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GB612130A - Manufacture of 11-dehydrocorticosterone and derivatives thereof - Google Patents

Manufacture of 11-dehydrocorticosterone and derivatives thereof

Info

Publication number
GB612130A
GB612130A GB1116446A GB1116446A GB612130A GB 612130 A GB612130 A GB 612130A GB 1116446 A GB1116446 A GB 1116446A GB 1116446 A GB1116446 A GB 1116446A GB 612130 A GB612130 A GB 612130A
Authority
GB
United Kingdom
Prior art keywords
ketone
group
free
hydroxyl group
dehydrocorticosterone
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
GB1116446A
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to GB1116446A priority Critical patent/GB612130A/en
Publication of GB612130A publication Critical patent/GB612130A/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)

Abstract

11-Dehydrocorticosterone or its derivatives are made by the process of the parent Specification by reacting a D 5 : 6-3-oxy-11-keto-aetiocholenic acid, of which the hydroxyl group is protected, to react with diazomethane, setting free the protected hydroxyl group in the 3-position in the resulting diazo-ketone or halogen ketone, converting the diazo-ketone group or halogen-ketone group before or after oxidation of the free 3-hydroxyl group into a free or esterified ketol group, and if desired, treating the product with a hydrolysing agent and/or an esterifying agent. A detailed example is given. Specification 612,129 is referred to.
GB1116446A 1946-04-11 1946-04-11 Manufacture of 11-dehydrocorticosterone and derivatives thereof Expired GB612130A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
GB1116446A GB612130A (en) 1946-04-11 1946-04-11 Manufacture of 11-dehydrocorticosterone and derivatives thereof

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB1116446A GB612130A (en) 1946-04-11 1946-04-11 Manufacture of 11-dehydrocorticosterone and derivatives thereof

Publications (1)

Publication Number Publication Date
GB612130A true GB612130A (en) 1948-11-09

Family

ID=9981194

Family Applications (1)

Application Number Title Priority Date Filing Date
GB1116446A Expired GB612130A (en) 1946-04-11 1946-04-11 Manufacture of 11-dehydrocorticosterone and derivatives thereof

Country Status (1)

Country Link
GB (1) GB612130A (en)

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