GB706791A - Improved manufacture of aqueous dispersions and jellies of steroidic and terpenic esters - Google Patents
Improved manufacture of aqueous dispersions and jellies of steroidic and terpenic estersInfo
- Publication number
- GB706791A GB706791A GB14047/51A GB1404751A GB706791A GB 706791 A GB706791 A GB 706791A GB 14047/51 A GB14047/51 A GB 14047/51A GB 1404751 A GB1404751 A GB 1404751A GB 706791 A GB706791 A GB 706791A
- Authority
- GB
- United Kingdom
- Prior art keywords
- steroidic
- vitamin
- absolute
- treated
- esters
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/59—Compounds containing 9, 10- seco- cyclopenta[a]hydrophenanthrene ring systems
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Steroid Compounds (AREA)
Abstract
Halogenbetainilic esters of steroidic or terpinic alcohols are made by the two following steps: (1) an absolute ethereal solution of the alcohol is treated with equimolecular quantities of a halide of a halogen acetic acid and pyridine; and (2) the product obtained in absolute ethereal solution or in other inactive solvent and at a temperature of -5 DEG C. is treated with a tertiary aliphatic amine, such as trimethylamine. The product is dispersed in water to form a solution or jelly for use as medicine. The alcohols specified are cholesterine, testosterone, folliculine, dehydrofolliculine, corticosterone, desoxycorticosterone, vitamin D, ergosterine, Vitamin A or mixtures thereof.ALSO:Halogenbetainilic esters of steroidic or terpinic alcohols are made by the two following steps: - (1) an absolute ethereal solution of the alcohol is treated with equimolecular quantities of a halide of a halogen acetic acid and pyridine and (2) the product obtained in absolute ethereal solution or in other inactive solvent and at a temperature of 5 DEG C is treated with a tertiary aliphatic amine, such as trimethylamine. The product is dispersed in water to form a solution or jelly for use as a medicine. The alcohols specified are cholesterine, testosterone, folliculine, dehydrofolliculine, corticosterone, desoxycorticosterone, vitamin D, ergosterine, vitamin A or mixtures thereof.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IT706791X | 1950-06-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| GB706791A true GB706791A (en) | 1954-04-07 |
Family
ID=11314215
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| GB14047/51A Expired GB706791A (en) | 1950-06-13 | 1951-06-13 | Improved manufacture of aqueous dispersions and jellies of steroidic and terpenic esters |
Country Status (1)
| Country | Link |
|---|---|
| GB (1) | GB706791A (en) |
-
1951
- 1951-06-13 GB GB14047/51A patent/GB706791A/en not_active Expired
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