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EA031209B9 - Фармацевтический состав антитела для лечения воспалительного заболевания и способы его применения - Google Patents

Фармацевтический состав антитела для лечения воспалительного заболевания и способы его применения

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Publication number
EA031209B9
EA031209B9 EA201290653A EA201290653A EA031209B9 EA 031209 B9 EA031209 B9 EA 031209B9 EA 201290653 A EA201290653 A EA 201290653A EA 201290653 A EA201290653 A EA 201290653A EA 031209 B9 EA031209 B9 EA 031209B9
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EA
Eurasian Patent Office
Prior art keywords
treating
methods
formulation
inflammatory disease
pharmaceutical formulation
Prior art date
Application number
EA201290653A
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English (en)
Other versions
EA031209B1 (ru
EA201290653A1 (ru
Inventor
Динцзян Лю
Холли Чжохун Хуан
Дэвид Эндрю Мартин
Кристофер Бойд Расселл
Дэвид Х. Салинджер
Скотт Уолтер Баумгартнер
Кристофер Дж. Эндрес
Original Assignee
Кирин-Эмджен, Инк.
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First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=43858045&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=EA031209(B9) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Кирин-Эмджен, Инк. filed Critical Кирин-Эмджен, Инк.
Publication of EA201290653A1 publication Critical patent/EA201290653A1/ru
Publication of EA031209B1 publication Critical patent/EA031209B1/ru
Publication of EA031209B9 publication Critical patent/EA031209B9/ru

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    • A61K39/39591—Stabilisation, fragmentation
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    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
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    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
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Abstract

Изобретение относится к фармацевтическому составу для лечения воспалительного заболевания, такого как псориаз, псориатический артрит, астму, анкилозирующий спондилит или рассеянный склероз. Указанный состав содержит водный раствор буфера на основе глутаминовой кислоты и антитело, специфично связывающееся с рецептором A IL-17 человека в концентрации приблизительно от 140 до 280 мг/мл, и глутаминовую кислоту в концентрации 300,2 Мм; pH 4,5-5,20,2; 30,2% пролина (мас./об.) и 0,010,002% (мас./об.) полисорбата 20; причем его вязкость составляет 5-7 сПз при 25С. Также частью изобретения являются фармацевтический контейнер, содержащий состав, и набор, содержащий контейнер. Кроме того, описаны способы лечения псориаза, псориатического артрита, астмы, анкилозирующего спондилита и рассеянного склероза у взрослого человека, предусматривающие введение состава по изобретению.
EA201290653A 2010-01-15 2011-01-12 Фармацевтический состав антитела для лечения воспалительного заболевания и способы его применения EA031209B9 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US29538710P 2010-01-15 2010-01-15
US42205910P 2010-12-10 2010-12-10
PCT/US2011/020985 WO2011088120A1 (en) 2010-01-15 2011-01-12 Antibody formulation and therapeutic regimens

Publications (3)

Publication Number Publication Date
EA201290653A1 EA201290653A1 (ru) 2013-02-28
EA031209B1 EA031209B1 (ru) 2018-12-28
EA031209B9 true EA031209B9 (ru) 2021-11-19

Family

ID=43858045

Family Applications (2)

Application Number Title Priority Date Filing Date
EA201290653A EA031209B9 (ru) 2010-01-15 2011-01-12 Фармацевтический состав антитела для лечения воспалительного заболевания и способы его применения
EA201891433A EA201891433A3 (ru) 2010-01-15 2011-01-12 Состав антитела и терапевтические режимы

Family Applications After (1)

Application Number Title Priority Date Filing Date
EA201891433A EA201891433A3 (ru) 2010-01-15 2011-01-12 Состав антитела и терапевтические режимы

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US (5) US8883151B2 (ru)
EP (3) EP2523688B1 (ru)
JP (2) JP5743234B2 (ru)
KR (1) KR101766936B1 (ru)
CN (1) CN102821787B (ru)
AR (1) AR079903A1 (ru)
AU (3) AU2011205402B2 (ru)
BR (1) BR112012017150B1 (ru)
CA (1) CA2787128C (ru)
CL (1) CL2012001966A1 (ru)
CO (1) CO6640206A2 (ru)
CR (1) CR20120419A (ru)
CY (2) CY1119852T1 (ru)
DK (2) DK3295957T3 (ru)
EA (2) EA031209B9 (ru)
ES (2) ES2652637T3 (ru)
HR (1) HRP20171939T1 (ru)
HU (2) HUE035618T2 (ru)
IL (1) IL220602B (ru)
IN (1) IN2012DN06720A (ru)
LT (2) LT2523688T (ru)
MA (1) MA33989B1 (ru)
MX (1) MX349856B (ru)
MY (1) MY182680A (ru)
NO (1) NO2523688T3 (ru)
NZ (1) NZ601125A (ru)
PE (1) PE20121691A1 (ru)
PH (1) PH12012501364A1 (ru)
PL (2) PL3295957T3 (ru)
PT (2) PT2523688T (ru)
RS (2) RS56781B1 (ru)
SG (2) SG10201604093XA (ru)
SI (2) SI3295957T1 (ru)
TN (1) TN2012000335A1 (ru)
TW (1) TWI554282B (ru)
UA (1) UA112288C2 (ru)
WO (1) WO2011088120A1 (ru)
ZA (1) ZA201205167B (ru)

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