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ES2103136T3 - Kit de ensayo. - Google Patents

Kit de ensayo.

Info

Publication number
ES2103136T3
ES2103136T3 ES94927577T ES94927577T ES2103136T3 ES 2103136 T3 ES2103136 T3 ES 2103136T3 ES 94927577 T ES94927577 T ES 94927577T ES 94927577 T ES94927577 T ES 94927577T ES 2103136 T3 ES2103136 T3 ES 2103136T3
Authority
ES
Spain
Prior art keywords
link
suin
competitor
test
test kit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES94927577T
Other languages
English (en)
Inventor
Francois Legay
Roland Wenger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Novartis AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG, Novartis AG filed Critical Ciba Geigy AG
Application granted granted Critical
Publication of ES2103136T3 publication Critical patent/ES2103136T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9493Immunosupressants

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Peptides Or Proteins (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Measurement Of The Respiration, Hearing Ability, Form, And Blood Characteristics Of Living Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Input Circuits Of Receivers And Coupling Of Receivers And Audio Equipment (AREA)
  • Fishing Rods (AREA)
  • Control Of Motors That Do Not Use Commutators (AREA)
  • Investigation Of Foundation Soil And Reinforcement Of Foundation Soil By Compacting Or Drainage (AREA)
  • Sanitary Device For Flush Toilet (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)

Abstract

SE PROPORCIONA UN NUEVO METODO DE MEDIDA DE LOS NIVELES DE SANGRE DE COMPUESTOS FARMACEUTICOS DE ENLACE DE INMUNOFILINA, POR EJEMPLO, CICLOSPORINAS, RAPAMICINAS, Y FK506, QUE COMPRENDE EL NUEVO PASO DE DESPLAZAR EL FARMACO DE SU INMUNOFILINA MEDIANTE LA UTILIZACION DE UN COMPETIDOR DE ENLACE, ELIMINANDO DE ESTA MANERA LA NECESIDAD DE UN PASO DE EXTRACCION Y AUMENTANDO LA SIMPLICIDAD Y EXACTITUD DEL ENSAYO. SE PROPORCIONAN TAMBIEN CONJUNTOS DE ENSAYO QUE COMPRENDEN UN COMPETIDOR Y UN RECEPTOR DE ENLACE, POR EJEMPLO, UN ANTICUERPO MONOCLONAL, QUE ENLAZA CON EL FARMACO PERO NO SIGNIFICATIVAMENTE CON EL COMPETIDOR DE ENLACE, COMO SON NUEVAS UTILIZACIONES DE COMPUESTOS DE ENLACE DE INMUNOFILINA COMO COMPETIDORES DE ENLACE EN TALES ENSAYOS.
ES94927577T 1993-09-08 1994-09-07 Kit de ensayo. Expired - Lifetime ES2103136T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939318612A GB9318612D0 (en) 1993-09-08 1993-09-08 An assay

Publications (1)

Publication Number Publication Date
ES2103136T3 true ES2103136T3 (es) 1997-08-16

Family

ID=10741695

Family Applications (1)

Application Number Title Priority Date Filing Date
ES94927577T Expired - Lifetime ES2103136T3 (es) 1993-09-08 1994-09-07 Kit de ensayo.

Country Status (23)

Country Link
EP (1) EP0717850B1 (es)
JP (1) JP2892503B2 (es)
KR (1) KR100313841B1 (es)
CN (1) CN1088196C (es)
AT (1) ATE153769T1 (es)
AU (1) AU680946B2 (es)
BR (1) BR9407422A (es)
CA (1) CA2169162C (es)
CZ (1) CZ289434B6 (es)
DE (1) DE69403484T2 (es)
DK (1) DK0717850T3 (es)
ES (1) ES2103136T3 (es)
FI (1) FI111035B (es)
GB (1) GB9318612D0 (es)
GR (1) GR3023578T3 (es)
HK (1) HK1005754A1 (es)
HU (1) HU218743B (es)
NO (1) NO960924D0 (es)
NZ (1) NZ273595A (es)
PL (1) PL176727B1 (es)
RU (1) RU2138052C1 (es)
SK (1) SK281369B6 (es)
WO (1) WO1995007468A1 (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6187757B1 (en) 1995-06-07 2001-02-13 Ariad Pharmaceuticals, Inc. Regulation of biological events using novel compounds
US5650288A (en) * 1995-07-14 1997-07-22 Macfarlane; Gordon D. Immunophilin-bound immunosuppressant assay
EP0944394A4 (en) * 1996-03-12 2003-05-14 Picower Inst Med Res TREATING HIV INFECTION BY INFLUENCING CYCLOPHILIN RECEPTOR ACTIVITY IN THE HOST CELL
US6106779A (en) * 1997-10-02 2000-08-22 Biosite Diagnostics, Inc. Lysis chamber for use in an assay device
US7067526B1 (en) 1999-08-24 2006-06-27 Ariad Gene Therapeutics, Inc. 28-epirapalogs
ATE264863T1 (de) 1999-08-24 2004-05-15 Ariad Gene Therapeutics Inc 28-epirapaloge
AU2003300076C1 (en) 2002-12-30 2010-03-04 Angiotech International Ag Drug delivery from rapid gelling polymer composition
US7186518B2 (en) 2003-11-21 2007-03-06 Dade Behring Inc. Method and composition useful for determining FK 506
EP1768662A2 (en) 2004-06-24 2007-04-04 Novartis Vaccines and Diagnostics, Inc. Small molecule immunopotentiators and assays for their detection
AU2006259348B2 (en) 2005-06-17 2010-07-22 Novartis Ag Use of sanglifehrin in HCV
CN100434901C (zh) * 2006-01-12 2008-11-19 上海交通大学 血红蛋白凝胶层析的教学试剂盒
US7914999B2 (en) * 2006-12-29 2011-03-29 Abbott Laboratories Non-denaturing lysis reagent
US7790401B2 (en) * 2007-08-06 2010-09-07 Siemens Healthcare Diagnostics Methods for detection of immunosuppressant drugs
WO2009089549A1 (en) 2008-01-11 2009-07-16 Massachusetts Eye & Ear Infirmary Conditional-stop dimerizable caspase transgenic animals
US9658218B2 (en) * 2012-05-07 2017-05-23 Siemens Healthcare Diagnostics Inc. Determination of total analyte concentration
US9121859B2 (en) * 2012-12-04 2015-09-01 Siemens Healthcare Diagnostics Inc. Compounds and methods for determination of FKBP-binding immunosuppressant drugs
CN105283553B (zh) 2013-06-11 2021-06-25 克隆技术实验室有限公司 蛋白质富集的微泡及其制备和使用方法
KR101760707B1 (ko) 2015-01-05 2017-07-24 한림대학교 산학협력단 이종 알부민을 이용한 장기 이식 거부반응 검사용 키트
CN104749009B (zh) * 2015-03-30 2018-05-04 上海云泽生物科技有限公司 用于免疫分析的免疫抑制剂药物提取试剂
CN104764883A (zh) * 2015-03-31 2015-07-08 上海云泽生物科技有限公司 一种检测环孢霉素a浓度的免疫分析方法和试剂盒
WO2020092153A1 (en) * 2018-11-02 2020-05-07 Siemens Healthcare Diagnostics Inc. Binding competitors for use in macrophilin-binding pharmaceutical assays and methods of use thereof

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES2060621T3 (es) * 1987-06-05 1994-12-01 Fujisawa Pharmaceutical Co Anticuerpos anti-sustancia fr-900506 y metodo de inmunoensayo enzimatico altamente sensible.
DE3884470T2 (de) * 1987-06-17 1994-03-10 Sandoz Ag Cyclosporine und deren Benutzung als Arzneimittel.
US5322772A (en) * 1991-04-09 1994-06-21 Children's Research Institute Rapamycin assay
AU4400593A (en) * 1992-06-05 1994-01-04 Abbott Laboratories Methods and reagents for the determination of immunosuppressive agents
GB9307491D0 (en) * 1993-04-08 1993-06-02 Sandoz Ltd Organic compounds

Also Published As

Publication number Publication date
PL313392A1 (en) 1996-06-24
JP2892503B2 (ja) 1999-05-17
SK31096A3 (en) 1996-07-03
FI961004A0 (fi) 1996-03-04
HU9600564D0 (en) 1996-05-28
ATE153769T1 (de) 1997-06-15
BR9407422A (pt) 1996-04-09
JPH09502272A (ja) 1997-03-04
CA2169162C (en) 2004-02-03
NO960924L (no) 1996-03-07
DK0717850T3 (da) 1997-10-20
SK281369B6 (sk) 2001-02-12
DE69403484T2 (de) 1997-12-04
EP0717850B1 (en) 1997-05-28
CN1088196C (zh) 2002-07-24
FI961004L (fi) 1996-03-04
NZ273595A (en) 1996-08-27
AU680946B2 (en) 1997-08-14
HU218743B (hu) 2000-11-28
PL176727B1 (pl) 1999-07-30
EP0717850A1 (en) 1996-06-26
FI111035B (fi) 2003-05-15
CZ66296A3 (en) 1996-09-11
RU2138052C1 (ru) 1999-09-20
AU7694894A (en) 1995-03-27
CA2169162A1 (en) 1995-03-16
NO960924D0 (no) 1996-03-07
KR100313841B1 (ko) 2001-12-28
HUT73692A (en) 1996-09-30
CZ289434B6 (cs) 2002-01-16
GR3023578T3 (en) 1997-08-29
WO1995007468A1 (en) 1995-03-16
CN1130425A (zh) 1996-09-04
HK1005754A1 (en) 1999-01-22
DE69403484D1 (de) 1997-07-03
GB9318612D0 (en) 1993-10-27

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