FI943421L - 1,5-bentsodiatsepiinijohdannaiset ja niiden käyttö lääkkeenä - Google Patents

1,5-bentsodiatsepiinijohdannaiset ja niiden käyttö lääkkeenä Download PDF

Info

Publication number: FI943421L
Authority: FI; Finland
Prior art keywords: medicine; benzodiazepine derivatives; benzodiazepine; derivatives
Prior art date: 1992-01-21

Application number

FI943421A

Other languages

English (en)

Swedish (sv)

Other versions

FI111632B (fi

FI943421A0 (fi

Inventor

Harry Finch

David Gordon Trist

Giorgio Tarzia

Aldo Feriani

Original Assignee

Glaxo Spa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1992-01-21

Filing date

1994-07-19

Publication date

1994-07-19

1994-07-19 Application filed by Glaxo Spa filed Critical Glaxo Spa

1994-07-19 Publication of FI943421A0 publication Critical patent/FI943421A0/fi

1994-07-19 Publication of FI943421L publication Critical patent/FI943421L/fi

2003-08-29 Application granted granted Critical

2003-08-29 Publication of FI111632B publication Critical patent/FI111632B/fi

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/12—1,5-Benzodiazepines; Hydrogenated 1,5-benzodiazepines
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Chemical & Material Sciences (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Life Sciences & Earth Sciences (AREA)
Veterinary Medicine (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Pharmacology & Pharmacy (AREA)
Chemical Kinetics & Catalysis (AREA)
Animal Behavior & Ethology (AREA)
General Health & Medical Sciences (AREA)
Public Health (AREA)
Medicinal Chemistry (AREA)
Biomedical Technology (AREA)
Neurology (AREA)
Neurosurgery (AREA)
Psychiatry (AREA)
Pain & Pain Management (AREA)
Psychology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Plural Heterocyclic Compounds (AREA)

FI943421A 1992-01-21 1994-07-19 Menetelmä CCK-B-antagonistisesti vaikuttavien 1,5-bentsodiatsepiinijohdannaisten valmistamiseksi FI111632B (fi)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
GB929201180A GB9201180D0 (en)	1992-01-21	1992-01-21	Chemical compounds
GB9201180		1992-01-21
EP9300098		1993-01-19
PCT/EP1993/000098 WO1993014074A1 (en)	1992-01-21	1993-01-19	1,5-benzodiazepine derivatives and their use in medicine

Publications (3)

Publication Number	Publication Date
FI943421A0 FI943421A0 (fi)	1994-07-19
FI943421L true FI943421L (fi)	1994-07-19
FI111632B FI111632B (fi)	2003-08-29

Family

ID=10708914

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
FI943421A FI111632B (fi)	1992-01-21	1994-07-19	Menetelmä CCK-B-antagonistisesti vaikuttavien 1,5-bentsodiatsepiinijohdannaisten valmistamiseksi

Country Status (29)

Country	Link
US (2)	US5580895A (fi)
JP (1)	JP3253723B2 (fi)
KR (1)	KR100263625B1 (fi)
CN (1)	CN1049217C (fi)
AP (1)	AP369A (fi)
AU (2)	AU3450193A (fi)
BG (1)	BG61876B1 (fi)
CA (1)	CA2087672C (fi)
CZ (1)	CZ283950B6 (fi)
FI (1)	FI111632B (fi)
GB (1)	GB9201180D0 (fi)
GE (1)	GEP20001968B (fi)
HU (2)	HU221297B1 (fi)
IL (1)	IL104447A (fi)
IS (1)	IS3970A (fi)
MX (1)	MX9300261A (fi)
MY (1)	MY131307A (fi)
NO (1)	NO305952B1 (fi)
NZ (1)	NZ245715A (fi)
OA (1)	OA09964A (fi)
PH (1)	PH30894A (fi)
PL (1)	PL175340B1 (fi)
RO (1)	RO114128B1 (fi)
RU (1)	RU2124009C1 (fi)
SK (1)	SK280173B6 (fi)
TW (1)	TW226013B (fi)
UA (1)	UA29416C2 (fi)
WO (1)	WO1993014074A1 (fi)
ZA (1)	ZA93375B (fi)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB9225492D0 (en) *	1992-12-05	1993-01-27	Glaxo Group Ltd	Amine derivatives
GB9307833D0 (en) *	1993-04-15	1993-06-02	Glaxo Inc	Modulators of cholecystokinin and gastrin
HUT74091A (en) *	1993-04-15	1996-11-28	Glaxo Wellcome Inc	1,5-benzodiazepine derivatives having cck and/or gastrin antagonistic activity
GB9308431D0 (en) *	1993-04-23	1993-06-09	Glaxo Spa	Chemical compounds
GB9308421D0 (en) *	1993-04-23	1993-06-09	Glaxo Spa	Chemical compounds
GB2280182A (en) *	1993-07-20	1995-01-25	Glaxo Spa	Benzodiazepine derivatives
GB9314981D0 (en) *	1993-07-20	1993-09-01	Glaxo Spa	Chemical compounds
GB9315018D0 (en) *	1993-07-20	1993-09-01	Glaxo Spa	Chemical compounds
GB9314977D0 (en) *	1993-07-20	1993-09-01	Glaxo Spa	Chemical compounds
US5739129A (en) *	1994-04-14	1998-04-14	Glaxo Wellcome Inc.	CCK or gastrin modulating 5-heterocyclic-1, 5 benzodiazepines
HUT76135A (en) *	1994-04-14	1997-06-30	Glaxo Wellcome Inc	Cholecystokinin and gastrin modulating 5-heterocyclic-1,5-benzodiazepines
PE27497A1 (es) *	1994-04-15	1997-08-07	Glaxo Inc	Derivados de 1,5 benzodiazepina
GB9420748D0 (en) *	1994-10-14	1994-11-30	Glaxo Inc	1,5 benzodiazepine derivatives
US5780464A (en) *	1994-10-14	1998-07-14	Glaxo Wellcome Inc.	Enteric coated compositions of 1,5-benzodiazepine derivatives having CCK antagonistic or agonistic activity
US5750353A (en) *	1995-12-11	1998-05-12	New England Medical Center Hospitals, Inc.	Assay for non-peptide agonists to peptide hormone receptors
DE69637211T2 (de)	1995-12-11	2008-05-08	New England Medical Center Hospitals, Inc., Boston	Test für und verwendungen von liganden von peptidhormonrezeptoren.
DE69724644D1 (de) *	1996-12-10	2003-10-09	Zeria Pharm Co Ltd	1,5-benzodiazepinderivate
WO2004064730A2 (en)	2003-01-14	2004-08-05	Cytokinetics, Inc.	Compounds, compositions and methods
GB0307918D0 (en) *	2003-04-05	2003-05-14	Astrazeneca Ab	Therapeutic use
RU2377987C2 (ru) *	2003-11-18	2010-01-10	Бёрингер Ингельхайм Интернациональ Гмбх	Твердая лекарственная форма
RS53600B1 (en)	2004-06-17	2015-02-27	Cytokinetics, Inc.	UNITS, PREPARATIONS AND METHODS
US7538223B2 (en)	2005-08-04	2009-05-26	Cytokinetics, Inc.	Compounds, compositions and methods
US7825120B2 (en)	2005-12-15	2010-11-02	Cytokinetics, Inc.	Certain substituted ((piperazin-1-ylmethyl)benzyl)ureas
EP1959960B1 (en)	2005-12-15	2013-04-10	Cytokinetics, Inc.	Certain chemical entities, compositions and methods
WO2007078815A2 (en)	2005-12-16	2007-07-12	Cytokinetics, Inc.	Certain chemical entities, compositions, and methods
EP1962852B1 (en)	2005-12-19	2017-01-25	Cytokinetics, Inc.	Compounds, compositions and methods
CU20090172A6 (es)	2009-10-09	2011-10-05	Facultad De Quimica Universidad De La Habana	Sistemas tricíclicos y tetracíclicos con actividad sobre el sistema nervioso central y vascular
US9725490B2 (en)	2011-07-29	2017-08-08	Tokushima University	ERAP1-derived peptide and use thereof
CN103435562B (zh) *	2013-08-26	2016-02-24	华东理工大学	6-取代苯并二氮卓-2,4-二酮类化合物及其用途
NZ739226A (en)	2015-07-22	2022-11-25	Enanta Pharm Inc	Benzodiazepine derivatives as rsv inhibitors
EP3402799B1 (en)	2016-01-15	2022-05-04	Enanta Pharmaceuticals, Inc.	Heterocyclic compounds as rsv inhibitors
KR102573499B1 (ko)	2017-02-16	2023-08-31	이난타 파마슈티칼스, 인코포레이티드	벤조디아제핀 유도체의 제조 방법
US10752598B2 (en) *	2017-06-07	2020-08-25	Enanta Pharmaceuticals, Inc.	Aryldiazepine derivatives as RSV inhibitors
US11091501B2 (en)	2017-06-30	2021-08-17	Enanta Pharmaceuticals, Inc.	Heterocyclic compounds as RSV inhibitors
WO2019006291A1 (en)	2017-06-30	2019-01-03	Enanta Pharmaceuticals, Inc.	HETEROCYCLIC COMPOUNDS AS RSV INHIBITORS
CN111386118B (zh)	2017-09-29	2023-05-09	英安塔制药有限公司	作为rsv抑制剂的组合药物剂
WO2019094920A1 (en)	2017-11-13	2019-05-16	Enanta Pharmaceuticals, Inc.	Azepin-2-one derivatives as rsv inhibitors
WO2019199908A1 (en)	2018-04-11	2019-10-17	Enanta Pharmaceuticals, Inc.	Heterocyclic compounds as rsv inhibitors
US20220098256A1 (en)	2018-11-30	2022-03-31	Tokushima University	Therapeutic agent for breast cancer comprising big3-phb2 interaction-inhibiting peptide derived from phb2
JP7558189B2 (ja)	2019-03-18	2024-09-30	エナンタファーマシューティカルズインコーポレイテッド	Ｒｓｖ阻害剤としてのベンゾジアゼピン誘導体
WO2020210246A1 (en)	2019-04-09	2020-10-15	Enanta Pharmaceuticals, Inc,	Heterocyclic compounds as rsv inhibitors
US11505558B1 (en)	2019-10-04	2022-11-22	Enanta Pharmaceuticals, Inc.	Antiviral heterocyclic compounds
UY39032A (es)	2020-01-24	2021-07-30	Enanta Pharm Inc	Compuestos heterocíclicos como agentes antivirales
US11534439B2 (en)	2020-07-07	2022-12-27	Enanta Pharmaceuticals, Inc.	Dihydroquinoxaline and dihydropyridopyrazine derivatives as RSV inhibitors
WO2022086840A1 (en)	2020-10-19	2022-04-28	Enanta Pharmaceuticals, Inc.	Heterocyclic compounds as anti-viral agents
US12162857B2 (en)	2022-04-27	2024-12-10	Enanta Pharmaceuticals, Inc.	Antiviral compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
FR2641280B1 (fr) *	1988-12-29	1994-01-21	Roussel Uclaf	Nouveaux derives de la 2,4-dioxo 2,3,4,5-tetrahydro 1h-1,5-benzodiazepine, leur procede de preparation et leur application comme medicaments

1992
- 1992-01-21 GB GB929201180A patent/GB9201180D0/en active Pending
- 1992-01-21 GE GEAP19922651A patent/GEP20001968B/en unknown
1993
- 1993-01-15 US US08/256,359 patent/US5580895A/en not_active Expired - Fee Related
- 1993-01-19 UA UA94005364A patent/UA29416C2/uk unknown
- 1993-01-19 RU RU94037768A patent/RU2124009C1/ru active
- 1993-01-19 RO RO94-01216A patent/RO114128B1/ro unknown
- 1993-01-19 KR KR1019940702491A patent/KR100263625B1/ko not_active IP Right Cessation
- 1993-01-19 WO PCT/EP1993/000098 patent/WO1993014074A1/en active IP Right Grant
- 1993-01-19 CZ CZ941736A patent/CZ283950B6/cs not_active IP Right Cessation
- 1993-01-19 SK SK864-94A patent/SK280173B6/sk unknown
- 1993-01-19 PL PL93304684A patent/PL175340B1/pl unknown
- 1993-01-19 AU AU34501/93A patent/AU3450193A/en not_active Abandoned
- 1993-01-19 HU HU9402150A patent/HU221297B1/hu not_active IP Right Cessation
- 1993-01-20 ZA ZA93375A patent/ZA93375B/xx unknown
- 1993-01-20 AU AU31935/93A patent/AU661749B2/en not_active Ceased
- 1993-01-20 CA CA002087672A patent/CA2087672C/en not_active Expired - Fee Related
- 1993-01-20 MX MX9300261A patent/MX9300261A/es not_active IP Right Cessation
- 1993-01-20 AP APAP/P/1993/000478A patent/AP369A/en active
- 1993-01-20 NZ NZ245715A patent/NZ245715A/en unknown
- 1993-01-20 PH PH45583A patent/PH30894A/en unknown
- 1993-01-20 IS IS3970A patent/IS3970A/is unknown
- 1993-01-20 MY MYPI93000093A patent/MY131307A/en unknown
- 1993-01-20 IL IL104447A patent/IL104447A/en not_active IP Right Cessation
- 1993-01-20 JP JP02483193A patent/JP3253723B2/ja not_active Expired - Fee Related
- 1993-01-21 CN CN93101143A patent/CN1049217C/zh not_active Expired - Fee Related
- 1993-02-02 TW TW082100666A patent/TW226013B/zh active
1994
- 1994-06-27 BG BG98881A patent/BG61876B1/bg unknown
- 1994-07-18 OA OA60539A patent/OA09964A/en unknown
- 1994-07-19 FI FI943421A patent/FI111632B/fi active
- 1994-07-20 NO NO942720A patent/NO305952B1/no unknown
1995
- 1995-06-16 HU HU95P/P00242P patent/HU211295A9/hu unknown
1996
- 1996-07-01 US US08/674,259 patent/US5637697A/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
UA29416C2 (uk)	2000-11-15
RO114128B1 (ro)	1999-01-29
KR100263625B1 (ko)	2000-11-01
JP3253723B2 (ja)	2002-02-04
AP9300478A0 (en)	1993-01-31
NO305952B1 (no)	1999-08-23
GEP20001968B (en)	2000-03-05
BG61876B1 (bg)	1998-08-31
HUT67375A (en)	1995-03-28
MX9300261A (es)	1994-03-31
FI111632B (fi)	2003-08-29
GB9201180D0 (en)	1992-03-11
HU211295A9 (en)	1995-11-28
HU9402150D0 (en)	1994-09-28
SK86494A3 (en)	1995-03-08
CN1074678A (zh)	1993-07-28
CZ283950B6 (cs)	1998-07-15
CA2087672C (en)	2003-08-05
US5580895A (en)	1996-12-03
IL104447A0 (en)	1993-05-13
PH30894A (en)	1997-12-23
CZ173694A3 (en)	1995-09-13
IS3970A (is)	1993-07-22
AP369A (en)	1994-11-06
TW226013B (fi)	1994-07-01
NZ245715A (en)	1995-07-26
RU2124009C1 (ru)	1998-12-27
SK280173B6 (sk)	1999-09-10
RU94037768A (ru)	1996-08-10
HU221297B1 (en)	2002-09-28
BG98881A (bg)	1995-03-31
JPH07118244A (ja)	1995-05-09
ZA93375B (en)	1994-07-18
AU661749B2 (en)	1995-08-03
NO942720L (no)	1994-07-20
AU3193593A (en)	1993-07-22
NO942720D0 (no)	1994-07-20
US5637697A (en)	1997-06-10
FI943421A0 (fi)	1994-07-19
IL104447A (en)	1998-02-22
OA09964A (en)	1995-12-11
MY131307A (en)	2007-08-30
CA2087672A1 (en)	1993-07-22
CN1049217C (zh)	2000-02-09
AU3450193A (en)	1993-08-03
PL175340B1 (pl)	1998-12-31
WO1993014074A1 (en)	1993-07-22

Publication	Publication Date	Title
FI943421L (fi)	1994-07-19	1,5-bentsodiatsepiinijohdannaiset ja niiden käyttö lääkkeenä
FI953479A0 (fi)	1995-07-18	1-aryylipyrimidiinijohdannaiset ja niiden farmaseuttinen käyttö
FI961599A (fi)	1996-06-07	1N-alkyyli-N-aryylipyrimidiiniamiineja ja niiden johdannaisia
FI945281L (fi)	1995-05-11	Heterosykliset yhdisteet, niiden valmistus ja käyttö
FI962589L (fi)	1996-08-20	2,4-disulfofenyylibutyylinitroni, sen suolat ja niiden käyttö farmaseuttisina aineina
FI945625L (fi)	1994-11-29	Indolokarbatsoli-imidit ja niiden käyttö
FI953666L (fi)	1995-09-28	Hetersykliset yhdisteet ja niiden valmistus ja käyttö
HUP0000474A3 (en)	2001-06-28	Arylethenesulfonamide derivatives and drug composition containing the same
FI954131L (fi)	1995-09-04	Heterosykliset yhdisteet ja niiden valmistus ja käyttö
FI940904L (fi)	1994-11-29	Oksatsolidiinidionijohdannaiset, niiden valmistus ja käyttö
FI955235L (fi)	1996-05-03	Oksatsolidiinionijohdannaiset, niiden valmistus ja käyttö
FI954130L (fi)	1995-10-27	Heterosykliset yhdisteet ja niiden valmistus ja käyttö
FI935887L (fi)	1994-06-29	Tiatzolidiinidionijohdannaiset, niiden valmistus ja käyttö
FI943313L (fi)	1994-07-12	Heterosykliset yhdisteet ja niiden valmistus ja käyttö
FI953021A0 (fi)	1995-06-19	4-bentsoyyli-isoksatsolin johdannaisia ja niiden käyttö herbisideinä
FI964482L (fi)	1996-11-07	Amidijohdannaisia ja niiden käyttö lääkkeenä
FI954229L (fi)	1995-09-08	Heterosykliset yhdisteet, niiden käyttö ja valmistus
FI955679A0 (fi)	1995-11-24	Piperidiinijohdannaisia, niiden valmistus ja käyttö
FI961977L (fi)	1996-05-09	N-substituoidut atsabisykloalkaanijohdannaiset, niiden valmistus ja käyttö
FI944728L (fi)	1994-10-07	Uudet perhydroisoindolijohdannaiset ja niiden valmistus
ZA896039B (en)	1991-04-24	Benzodiazepine compounds and their use as pharmaceuticals
FI941963L (fi)	1994-10-29	Pyridiinijohdannaiset, niiden valmistus ja käyttö
FI941214L (fi)	1994-09-16	Bentsimidatsolin johdannaisia, niiden valmistus ja käyttö
FI931794L (fi)	1993-10-23	Monokvaternaera 2,16-bispiperidinylandrostanderivat
ZA913171B (en)	1992-02-26	1,5-benzothiazepinone derivatives,their preparations and pharmaceutical use