[go: up one dir, main page]

AU4400593A - Methods and reagents for the determination of immunosuppressive agents - Google Patents

Methods and reagents for the determination of immunosuppressive agents

Info

Publication number
AU4400593A
AU4400593A AU44005/93A AU4400593A AU4400593A AU 4400593 A AU4400593 A AU 4400593A AU 44005/93 A AU44005/93 A AU 44005/93A AU 4400593 A AU4400593 A AU 4400593A AU 4400593 A AU4400593 A AU 4400593A
Authority
AU
Australia
Prior art keywords
reagents
determination
methods
immunosuppressive agents
immunosuppressive
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU44005/93A
Inventor
Timothy J Bolling
Benjamin Clay Lane
Jay Richard Luly
Wldozimierz Mandecki
Tami J. Pilot-Matias
Allan H Smith
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Abbott Laboratories
Original Assignee
Abbott Laboratories
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Abbott Laboratories filed Critical Abbott Laboratories
Publication of AU4400593A publication Critical patent/AU4400593A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D498/18—Bridged systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/715—Receptors; Cell surface antigens; Cell surface determinants for cytokines; for lymphokines; for interferons
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/12—Transferases (2.) transferring phosphorus containing groups, e.g. kinases (2.7)
    • C12N9/1241—Nucleotidyltransferases (2.7.7)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/32—Fusion polypeptide fusions with soluble part of a cell surface receptor, "decoy receptors"
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/61—Fusion polypeptide containing an enzyme fusion for detection (lacZ, luciferase)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Cell Biology (AREA)
  • Immunology (AREA)
  • Toxicology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU44005/93A 1992-06-05 1993-06-01 Methods and reagents for the determination of immunosuppressive agents Abandoned AU4400593A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US89385892A 1992-06-05 1992-06-05
US893858 1992-06-05
PCT/US1993/005197 WO1993025533A1 (en) 1992-06-05 1993-06-01 Methods and reagents for the determination of immunosuppressive agents

Publications (1)

Publication Number Publication Date
AU4400593A true AU4400593A (en) 1994-01-04

Family

ID=25402239

Family Applications (1)

Application Number Title Priority Date Filing Date
AU44005/93A Abandoned AU4400593A (en) 1992-06-05 1993-06-01 Methods and reagents for the determination of immunosuppressive agents

Country Status (2)

Country Link
AU (1) AU4400593A (en)
WO (1) WO1993025533A1 (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU680946B2 (en) * 1993-09-08 1997-08-14 Novartis Ag Assay kit

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6063625A (en) * 1993-02-12 2000-05-16 Board Of Trustees Of Leland S, Stanford, Jr. University Regulated transcription of targeted genes and other biological events
US5869337A (en) * 1993-02-12 1999-02-09 President And Fellows Of Harvard College Regulated transcription of targeted genes and other biological events
US5834266A (en) 1993-02-12 1998-11-10 President & Fellows Of Harvard College Regulated apoptosis
US6972193B1 (en) 1993-02-12 2005-12-06 Board Of Trustees Of Leland Stanford Junior University Regulated transcription of targeted genes and other biological events
US6891021B2 (en) 1993-02-12 2005-05-10 Board Of Trustees Of The Leland Stanford Junior University Regulated apoptosis
US5830462A (en) * 1993-02-12 1998-11-03 President & Fellows Of Harvard College Regulated transcription of targeted genes and other biological events
US7279561B1 (en) 1993-04-23 2007-10-09 Wyeth Anti-rapamycin monoclonal antibodies
DE69430060T2 (en) 1993-04-23 2002-11-07 Abbott Laboratories, Abbott Park RAPAMYCINE ANTIBODIES WITH OPEN RING
US5504091A (en) * 1993-04-23 1996-04-02 American Home Products Corporation Biotin esters of rapamycin
WO1994025072A1 (en) * 1993-04-23 1994-11-10 American Home Products Corporation Rapamycin conjugates and antibodies
US5482850A (en) * 1993-10-29 1996-01-09 New England Biolabs, Inc. Method for identifying anti-parasitic compounds
IL112873A (en) 1994-03-08 2005-03-20 Wyeth Corp Rapamycin-fkbp12 binding proteins, their isolation and their use
WO1996012018A2 (en) * 1994-10-14 1996-04-25 The Salk Institute For Biological Studies Novel immunophilins and corresponding nucleic acids
US5635406A (en) * 1995-06-07 1997-06-03 Abbott Laboratories Stabilized standards and calibrators containing rapamycin and tacrolimus bound to anti-rapamycin and anti-tacrolimus antibodies
US6187757B1 (en) 1995-06-07 2001-02-13 Ariad Pharmaceuticals, Inc. Regulation of biological events using novel compounds
JP2001518784A (en) * 1997-04-09 2001-10-16 アイソテクニカ，インコーポレイテッド Method for producing antibody against specific site of rapamycin
US6709873B1 (en) 1997-04-09 2004-03-23 Isodiagnostika Inc. Method for production of antibodies to specific sites of rapamycin
US20030220234A1 (en) 1998-11-02 2003-11-27 Selvaraj Naicker Deuterated cyclosporine analogs and their use as immunodulating agents
US7067526B1 (en) 1999-08-24 2006-06-27 Ariad Gene Therapeutics, Inc. 28-epirapalogs
ATE264863T1 (en) 1999-08-24 2004-05-15 Ariad Gene Therapeutics Inc 28-EPIRAPALOGUE
US6962982B2 (en) 2001-06-22 2005-11-08 Roche Diagnostics Corporation Soluble complexes of target proteins and peptidyl prolyl isomerase chaperones and methods of making and using them
EP2267452B8 (en) 2001-06-22 2012-11-14 Roche Diagnostics GmbH A soluble complex comprising a retroviral surface glycoprotein
US7094757B2 (en) 2001-06-22 2006-08-22 Roche Diagnostics Corporation Complexes comprising a prion protein and a peptidyl prolyl isomerase chaperone, and method for producing and using them
FI116198B (en) * 2001-07-16 2005-10-14 Valtion Teknillinen A method for immobilizing polypeptides
MXPA04003625A (en) 2001-10-19 2004-12-02 Sotechnika Inc Synthesis of cyclosporin analogs.
EP1594459B1 (en) 2002-12-30 2010-02-17 Angiotech International Ag Drug delivery from rapid gelling polymer composition
US7189582B2 (en) 2005-04-27 2007-03-13 Dade Behring Inc. Compositions and methods for detection of sirolimus
US7642338B2 (en) 2006-06-20 2010-01-05 Siemens Healthcare Diagnostics Inc. Tacrolimus standard and methods of using same
US7883855B2 (en) 2006-07-21 2011-02-08 Abbott Laboratories Immunosuppressant drug extraction reagent for immunoassays
US7914999B2 (en) 2006-12-29 2011-03-29 Abbott Laboratories Non-denaturing lysis reagent
CA2673314C (en) 2006-12-29 2014-03-11 Abbott Laboratories Non-denaturing lysis reagent for use with capture-in-solution immunoassay
CA2672972C (en) 2006-12-29 2015-06-23 Abbott Laboratories Diagnostic test for the detection of a molecule or drug in whole blood
WO2008082982A1 (en) 2006-12-29 2008-07-10 Abbott Laboratories Improved assay for immunosuppressant drugs
CA2711765A1 (en) 2008-01-11 2009-07-16 Massachusetts Eye & Ear Infirmary Conditional-stop dimerizable caspase transgenic animals
US9487480B2 (en) 2010-05-21 2016-11-08 Siemens Healthcare Diagnostics Inc. Zwitterionic reagents
CN105283553B (en) 2013-06-11 2021-06-25 克隆技术实验室有限公司 Protein-enriched microvesicles and methods of making and using the same
CN104749009B (en) * 2015-03-30 2018-05-04 上海云泽生物科技有限公司 immunosuppressant drug extraction reagent for immunoassay

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4894366A (en) * 1984-12-03 1990-01-16 Fujisawa Pharmaceutical Company, Ltd. Tricyclo compounds, a process for their production and a pharmaceutical composition containing the same
US5047512A (en) * 1985-05-03 1991-09-10 Handschumacher Robert E Immobilized cyclophilin and methods of using such
EP0293892B1 (en) * 1987-06-05 1993-12-15 Fujisawa Pharmaceutical Co., Ltd. Anti-FR-900506 substance antibodies and highly-sensitive enzyme immunoassay method
US5124255A (en) * 1988-03-11 1992-06-23 Abbott Laboratories CKS method of protein synthesis
US5109112A (en) * 1989-01-19 1992-04-28 Merck & Co., Inc. FK-506 cytosolic binding protein
US5196352A (en) * 1989-01-19 1993-03-23 Merck & Co., Inc. New FK-506 cytosolic binding protein
WO1991017439A1 (en) * 1990-05-09 1991-11-14 Children's Research Institute Receptor assay for fk-506

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU680946B2 (en) * 1993-09-08 1997-08-14 Novartis Ag Assay kit

Also Published As

Publication number Publication date
WO1993025533A1 (en) 1993-12-23

Similar Documents

Publication Publication Date Title
AU4400593A (en) Methods and reagents for the determination of immunosuppressive agents
AU628269B2 (en) Method and device for the assay of ions
AU7098094A (en) Methods and materials for modulation of the immunosuppressive activity and toxicity of monoclonal antibodies
AU2597995A (en) Reagents and methods for the rapid and quantitative assay of pharmacological agents
AU3508993A (en) Analysis of particle characteristics
AU2787892A (en) Highly reactive forms of zinc and reagents thereof
AU1322195A (en) Method of assay
AU666605B2 (en) Reagent for endotoxin assay and method for endotoxin assay using the same
AU4535893A (en) Screening assay for the identification of immunosuppressive drugs
AU5734294A (en) Construction geometry using dof analysis
AU4930993A (en) Coupled replication-translation methods and kits for protein synthesis
AU5016793A (en) Dual functional anti-inflammatory and immunosuppressive agents
AU1186695A (en) Reagents and methods for the detection of methotrexate
AU3697393A (en) Method for the elimination of non-specific reactions in immunoassays
AU679274B2 (en) Reduction of background interferences in the molybdate-dye protein assay
AU3385693A (en) Determination method
AU6254694A (en) Novel macrocomposite bodies and methods for making the same
AU6104994A (en) Apparatus for the quantitative determination of particulate analytes
AU7858691A (en) Plaque-inhibiting protein from bacteroides loeschei and methods for using the same
EP0608117A3 (en) Antibodies for mevalonic acid and methods for determination of mevalonic acid.
AU7677194A (en) Sulfamethoxazole-specific immunosuppressive agents
AU5002196A (en) Immunosuppressive agents
AU7852791A (en) Assay method for mutagenic agents and kit
AU5425194A (en) Detection of anti-hpa antibodies
AU6969096A (en) Monoclonal lymphocytes and methods of use