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FI810876L - Expression av polypeptider i bakterier genom promotor/operatorn av tryptofangenen - Google Patents

Expression av polypeptider i bakterier genom promotor/operatorn av tryptofangenen

Info

Publication number
FI810876L
FI810876L FI810876A FI810876A FI810876L FI 810876 L FI810876 L FI 810876L FI 810876 A FI810876 A FI 810876A FI 810876 A FI810876 A FI 810876A FI 810876 L FI810876 L FI 810876L
Authority
FI
Finland
Prior art keywords
tryptofangenen
bakterier
polypeptider
genom
promotor
Prior art date
Application number
FI810876A
Other languages
English (en)
Inventor
Dennis G Kleid
Daniel G Yansura
Herbert L Heyneker
Giuseppe F Miozzari
Original Assignee
Genentech Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genentech Inc filed Critical Genentech Inc
Publication of FI810876L publication Critical patent/FI810876L/fi
Priority to FI853488A priority Critical patent/FI853488L/fi
Priority to FI853489A priority patent/FI72344C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/10—Processes for the isolation, preparation or purification of DNA or RNA
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/61—Growth hormone [GH], i.e. somatotropin
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/62—DNA sequences coding for fusion proteins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/71—Expression systems using regulatory sequences derived from the trp-operon
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/26—Preparation of nitrogen-containing carbohydrates
    • C12P19/28—N-glycosides
    • C12P19/30—Nucleotides
    • C12P19/34—Polynucleotides, e.g. nucleic acids, oligoribonucleotides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Microbiology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Endocrinology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Medicinal Chemistry (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
FI810876A 1980-03-24 1981-03-20 Expression av polypeptider i bakterier genom promotor/operatorn av tryptofangenen FI810876L (fi)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FI853488A FI853488L (fi) 1980-03-24 1985-09-12 Foerfarande foer framstaellning av en expressionsplasmid.
FI853489A FI72344C (fi) 1980-03-24 1985-09-12 Foerfarande foer spjaelkning av dubbelstraengat dna.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US13329680A 1980-03-24 1980-03-24

Publications (1)

Publication Number Publication Date
FI810876L true FI810876L (fi) 1981-09-25

Family

ID=22457906

Family Applications (3)

Application Number Title Priority Date Filing Date
FI810876A FI810876L (fi) 1980-03-24 1981-03-20 Expression av polypeptider i bakterier genom promotor/operatorn av tryptofangenen
FI853489A FI72344C (fi) 1980-03-24 1985-09-12 Foerfarande foer spjaelkning av dubbelstraengat dna.
FI853488A FI853488L (fi) 1980-03-24 1985-09-12 Foerfarande foer framstaellning av en expressionsplasmid.

Family Applications After (2)

Application Number Title Priority Date Filing Date
FI853489A FI72344C (fi) 1980-03-24 1985-09-12 Foerfarande foer spjaelkning av dubbelstraengat dna.
FI853488A FI853488L (fi) 1980-03-24 1985-09-12 Foerfarande foer framstaellning av en expressionsplasmid.

Country Status (35)

Country Link
US (2) US5888808A (fi)
EP (3) EP0154133B1 (fi)
JP (3) JPH0724582B2 (fi)
KR (2) KR830005351A (fi)
AR (1) AR248050A1 (fi)
AT (3) ATE27306T1 (fi)
AU (3) AU542640B2 (fi)
BG (3) BG46005A3 (fi)
BR (1) BR8101712A (fi)
CA (2) CA1198068A (fi)
CS (3) CS238645B2 (fi)
DD (3) DD203746A5 (fi)
DE (5) DE3177179D1 (fi)
DK (1) DK173085B1 (fi)
DZ (1) DZ278A1 (fi)
ES (3) ES500617A0 (fi)
FI (3) FI810876L (fi)
FR (2) FR2480781B1 (fi)
GB (1) GB2073203B (fi)
GR (1) GR74818B (fi)
HU (1) HU195534B (fi)
IE (3) IE51894B1 (fi)
IL (3) IL71885A (fi)
IT (1) IT1144324B (fi)
MX (1) MX7689E (fi)
MY (1) MY8500896A (fi)
NO (3) NO810986L (fi)
NZ (3) NZ196584A (fi)
OA (1) OA06774A (fi)
PH (4) PH17537A (fi)
PL (2) PL162227B1 (fi)
PT (1) PT72716B (fi)
YU (2) YU45534B (fi)
ZA (1) ZA811368B (fi)
ZW (1) ZW5481A1 (fi)

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YU45534B (en) 1992-05-28
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