FI955604L - 3-(indol-3-yyli)propenoiinihappojohdannaiset NMDA-antagonisteina - Google Patents
3-(indol-3-yyli)propenoiinihappojohdannaiset NMDA-antagonisteina Download PDFInfo
- Publication number
- FI955604L FI955604L FI955604A FI955604A FI955604L FI 955604 L FI955604 L FI 955604L FI 955604 A FI955604 A FI 955604A FI 955604 A FI955604 A FI 955604A FI 955604 L FI955604 L FI 955604L
- Authority
- FI
- Finland
- Prior art keywords
- indol
- acid derivatives
- propenoic acid
- nmda antagonists
- nmda
- Prior art date
Links
- PLVPPLCLBIEYEA-UHFFFAOYSA-N 3-(1h-indol-3-yl)prop-2-enoic acid Chemical class C1=CC=C2C(C=CC(=O)O)=CNC2=C1 PLVPPLCLBIEYEA-UHFFFAOYSA-N 0.000 title 1
- HOKKHZGPKSLGJE-GSVOUGTGSA-N N-Methyl-D-aspartic acid Chemical compound CN[C@@H](C(O)=O)CC(O)=O HOKKHZGPKSLGJE-GSVOUGTGSA-N 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Vascular Medicine (AREA)
- Pain & Pain Management (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Urology & Nephrology (AREA)
- Anesthesiology (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US6836793A | 1993-05-27 | 1993-05-27 | |
| US13932393A | 1993-10-19 | 1993-10-19 | |
| US19081494A | 1994-02-02 | 1994-02-02 | |
| PCT/US1994/005023 WO1994027964A1 (en) | 1993-05-27 | 1994-05-02 | 3-(indol-3-yl) propenoic acid derivatives and as nmda antagonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI955604L true FI955604L (fi) | 1995-11-21 |
| FI955604A0 FI955604A0 (fi) | 1995-11-21 |
Family
ID=27371322
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI955604A FI955604A0 (fi) | 1993-05-27 | 1995-11-21 | 3-(indol-3-yyli)propenoiinihappojohdannaiset NMDA-antagonisteina |
Country Status (17)
| Country | Link |
|---|---|
| EP (1) | EP0701551B1 (fi) |
| JP (1) | JP3334805B2 (fi) |
| KR (1) | KR100314482B1 (fi) |
| CN (1) | CN1051302C (fi) |
| AT (1) | ATE151750T1 (fi) |
| AU (1) | AU681402B2 (fi) |
| CA (1) | CA2161768C (fi) |
| DE (1) | DE69402703T2 (fi) |
| DK (1) | DK0701551T3 (fi) |
| ES (1) | ES2103590T3 (fi) |
| FI (1) | FI955604A0 (fi) |
| GR (1) | GR3023973T3 (fi) |
| HU (1) | HU216633B (fi) |
| IL (1) | IL109744A (fi) |
| NO (1) | NO306021B1 (fi) |
| TW (1) | TW262467B (fi) |
| WO (1) | WO1994027964A1 (fi) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9304500D0 (en) * | 1993-03-05 | 1993-04-21 | Glaxo Spa | Heterocyclic compounds |
| US5563157B1 (en) * | 1994-10-31 | 1999-02-02 | Hoecst Marion Roussel Inc | Heterocycle substituted propenoic acid derivatives and pharmaceutical compositions thereof |
| NZ334343A (en) * | 1996-09-30 | 2001-01-26 | Hoechst Marion Roussel Inc | NMDA (n-methyl-d-aspartate) antagonists which preferentially bind to the strychnine-insensitive glycine binding site on the NMDA receptor complex |
| CN101770315B (zh) | 2009-01-05 | 2012-05-23 | 鸿富锦精密工业（深圳）有限公司 | 具有滑动控制的触摸电子装置及其滑动控制方法 |
| CN113419008B (zh) * | 2021-06-29 | 2023-02-07 | 国家烟草质量监督检验中心 | 一种氟噻虫砜代谢物的合相色谱串联质谱测定方法 |
| CN113419009B (zh) * | 2021-06-29 | 2023-02-07 | 国家烟草质量监督检验中心 | 一种氟噻虫砜代谢物的液相色谱串联质谱测定方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5284862A (en) * | 1991-03-18 | 1994-02-08 | Warner-Lambert Company | Derivatives of 2-carboxyindoles having pharmaceutical activity |
| GB9208492D0 (en) * | 1992-04-16 | 1992-06-03 | Glaxo Spa | Heterocyclic compounds |
| JP6788745B2 (ja) * | 2017-07-25 | 2020-11-25 | 株式会社日立ハイテク | 自動分析装置 |
-
1994
- 1994-05-02 HU HU9503367A patent/HU216633B/hu not_active IP Right Cessation
- 1994-05-02 DK DK94916035.2T patent/DK0701551T3/da active
- 1994-05-02 DE DE69402703T patent/DE69402703T2/de not_active Expired - Lifetime
- 1994-05-02 JP JP50066395A patent/JP3334805B2/ja not_active Expired - Lifetime
- 1994-05-02 ES ES94916035T patent/ES2103590T3/es not_active Expired - Lifetime
- 1994-05-02 CN CN94192246A patent/CN1051302C/zh not_active Expired - Fee Related
- 1994-05-02 EP EP94916035A patent/EP0701551B1/en not_active Expired - Lifetime
- 1994-05-02 AT AT94916035T patent/ATE151750T1/de not_active IP Right Cessation
- 1994-05-02 AU AU67843/94A patent/AU681402B2/en not_active Ceased
- 1994-05-02 KR KR1019950705393A patent/KR100314482B1/ko not_active Expired - Fee Related
- 1994-05-02 CA CA002161768A patent/CA2161768C/en not_active Expired - Lifetime
- 1994-05-02 WO PCT/US1994/005023 patent/WO1994027964A1/en active IP Right Grant
- 1994-05-24 TW TW083104700A patent/TW262467B/zh active
- 1994-05-24 IL IL10974494A patent/IL109744A/xx not_active IP Right Cessation
-
1995
- 1995-11-21 FI FI955604A patent/FI955604A0/fi unknown
- 1995-11-24 NO NO954769A patent/NO306021B1/no not_active IP Right Cessation
-
1997
- 1997-07-02 GR GR970401624T patent/GR3023973T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| IL109744A (en) | 1999-06-20 |
| DE69402703T2 (de) | 1997-11-27 |
| DK0701551T3 (da) | 1997-10-20 |
| EP0701551B1 (en) | 1997-04-16 |
| HUT74620A (en) | 1997-01-28 |
| NO954769L (no) | 1996-01-25 |
| ATE151750T1 (de) | 1997-05-15 |
| CN1051302C (zh) | 2000-04-12 |
| AU6784394A (en) | 1994-12-20 |
| HU216633B (hu) | 1999-07-28 |
| JPH09508615A (ja) | 1997-09-02 |
| KR100314482B1 (ko) | 2002-02-28 |
| NO306021B1 (no) | 1999-09-06 |
| WO1994027964A1 (en) | 1994-12-08 |
| ES2103590T3 (es) | 1997-09-16 |
| CA2161768A1 (en) | 1994-12-08 |
| TW262467B (fi) | 1995-11-11 |
| AU681402B2 (en) | 1997-08-28 |
| GR3023973T3 (en) | 1997-10-31 |
| CA2161768C (en) | 1998-08-18 |
| HU9503367D0 (en) | 1996-01-29 |
| DE69402703D1 (de) | 1997-05-22 |
| NO954769D0 (no) | 1995-11-24 |
| KR960702438A (ko) | 1996-04-27 |
| CN1124484A (zh) | 1996-06-12 |
| IL109744A0 (en) | 1994-08-26 |
| EP0701551A1 (en) | 1996-03-20 |
| JP3334805B2 (ja) | 2002-10-15 |
| FI955604A0 (fi) | 1995-11-21 |
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