GB2128615B - Platinum 1,3-propane diamine complexes - Google Patents

Platinum 1,3-propane diamine complexes

Info

Publication number: GB2128615B
Authority: GB; United Kingdom
Prior art keywords: platinum; propane diamine; diamine complexes; complexes; propane
Prior art date: 1982-10-21
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired

Application number

GB08328084A

Other languages

English (en)

Other versions

GB8328084D0 (en

GB2128615A (en

Inventor

Francois Verbeek

Jan Berg

Eric Jan Bulten

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO

Original Assignee

Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1982-10-21

Filing date

1983-10-20

Publication date

1986-07-16

1983-10-20 Application filed by Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO filed Critical Nederlandse Organisatie voor Toegepast Natuurwetenschappelijk Onderzoek TNO

1983-11-23 Publication of GB8328084D0 publication Critical patent/GB8328084D0/en

1984-05-02 Publication of GB2128615A publication Critical patent/GB2128615A/en

1986-07-16 Application granted granted Critical

1986-07-16 Publication of GB2128615B publication Critical patent/GB2128615B/en

Status Expired legal-status Critical Current

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F15/00—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table
- C07F15/0006—Compounds containing elements of Groups 8, 9, 10 or 18 of the Periodic Table compounds of the platinum group
- C07F15/0086—Platinum compounds
- C07F15/0093—Platinum compounds without a metal-carbon linkage
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/28—Compounds containing heavy metals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
General Health & Medical Sciences (AREA)
Veterinary Medicine (AREA)
Public Health (AREA)
Pharmacology & Pharmacy (AREA)
Medicinal Chemistry (AREA)
Animal Behavior & Ethology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Epidemiology (AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

GB08328084A 1982-10-21 1983-10-20 Platinum 1,3-propane diamine complexes Expired GB2128615B (en)

Applications Claiming Priority (1)

Application Number	Priority Date	Filing Date	Title
NL8204067A NL8204067A (nl)	1982-10-21	1982-10-21	Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een geneesmiddel met toepassing van een dergelijk platinadiaminecomplex voor de behandeling van kanker, alsmede aldus verkregen gevormd geneesmiddel.

Publications (3)

Publication Number	Publication Date
GB8328084D0 GB8328084D0 (en)	1983-11-23
GB2128615A GB2128615A (en)	1984-05-02
GB2128615B true GB2128615B (en)	1986-07-16

Family

ID=19840444

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
GB08328084A Expired GB2128615B (en)	1982-10-21	1983-10-20	Platinum 1,3-propane diamine complexes

Country Status (28)

Country	Link
JP (1)	JPS5993091A (xx)
KR (1)	KR910002536B1 (xx)
AT (1)	AT390610B (xx)
AU (1)	AU562964B2 (xx)
BE (1)	BE898058A (xx)
CA (1)	CA1229618A (xx)
CH (1)	CH658244A5 (xx)
CS (1)	CS242888B2 (xx)
DD (1)	DD217522A5 (xx)
DE (1)	DE3337333A1 (xx)
DK (2)	DK483083A (xx)
ES (1)	ES526670A0 (xx)
FI (1)	FI76351C (xx)
FR (1)	FR2534907B1 (xx)
GB (1)	GB2128615B (xx)
GR (1)	GR79652B (xx)
HU (1)	HU188035B (xx)
IE (1)	IE56124B1 (xx)
IT (1)	IT1169858B (xx)
LU (1)	LU85054A1 (xx)
NL (1)	NL8204067A (xx)
NO (1)	NO171276C (xx)
NZ (1)	NZ206018A (xx)
PH (1)	PH24077A (xx)
PT (1)	PT77542B (xx)
SE (1)	SE8305783L (xx)
YU (1)	YU43554B (xx)
ZA (1)	ZA837857B (xx)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20150299237A1 (en) *	2012-10-29	2015-10-22	Southeast University	Anti-tumor bivalent platinum complex and preparation method for complex and ligand of complex

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4786725A (en) *	1982-06-28	1988-11-22	Engelhard Corporation	Solubilized platinum (II) complexes
US4661516A (en) *	1983-06-20	1987-04-28	Research Corporation	Diaminocyclohexane platinum complexes
US4758588A (en) *	1983-06-20	1988-07-19	Research Corporation Technologies	Diaminocyclohexane platinum complexes
EP0169645A1 (en) *	1984-06-27	1986-01-29	Johnson Matthey Public Limited Company	Platinum co-ordination compounds
DE3432320A1 (de) *	1984-09-03	1986-03-13	Behringwerke Ag, 3550 Marburg	Cis-platin-komplexe mit einem pentaerythritderivat als liganden, verfahren zu ihrer herstellung und diese verbindungen enthaltendes pharmazeutisches mittel
HU193809B (en) *	1984-09-12	1987-12-28	Chugai Pharmaceutical Co Ltd	Process for producing new platinum complexes
US4737589A (en) *	1985-08-27	1988-04-12	Nippon Kayaku Kabushiki Kaisha	Platinum Complexes
US4760157A (en) *	1986-01-31	1988-07-26	American Cyanamid Company	(2,2,-bis(aminomethyl)-1,3-propanediol-N,N')platinum complexes
US4880790A (en) *	1986-01-31	1989-11-14	American Cyanamid Company	(Gem-heterocyclodimethanamine-N,N')platinum complexes
DE3630497A1 (de) *	1986-09-08	1988-03-10	Behringwerke Ag	Cis-platin-komplexe, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische mittel
ATE53217T1 (de) *	1986-10-03	1990-06-15	Asta Pharma Ag	Diamin-platin (ii)-komplexverbindungen mit einem hydroxylierten 2-phenyl-indolring.
JPS63203692A (ja) *	1987-02-19	1988-08-23	Nippon Kayaku Co Ltd	新規白金錯体
AT390065B (de) *	1987-10-08	1990-03-12	Behringwerke Ag	Cis-platin-komplexe, verfahren zu ihrer herstellung und diese verbindungen enthaltende pharmazeutische mittel
NL8802149A (nl) *	1988-08-31	1990-03-16	Tno	Platina-(iv)diaminecomplex, werkwijze voor het bereiden van deze verbinding, preparaat met anti-tumor werking, dat ten minste een platinaverbinding bevat, alsmede gevormde preparaten met anti-tumor werking.
NL8802150A (nl) *	1988-08-31	1990-03-16	Tno	Platina-(ii)-diaminecomplex, werkwijze voor het bereiden van deze verbinding, preparaat met anti-tumor werking, dat deze verbinding bevat, alsmede gevormde preparaten met anti-tumor werking.

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US4115418A (en) *	1976-09-02	1978-09-19	Government Of The United States Of America	1,2-diaminocyclohexane platinum (ii) complexes having antineoplastic activity
US4206226A (en) *	1977-08-29	1980-06-03	The United States Of America As Represented By The Department Of Health, Education And Welfare	Use of 4-carboxy-phthalato-(1,2-diaminocyclohexane)-platinum(II) and alkali metal salts thereof in alleviating L1210 murine leukemia
NL189358C (nl) *	1978-07-06	1993-03-16	Tno	Werkwijze voor het bereiden van een geneesmiddel voor de behandeling van kanker, alsmede een van een 1,3-alkaandiamine afgeleid platina-diamminecomplex.
NL7807334A (nl) *	1978-07-06	1980-01-08	Tno	Platina-diaminecomplexen, werkwijze voor het bereiden daarvan, werkwijze voor het bereiden van een genees- middel met toepassing van een dergelijk platina-dia- minecomplex voor de behandeling van kanker, alsmede al- dus verkregen gevormd geneesmiddel.
US4322362A (en) *	1980-07-28	1982-03-30	Bristol-Myers Company	Salts of 2-hydroxymalonate platinum complexes
NZ197104A (en) *	1980-05-27	1984-05-31	Bristol Myers Co	Soluble ammonium and sodium salts of 2-hydroxymalonato platinum ii derivatives

1982
- 1982-10-21 NL NL8204067A patent/NL8204067A/nl not_active Application Discontinuation
1983
- 1983-10-13 DE DE19833337333 patent/DE3337333A1/de not_active Ceased
- 1983-10-18 AU AU20275/83A patent/AU562964B2/en not_active Ceased
- 1983-10-19 CA CA000439308A patent/CA1229618A/en not_active Expired
- 1983-10-19 IT IT23359/83A patent/IT1169858B/it active
- 1983-10-20 YU YU2107/83A patent/YU43554B/xx unknown
- 1983-10-20 DK DK483083A patent/DK483083A/da not_active Application Discontinuation
- 1983-10-20 AT AT0373083A patent/AT390610B/de not_active IP Right Cessation
- 1983-10-20 IE IE2459/83A patent/IE56124B1/en not_active IP Right Cessation
- 1983-10-20 GR GR72754A patent/GR79652B/el unknown
- 1983-10-20 SE SE8305783A patent/SE8305783L/ not_active Application Discontinuation
- 1983-10-20 GB GB08328084A patent/GB2128615B/en not_active Expired
- 1983-10-20 DD DD83255826A patent/DD217522A5/de not_active IP Right Cessation
- 1983-10-20 NZ NZ206018A patent/NZ206018A/en unknown
- 1983-10-20 FR FR8316715A patent/FR2534907B1/fr not_active Expired
- 1983-10-20 PT PT77542A patent/PT77542B/pt unknown
- 1983-10-20 FI FI833842A patent/FI76351C/fi not_active IP Right Cessation
- 1983-10-20 LU LU85054A patent/LU85054A1/xx unknown
- 1983-10-20 CH CH5718/83A patent/CH658244A5/de not_active IP Right Cessation
- 1983-10-20 HU HU833623A patent/HU188035B/hu not_active IP Right Cessation
- 1983-10-20 NO NO833825A patent/NO171276C/no unknown
- 1983-10-21 JP JP58196286A patent/JPS5993091A/ja active Granted
- 1983-10-21 PH PH29726A patent/PH24077A/en unknown
- 1983-10-21 KR KR1019830004987A patent/KR910002536B1/ko not_active IP Right Cessation
- 1983-10-21 ES ES526670A patent/ES526670A0/es active Granted
- 1983-10-21 BE BE0/211755A patent/BE898058A/nl not_active IP Right Cessation
- 1983-10-21 CS CS837752A patent/CS242888B2/cs unknown
- 1983-10-21 ZA ZA837857A patent/ZA837857B/xx unknown
1992
- 1992-06-09 DK DK075592A patent/DK75592A/da not_active Application Discontinuation

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US20150299237A1 (en) *	2012-10-29	2015-10-22	Southeast University	Anti-tumor bivalent platinum complex and preparation method for complex and ligand of complex
US9227991B2 (en) *	2012-10-29	2016-01-05	Southeast University	Anti-tumor bivalent platinum complex and preparation method for complex and ligand of complex

Also Published As

Publication number	Publication date
FR2534907A1 (fr)	1984-04-27
IE832459L (en)	1984-04-21
IE56124B1 (en)	1991-04-24
GB8328084D0 (en)	1983-11-23
LU85054A1 (xx)	1984-03-22
NL8204067A (nl)	1984-05-16
JPS5993091A (ja)	1984-05-29
NO171276C (no)	1993-02-17
DD217522A5 (de)	1985-01-16
AU562964B2 (en)	1987-06-25
GR79652B (xx)	1984-10-31
FR2534907B1 (fr)	1988-08-19
SE8305783D0 (sv)	1983-10-20
DE3337333A1 (de)	1984-04-26
SE8305783L (sv)	1984-04-22
NZ206018A (en)	1986-02-21
ATA373083A (de)	1989-11-15
FI833842A0 (fi)	1983-10-20
FI833842A (fi)	1984-04-22
ES8406498A1 (es)	1984-07-01
PT77542A (en)	1983-11-01
IT1169858B (it)	1987-06-03
DK75592D0 (da)	1992-06-09
IT8323359A0 (it)	1983-10-19
HU188035B (en)	1986-03-28
PH24077A (en)	1990-03-05
FI76351B (fi)	1988-06-30
JPH0244479B2 (xx)	1990-10-04
CA1229618A (en)	1987-11-24
KR840006492A (ko)	1984-11-30
KR910002536B1 (ko)	1991-04-23
FI76351C (fi)	1988-10-10
ZA837857B (en)	1984-06-27
ES526670A0 (es)	1984-07-01
CH658244A5 (de)	1986-10-31
YU43554B (en)	1989-08-31
PT77542B (en)	1986-02-12
YU210783A (en)	1986-08-31
NO171276B (no)	1992-11-09
AT390610B (de)	1990-06-11
DK483083D0 (da)	1983-10-20
NO833825L (no)	1984-04-24
CS775283A2 (en)	1985-08-15
DK75592A (da)	1992-06-09
DK483083A (da)	1984-04-22
CS242888B2 (en)	1986-05-15
AU2027583A (en)	1984-05-03
GB2128615A (en)	1984-05-02
BE898058A (nl)	1984-04-24

Publication	Publication Date	Title
PH21308A (en)	1987-09-28	3-keto-19-nor-/4,9-steroids
GB2128615B (en)	1986-07-16	Platinum 1,3-propane diamine complexes
ZA847535B (en)	1985-05-29	1,3-diaryl-5-methylene-perhydropyrimidin-2-ones
CS997683A2 (en)	1985-08-15	Zpusob vyroby derivatu 1,4:3,6-dianhydrohexitolu
GB2127807B (en)	1987-02-25	2,5-piperazinediones
CS604984A2 (en)	1985-08-15	Zpusob tepelneho stepeni 1,2 dichloretanu
GB2160525B (en)	1987-08-26	8,10-dideazaminopterins
GB2140007B (en)	1986-04-09	1,8-dihydroxy-10-acyl-9-anthrones
CS620984A2 (en)	1985-09-17	Zpusob izolace 2-naftylamin-3,6,8-trisulfonove kyseliny
GB8301383D0 (en)	1983-02-23	3,3-dialkyl-and 3,3-alkylene-indoline derivatives
CS912983A2 (en)	1985-06-13	Zpusob vyroby l,2 dichlorethanu
GB2148887B (en)	1987-02-25	1,3-7 oxazino4,3-a-7
CS980483A2 (en)	1985-06-13	Zpusob vyroby 1,2 dichlorethanu
CS546582A1 (en)	1984-02-13	Zpusob pripravy farmakologicky ucinnych derivatu 1,4 diaminoantrachinonu
CS648483A1 (en)	1984-05-14	Sposob vyroby 2,2 azobisizobutyronitrilu
CS760383A1 (en)	1985-06-13	Sposob vyroby 1,1 azobisformamidu
CS378583A1 (en)	1984-11-19	Sposob vyroby 1,1 azobisformamidu
ZA832310B (en)	1983-12-28	1,3,5-triacrylylhexahydro-s-triazine derivatives
CS1024484A2 (en)	1988-07-15	Zpusob vyroby 3,4,5 trimethoxybenzonitrilu
CS623382A1 (en)	1984-01-16	Zpusob chemicke rafinace technickeho 2,6 xylenolu
CS592584A1 (en)	1985-06-13	Zpusob rafinace 2,6 xylenolu
CS812882A1 (en)	1984-05-14	Zpusob vyroby derivatu 2,5 dioxopiperazinu
CS765482A1 (en)	1984-01-16	Zpusob vyroby derivatu 2,5 piperazindionu
CS686884A2 (en)	1985-06-13	Zpusob vyroby 1,2 dichlorethanu
CS581182A1 (en)	1984-02-13	Zpusob rafinace technickeho 2,6 xylenolu

Legal Events

Date	Code	Title	Description
1994-06-15	PCNP	Patent ceased through non-payment of renewal fee	Effective date: 19931020