FI942503A0 - Syövänvastaiset immunoterapeuttiset vektorikonstruktiot - Google Patents
Syövänvastaiset immunoterapeuttiset vektorikonstruktiotInfo
- Publication number
- FI942503A0 FI942503A0 FI942503A FI942503A FI942503A0 FI 942503 A0 FI942503 A0 FI 942503A0 FI 942503 A FI942503 A FI 942503A FI 942503 A FI942503 A FI 942503A FI 942503 A0 FI942503 A0 FI 942503A0
- Authority
- FI
- Finland
- Prior art keywords
- altered
- altered cellular
- expression
- vector constructs
- recombinant virus
- Prior art date
Links
- 230000001093 anti-cancer Effects 0.000 title 1
- 230000001024 immunotherapeutic effect Effects 0.000 title 1
- 241000700605 Viruses Species 0.000 abstract 3
- 230000001413 cellular effect Effects 0.000 abstract 3
- 210000004881 tumor cell Anatomy 0.000 abstract 2
- 102000044159 Ubiquitin Human genes 0.000 abstract 1
- 108090000848 Ubiquitin Proteins 0.000 abstract 1
- 108700025700 Wilms Tumor Genes Proteins 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 239000003085 diluting agent Substances 0.000 abstract 1
- 239000003937 drug carrier Substances 0.000 abstract 1
- 230000002163 immunogen Effects 0.000 abstract 1
- 231100001221 nontumorigenic Toxicity 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 108090000623 proteins and genes Proteins 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
- C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
- C07K14/4701—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used
- C07K14/4746—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals not used p53
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/82—Translation products from oncogenes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US80032891A | 1991-11-29 | 1991-11-29 | |
PCT/US1992/010309 WO1993010814A1 (en) | 1991-11-29 | 1992-11-30 | Anti-cancer immunotherapeutic vector constructs |
Publications (2)
Publication Number | Publication Date |
---|---|
FI942503A0 true FI942503A0 (fi) | 1994-05-27 |
FI942503L FI942503L (fi) | 1994-05-27 |
Family
ID=25178122
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI942503A FI942503L (fi) | 1991-11-29 | 1994-05-27 | Syövänvastaiset immunoterapeuttiset vektorikonstruktiot |
Country Status (10)
Country | Link |
---|---|
US (1) | US5693522A (fi) |
EP (1) | EP0615453B1 (fi) |
JP (1) | JPH07501942A (fi) |
AT (1) | ATE152915T1 (fi) |
AU (1) | AU671971B2 (fi) |
CA (1) | CA2117303C (fi) |
DE (1) | DE69219787T2 (fi) |
FI (1) | FI942503L (fi) |
NO (1) | NO941986L (fi) |
WO (1) | WO1993010814A1 (fi) |
Families Citing this family (59)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5662896A (en) * | 1988-03-21 | 1997-09-02 | Chiron Viagene, Inc. | Compositions and methods for cancer immunotherapy |
US5747469A (en) | 1991-03-06 | 1998-05-05 | Board Of Regents, The University Of Texas System | Methods and compositions comprising DNA damaging agents and p53 |
US20030086935A1 (en) * | 1992-07-22 | 2003-05-08 | Levine Arnold J. | p53 vaccine |
AU4788693A (en) * | 1992-07-22 | 1994-02-14 | Trustees Of Princeton University, The | P53 vaccine |
JPH08504095A (ja) * | 1992-09-18 | 1996-05-07 | カンジ,インコーポレイテッド | 腫瘍抑制遺伝子を有するレトロウイルスベクターによる遺伝子療法 |
US6953573B1 (en) * | 1993-03-17 | 2005-10-11 | University Of Washington | Compounds for eliciting or enhancing immune reactivity to HER-2/neu protein for prevention or treatment of malignancies in which the HER-2/neu oncogene is associated |
US5700657A (en) * | 1993-12-13 | 1997-12-23 | Genzyme Corporation | Vectors and vector systems including genes encoding tumor suppressor proteins and producer cells transformed thereby |
US5629192A (en) * | 1994-02-04 | 1997-05-13 | The United States Of America As Represented By The Department Of Health And Human Services | ETS1 gene: a human tumor suppressor gene |
AU697088B2 (en) * | 1994-04-29 | 1998-09-24 | Sidney Kimmel Cancer Center | Enhancing the sensitivity of tumor cells to therapies |
JP4303315B2 (ja) | 1994-05-09 | 2009-07-29 | オックスフォード バイオメディカ(ユーケー)リミテッド | 非交差性レトロウイルスベクター |
WO1997014426A1 (en) | 1995-10-20 | 1997-04-24 | University Of Nebraska Board Of Regents | Compositions and methods for enhancing immune responses mediated by antigen-presenting cells |
JP2002515734A (ja) * | 1996-01-02 | 2002-05-28 | カイロン コーポレイション | 遺伝子改変された樹状細胞により媒介される免疫刺激 |
US6365151B1 (en) * | 1996-01-19 | 2002-04-02 | Philadelphia Health And Educational Corporation | Cellular immunogens comprising cognate proto-oxogenes |
US6942862B2 (en) * | 1996-04-01 | 2005-09-13 | University Of Washington | Methods and compositions to generate immunity in humans against self tumor antigens by immunization with homologous foreign proteins |
AU2800797A (en) | 1996-04-05 | 1997-10-29 | Chiron Corporation | Recombinant alphavirus-based vectors with reduced inhibition of cellular macromolecular synthesis |
WO1998012332A1 (en) | 1996-09-17 | 1998-03-26 | Chiron Corporation | Compositions and methods for treating intracellular diseases |
US6884435B1 (en) * | 1997-01-30 | 2005-04-26 | Chiron Corporation | Microparticles with adsorbent surfaces, methods of making same, and uses thereof |
DK0991403T3 (da) * | 1997-01-30 | 2003-07-28 | Chiron Corp | Anvendelse af mikropartikler med adsorberet antigen til stimulering af immunresponser |
US20040202680A1 (en) * | 1997-01-30 | 2004-10-14 | O'hagan Derek | Microparticles with adsorbent surfaces, methods of making same, and uses thereof |
AU7486898A (en) | 1997-05-13 | 1998-12-08 | Stuart D Edwards | Global medical treatment method and apparatus |
FR2775601B1 (fr) * | 1998-03-03 | 2001-09-21 | Merial Sas | Vaccins vivants recombines et adjuves |
US6620382B1 (en) * | 1998-05-22 | 2003-09-16 | Biopheresis Technologies, Llc. | Method and compositions for treatment of cancers |
US7144581B2 (en) * | 2000-10-09 | 2006-12-05 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
US7329410B1 (en) | 1998-09-30 | 2008-02-12 | Corixa Corporation | Compositions and method for WT1 specific immunotherapy |
US7901693B2 (en) * | 1998-09-30 | 2011-03-08 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
US20030235557A1 (en) * | 1998-09-30 | 2003-12-25 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
US20030039635A1 (en) * | 1998-09-30 | 2003-02-27 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
US7115272B1 (en) | 1998-09-30 | 2006-10-03 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
US7063854B1 (en) * | 1998-09-30 | 2006-06-20 | Corixa Corporation | Composition and methods for WTI specific immunotherapy |
US7655249B2 (en) * | 1998-09-30 | 2010-02-02 | Corixa Corporation | Compositions and methods for WT1 specific immunotherapy |
US6787154B2 (en) * | 1998-10-20 | 2004-09-07 | Salvatore Albani | Artificial antigen presenting cells |
EP1123086B1 (en) | 1998-10-20 | 2010-03-03 | Androclus Technologies S.r.l. in liquidazione | Artificial antigen-specific cells and related methods |
US7807377B2 (en) | 1998-10-20 | 2010-10-05 | Salvatore Albani | Method of isolating antigen-specific T cells employing artificial antigen presenting cells |
GB9907414D0 (en) | 1999-03-31 | 1999-05-26 | Cancer Res Campaign Tech | Improvements relating to prodrugs |
US8647864B2 (en) | 1999-04-14 | 2014-02-11 | Novartis Ag | Compositions and methods for generating an immune response utilizing alphavirus-based vector systems |
US7049410B2 (en) * | 1999-05-14 | 2006-05-23 | Majumdar Adhip P N | Antibodies to a novel EGF-receptor related protein (ERRP) |
US6399743B1 (en) | 1999-05-14 | 2002-06-04 | Dept. Of Veterans Affairs | Isolation and characterization of a rat epidermal growth factor related protein |
AU6944100A (en) * | 1999-09-01 | 2001-03-26 | Johns Hopkins University, The | Beta-catenin, tcf-4, and apc interact to prevent cancer |
US6432409B1 (en) | 1999-09-14 | 2002-08-13 | Antigen Express, Inc. | Hybrid peptides modulate the immune response |
US20030235594A1 (en) * | 1999-09-14 | 2003-12-25 | Antigen Express, Inc. | Ii-Key/antigenic epitope hybrid peptide vaccines |
US9289487B2 (en) * | 1999-09-14 | 2016-03-22 | Antigen Express, Inc. | II-key/antigenic epitope hybrid peptide vaccines |
US6656718B2 (en) | 2000-07-07 | 2003-12-02 | Cancer Research Technology Limited | Modified carboxypeptidase enzymes and their use |
US7919467B2 (en) | 2000-12-04 | 2011-04-05 | Immunotope, Inc. | Cytotoxic T-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer |
US7083789B2 (en) | 2000-12-04 | 2006-08-01 | Immunotope, Inc. | Cytotoxic T-lymphocyte-inducing immunogens for prevention, treatment, and diagnosis of cancer |
WO2002099035A2 (en) | 2001-05-31 | 2002-12-12 | Chiron Corporation | Chimeric alphavirus replicon particles |
US7553494B2 (en) | 2001-08-24 | 2009-06-30 | Corixa Corporation | WT1 fusion proteins |
WO2004030616A2 (en) | 2002-09-17 | 2004-04-15 | Antigen Express, Inc. | Ii-KEY/ANTIGENIC EPITOPE HYBRID PEPTIDE VACCINES |
US7179645B2 (en) * | 2002-09-24 | 2007-02-20 | Antigen Express, Inc. | Ii-Key/antigenic epitope hybrid peptide vaccines |
WO2005087260A1 (en) * | 2004-03-04 | 2005-09-22 | Corixa Corporation | Co-encapsulated wt1 polypeptide and immunostimulant microsphere formulations and methods thereof |
EP1768662A2 (en) | 2004-06-24 | 2007-04-04 | Novartis Vaccines and Diagnostics, Inc. | Small molecule immunopotentiators and assays for their detection |
CA2571421A1 (en) | 2004-06-24 | 2006-01-05 | Nicholas Valiante | Compounds for immunopotentiation |
JP2009511636A (ja) | 2005-10-18 | 2009-03-19 | ノバルティス ヴァクシンズ アンド ダイアグノスティクス, インコーポレイテッド | アルファウイルスレプリコン粒子による粘膜免疫および全身免疫 |
CA2647100A1 (en) * | 2006-03-23 | 2007-09-27 | Novartis Ag | Methods for the preparation of imidazole-containing compounds |
ES2388556T3 (es) * | 2006-03-23 | 2012-10-16 | Novartis Ag | Compuestos inmunopotenciadores |
ES2376492T3 (es) | 2006-03-23 | 2012-03-14 | Novartis Ag | Compuestos de imidazoquinoxalina como inmunomoduladores. |
CA3116266A1 (en) * | 2008-01-28 | 2009-08-06 | Implantica Patent Ltd. | Blood clot removal device, system, and method |
EP2391748A4 (en) * | 2009-01-28 | 2012-08-01 | Antigen Express Inc | LI-KEY HYBRID PEPTIDES MODULATING IMMUNE RESPONSE TO FLU |
WO2011149564A1 (en) | 2010-05-28 | 2011-12-01 | Tetris Online, Inc. | Interactive hybrid asynchronous computer game infrastructure |
EP3405212B1 (en) | 2016-01-19 | 2020-07-08 | Pfizer Inc | Cancer vaccines |
Family Cites Families (18)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4405712A (en) * | 1981-07-01 | 1983-09-20 | The United States Of America As Represented By The Department Of Health And Human Services | LTR-Vectors |
US4965196A (en) * | 1983-01-19 | 1990-10-23 | Genentech, Inc. | Polycistronic expression vector construction |
GB8424757D0 (en) * | 1984-10-01 | 1984-11-07 | Pasteur Institut | Retroviral vector |
US4797368A (en) * | 1985-03-15 | 1989-01-10 | The United States Of America As Represented By The Department Of Health And Human Services | Adeno-associated virus as eukaryotic expression vector |
US4871838A (en) * | 1985-07-23 | 1989-10-03 | The Board Of Rijks Universiteit Leiden | Probes and methods for detecting activated ras oncogenes |
US4931275A (en) * | 1985-12-02 | 1990-06-05 | Yeda Research & Development Co., Ltd. | Anti-tumor vaccines and their preparation |
CA1310924C (en) * | 1986-04-24 | 1992-12-01 | Francis P. Mccormick | Infective drug delivery system |
US4861719A (en) * | 1986-04-25 | 1989-08-29 | Fred Hutchinson Cancer Research Center | DNA constructs for retrovirus packaging cell lines |
US4980289A (en) * | 1987-04-27 | 1990-12-25 | Wisconsin Alumni Research Foundation | Promoter deficient retroviral vector |
EP0293181B1 (en) * | 1987-05-29 | 1995-08-16 | Dana Farber Cancer Institute | Cis-acting repression sequences, cis-acting anti-repression sequences, vectors, methods of preparation and use |
WO1989001973A2 (en) * | 1987-09-02 | 1989-03-09 | Applied Biotechnology, Inc. | Recombinant pox virus for immunization against tumor-associated antigens |
WO1989002468A1 (en) * | 1987-09-11 | 1989-03-23 | Whitehead Institute For Biomedical Research | Transduced fibroblasts and uses therefor |
WO1989005349A1 (en) * | 1987-12-09 | 1989-06-15 | The Australian National University | Method of combating viral infections |
US4957859A (en) * | 1988-02-16 | 1990-09-18 | Hoffmann-La Roche Inc. | Antibodies for transforming ras protein |
JP3082204B2 (ja) * | 1988-09-01 | 2000-08-28 | ホワイトヘッド・インスティチュート・フォー・バイオメディカル・リサーチ | 両栄養性および環境栄養性宿主域を持つ組換え体レトロウイルス |
CA2357538A1 (en) * | 1989-03-21 | 1990-10-04 | Wisconsin Alumni Research Foundation | Expression of exogenous polynucleotide sequences in a vertebrate |
ES2106033T3 (es) * | 1989-05-19 | 1997-11-01 | Genentech Inc | Dominio extracelular de her2. |
FR2668064B1 (fr) * | 1990-10-23 | 1994-12-16 | Transgene Sa | Composition pharmaceutique pour le traitement ou la prevention d'une tumeur maligne. |
-
1992
- 1992-11-30 EP EP93900751A patent/EP0615453B1/en not_active Expired - Lifetime
- 1992-11-30 AT AT93900751T patent/ATE152915T1/de not_active IP Right Cessation
- 1992-11-30 JP JP5510289A patent/JPH07501942A/ja active Pending
- 1992-11-30 AU AU32297/93A patent/AU671971B2/en not_active Ceased
- 1992-11-30 DE DE69219787T patent/DE69219787T2/de not_active Expired - Fee Related
- 1992-11-30 CA CA002117303A patent/CA2117303C/en not_active Expired - Fee Related
- 1992-11-30 WO PCT/US1992/010309 patent/WO1993010814A1/en active IP Right Grant
-
1994
- 1994-05-27 NO NO941986A patent/NO941986L/no unknown
- 1994-05-27 FI FI942503A patent/FI942503L/fi unknown
-
1995
- 1995-01-11 US US08/371,922 patent/US5693522A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AU671971B2 (en) | 1996-09-19 |
US5693522A (en) | 1997-12-02 |
CA2117303A1 (en) | 1993-06-10 |
FI942503L (fi) | 1994-05-27 |
NO941986L (no) | 1994-07-27 |
DE69219787T2 (de) | 1997-08-28 |
JPH07501942A (ja) | 1995-03-02 |
AU3229793A (en) | 1993-06-28 |
EP0615453A1 (en) | 1994-09-21 |
DE69219787D1 (de) | 1997-06-19 |
CA2117303C (en) | 2000-10-17 |
WO1993010814A1 (en) | 1993-06-10 |
NO941986D0 (no) | 1994-05-27 |
EP0615453B1 (en) | 1997-05-14 |
ATE152915T1 (de) | 1997-05-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
GB | Transfer or assigment of application |
Owner name: CHIRON VIAGENE, INC. |