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FI964482L - Amidijohdannaisia ja niiden käyttö lääkkeenä - Google Patents

Amidijohdannaisia ja niiden käyttö lääkkeenä Download PDF

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Publication number
FI964482L
FI964482L FI964482A FI964482A FI964482L FI 964482 L FI964482 L FI 964482L FI 964482 A FI964482 A FI 964482A FI 964482 A FI964482 A FI 964482A FI 964482 L FI964482 L FI 964482L
Authority
FI
Finland
Prior art keywords
medicine
amide derivatives
amide
derivatives
Prior art date
Application number
FI964482A
Other languages
English (en)
Swedish (sv)
Other versions
FI964482A0 (fi
Inventor
David Lee Musso
James Leroy Kelley
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of FI964482A0 publication Critical patent/FI964482A0/fi
Publication of FI964482L publication Critical patent/FI964482L/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C233/00Carboxylic acid amides
    • C07C233/01Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C233/02Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals
    • C07C233/11Carboxylic acid amides having carbon atoms of carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms having nitrogen atoms of carboxamide groups bound to hydrogen atoms or to carbon atoms of unsubstituted hydrocarbon radicals with carbon atoms of carboxamide groups bound to carbon atoms of an unsaturated carbon skeleton containing six-membered aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C17/00Preparation of halogenated hydrocarbons
    • C07C17/093Preparation of halogenated hydrocarbons by replacement by halogens
    • C07C17/10Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms
    • C07C17/14Preparation of halogenated hydrocarbons by replacement by halogens of hydrogen atoms in the side-chain of aromatic compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46Friedel-Crafts reactions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/58Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings
    • C07C57/60Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings having unsaturation outside the rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/52Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen
    • C07C57/62Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing halogen containing six-membered aromatic rings and other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/64Acyl halides
    • C07C57/76Acyl halides containing halogen outside the carbonyl halide groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/42Unsaturated compounds containing hydroxy or O-metal groups
    • C07C59/56Unsaturated compounds containing hydroxy or O-metal groups containing halogen
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/62Halogen-containing esters
    • C07C69/65Halogen-containing esters of unsaturated acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C69/00Esters of carboxylic acids; Esters of carbonic or haloformic acids
    • C07C69/66Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety
    • C07C69/73Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids
    • C07C69/732Esters of carboxylic acids having esterified carboxylic groups bound to acyclic carbon atoms and having any of the groups OH, O—metal, —CHO, keto, ether, acyloxy, groups, groups, or in the acid moiety of unsaturated acids of unsaturated hydroxy carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04One of the condensed rings being a six-membered aromatic ring
    • C07C2602/08One of the condensed rings being a six-membered aromatic ring the other ring being five-membered, e.g. indane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyrrole Compounds (AREA)
FI964482A 1994-05-10 1996-11-07 Amidijohdannaisia ja niiden käyttö lääkkeenä FI964482L (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP94303350 1994-05-10
PCT/GB1995/001040 WO1995030645A1 (en) 1994-05-10 1995-05-09 Amide derivatives and their therapeutic use

Publications (2)

Publication Number Publication Date
FI964482A0 FI964482A0 (fi) 1996-11-07
FI964482L true FI964482L (fi) 1996-11-07

Family

ID=8217701

Family Applications (1)

Application Number Title Priority Date Filing Date
FI964482A FI964482L (fi) 1994-05-10 1996-11-07 Amidijohdannaisia ja niiden käyttö lääkkeenä

Country Status (26)

Country Link
US (1) US5708033A (fi)
EP (1) EP0759026B1 (fi)
JP (1) JP3419462B2 (fi)
KR (1) KR100361788B1 (fi)
CN (1) CN1079788C (fi)
AT (1) ATE183496T1 (fi)
AU (1) AU702606B2 (fi)
BR (1) BR9507677A (fi)
CA (1) CA2190009A1 (fi)
DE (1) DE69511544T2 (fi)
DK (1) DK0759026T3 (fi)
ES (1) ES2134472T3 (fi)
FI (1) FI964482L (fi)
GR (1) GR3031458T3 (fi)
HK (1) HK1014532A1 (fi)
HU (1) HU219241B (fi)
IL (3) IL113665A (fi)
MX (1) MX9605458A (fi)
MY (1) MY113062A (fi)
NO (1) NO308654B1 (fi)
NZ (1) NZ285134A (fi)
RU (1) RU2145954C1 (fi)
SI (1) SI0759026T1 (fi)
TW (1) TW340109B (fi)
WO (1) WO1995030645A1 (fi)
ZA (1) ZA953753B (fi)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6391282B1 (en) * 1997-11-10 2002-05-21 Flemington Pharmaceutical Corp. Antihistamine sprays and ointments for relief of delayed contact dermatitis
DE19837069C1 (de) * 1998-08-17 2000-01-05 Bayer Ag Substituierte Zimtsäuren und Zimtsäureester, Verfahren zu ihrer Herstellung und ihre Verwendung zur Herstellung von substituierten Indanoncarbonsäureestern
US20040116405A1 (en) * 2001-02-06 2004-06-17 Brian Cox Use of bicyclic esters or amides for the treatment of diseases responsive to enhanced potassium channel activity
US6956129B2 (en) * 2001-02-16 2005-10-18 Bayer Aktiengesellschaft Polyhalogen-substituted cinnamic acids and cinnamic acid derivatives and a process for the preparation of polyhalogen-substituted cinnamic acids and cinnamic acid derivatives
PT1243262E (pt) * 2001-03-20 2006-10-31 Sanol Arznei Schwarz Gmbh Nova utilizacao de uma classe de compostos peptideos para o tratamento da dor inflamatoria nao neuropatica
DK1243263T3 (da) 2001-03-21 2003-03-17 Sanol Arznei Schwarz Gmbh Hidtil ukendt anvendelse af en klasse af peptidforbindelser til behandling af allodyni eller andre forskellige typer af kronisk- eller fantomsmerte
US20040048874A1 (en) * 2001-05-22 2004-03-11 Bardsley Hazel Judith New therapeutic use of 4-(2-fluorophenyl)-6-methyl-2-(1-piperazinyl)thieno[2,3-D]pyrimidine
GB0216027D0 (en) * 2002-07-10 2002-08-21 Arachnova Therapeutics Ltd New therapeutic use
MXPA05007381A (es) * 2003-01-13 2006-02-10 Dynogen Pharmaceuticals Inc Metodo para el tratamiento de transtornos funcionales del intestino.
AU2005232395B2 (en) 2004-04-16 2010-09-09 Schwarz Pharma Ag Use of peptidic compounds for the prophylaxis and treatment of chronic headache
NZ552651A (en) 2004-08-27 2010-07-30 Sanol Arznei Schwarz Gmbh Novel use of peptide compounds for treating bone cancer pain, chemotherapy-and nucleoside-induced pain
DE602006011952D1 (de) * 2005-12-20 2010-03-11 Nps Pharma Inc Fluorinierte verbindungen
CA2651679C (en) 2006-06-15 2017-01-03 Schwarz Pharma Ag Pharmaceutical composition with synergistic anticonvulsant effect
RU2522460C1 (ru) * 2013-01-09 2014-07-10 Федеральное государственное бюджетное учреждение высшего профессионального образования "Кемеровский государственный университет" (КемГУ) Способ получения алкенилантрахинонов

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE371190B (fi) * 1972-03-24 1974-11-11 Kabi Ab
US3325358A (en) * 1962-06-06 1967-06-13 Merck & Co Inc Method of treating inflammation
NO136750C (no) * 1972-06-19 1977-11-02 Takeda Chemical Industries Ltd Fremgangsm}te for fremstilling av indanderivater
JPS5623982B2 (fi) * 1972-12-07 1981-06-03
US5416118A (en) * 1992-04-09 1995-05-16 Schering Corporation Bicyclic amides as inhibitors of acyl-coenzyme A: cholesterol acyl transferase
GB9309621D0 (en) * 1993-05-11 1993-06-23 Wellcome Found Amide derivatives and their therapeutic use

Also Published As

Publication number Publication date
BR9507677A (pt) 1997-08-19
ES2134472T3 (es) 1999-10-01
MX9605458A (es) 1998-02-28
HK1014532A1 (en) 1999-09-30
AU702606B2 (en) 1999-02-25
GR3031458T3 (en) 2000-01-31
CA2190009A1 (en) 1995-11-16
DK0759026T3 (da) 2000-02-28
SI0759026T1 (en) 1999-10-31
EP0759026A1 (en) 1997-02-26
RU2145954C1 (ru) 2000-02-27
DE69511544T2 (de) 1999-12-23
IL113665A0 (en) 1995-08-31
WO1995030645A1 (en) 1995-11-16
MY113062A (en) 2001-11-30
DE69511544D1 (de) 1999-09-23
ATE183496T1 (de) 1999-09-15
NO308654B1 (no) 2000-10-09
US5708033A (en) 1998-01-13
HUT76465A (en) 1997-09-29
NO964750L (no) 1996-11-08
HU9603103D0 (en) 1997-01-28
FI964482A0 (fi) 1996-11-07
AU2413895A (en) 1995-11-29
TW340109B (en) 1998-09-11
EP0759026B1 (en) 1999-08-18
CN1153510A (zh) 1997-07-02
IL124966A (en) 1999-12-22
NO964750D0 (no) 1996-11-08
ZA953753B (en) 1996-11-11
NZ285134A (en) 1998-03-25
JP3419462B2 (ja) 2003-06-23
IL113665A (en) 1999-12-22
IL124966A0 (en) 1999-01-26
JPH09512814A (ja) 1997-12-22
CN1079788C (zh) 2002-02-27
KR100361788B1 (ko) 2003-01-24
HU219241B (en) 2001-03-28

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