HRP20100250T1 - Heterociklički kondenzirani spojevi upotrebljivi kao antidiuretski agensi - Google Patents
Heterociklički kondenzirani spojevi upotrebljivi kao antidiuretski agensi Download PDFInfo
- Publication number
- HRP20100250T1 HRP20100250T1 HR20100250T HRP20100250T HRP20100250T1 HR P20100250 T1 HRP20100250 T1 HR P20100250T1 HR 20100250 T HR20100250 T HR 20100250T HR P20100250 T HRP20100250 T HR P20100250T HR P20100250 T1 HRP20100250 T1 HR P20100250T1
- Authority
- HR
- Croatia
- Prior art keywords
- oxo
- carbonyl
- dihydro
- alkyl
- methyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/12—Antidiuretics, e.g. drugs for diabetes insipidus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US60289004P | 2004-08-20 | 2004-08-20 | |
| EP04104006A EP1627876A1 (en) | 2004-08-20 | 2004-08-20 | Heterocyclic condensed compounds useful as antidiuretic agents |
| PCT/EP2005/054081 WO2006018443A1 (en) | 2004-08-20 | 2005-08-18 | Heterocyclic condensed compounds useful as antidiuretic agents |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| HRP20100250T1 true HRP20100250T1 (hr) | 2010-06-30 |
Family
ID=34929464
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| HR20100250T HRP20100250T1 (hr) | 2004-08-20 | 2005-08-18 | Heterociklički kondenzirani spojevi upotrebljivi kao antidiuretski agensi |
Country Status (21)
| Country | Link |
|---|---|
| US (1) | US8063038B2 (da) |
| EP (2) | EP1627876A1 (da) |
| JP (1) | JP4705105B2 (da) |
| KR (1) | KR100877336B1 (da) |
| CN (1) | CN1968947A (da) |
| AT (1) | ATE457026T1 (da) |
| AU (1) | AU2005273875B2 (da) |
| CA (1) | CA2567782A1 (da) |
| CY (1) | CY1110619T1 (da) |
| DE (1) | DE602005019241D1 (da) |
| DK (1) | DK1778677T3 (da) |
| ES (1) | ES2339786T3 (da) |
| HR (1) | HRP20100250T1 (da) |
| IL (1) | IL178839A0 (da) |
| MX (1) | MX2007001861A (da) |
| NO (1) | NO20071476L (da) |
| PL (1) | PL1778677T3 (da) |
| PT (1) | PT1778677E (da) |
| RU (1) | RU2359969C2 (da) |
| SI (1) | SI1778677T1 (da) |
| WO (1) | WO2006018443A1 (da) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB0000079D0 (en) * | 2000-01-05 | 2000-02-23 | Ferring Bv | Novel antidiuretic agents |
| EP1632494A1 (en) | 2004-08-24 | 2006-03-08 | Ferring B.V. | Vasopressin v1a antagonists |
| US9096546B2 (en) | 2007-05-10 | 2015-08-04 | Albany Molecular Research, Inc. | Aryl- and heteroaryl-substituted tetrahydrobenzo-1,4-diazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin |
| US9029408B2 (en) | 2008-06-16 | 2015-05-12 | Gtx, Inc. | Compounds for treatment of cancer |
| US9447049B2 (en) | 2010-03-01 | 2016-09-20 | University Of Tennessee Research Foundation | Compounds for treatment of cancer |
| EP3289876B1 (en) | 2008-06-16 | 2022-07-20 | University of Tennessee Research Foundation | Compounds for treatment of cancer |
| CN102089289A (zh) | 2008-07-16 | 2011-06-08 | 弗·哈夫曼-拉罗切有限公司 | 用于治疗心血管疾病的新的杂环基化合物 |
| WO2011005842A1 (en) | 2009-07-09 | 2011-01-13 | Gilead Sciences, Inc. | Anti-rsv compounds |
| JP2011057661A (ja) * | 2009-08-14 | 2011-03-24 | Bayer Cropscience Ag | 殺虫性カルボキサミド類 |
| RU2581367C2 (ru) | 2010-03-01 | 2016-04-20 | Джи Ти Икс, ИНК. | Соединения для лечения рака |
| US9119878B2 (en) | 2010-07-08 | 2015-09-01 | Wellesley Pharmaceuticals, Llc | Extended-release formulation for reducing the frequency of urination and method of use thereof |
| EP2612663A1 (en) * | 2012-01-04 | 2013-07-10 | Wellesley Pharmaceuticals, LLC | Extended-release formulation for reducing the frequency of urination and method of use thereof |
| EP2612662B1 (en) * | 2012-01-04 | 2020-03-04 | Wellesley Pharmaceuticals, LLC | Delayed-release formulation for reducing the frequency of urination and method of use thereof |
| JP2015506359A (ja) * | 2012-01-04 | 2015-03-02 | ウェルズリー ファーマスーティカルズ、エルエルシー | 排尿頻度を減少させるための遅延放出製剤およびその使用の方法 |
| MX2014008283A (es) * | 2012-01-04 | 2015-03-03 | Wellesley Pharmaceutical Llc | Formulacion de liberacion prolongada para reducir la frecuencia de orinar y metodos de uso de esta. |
| NZ714288A (en) * | 2012-03-19 | 2016-12-23 | Wellesley Pharmaceuticals Llc | Extended-release formulation for reducing the frequency of urination and method of use thereof |
| US10596127B2 (en) | 2013-03-14 | 2020-03-24 | Wellesley Pharmaceuticals, Llc | Composition for reducing the frequency of urination, method of making and use thereof |
| CN105189447B (zh) * | 2013-06-25 | 2017-12-05 | 组合化学工业株式会社 | 制造硝基苯化合物的方法 |
| CN106810508B (zh) * | 2017-01-05 | 2019-12-10 | 浙江农林大学暨阳学院 | 一种铁催化多组分反应合成苯并[1,4]-氧氮杂卓化合物的方法 |
| WO2019003433A1 (ja) * | 2017-06-30 | 2019-01-03 | 大塚製薬株式会社 | ベンゾアゼピン誘導体 |
| CN114853728B (zh) * | 2022-05-07 | 2023-11-07 | 四川制药制剂有限公司 | 一种富马酸伏诺拉生片及其制备方法 |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL104853A (en) * | 1992-02-27 | 1997-11-20 | Yamanouchi Pharma Co Ltd | Benzodiazepine derivatives, their preparation and pharmaceutical compositions containing them |
| US5512563A (en) * | 1993-07-29 | 1996-04-30 | American Cyanamid Company | Tricyclic benzazepine vasopressin antagonists |
| ES2229525T3 (es) * | 1997-07-30 | 2005-04-16 | Wyeth | Agonistas triciclicos de la vasopresina. |
| WO1999006403A1 (en) * | 1997-07-30 | 1999-02-11 | American Home Products Corporation | Tricyclic vasopressin agonists |
| GB0015601D0 (en) * | 2000-06-26 | 2000-08-16 | Ferring Bv | Novel antidiuretic agents |
-
2004
- 2004-08-20 EP EP04104006A patent/EP1627876A1/en not_active Withdrawn
-
2005
- 2005-08-18 SI SI200530930T patent/SI1778677T1/sl unknown
- 2005-08-18 ES ES05781746T patent/ES2339786T3/es active Active
- 2005-08-18 EP EP05781746A patent/EP1778677B1/en active Active
- 2005-08-18 CN CNA2005800192975A patent/CN1968947A/zh active Pending
- 2005-08-18 CA CA002567782A patent/CA2567782A1/en not_active Abandoned
- 2005-08-18 US US11/660,207 patent/US8063038B2/en not_active Expired - Fee Related
- 2005-08-18 DE DE602005019241T patent/DE602005019241D1/de active Active
- 2005-08-18 MX MX2007001861A patent/MX2007001861A/es active IP Right Grant
- 2005-08-18 AU AU2005273875A patent/AU2005273875B2/en not_active Ceased
- 2005-08-18 PT PT05781746T patent/PT1778677E/pt unknown
- 2005-08-18 PL PL05781746T patent/PL1778677T3/pl unknown
- 2005-08-18 DK DK05781746.2T patent/DK1778677T3/da active
- 2005-08-18 WO PCT/EP2005/054081 patent/WO2006018443A1/en active Application Filing
- 2005-08-18 HR HR20100250T patent/HRP20100250T1/hr unknown
- 2005-08-18 JP JP2007526462A patent/JP4705105B2/ja not_active Expired - Fee Related
- 2005-08-18 AT AT05781746T patent/ATE457026T1/de active
- 2005-08-18 KR KR1020077002387A patent/KR100877336B1/ko not_active Expired - Fee Related
- 2005-08-18 RU RU2007101237/04A patent/RU2359969C2/ru not_active IP Right Cessation
-
2006
- 2006-10-24 IL IL178839A patent/IL178839A0/en unknown
-
2007
- 2007-03-19 NO NO20071476A patent/NO20071476L/no not_active Application Discontinuation
-
2010
- 2010-04-26 CY CY20101100370T patent/CY1110619T1/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO20071476L (no) | 2007-03-19 |
| HK1100290A1 (en) | 2007-09-14 |
| JP2008509972A (ja) | 2008-04-03 |
| KR20070027761A (ko) | 2007-03-09 |
| ES2339786T3 (es) | 2010-05-25 |
| AU2005273875A1 (en) | 2006-02-23 |
| ATE457026T1 (de) | 2010-02-15 |
| US20080234250A1 (en) | 2008-09-25 |
| RU2359969C2 (ru) | 2009-06-27 |
| AU2005273875B2 (en) | 2009-08-27 |
| EP1627876A1 (en) | 2006-02-22 |
| PL1778677T3 (pl) | 2010-07-30 |
| PT1778677E (pt) | 2010-03-17 |
| KR100877336B1 (ko) | 2009-01-07 |
| RU2007101237A (ru) | 2008-09-27 |
| SI1778677T1 (sl) | 2010-09-30 |
| IL178839A0 (en) | 2007-03-08 |
| MX2007001861A (es) | 2007-04-24 |
| EP1778677A1 (en) | 2007-05-02 |
| CA2567782A1 (en) | 2006-02-23 |
| CY1110619T1 (el) | 2015-04-29 |
| CN1968947A (zh) | 2007-05-23 |
| EP1778677B1 (en) | 2010-02-03 |
| DK1778677T3 (da) | 2010-04-19 |
| US8063038B2 (en) | 2011-11-22 |
| WO2006018443A1 (en) | 2006-02-23 |
| DE602005019241D1 (de) | 2010-03-25 |
| JP4705105B2 (ja) | 2011-06-22 |
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