FI944805A - Indolijohdannaisia 5-HT1-kaltaisina agonisteina - Google Patents
Indolijohdannaisia 5-HT1-kaltaisina agonisteina Download PDFInfo
- Publication number
- FI944805A FI944805A FI944805A FI944805A FI944805A FI 944805 A FI944805 A FI 944805A FI 944805 A FI944805 A FI 944805A FI 944805 A FI944805 A FI 944805A FI 944805 A FI944805 A FI 944805A
- Authority
- FI
- Finland
- Prior art keywords
- agonists
- indole derivatives
- indole
- derivatives
- Prior art date
Links
- 239000000556 agonist Substances 0.000 title 1
- 229940054051 antipsychotic indole derivative Drugs 0.000 title 1
- 150000002475 indoles Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/10—Compounds having one or more C—Si linkages containing nitrogen having a Si-N linkage
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/22—Tin compounds
- C07F7/2208—Compounds having tin linked only to carbon, hydrogen and/or halogen
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pain & Pain Management (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929208161A GB9208161D0 (en) | 1992-04-14 | 1992-04-14 | Indoles |
| PCT/EP1993/000867 WO1993021178A1 (en) | 1992-04-14 | 1993-04-08 | Indole derivatives as 5-ht1-like agonists |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI944805A0 FI944805A0 (fi) | 1994-10-12 |
| FI944805A true FI944805A (fi) | 1994-10-12 |
Family
ID=10713993
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI944805A FI944805A (fi) | 1992-04-14 | 1994-10-12 | Indolijohdannaisia 5-HT1-kaltaisina agonisteina |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US5502065A (fi) |
| EP (1) | EP0636129A1 (fi) |
| JP (1) | JP2540017B2 (fi) |
| CN (1) | CN1082040A (fi) |
| AU (1) | AU3952693A (fi) |
| CA (1) | CA2117498A1 (fi) |
| FI (1) | FI944805A (fi) |
| GB (1) | GB9208161D0 (fi) |
| IL (1) | IL105312A0 (fi) |
| TW (1) | TW224095B (fi) |
| WO (1) | WO1993021178A1 (fi) |
| ZA (1) | ZA932582B (fi) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5559129A (en) * | 1990-10-15 | 1996-09-24 | Pfizer Inc | Indole derivatives |
| US5559246A (en) * | 1990-10-15 | 1996-09-24 | Pfizer Inc. | Indole derivatives |
| US5607951A (en) * | 1990-10-15 | 1997-03-04 | Pfizer Inc | Indole derivatives |
| US5545644A (en) * | 1990-10-15 | 1996-08-13 | Pfizer Inc. | Indole derivatives |
| US5578612A (en) * | 1990-10-15 | 1996-11-26 | Pfizer Inc. | Indole derivatives |
| JPH07509452A (ja) * | 1992-07-24 | 1995-10-19 | メルク シヤープ エンド ドーム リミテツド | イミダゾール，トリアゾール及びテトラゾール誘導体 |
| WO1995006636A1 (en) * | 1993-08-31 | 1995-03-09 | Pfizer Inc. | 5-arylindole derivatives |
| ES2079323B1 (es) * | 1994-06-21 | 1996-10-16 | Vita Invest Sa | Derivados de indol utiles para el tratamiento de la migraña, composicion y uso correspondientes. |
| GB9417310D0 (en) | 1994-08-27 | 1994-10-19 | Pfizer Ltd | Therapeutic agents |
| GB9420503D0 (en) * | 1994-10-11 | 1994-11-23 | Pfizer Ltd | Therapeutic agents |
| GB9420529D0 (en) | 1994-10-12 | 1994-11-30 | Pfizer Ltd | Indoles |
| FR2737721B1 (fr) * | 1995-08-08 | 1997-09-05 | Roussel Uclaf | Nouveaux composes biphenyles, leur procede de preparation et les intermediaires de ce procede, leur application a titre de medicament et les compositions pharmaceutiques les contenant |
| WO1997043281A1 (en) * | 1996-05-16 | 1997-11-20 | Allelix Biopharmaceuticals Inc. | Thiophene- and furan-tryptamine derivatives |
| US5770742A (en) * | 1996-05-16 | 1998-06-23 | Allelix Biopharmaceuticals Inc. | Thiophene-tryptamine derivatives |
| US5998438A (en) * | 1996-11-26 | 1999-12-07 | Allelix Biopharmaceuticals, Inc. | 5-cyclo indole compounds |
| US5994352A (en) * | 1998-11-13 | 1999-11-30 | Pfizer Inc. | 5-arylindole derivatives |
| FR2799463B1 (fr) * | 1999-10-12 | 2004-04-16 | Adir | Nouveaux composes cyano-indoles inhibiteurs de recapture de serotonine, leur procede de preparation et ces compositions pharmaceutiques qui les contiennent |
| US8785403B2 (en) | 2003-08-01 | 2014-07-22 | Mitsubishi Tanabe Pharma Corporation | Glucopyranoside compound |
| CA2534024C (en) | 2003-08-01 | 2009-06-02 | Tanabe Seiyaku Co., Ltd. | Novel compounds having inhibitory activity against sodium-dependant transporter |
| UY30730A1 (es) | 2006-12-04 | 2008-07-03 | Mitsubishi Tanabe Pharma Corp | Forma cristalina del hemihidrato de 1-(b (beta)-d-glucopiranosil) -4-metil-3-[5-(4-fluorofenil) -2-tienilmetil]benceno |
| RS56990B1 (sr) | 2007-09-10 | 2018-05-31 | Janssen Pharmaceutica Nv | Postupak za dobijanje jedinjenja koja su korisna kao inhibitori sglt |
| CL2008003653A1 (es) | 2008-01-17 | 2010-03-05 | Mitsubishi Tanabe Pharma Corp | Uso de un inhibidor de sglt derivado de glucopiranosilo y un inhibidor de dppiv seleccionado para tratar la diabetes; y composicion farmaceutica. |
| US9056850B2 (en) | 2008-10-17 | 2015-06-16 | Janssen Pharmaceutica N.V. | Process for the preparation of compounds useful as inhibitors of SGLT |
| US20110009347A1 (en) | 2009-07-08 | 2011-01-13 | Yin Liang | Combination therapy for the treatment of diabetes |
| RS55909B1 (sr) | 2009-10-14 | 2017-09-29 | Janssen Pharmaceutica Nv | Proces za pripremu jedinjenja koja su korisna kao inhibitori sglt2 |
| EA022365B1 (ru) | 2010-05-11 | 2015-12-30 | Янссен Фармацевтика Нв | Фармацевтические композиции, содержащие производные 1-(бета-d-глюкопиранозил)-2-тиенилметилбензола как ингибиторы нзпг |
| WO2012004811A1 (en) * | 2010-07-06 | 2012-01-12 | Ind-Swift Laboratories Limited | Process for the preparation of 5-substsituted indole derivative |
| ES2586846T3 (es) | 2011-04-13 | 2016-10-19 | Janssen Pharmaceutica, N.V. | Proceso de preparación de compuestos útiles como inhibidores de SGLT2 |
| US9035044B2 (en) | 2011-05-09 | 2015-05-19 | Janssen Pharmaceutica Nv | L-proline and citric acid co-crystals of (2S, 3R, 4R, 5S,6R)-2-(3-((5-(4-fluorophenyl)thiopen-2-yl)methyl)4-methylphenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol |
| WO2014055595A1 (en) | 2012-10-05 | 2014-04-10 | Merck Sharp & Dohme Corp. | Indoline compounds as aldosterone synthase inhibitiors related applications |
| US10730866B2 (en) * | 2014-04-07 | 2020-08-04 | Purdue Pharma L.P. | Indole derivatives and use thereof |
| US20170071970A1 (en) | 2015-09-15 | 2017-03-16 | Janssen Pharmaceutica Nv | Co-therapy comprising canagliflozin and phentermine for the treatment of obesity and obesity related disorders |
| JP2019502761A (ja) * | 2016-01-21 | 2019-01-31 | ラボラトリオス レヴィ エセエレ | （（ｒ）−３−［（−１−メチルピロリジン−２−イル）メチル］−５−（２−フェニルスルホニルエチル）−１ｈ−インドールを作製する方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL96891A0 (en) * | 1990-01-17 | 1992-03-29 | Merck Sharp & Dohme | Indole-substituted five-membered heteroaromatic compounds,their preparation and pharmaceutical compositions containing them |
| WO1991018897A1 (en) * | 1990-06-07 | 1991-12-12 | The Wellcome Foundation Limited | Therapeutic heterocyclic compounds |
| DK0592438T5 (da) * | 1990-10-15 | 1999-12-06 | Pfizer Inc. | Indolderivater |
-
1992
- 1992-04-14 GB GB929208161A patent/GB9208161D0/en active Pending
-
1993
- 1993-04-05 IL IL105312A patent/IL105312A0/xx unknown
- 1993-04-08 WO PCT/EP1993/000867 patent/WO1993021178A1/en not_active Application Discontinuation
- 1993-04-08 JP JP5517960A patent/JP2540017B2/ja not_active Expired - Lifetime
- 1993-04-08 US US08/307,566 patent/US5502065A/en not_active Expired - Fee Related
- 1993-04-08 CA CA002117498A patent/CA2117498A1/en not_active Abandoned
- 1993-04-08 AU AU39526/93A patent/AU3952693A/en not_active Abandoned
- 1993-04-08 EP EP93908928A patent/EP0636129A1/en not_active Withdrawn
- 1993-04-12 TW TW082102725A patent/TW224095B/zh active
- 1993-04-13 ZA ZA932582A patent/ZA932582B/xx unknown
- 1993-04-14 CN CN93105704A patent/CN1082040A/zh active Pending
-
1994
- 1994-10-12 FI FI944805A patent/FI944805A/fi unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JP2540017B2 (ja) | 1996-10-02 |
| TW224095B (fi) | 1994-05-21 |
| ZA932582B (en) | 1994-10-13 |
| WO1993021178A1 (en) | 1993-10-28 |
| FI944805A0 (fi) | 1994-10-12 |
| GB9208161D0 (en) | 1992-05-27 |
| EP0636129A1 (en) | 1995-02-01 |
| US5502065A (en) | 1996-03-26 |
| AU3952693A (en) | 1993-11-18 |
| CA2117498A1 (en) | 1993-10-28 |
| JPH07502537A (ja) | 1995-03-16 |
| CN1082040A (zh) | 1994-02-16 |
| IL105312A0 (en) | 1993-08-18 |
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