HU221978B1 (hu) 2003-03-28

Family

ID=26229842

Family Applications (3)

Application Number Title Priority Date Filing Date
HU9303148A HU220048B (hu) 1992-11-05 1993-11-05 Új eritromicinszármazékok, eljárás a vegyületek és a vegyületeket tartalmazó gyógyszerkészítmények előállítására
HU0003975A HU221978B1 (hu) 1992-11-05 1993-11-05 Új eritromicinszármazékok előállítására alkalmazható intermedierek
HU0200629D HU222113B1 (hu) 1992-11-05 1993-11-05 Eritromicinszármazékok előálítására alkalmazható amin intermedierek

Family Applications Before (1)

Application Number Title Priority Date Filing Date
HU9303148A HU220048B (hu) 1992-11-05 1993-11-05 Új eritromicinszármazékok, eljárás a vegyületek és a vegyületeket tartalmazó gyógyszerkészítmények előállítására

Family Applications After (1)

Application Number Title Priority Date Filing Date
HU0200629D HU222113B1 (hu) 1992-11-05 1993-11-05 Eritromicinszármazékok előálítására alkalmazható amin intermedierek

Country Status (16)

Country Link
US (2) US5527780A (hu)
EP (1) EP0596802B1 (hu)
JP (2) JP3000022B2 (hu)
KR (1) KR100317149B1 (hu)
CN (1) CN1040876C (hu)
AT (1) ATE135706T1 (hu)
AU (1) AU670329B2 (hu)
BR (1) BR9304481A (hu)
CA (1) CA2102457C (hu)
DE (1) DE69301897T2 (hu)
DK (1) DK0596802T3 (hu)
ES (1) ES2085130T3 (hu)
GR (1) GR3019385T3 (hu)
HU (3) HU220048B (hu)
MA (1) MA23018A1 (hu)
RU (1) RU2126416C1 (hu)

Families Citing this family (86)

* Cited by examiner, † Cited by third party
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FR2718450B1 (fr) * 1994-04-08 1997-01-10 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2719587B1 (fr) * 1994-05-03 1996-07-12 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2727969B1 (fr) * 1994-12-09 1997-01-17 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2732023B1 (fr) * 1995-03-22 1997-04-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2732684B1 (fr) * 1995-04-06 1997-04-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
US5747466A (en) * 1995-11-08 1998-05-05 Abbott Laboratories 3-deoxy-3-descladinose derivatives of erythromycins A and B
FR2742757B1 (fr) * 1995-12-22 1998-01-30 Roussel Uclaf Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2751656B1 (fr) * 1996-07-24 1998-10-16 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
UA51730C2 (uk) * 1996-09-04 2002-12-16 Ебботт Лабораторіз 6-o-заміщені кетоліди з антибактеріальною активністю, спосіб їх одержання (варіанти), фармацевтична композиція та спосіб регулювання бактеріальної інфекції у ссавців
ES2244716T3 (es) * 1996-09-04 2005-12-16 Abbott Laboratories Cetolidos 6-o-sustituidos que tienen actividad antibacteriana.
FR2757168B1 (fr) * 1996-12-12 1999-06-11 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
FR2760017B1 (fr) * 1997-02-27 1999-04-30 Hoechst Marion Roussel Inc Nouveaux derives de l'erytromycine, leur procede de preparation et leur application comme medicaments
US5922683A (en) * 1997-05-29 1999-07-13 Abbott Laboratories Multicyclic erythromycin derivatives
AU7226798A (en) * 1997-06-11 1998-12-30 Pfizer Products Inc. 9-oxime erythromycin derivatives
US5780604A (en) * 1997-09-26 1998-07-14 Abbott Laboratories 11,12-cyclic phosphite or phosphate derivatives of erythromycin and related macrolides
US6034069A (en) * 1997-09-30 2000-03-07 Abbott Laboratories 3-'N-modified 6-O-substituted erythromycin ketolide derivatives having antibacterial activity
AU9649598A (en) * 1997-10-29 1999-05-17 Taisho Pharmaceutical Co., Ltd. Erythromycin a, 11,12-carbamate derivatives
US6046171A (en) * 1997-10-29 2000-04-04 Abbott Laboratories 6,11-bridged erythromycin derivatives
US6124269A (en) * 1997-10-29 2000-09-26 Abbott Laboratories 2-Halo-6-O-substituted ketolide derivatives
WO1999021870A1 (en) * 1997-10-29 1999-05-06 Taisho Pharmaceutical Co., Ltd. Erythromycin a 11, 12-carbamate derivatives
HRP980189B1 (en) * 1998-04-06 2004-04-30 Pliva Pharm & Chem Works Novel 15-membered lactams ketolides
FR2777282B1 (fr) * 1998-04-08 2001-04-20 Hoechst Marion Roussel Inc Nouveaux derives de la 2-fluoro 3-de((2,6-dideoxy 3-c-methyl 3-0-methyl-alpha-l-ribohexopyranosyl) oxyl) 6-o-methyl 3-oxo erythromycine, leur procede de preparation et leur application a la synthese de principes actifs de medicaments
JP4573925B2 (ja) * 1998-07-09 2010-11-04 アベンティス・ファーマ・ソシエテ・アノニム 新規のエリスロマイシン誘導体、その製造方法及びその薬剤としての使用
FR2781484B1 (fr) * 1998-07-21 2001-08-10 Hoechst Marion Roussel Inc Nouveaux derives de la 6-deoxy erythromycine, leur procede de preparation et leur application comme medicaments
ATE298761T1 (de) 1998-09-22 2005-07-15 Pfizer Prod Inc Carbamat- und carbazatketolidantibiotika
FR2785612A1 (fr) * 1998-11-10 2000-05-12 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
CN1376160A (zh) 1998-11-03 2002-10-23 辉瑞产品公司 新的大环内酯抗生素
FR2786188B1 (fr) * 1998-11-24 2002-10-31 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur applicaion comme medicaments
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PT1147121E (pt) 1999-01-27 2004-04-30 Pfizer Prod Inc Antibioticos cetolidos
FR2789392B1 (fr) * 1999-02-04 2001-10-05 Hoechst Marion Roussel Inc Nouveaux derives de l'erythromycine, leur procede de preparation et leur application comme medicaments
US6054435A (en) * 1999-03-19 2000-04-25 Abbott Laboratories 6-O-substituted macrolides having antibacterial activity
US6514944B2 (en) 1999-04-16 2003-02-04 Kosan Biosciences, Inc. Macrolide antiinfective agents
US6939861B2 (en) * 1999-04-16 2005-09-06 Kosan Biosciences, Inc. Amido macrolides
US6451768B1 (en) 1999-04-16 2002-09-17 Kosan Biosciences, Inc. Macrolide antiinfective agents
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US6590083B1 (en) 1999-04-16 2003-07-08 Ortho-Mcneil Pharmaceutical, Inc. Ketolide antibacterials
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US6420535B1 (en) 1999-06-07 2002-07-16 Abbott Laboratories 6-O-carbamate ketolide derivatives
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US6764998B1 (en) 2003-06-18 2004-07-20 Enanta Pharmaceuticals, Inc. 6,11-4C-bicyclic 9a-azalide derivatives
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US6753318B1 (en) * 2002-07-25 2004-06-22 Enanta Pharmaceuticals, Inc. 6,11-4-carbon bridged erythromycin derivatives
US7135573B2 (en) * 2002-05-13 2006-11-14 Enanta Pharmaceuticals, Inc. Processes for the preparation of O-(6-Pyrazol-1-yl-pyridin-3-ylmethyl)-hydroxylamine
US7910558B2 (en) * 2002-05-13 2011-03-22 Enanta Pharmaceuticals, Inc. Bridged macrocyclic compounds and processes for the preparation thereof
US7273853B2 (en) * 2002-05-13 2007-09-25 Enanta Pharmaceuticals, Inc. 6-11 bicyclic ketolide derivatives
US6841664B2 (en) 2002-07-25 2005-01-11 Enanra Pharmaceuticals, Inc. 6,11-4-carbon bridged ketolides
US6878691B2 (en) * 2002-05-13 2005-04-12 Enanta Pharmaceuticals, Inc. 6-11 bicyclic ketolide derivatives
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US7129221B2 (en) * 2002-05-13 2006-10-31 Enanta Pharmaceuticals, Inc. 6,11-bicyclic erythromycin derivatives
US7091196B2 (en) * 2002-09-26 2006-08-15 Rib-X Pharmaceuticals, Inc. Bifunctional heterocyclic compounds and methods of making and using same
HRP20020779A2 (en) 2002-09-27 2005-02-28 Pliva-Istra�iva�ki institut d.o.o. NEW 3-DECLADINOSYL DERIVATIVES OF 9-DEOXO-9-DIHYDRO-9a-AZA-9a-HOMOERYTHROMICIN A 9a, 11-CYCLIC CARBAMATES
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US7414030B2 (en) * 2004-01-07 2008-08-19 Enanta Pharmaceuticals, Inc. 6-11 Bicyclic erythromycin derivatives
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US8273720B2 (en) * 2007-09-17 2012-09-25 Enanta Pharmaceuticals, Inc. 6,11-bicyclolides: bridged biaryl macrolide derivatives
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CN107854477A (zh) * 2008-10-24 2018-03-30 森普拉制药公司 使用含三唑的大环内酯治疗抗性疾病的方法
US9937194B1 (en) 2009-06-12 2018-04-10 Cempra Pharmaceuticals, Inc. Compounds and methods for treating inflammatory diseases
JP5914335B2 (ja) 2009-09-10 2016-05-11 センプラ ファーマシューティカルズ，インコーポレイテッド マラリア、結核、及びｍａｃ病の治療方法
BR112012023950A2 (pt) 2010-03-22 2016-07-05 Cempra Pharmaceuticals Inc formas cristalinas de um macrolídeo, e usos dos mesmos
CN105198944B (zh) 2010-05-20 2018-06-01 森普拉制药公司 制备大环内酯和酮内酯及其中间体的方法
KR20180110181A (ko) * 2010-09-10 2018-10-08 셈프라 파마슈티컬스, 인크. 질환을 치료하기 위한 수소결합 형성 플루오로 케토라이드
DE102010055322A1 (de) * 2010-12-21 2012-06-21 Christian-Albrechts-Universität Zu Kiel Antibakteriell und antimykotisch wirkende Substanzen
NZ700182A (en) 2012-03-27 2017-02-24 Cempra Pharmaceuticals Inc Parenteral formulations for administering macrolide antibiotics
RU2015138796A (ru) 2013-03-14 2017-04-19 Семпра Фармасьютикалс, Инк. Способы и составы для лечения респираторных заболеваний
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Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2936865A1 (de) * 1979-09-12 1981-04-02 Bayer Ag, 5090 Leverkusen Verwendung von pikromycin-derivaten als nutritiva
JPS6229595A (ja) * 1985-07-31 1987-02-07 Toyo Jozo Co Ltd ５−ｏ−マイカミノシル−ナルボノライド誘導体およびその製法
US4742049A (en) * 1986-06-04 1988-05-03 Abbott Laboratories Semisynthetic erythromycin antibiotics
IL99995A (en) * 1990-11-21 1997-11-20 Roussel Uclaf Erythromycin derivatives, their preparation and pharmaceutical compositions containing them
KR0166096B1 (ko) * 1990-11-28 1999-01-15 우에하라 아키라 6-0-메틸에리쓰로마이신 a 유도체
FR2697524B1 (fr) * 1992-11-05 1994-12-23 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.
FR2702480B1 (fr) * 1993-03-09 1995-04-28 Roussel Uclaf Nouveaux dérivés de l'érythromycine, leur procédé de préparation et leur application comme médicaments.

Also Published As

Publication number Publication date
HU220048B (hu) 2001-10-28
CA2102457A1 (fr) 1994-05-06
JPH06220082A (ja) 1994-08-09
JP3000022B2 (ja) 2000-01-17
CN1040876C (zh) 1998-11-25
EP0596802B1 (fr) 1996-03-20
AU5047793A (en) 1994-05-19
GR3019385T3 (en) 1996-06-30
EP0596802A1 (fr) 1994-05-11
KR100317149B1 (ko) 2002-06-20
JP3151188B2 (ja) 2001-04-03
MA23018A1 (fr) 1994-07-01
ES2085130T3 (es) 1996-05-16
DE69301897D1 (de) 1996-04-25
CN1090581A (zh) 1994-08-10
US5614614A (en) 1997-03-25
KR940011474A (ko) 1994-06-21
ATE135706T1 (de) 1996-04-15
HU222113B1 (hu) 2003-04-28
DE69301897T2 (de) 1996-11-07
DK0596802T3 (da) 1996-06-03
BR9304481A (pt) 1994-06-21
HU221978B1 (hu) 2003-03-28
CA2102457C (fr) 2002-01-22
US5527780A (en) 1996-06-18
HUT66446A (en) 1994-11-28
JPH11180994A (ja) 1999-07-06
AU670329B2 (en) 1996-07-11
RU2126416C1 (ru) 1999-02-20

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HFG4 Patent granted, date of granting

Effective date: 20030107