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FIC20200037I1 - Otsanimodi tai sen farmaseuttisesti hyväksyttävä suola, erityisesti otsanimodihydrokloridi - Google Patents

Otsanimodi tai sen farmaseuttisesti hyväksyttävä suola, erityisesti otsanimodihydrokloridi

Info

Publication number
FIC20200037I1
FIC20200037I1 FIC20200037C FIC20200037C FIC20200037I1 FI C20200037 I1 FIC20200037 I1 FI C20200037I1 FI C20200037 C FIC20200037 C FI C20200037C FI C20200037 C FIC20200037 C FI C20200037C FI C20200037 I1 FIC20200037 I1 FI C20200037I1
Authority
FI
Finland
Prior art keywords
otzanimod
dihydrochloride
pharmaceutically acceptable
acceptable salt
salt
Prior art date
Application number
FIC20200037C
Other languages
English (en)
Original Assignee
The Scripps Research Institute
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Scripps Research Institute filed Critical The Scripps Research Institute
Publication of FIC20200037I1 publication Critical patent/FIC20200037I1/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4245—Oxadiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D271/00—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms
    • C07D271/02—Heterocyclic compounds containing five-membered rings having two nitrogen atoms and one oxygen atom as the only ring hetero atoms not condensed with other rings
    • C07D271/06—1,2,4-Oxadiazoles; Hydrogenated 1,2,4-oxadiazoles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Transplantation (AREA)
  • Neurology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FIC20200037C 2008-05-14 2020-09-24 Otsanimodi tai sen farmaseuttisesti hyväksyttävä suola, erityisesti otsanimodihydrokloridi FIC20200037I1 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US12760308P 2008-05-14 2008-05-14
US12/465,767 US8796318B2 (en) 2008-05-14 2009-05-14 Modulators of sphingosine phosphate receptors

Publications (1)

Publication Number Publication Date
FIC20200037I1 true FIC20200037I1 (fi) 2020-09-24

Family

ID=41416994

Family Applications (2)

Application Number Title Priority Date Filing Date
FIEP09762826.7T FI2291080T5 (fi) 2008-05-14 2009-05-14 Uusia sfingosiinifosfaattireseptorimodulaattoreita
FIC20200037C FIC20200037I1 (fi) 2008-05-14 2020-09-24 Otsanimodi tai sen farmaseuttisesti hyväksyttävä suola, erityisesti otsanimodihydrokloridi

Family Applications Before (1)

Application Number Title Priority Date Filing Date
FIEP09762826.7T FI2291080T5 (fi) 2008-05-14 2009-05-14 Uusia sfingosiinifosfaattireseptorimodulaattoreita

Country Status (20)

Country Link
US (8) US8796318B2 (fi)
EP (3) EP3782991A1 (fi)
JP (2) JP5837417B2 (fi)
AU (2) AU2009258242B2 (fi)
CY (2) CY1123338T1 (fi)
DK (1) DK2291080T3 (fi)
EA (1) EA021672B1 (fi)
ES (2) ES2549761T3 (fi)
FI (2) FI2291080T5 (fi)
HR (1) HRP20150982T1 (fi)
HU (2) HUE025984T2 (fi)
LT (1) LTC2291080I2 (fi)
MY (2) MY172105A (fi)
NL (1) NL301065I2 (fi)
NO (1) NO2020034I1 (fi)
NZ (1) NZ589617A (fi)
PL (2) PL2291080T3 (fi)
PT (2) PT2913326T (fi)
SI (1) SI2291080T1 (fi)
WO (1) WO2009151529A1 (fi)

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CY2020033I1 (el) 2020-11-25
ES2813368T3 (es) 2021-03-23
PT2291080E (pt) 2015-10-30
DK2291080T3 (en) 2015-12-07
EP3782991A1 (en) 2021-02-24
US20120329838A1 (en) 2012-12-27
US20100010001A1 (en) 2010-01-14
US20150057307A1 (en) 2015-02-26
EA201001785A1 (ru) 2011-10-31
US20120329840A1 (en) 2012-12-27
AU2015213309B2 (en) 2016-10-13
AU2009258242B2 (en) 2015-07-16
US9975863B2 (en) 2018-05-22
US8466183B2 (en) 2013-06-18
LTC2291080I2 (lt) 2021-09-10
EP2913326A1 (en) 2015-09-02
CY1123338T1 (el) 2020-11-25
US10544136B2 (en) 2020-01-28
EP2291080A1 (en) 2011-03-09
EA021672B1 (ru) 2015-08-31
NO2020034I1 (no) 2020-09-29
AU2015213309A1 (en) 2015-09-03
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NZ589617A (en) 2012-06-29
JP2016041736A (ja) 2016-03-31
US20180009770A1 (en) 2018-01-11
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FI2291080T3 (fi) 2015-10-15
FI2291080T5 (fi) 2023-11-06
US20190084947A1 (en) 2019-03-21
EP2913326B1 (en) 2020-07-15
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EP2291080A4 (en) 2013-09-11
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US8481573B2 (en) 2013-07-09
SI2291080T1 (sl) 2015-11-30
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