DK3498292T3 - Uspa2-proteinkonstruktioner og anvendelser deraf - Google Patents

Uspa2-proteinkonstruktioner og anvendelser deraf Download PDF

Info

Publication number: DK3498292T3
Authority: DK; Denmark
Prior art keywords: protein constructions; uspa2 protein; uspa2; constructions; protein
Prior art date: 2014-02-24

Application number

DK18211544.4T

Other languages

English (en)

Inventor

Normand Blais

Cindy Castado

Patrick Chomez

Marianne Dewerchin

Original Assignee

Glaxosmithkline Biologicals Sa

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2014-02-24

Filing date

2015-02-20

Publication date

2022-01-03

2015-02-20 Application filed by Glaxosmithkline Biologicals Sa filed Critical Glaxosmithkline Biologicals Sa

2022-01-03 Application granted granted Critical

2022-01-03 Publication of DK3498292T3 publication Critical patent/DK3498292T3/da

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/21—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
- C07K14/212—Moraxellaceae, e.g. Acinetobacter, Moraxella, Oligella, Psychrobacter
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/095—Neisseria
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/104—Pseudomonadales, e.g. Pseudomonas
- A61K39/1045—Moraxella
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/22—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Neisseriaceae (F)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/1217—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Neisseriaceae (F)
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
- C07K16/1203—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria
- C07K16/1218—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-negative bacteria from Acinetobacter
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55566—Emulsions, e.g. Freund's adjuvant, MF59
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55572—Lipopolysaccharides; Lipid A; Monophosphoryl lipid A
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55577—Saponins; Quil A; QS21; ISCOMS
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/70—Multivalent vaccine
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2121/00—Preparations for use in therapy
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

Health & Medical Sciences (AREA)
Chemical & Material Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Medicinal Chemistry (AREA)
General Health & Medical Sciences (AREA)
Organic Chemistry (AREA)
Immunology (AREA)
Animal Behavior & Ethology (AREA)
Pharmacology & Pharmacy (AREA)
Public Health (AREA)
Veterinary Medicine (AREA)
Epidemiology (AREA)
Mycology (AREA)
Microbiology (AREA)
Molecular Biology (AREA)
Biophysics (AREA)
Proteomics, Peptides & Aminoacids (AREA)
Biochemistry (AREA)
Genetics & Genomics (AREA)
Chemical Kinetics & Catalysis (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
General Chemical & Material Sciences (AREA)
Gastroenterology & Hepatology (AREA)
Bioinformatics & Cheminformatics (AREA)
Engineering & Computer Science (AREA)
Communicable Diseases (AREA)
Oncology (AREA)
Pulmonology (AREA)
Peptides Or Proteins (AREA)
Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Medicines Containing Material From Animals Or Micro-Organisms (AREA)

DK18211544.4T 2014-02-24 2015-02-20 Uspa2-proteinkonstruktioner og anvendelser deraf DK3498292T3 (da)

Applications Claiming Priority (4)

Application Number	Priority Date	Filing Date	Title
US201461943909P	2014-02-24	2014-02-24
US201461946937P	2014-03-03	2014-03-03
US201461946932P	2014-03-03	2014-03-03
EP15708341.1A EP3110438B1 (en)	2014-02-24	2015-02-20	Uspa2 protein constructs and uses thereof

Publications (1)

Publication Number	Publication Date
DK3498292T3 true DK3498292T3 (da)	2022-01-03

Family

ID=52629643

Family Applications (2)

Application Number	Title	Priority Date	Filing Date
DK15708341.1T DK3110438T3 (da)	2014-02-24	2015-02-20	Uspa2 proteinkonstrukter og anvendelser deraf
DK18211544.4T DK3498292T3 (da)	2014-02-24	2015-02-20	Uspa2-proteinkonstruktioner og anvendelser deraf

Family Applications Before (1)

Application Number	Title	Priority Date	Filing Date
DK15708341.1T DK3110438T3 (da)	2014-02-24	2015-02-20	Uspa2 proteinkonstrukter og anvendelser deraf

Country Status (28)

Country	Link
US (3)	US10040832B2 (da)
EP (2)	EP3110438B1 (da)
JP (1)	JP6585085B2 (da)
KR (1)	KR102515835B1 (da)
CN (2)	CN106061995A (da)
AU (1)	AU2015220369B2 (da)
BE (1)	BE1022345A9 (da)
BR (1)	BR112016019525B1 (da)
CA (1)	CA2939862C (da)
CY (2)	CY1121535T1 (da)
DK (2)	DK3110438T3 (da)
EA (1)	EA034352B1 (da)
ES (2)	ES2715674T3 (da)
HR (2)	HRP20190412T1 (da)
HU (2)	HUE042054T2 (da)
IL (1)	IL246994B (da)
LT (2)	LT3110438T (da)
ME (1)	ME03335B (da)
MX (1)	MX376079B (da)
PL (2)	PL3498292T3 (da)
PT (2)	PT3498292T (da)
RS (2)	RS58451B1 (da)
SG (1)	SG11201606272PA (da)
SI (2)	SI3110438T1 (da)
SM (2)	SMT202100728T1 (da)
TW (1)	TW201620927A (da)
UY (1)	UY36006A (da)
WO (1)	WO2015125118A1 (da)

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TW201620927A (zh) *	2014-02-24	2016-06-16	葛蘭素史密斯克藍生物品公司	Ｕｓｐａ２蛋白質構築體及其用途
GB201621686D0 (en)	2016-12-20	2017-02-01	Glaxosmithkline Biologicals Sa	Novel methods for inducing an immune response
EP3600391A1 (en)	2017-03-31	2020-02-05	GlaxoSmithKline Intellectual Property Development Limited	Immunogenic composition, use and method of treatment
WO2018178265A1 (en)	2017-03-31	2018-10-04	Glaxosmithkline Intellectual Property Development Limited	Immunogenic composition, use and method of treatment
US12016919B2 (en)	2017-05-30	2024-06-25	Glaxosmithkline Biologicals Sa	Methods for manufacturing an adjuvant
JP2020530478A (ja) *	2017-08-14	2020-10-22	グラクソスミスクラインバイオロジカルズソシエテアノニム	免疫応答を強化する方法
MX2020005481A (es)	2017-12-01	2020-12-07	Glaxosmithkline Biologicals Sa	Purificacion de saponina.
GB201803692D0 (en) *	2018-03-08	2018-04-25	Glaxosmithkline Biologicals Sa	Immunogenic composition
MX2021001479A (es)	2018-08-07	2021-04-28	Glaxosmithkline Biologicals Sa	Novedosos procesos y vacunas.
CN112912097A (zh) *	2018-08-23	2021-06-04	葛兰素史密丝克莱恩生物有限公司	免疫原性蛋白和组合物
EP3886901A1 (en)	2018-11-29	2021-10-06	GlaxoSmithKline Biologicals S.A.	Methods for manufacturing an adjuvant
US20220221455A1 (en)	2019-04-18	2022-07-14	Glaxosmithkline Biologicals Sa	Antigen binding proteins and assays
WO2020245207A1 (en)	2019-06-05	2020-12-10	Glaxosmithkline Biologicals Sa	Saponin purification
BR112021026775A2 (pt)	2019-08-05	2022-05-10	Glaxosmithkline Biologicals Sa	Processo para preparar uma composição que compreende um polipeptídeo de proteína d
EP4010014A1 (en)	2019-08-05	2022-06-15	GlaxoSmithKline Biologicals S.A.	Immunogenic composition
US20230266317A1 (en)	2019-09-11	2023-08-24	Glaxosmithkline Biologicals Sa	Antigen binding protein and assays
WO2022175423A1 (en)	2021-02-22	2022-08-25	Glaxosmithkline Biologicals Sa	Immunogenic composition, use and methods
WO2024017827A1 (en)	2022-07-19	2024-01-25	Glaxosmithkline Biologicals Sa	Continuous process for vaccine production

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AU685443B2 (en)	1993-03-23	1998-01-22	Smithkline Beecham Biologicals (Sa)	Vaccine compositions containing 3-O deacylated monophosphoryl lipid A
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CA2274495C (en) *	1996-12-20	2009-06-02	Board Of Regents, The University Of Texas System	Uspa1 and uspa2 antigens of moraxella catarrhalis
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BR0211494A (pt) *	2001-07-27	2004-08-17	Chiron Srl	Adesinas de meningococo nada, app e orf 40
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TW201620927A (zh) *	2014-02-24	2016-06-16	葛蘭素史密斯克藍生物品公司	Ｕｓｐａ２蛋白質構築體及其用途

2015
- 2015-02-17 TW TW104105745A patent/TW201620927A/zh unknown
- 2015-02-20 CA CA2939862A patent/CA2939862C/en active Active
- 2015-02-20 US US15/119,220 patent/US10040832B2/en active Active
- 2015-02-20 SI SI201530667T patent/SI3110438T1/sl unknown
- 2015-02-20 HR HRP20190412TT patent/HRP20190412T1/hr unknown
- 2015-02-20 RS RS20190297A patent/RS58451B1/sr unknown
- 2015-02-20 HU HUE15708341A patent/HUE042054T2/hu unknown
- 2015-02-20 AU AU2015220369A patent/AU2015220369B2/en not_active Ceased
- 2015-02-20 CN CN201580010155.6A patent/CN106061995A/zh active Pending
- 2015-02-20 SG SG11201606272PA patent/SG11201606272PA/en unknown
- 2015-02-20 WO PCT/IB2015/051308 patent/WO2015125118A1/en not_active Ceased
- 2015-02-20 JP JP2016570199A patent/JP6585085B2/ja not_active Expired - Fee Related
- 2015-02-20 ES ES15708341T patent/ES2715674T3/es active Active
- 2015-02-20 LT LTEP15708341.1T patent/LT3110438T/lt unknown
- 2015-02-20 LT LTEP18211544.4T patent/LT3498292T/lt unknown
- 2015-02-20 EP EP15708341.1A patent/EP3110438B1/en active Active
- 2015-02-20 MX MX2016010954A patent/MX376079B/es active IP Right Grant
- 2015-02-20 BR BR112016019525-6A patent/BR112016019525B1/pt not_active IP Right Cessation
- 2015-02-20 UY UY0001036006A patent/UY36006A/es not_active Application Discontinuation
- 2015-02-20 RS RS20211446A patent/RS62592B1/sr unknown
- 2015-02-20 KR KR1020167022954A patent/KR102515835B1/ko active Active
- 2015-02-20 HR HRP20211926TT patent/HRP20211926T1/hr unknown
- 2015-02-20 PL PL18211544T patent/PL3498292T3/pl unknown
- 2015-02-20 DK DK15708341.1T patent/DK3110438T3/da active
- 2015-02-20 ME MEP-2019-54A patent/ME03335B/me unknown
- 2015-02-20 SI SI201531759T patent/SI3498292T1/sl unknown
- 2015-02-20 SM SM20210728T patent/SMT202100728T1/it unknown
- 2015-02-20 HU HUE18211544A patent/HUE057505T2/hu unknown
- 2015-02-20 EP EP18211544.4A patent/EP3498292B1/en active Active
- 2015-02-20 EA EA201691611A patent/EA034352B1/ru not_active IP Right Cessation
- 2015-02-20 PT PT182115444T patent/PT3498292T/pt unknown
- 2015-02-20 PT PT15708341T patent/PT3110438T/pt unknown
- 2015-02-20 BE BE20155094A patent/BE1022345A9/fr not_active IP Right Cessation
- 2015-02-20 SM SM20190166T patent/SMT201900166T1/it unknown
- 2015-02-20 PL PL15708341T patent/PL3110438T3/pl unknown
- 2015-02-20 CN CN202010194047.1A patent/CN111499701A/zh active Pending
- 2015-02-20 ES ES18211544T patent/ES2899300T3/es active Active
- 2015-02-20 DK DK18211544.4T patent/DK3498292T3/da active
2016
- 2016-07-28 IL IL246994A patent/IL246994B/en active IP Right Grant
2018
- 2018-06-29 US US16/023,164 patent/US10745449B2/en active Active
2019
- 2019-03-14 CY CY20191100307T patent/CY1121535T1/el unknown
2020
- 2020-06-29 US US16/914,750 patent/US10947280B2/en active Active
2021
- 2021-11-30 CY CY20211101038T patent/CY1124979T1/el unknown

Also Published As

Publication number	Publication date
RS62592B1 (sr)	2021-12-31
JP6585085B2 (ja)	2019-10-02
EP3110438A1 (en)	2017-01-04
LT3498292T (lt)	2021-11-25
EA034352B1 (ru)	2020-01-30
UY36006A (es)	2015-09-30
ES2715674T3 (es)	2019-06-05
WO2015125118A1 (en)	2015-08-27
PT3498292T (pt)	2021-11-18
SI3498292T1 (sl)	2022-01-31
EA201691611A1 (ru)	2016-12-30
CY1124979T1 (el)	2022-11-25
ES2899300T3 (es)	2022-03-10
PL3498292T3 (pl)	2022-02-14
US20200325184A1 (en)	2020-10-15
US10745449B2 (en)	2020-08-18
US20180354996A1 (en)	2018-12-13
SMT202100728T1 (it)	2022-01-10
BE1022345A9 (fr)	2016-11-16
KR102515835B1 (ko)	2023-03-31
US10040832B2 (en)	2018-08-07
PL3110438T3 (pl)	2019-06-28
US10947280B2 (en)	2021-03-16
AU2015220369A1 (en)	2016-09-15
MX2016010954A (es)	2016-11-11
BR112016019525B1 (pt)	2024-01-02
SMT201900166T1 (it)	2019-05-10
HUE057505T2 (hu)	2022-05-28
CA2939862C (en)	2022-12-06
DK3110438T3 (da)	2019-03-25
SI3110438T1 (sl)	2019-05-31
EP3498292A1 (en)	2019-06-19
HRP20211926T1 (hr)	2022-03-18
IL246994B (en)	2020-11-30
EP3498292B1 (en)	2021-10-20
HRP20190412T1 (hr)	2019-04-19
US20170008932A1 (en)	2017-01-12
IL246994A0 (en)	2016-09-29
AU2015220369B2 (en)	2018-02-01
CN111499701A (zh)	2020-08-07
BE1022345B1 (fr)	2016-03-25
MX376079B (es)	2025-03-07
LT3110438T (lt)	2019-04-10
RS58451B1 (sr)	2019-04-30
CA2939862A1 (en)	2015-08-27
PT3110438T (pt)	2019-03-29
JP2017507181A (ja)	2017-03-16
TW201620927A (zh)	2016-06-16
CY1121535T1 (el)	2020-05-29
SG11201606272PA (en)	2016-09-29
KR20160124774A (ko)	2016-10-28
HUE042054T2 (hu)	2019-06-28
CN106061995A (zh)	2016-10-26
EP3110438B1 (en)	2019-01-02
BR112016019525A2 (pt)	2017-10-24
ME03335B (me)	2019-10-20

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