GB901719A - Process for the production of hyodesoxycholic acid - Google Patents
Process for the production of hyodesoxycholic acidInfo
- Publication number
- GB901719A GB901719A GB1382361A GB1382361A GB901719A GB 901719 A GB901719 A GB 901719A GB 1382361 A GB1382361 A GB 1382361A GB 1382361 A GB1382361 A GB 1382361A GB 901719 A GB901719 A GB 901719A
- Authority
- GB
- United Kingdom
- Prior art keywords
- hyodesoxycholic acid
- mixture
- saponifying
- naphthylamine
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J75/00—Processes for the preparation of steroids in general
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
Abstract
Hyodesoxycholic acid is obtained from crude bile acid mixtures by esterifying said mixture, dissolving the resultant ester mixture in an alkyl ether containing 4-8 carbon atoms, adding to the ethereal solution an aromatic amine of the general formula: <FORM:0901719/IV (b)/1> in which X1, X2 and X3 are hydrogen atoms or alkyl radicals and X1 and X2 can also be a fused benzene ring, separating off the hyodesoxycholic acid ester-amine adduct which thereby precipitates and decomposing it into its components, and saponifying the thus obtained hyodesoxycholic acid ester. As the aromatic amines there may be used aniline, a toluidine, a xylidine or one of the corresponding ethyl or propyl homologues, b -naphthylamine or a 3-alkyl-b -naphthylamine. The crude starting mixture is obtained by saponifying pig bile.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DER28041A DE1123319B (en) | 1960-05-27 | 1960-05-27 | Process for the isolation of hyodeoxycholic acid from crude bile acid mixtures |
| DER28239A DE1127896B (en) | 1960-07-01 | 1960-07-01 | Process for the isolation of hyodeoxycholic acid from crude bile acid mixtures |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB901719A true GB901719A (en) | 1962-07-25 |
Family
ID=25991369
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB1382361A Expired GB901719A (en) | 1960-05-27 | 1961-04-17 | Process for the production of hyodesoxycholic acid |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB901719A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103012534A (en) * | 2012-12-19 | 2013-04-03 | 四川大熊生物技术有限公司 | Method for extracting hyodeoxycholic acid from pig bile |
-
1961
- 1961-04-17 GB GB1382361A patent/GB901719A/en not_active Expired
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103012534A (en) * | 2012-12-19 | 2013-04-03 | 四川大熊生物技术有限公司 | Method for extracting hyodeoxycholic acid from pig bile |
| CN103012534B (en) * | 2012-12-19 | 2015-03-18 | 四川大熊生物技术有限公司 | Method for extracting hyodeoxycholic acid from pig bile |
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