[go: up one dir, main page]

FI943313L - Heterosykliset yhdisteet ja niiden valmistus ja käyttö - Google Patents

Heterosykliset yhdisteet ja niiden valmistus ja käyttö Download PDF

Info

Publication number
FI943313L
FI943313L FI943313A FI943313A FI943313L FI 943313 L FI943313 L FI 943313L FI 943313 A FI943313 A FI 943313A FI 943313 A FI943313 A FI 943313A FI 943313 L FI943313 L FI 943313L
Authority
FI
Finland
Prior art keywords
preparation
heterocyclic compounds
heterocyclic
compounds
Prior art date
Application number
FI943313A
Other languages
English (en)
Swedish (sv)
Other versions
FI943313A0 (fi
Inventor
Preben H Olesen
Per Sauerberg
Original Assignee
Novo Nordisk As
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Novo Nordisk As filed Critical Novo Nordisk As
Publication of FI943313A0 publication Critical patent/FI943313A0/fi
Publication of FI943313L publication Critical patent/FI943313L/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D453/00—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids
    • C07D453/02—Heterocyclic compounds containing quinuclidine or iso-quinuclidine ring systems, e.g. quinine alkaloids containing not further condensed quinuclidine ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/08—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI943313A 1992-01-13 1994-07-12 Heterosykliset yhdisteet ja niiden valmistus ja käyttö FI943313L (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
PCT/DK1992/000009 WO1993014089A1 (en) 1992-01-13 1992-01-13 Heterocyclic compounds and their preparation and use
PCT/DK1993/000007 WO1993014090A1 (en) 1992-01-13 1993-01-07 Heterocyclic compounds and their preparation and use

Publications (2)

Publication Number Publication Date
FI943313A0 FI943313A0 (fi) 1994-07-12
FI943313L true FI943313L (fi) 1994-07-12

Family

ID=8153779

Family Applications (1)

Application Number Title Priority Date Filing Date
FI943313A FI943313L (fi) 1992-01-13 1994-07-12 Heterosykliset yhdisteet ja niiden valmistus ja käyttö

Country Status (12)

Country Link
US (2) US5414009A (fi)
EP (1) EP0628041B1 (fi)
JP (1) JP3517234B2 (fi)
AT (1) ATE194617T1 (fi)
AU (1) AU672190B2 (fi)
CA (1) CA2127251A1 (fi)
DE (1) DE69329018T2 (fi)
FI (1) FI943313L (fi)
IL (1) IL104261A (fi)
NO (1) NO302523B1 (fi)
WO (2) WO1993014089A1 (fi)
ZA (1) ZA93218B (fi)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5998404A (en) 1994-10-24 1999-12-07 Eli Lilly And Company Heterocyclic compounds and their use
US5852037A (en) * 1995-11-13 1998-12-22 Eli Lilly And Company Method for treating anxiety
US5889019A (en) * 1995-11-29 1999-03-30 Eli Lilly And Company Heterocyclic compounds and their use
AU1141497A (en) * 1995-11-29 1997-06-19 Eli Lilly And Company Heterocyclic compounds and their use
CA2239301A1 (en) * 1995-12-06 1997-06-12 Charles Howard Mitch Composition for treating pain
WO1997020556A1 (en) * 1995-12-07 1997-06-12 Eli Lilly And Company Method for treating pain
AU2679497A (en) * 1996-04-23 1997-11-12 Eli Lilly And Company Heterocyclic compounds
US6187798B1 (en) * 1996-04-23 2001-02-13 Eli Lilly And Company Heterocyclic compounds
DE69714247T2 (de) * 1996-04-23 2003-01-23 Eli Lilly And Co., Indianapolis Heterozyklische verbindungen
US5834458A (en) * 1996-10-09 1998-11-10 Eli Lilly And Company Heterocyclic compounds and their use
US5733912A (en) * 1997-02-19 1998-03-31 Abbott Laboratories 7A-heterocycle substituted hexahydro-1H-pyrrolizine compounds useful in controlling chemical synaptic transmission
US6528529B1 (en) 1998-03-31 2003-03-04 Acadia Pharmaceuticals Inc. Compounds with activity on muscarinic receptors
WO1999059995A1 (en) * 1998-05-15 1999-11-25 Novo Nordisk A/S Heterocyclic compounds and their preparation and use
US6376675B2 (en) 1999-01-22 2002-04-23 The University Of Toledo Muscarinic receptor agonists
US6096767A (en) * 1999-01-22 2000-08-01 The University Of Toledo Muscarinic receptor agonists
US6211204B1 (en) 1999-01-22 2001-04-03 University Of Toledo Muscarinic receptor agonists
EP2258357A3 (en) 2005-08-26 2011-04-06 Braincells, Inc. Neurogenesis with acetylcholinesterase inhibitor
EP1928437A2 (en) 2005-08-26 2008-06-11 Braincells, Inc. Neurogenesis by muscarinic receptor modulation
WO2007075297A2 (en) * 2005-12-27 2007-07-05 University Of Toledo Muscarinic agonists and methods of use thereof
JP2011520905A (ja) 2008-05-15 2011-07-21 ザ・ユニバーシティ・オブ・トレド 向知性剤としてのムスカリンアゴニスト
WO2009152392A2 (en) * 2008-06-11 2009-12-17 University Of Toledo Muscarinic agonists for neurological disorders and methods of making the same
WO2012149524A1 (en) 2011-04-29 2012-11-01 The University Of Toledo Muscarinic agonists as enhancers of working memory and cognitive flexibility

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ219646A (en) * 1986-03-27 1990-10-26 Merck Sharp & Dohme Oxadiazole derivatives of azacyclics for treating cns disorders
GB8610432D0 (en) * 1986-04-29 1986-06-04 Akzo Nv Amino-thiazole & oxazole derivatives
GB8714789D0 (en) * 1987-06-24 1987-07-29 Lundbeck & Co As H Heterocyclic compounds
GB8717446D0 (en) * 1987-07-23 1987-08-26 Merck Sharp & Dohme Chemical compounds
NZ225999A (en) * 1987-09-10 1992-04-28 Merck Sharp & Dohme Azacyclic- or azabicyclic-substituted thiadiazole derivatives and pharmaceutical compositions
IL88156A (en) * 1987-11-13 1997-02-18 Novo Nordisk As Azacyclic compounds their preparation and pharmaceutical compositions containing them
EP0322182A3 (en) * 1987-12-22 1992-01-02 Beecham Group Plc Azabicyclic compounds, process for their preparation and pharmaceutical compositions containing them
NZ227841A (en) * 1988-02-12 1991-08-27 Merck Sharp & Dohme Heterocyclic compounds with at least two non-condensed five membered rings and pharmaceutical compositions
DK162892C (da) * 1988-07-04 1992-05-11 Novo Nordisk As 1,2,5,6-tetrahydropyridinforbindelser, deres fremstilling og farmaceutiske praeparater indeholdende disse
US5043345A (en) * 1989-02-22 1991-08-27 Novo Nordisk A/S Piperidine compounds and their preparation and use
EP0459568A3 (en) * 1990-05-31 1992-09-30 Merck Sharp & Dohme Ltd. Substituted oxadiazoles and thiadiazoles for use in the treatment of glaucoma and novel compounds having such use
DK198590D0 (da) * 1990-08-21 1990-08-21 Novo Nordisk As Heterocykliske forbindelser, deres fremstilling og anvendelse

Also Published As

Publication number Publication date
FI943313A0 (fi) 1994-07-12
DE69329018T2 (de) 2001-03-22
CA2127251A1 (en) 1993-07-22
WO1993014089A1 (en) 1993-07-22
JPH07502737A (ja) 1995-03-23
NO942610D0 (no) 1994-07-12
AU672190B2 (en) 1996-09-26
ATE194617T1 (de) 2000-07-15
IL104261A (en) 1997-11-20
US5977129A (en) 1999-11-02
JP3517234B2 (ja) 2004-04-12
IL104261A0 (en) 1993-05-13
US5414009A (en) 1995-05-09
AU3448593A (en) 1993-08-03
DE69329018D1 (de) 2000-08-17
ZA93218B (en) 1993-08-17
NO942610L (no) 1994-09-12
EP0628041B1 (en) 2000-07-12
WO1993014090A1 (en) 1993-07-22
NO302523B1 (no) 1998-03-16
EP0628041A1 (en) 1994-12-14

Similar Documents

Publication Publication Date Title
FI953666L (fi) Hetersykliset yhdisteet ja niiden valmistus ja käyttö
FI954131L (fi) Heterosykliset yhdisteet ja niiden valmistus ja käyttö
FI954130L (fi) Heterosykliset yhdisteet ja niiden valmistus ja käyttö
FI955051A0 (fi) Heterosyklisiä yhdisteitä ja niiden valmistus ja käyttö
FI945281L (fi) Heterosykliset yhdisteet, niiden valmistus ja käyttö
FI945625L (fi) Indolokarbatsoli-imidit ja niiden käyttö
FI943313L (fi) Heterosykliset yhdisteet ja niiden valmistus ja käyttö
FI961599A (fi) 1N-alkyyli-N-aryylipyrimidiiniamiineja ja niiden johdannaisia
FI944310L (fi) Heteroaryyliamino- ja heteroaryylisuolfonamidosubstituoituja 3-bentsyyliaminometyylipiperidiinejä ja vastaavia yhdisteitä
FI941137L (fi) 2-debentsoyyli-2-asyylitaksolijohdannaisia ja menetelmiä niiden valmistamiseksi
FI953479A0 (fi) 1-aryylipyrimidiinijohdannaiset ja niiden farmaseuttinen käyttö
FI933001L (fi) Antigastrit-aemne
FI945434L (fi) 4-markatpoasetyyliamino/2/bentsatsepinoni (3) johdannaisia ja niiden käyttö enkefalinaasi-inhibiittoreina
BR1100824A (pt) Composto e composição farmacêutica
FI943421L (fi) 1,5-bentsodiatsepiinijohdannaiset ja niiden käyttö lääkkeenä
FI951197L (fi) Mikrobisidiset koostumukset ja menetelmät
FI944178L (fi) Halikondriinit ja niihin läheisesti liittyvät yhdisteet
FI935887L (fi) Tiatzolidiinidionijohdannaiset, niiden valmistus ja käyttö
FI935728L (fi) Substituoituja 4-fenyylipyridoneja ja 4-fenyyli-2-alkoksipyridiinejä
FI972245A0 (fi) Meso-monojodisubstituoidut tetramakrosykliset yhdisteet sekä niiden valmistus- ja käyttömenetelmät
FI935801L (fi) Imidatsoliyhdisteitä, niiden valmistus ja käyttö
FI944713L (fi) 4-difenyylimetyylipiperidiinijohdannaisia ja menetelmä niiden valmistamiseksi
FI942963L (fi) Imidatsokinatsoliiniyhdisteitä ja niiden valmistus ja käyttö
FI953021A0 (fi) 4-bentsoyyli-isoksatsolin johdannaisia ja niiden käyttö herbisideinä
ZA941926B (en) Heterocyclic compounds their preparation and use